A dihydro-pyrido-indole potently inhibits HSV-1 infection by interfering the viral immediate early transcriptional events

Antiviral Research

Volumn 105, Issue 1, 2014, Pages 126-134

  Bag, Paromita ^a   Ojha, Durbadal ^a   Mukherjee, Hemanta ^a   Halder, Umesh C ^b   Mondal, Supriya ^a   Biswas, Aruna ^a   Sharon, Ashoke ^c   Van Kaer, Luc ^d   Chakrabarty, Sekhar ^a   Das, Gobardhan ^e   Mitra, Debashis ^f   Chattopadhyay, Debprasad ^a  

^a INDIAN COUNCIL OF MEDICAL RESEARCH   (India)

^b NATIONAL INSTITUTE OF CHOLERA AND ENTERIC DISEASES   (India)

^c BIRLA INSTITUTE OF TECHNOLOGY   (India)

^d VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^e UNIVERSITY OF KWAZULU NATAL   (South Africa)

^f NATIONAL CENTRE FOR CELL SCIENCE   (India)

Author keywords

Ethnomedicine; HSV; Immediate early transcription; LSD1; Ophiorrhiza nicobarica

Indexed keywords

ACICLOVIR; ANTIVIRUS AGENT; HARMALINE; IMMEDIATE EARLY PROTEIN; HERPES SIMPLEX VIRUS, TYPE 1 PROTEIN ICP4; ICP27 PROTEIN, HUMAN HERPESVIRUS 1; 7 METHOXY 1 METHYL 4,9 DIHYDRO 3H PYRIDO[3,4 B]INDOLE; INDOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DOWN REGULATION; DRUG POTENCY; FEMALE; GENE EXPRESSION; GENE SYNTHESIS; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1 (STRAIN F); IN VITRO STUDY; LATENT PERIOD; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL TIME; VIRUS ENTRY; VIRUS REACTIVATION; VIRUS REPLICATION; VIRUS TRANSCRIPTION; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; BIOSYNTHESIS; CHEMISTRY; DISEASE MODEL; DRUG EFFECTS; GENETIC TRANSCRIPTION; GENETICS; HERPES SIMPLEX VIRUS 1; ISOLATION AND PURIFICATION; RUBIACEAE; VIROLOGY; CARBON NUCLEAR MAGNETIC RESONANCE; COMPARATIVE STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG ISOLATION; ELECTROSPRAY; GEL MOBILITY SHIFT ASSAY; IMMUNOBLOTTING; IMMUNOPRECIPITATION; REAL TIME POLYMERASE CHAIN REACTION; TIME OF FLIGHT MASS SPECTROMETRY; VERO CELL LINE; VIRUS LATENCY; WESTERN BLOTTING; WILD TYPE;

ANIMALS; ANTIVIRAL AGENTS; DISEASE MODELS, ANIMAL; FEMALE; HARMALINE; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; IMMEDIATE-EARLY PROTEINS; MICE, INBRED BALB C; RUBIACEAE; TRANSCRIPTION, GENETIC;

EID: 84897457926     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2014.02.007     Document Type: Article

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