PMPA and PMEA prodrugs for the treatment of HIV infections and human papillomavirus (HPV) associated neoplasia and cancer

European Journal of Medicinal Chemistry

Volumn 78, Issue , 2014, Pages 259-268

  Pertusati, Fabrizio ^a   Hinsinger, Karen ^a   Flynn, Áine Sinéad ^a   Powell, Ned ^a   Tristram, Amanda ^a   Balzarini, Jan ^b   McGuigan, Christopher ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

5,6,7,8 Tetrahydro 1 naphthol; Antiproliferative activity; HIV; HPV; PMPA PMEA

Indexed keywords

ADEFOVIR; ALANINE; ESTER DERIVATIVE; PHOSPHONIC ACID DERIVATIVE; TENOFOVIR; TRIMETHYLSILYL DERIVATIVE; ADENINE; ANTINEOPLASTIC AGENT; ANTIVIRUS AGENT; PRODRUG;

ANIMAL CELL; ANTIPROLIFERATIVE ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOSTASIS; DISEASE ASSOCIATION; DNA VIRUS INFECTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN PAPILLOMAVIRUS ASSOCIATED CANCER; HUMAN PAPILLOMAVIRUS ASSOCIATED NEOPLASIA; IN VITRO STUDY; MOUSE; NONHUMAN; VIRUS TRANSFORMATION; ANALOGS AND DERIVATIVES; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; HELA CELL LINE; HIV INFECTIONS; HUMAN IMMUNODEFICIENCY VIRUS; MICROBIAL SENSITIVITY TEST; PAPILLOMAVIRUS INFECTIONS; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL CULTURE;

ADENINE; ANTINEOPLASTIC AGENTS; ANTIVIRAL AGENTS; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HELA CELLS; HIV; HIV INFECTIONS; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; ORGANOPHOSPHONATES; PAPILLOMAVIRUS INFECTIONS; PRODRUGS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 84897453816     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2014.03.051     Document Type: Article

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