Vasorelaxant effects of harmine and harmaline extracted from Peganum harmala L. seed's in isolated rat aorta

Pharmacological Research

Volumn 54, Issue 2, 2006, Pages 150-157

  Berrougui, Hicham ^a,b,c   Martín Cordero, Carmen ^b   Khalil, Abdelouahed ^c   Hmamouchi, Mohammed ^a   Ettaib, Abdelkader ^a   Marhuenda, Elisa ^b   Herrera, María Dolores ^b  

^a MOHAMMED V UNIVERSITY   (Morocco)

^b UNIVERSITY OF SEVILLE   (Spain)

^c UNIVERSITÉ DE SHERBROOKE   (Canada)

Author keywords

Antioxidant; Endothelium; Harmaline; Harmine; Peganum harmala L.; Rat aorta; Vasorelaxant response

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ALKALOID DERIVATIVE; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA TOCOPHEROL; ANTIOXIDANT; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; CYCLIC AMP; CYCLIC GMP; DILTIAZEM; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FREE RADICAL; HARMALINE; HARMINE; INDOMETACIN; ISOBUTYLMETHYLXANTHINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PEGANUM HARMALA EXTRACT; PHENYLEPHRINE; PHOSPHODIESTERASE INHIBITOR; POTASSIUM CHLORIDE; PRAZOSIN; PROSTACYCLIN; PROSTAGLANDIN SYNTHASE INHIBITOR; SCAVENGER;

ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; AORTA; ARTERY CONSTRICTION; ARTERY DILATATION; ARTICLE; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG RESPONSE; EVOKED RESPONSE; IC 50; NONHUMAN; PEGANUM HARMALA; PLANT SEED; PRIORITY JOURNAL; RAT; SECOND MESSENGER; VASCULAR ENDOTHELIUM; VASCULAR RING;

ANIMALS; AORTA, THORACIC; DOSE-RESPONSE RELATIONSHIP, DRUG; HARMALINE; HARMINE; MOLECULAR STRUCTURE; MUSCLE, SMOOTH, VASCULAR; PEGANUM; PLANT EXTRACTS; RATS; RATS, WISTAR; SEEDS; VASODILATION; VASODILATOR AGENTS;

EID: 33745862707     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2006.04.001     Document Type: Article

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