Prevalence of carbapenemase-producing bacteria in hospitals in Saxony, Germany;Prävalenzerhebung zum Vorkommen von Carbapenemase-Bildnern in sächsischen Kliniken

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz

Volumn 57, Issue 4, 2014, Pages 406-413

  Ehrhard, I ^a   Karaalp, A K ^a   Hackel, T ^a   Holl G ^a   Rodewald, N ^a   Reif, U ^a   Kaase, M ^b   Eckmanns, T ^c   Sydow, W ^d  

^a Abteilung Medizinische Mikrobiologie Landesuntersuchungsanstalt für das Gesundheits und Veterinärwesen Sachsen   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

^c ROBERT KOCH INSTITUTE   (Germany)

^d Referat Öffentlicher Gesundheitsdienst Infektionsschutz Umweltbezogener Gesundheitsschutz Sächsisches Staatsministerium für Soziales und Verbraucherschutz ^*  (Germany)

Author keywords

Carbapenemase; Klebsiella pneumoniae; KPC 2; Multidrug resistance; Saxony

Indexed keywords

BACTERIAL PROTEIN; BETA LACTAMASE; CARBAPENEMASE-2, KLEBSIELLA PNEUMONIAE;

ADOLESCENT; ADULT; AGED; CHILD; CROSS INFECTION; ENZYMOLOGY; FEMALE; GERMANY; HOSPITALIZATION; HUMAN; INFANT; ISOLATION AND PURIFICATION; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MALE; METABOLISM; MICROBIOLOGY; MIDDLE AGED; NEWBORN; PRESCHOOL CHILD; PREVALENCE; RISK FACTOR; STATISTICS AND NUMERICAL DATA; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BACTERIAL PROTEINS; BETA-LACTAMASES; CHILD; CHILD, PRESCHOOL; CROSS INFECTION; FEMALE; GERMANY; HOSPITALIZATION; HUMANS; INFANT; INFANT, NEWBORN; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MALE; MIDDLE AGED; PREVALENCE; RISK FACTORS; YOUNG ADULT;

EID: 84897445299     PISSN: 14369990     EISSN: 14371588     Source Type: Journal    
DOI: 10.1007/s00103-013-1914-z     Document Type: Article

References (34)

1. Kaase M (2012) Carbapenemases in gram-negative bacteria. Current data and trends of resistance resulting from the work of national reference centres. Bundesgesundheitsbl Gesundheitsforsch Gesundheitsschutz 55:1401-1404
2. Pfeifer Y (2010) ESBL, AmpC and carbapenemases: emergence, dissemination and diagnostics of β-lactamase-producing Gram-negative pathogens. J Lab Med 34:205-215
3. Pfeifer Y, Cullik A, Witte W (2010) Resistance to cephalosporins and carbapenems in Gram-negative bacterial pathogens. Int J Med Microbiol 300:371-379
4. Baum H von, Dettenkofer M, Heeg P, et al. (2010) Konsensusempfehlung Baden-Württemberg: Umgang mit Patienten mit hochresistenten Enterobakterien inklusive ESBL-Bildnern. Hyg Med 35:40-45
5. Hussein K, Sprecher H, Mashiach T, et al. (2009) Carbapenem resistance among Klebsiella pneumoniae isolates: risk factors, molecular characteristics, and susceptibility patterns. Infect Control Hosp Epidemiol 30:666-671
6. Carrër A, Fortineau N, Nordmann P (2010) Use of ChromID extended-spectrum beta-lactamase medium for detecting carbapenemase-producing Enterobacteriaceae. J Clin Microbiol 48:1913-1914
7. Kaase M (2010) Carbapenemase-Detektion im mikrobiologischen Labor. Hyg Med 35:32-36
8. European Committee on Antimicrobial Susceptibility Testing (EUCAST) (2012) Breakpoint tables for interpretation of MICs and zone diameters. http://www.eucast.org, Version 2.0
9. Centers for Disease Control and Prevention (2011) Multiplex Real-time PCR detection of Klebsiella pneumoniae Carbapenemase (KPC) and New Delhi Metallo-β-lactamase (NDM-1) genes. http://www.cdc.gov/HAI/settings/lab/kpc- ndm1-lab-protocol.html
10. Yigit H, Queenan AM, Anderson GJ, et al. (2001) Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae. Antimicrob Agents Chemother 45:1151-1161
11. Pitout JDD, Gregson DB, Poirel L, et al. (2005) Detection of Pseudomonas aeruginosa producing metallo-beta-lactamases in a large centralized laboratory. J Clin Microbiol 43:3129-3135
12. Juan C, Beceiro A, Gutiérrez O, et al. (2008) Characterization of the new metallo-beta-lactamase VIM-13 and its integron-borne gene from a Pseudomonas aeruginosa clinical isolate in Spain. Antimicrob Agents Chemother 52:3589-3596
13. Kaase M, Szabados F, Wassill L, Gatermann SG (2012) Detection of carbapenemases in Enterobacteriaceae by a commercial multiplex PCR. J Clin Microbiol 50:3115-3118
14. Poirel L, Heretier C, Tolün V, Nordmann P (2011) Emergence of oxacillinase-mediated resistance to imipenem in Klebsiella pneumoniae. Antimicrob Agents Chemother 48:15-22
15. Standard Operating Procedure for PulseNet PFGE of Escherichia coli O157:H7, Escherichia coli non-O157 (STEC), Salmonella serotypes, Shigella sonnei and Shigella flexneri. http://www.cdc.gov/pulsenet/PDF/ecoli-shigella- salmonella-pfge-protocol-508c.pdf. Zugegriffen: 17. Juni 2013
16. Tenover FC, Arbeit RD, Goehring RV, et al. (1995) Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel elektrophoresis: criteria for bacterial strain typing. J Clin Microbiol 33:2233-2239
17. Empfehlung der Kommission für Krankenhaushygiene und Infektionsprävention (KRINKO) beim Robert Koch-Institut (RKI) (2012) Hygienemaßnahmen bei Infektionen oder Besiedlung mit multiresistenten gramnegativen Stäbchen. Bundesgesundheitsbl Gesundheitsforsch Gesundheitsschutz 55:1311-1354
18. Thurlow CJ, Prabaker K, Lin MY, et al. (2013) Anatomic sites of patient colonization and environmental contamination with Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae at long-term acute care hospitals. Infect Control Hosp Epidemiol 34:56-61
19. Tzouvelekis LS, Markogiannakis A, Psichogiou M, et al. (2012) Carbapenemases in Klebsiella pneumoniae and other Enterobacteriaceae: an evolving crisis of global dimensions. Clin Microbiol Rev 25:682-707
20. Robert Koch-Institut (2011) Zum Auftreten von Enterobacteriaceae mit OXA-48-Carbapenemase in Deutschland. Epidemiol Bull 32:304-306
21. Robert Koch-Institut (2013) Zur aktuellen Situation bei Carbapenemase-bildenden gramnegativen Bakterien. Epidemiol Bull 19:167-171
22. Wiener-Well Y, Rudensky B, Yinnon AM, et al. (2010) Carriage rate of carbapenem-resistant Klebsiella pneumoniae in hospitalised patients during a national outbreak. J Hosp Infect 74:344-349
23. Ben-David D, Masarwa S, Navon-Venezia S, et al. (2011) Carbapenem-resistant Klebsiella pneumoniae in post-acute-care facilities in Israel. Infect Control Hosp Epidemiol 32:845-853
24. Lin MY, Lyles-Banks RD, Lolans K, et al. (2013) The importance of long-term acute care hospitals in the regional epidemiology of Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae. Clin Infect Dis 57:1246-1252
25. Lin MY, Lyles-Banks RD, Lolans K, et al. (2011) Prevalence of Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae (KPC) among adult patients in intensive care units (ICUs) and long-term acute care hospitals (LTACHs) in the Chicago region. 49th Annual Scientific Meeting of the IDSA 2011, 20.-23. Oktober 2011. Boston (Abstract 396)
26. Burns K, Morris D, Murchan S, et al. (2013) Carbapenemase-producing Enterobacteriaceae in Irish critical care units: results of a pilot prevalence survey, June 2011. J Hosp Infect 83:71-73
27. Sächsisches Staatsministerium für Soziales und Verbraucherschutz (2012) Bekanntmachung des Sächsischen Staatsministeriums für Soziales und Verbraucherschutz zum Krankenhausplan des Freistaates Sachsen. Stand: 1. Januar 2012 (10. Fortschreibung). Vom 10. Januar 2012. SächsABl 1:1-68
28. Perez F, Endimiani A, Ray AJ, et al. (2010) Carbapenem-resistant Acinetobacter baumannii and Klebsiella pneumoniae across a hospital system: impact of post-acute care facilities on dissemination. J Antimicrob Chemother 65:1807-1818
29. Humphries RM, Kelesidis T, Bard JD, et al. (2010) Successful treatment of pan-resistant Klebsiella pneumoniae pneumonia and bacteraemia with a combination of high-dose tigecycline and colistin. J Med Microbiol 59:1383-1389
30. O'Fallon E, Gautam S, D'Agata EMC (2009) Colonization with multidrug-resistant gram-negative bacteria: prolonged duration and frequent colonization. Clin Infect Dis 48:1375-1381
31. Zimmermann FS, Assous MV, Bdolah-Abram T, et al. (2013) Duration of carriage of carbapenem-resistant Enterobacteriaceae following hospital discharge. Am J Infect Control 41:190-194
32. Nordmann P, Naas T, Poirel L (2011) Global spread of carbapenemase- producing Enterobacteriaceae. Emerg Infect Dis 17:1791-1798
33. Pfeifer Y, Eller C, Leistner R, et al. (2013) ESBL-Bildner als Infektionsquelle beim Menschen und die Frage nach dem zoonotischen Reservoir. Hyg Med 38:294-299
34. Hara GL, Gould I, Endimiani A, et al. (2013) Detection, treatment, and prevention of carbapenemase-producing Enterobacteriaceae: recommendations from an International Working Group. J Chemotherapy 25:129-140