Antioxidant Vitamin C attenuates experimental abdominal aortic aneurysm development in an elastase-induced rat model

Journal of Surgical Research

Volumn 188, Issue 1, 2014, Pages 316-325

  Shang, Tao ^a   Liu, Zhao ^a   Liu, Chang Jian ^a  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

Author keywords

Abdominal aortic aneurysm; Inflammation; Oxidative stress; Vitamin C

Indexed keywords

8 HYDROXYGUANINE; 8 ISOPROSTANE; ASCORBIC ACID; ELASTASE; ELASTIN; GELATINASE A; GELATINASE B; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; PLACEBO; SODIUM CHLORIDE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TUMOR NECROSIS FACTOR ALPHA;

ABDOMINAL AORTA ANEURYSM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; AORTA; ARTERY DILATATION; ARTICLE; BIOCHEMISTRY; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; ENZYME INHIBITION; GENE EXPRESSION; HISTOPATHOLOGY; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SHAM PROCEDURE; UPREGULATION;

ABDOMINAL AORTIC ANEURYSM; INFLAMMATION; OXIDATIVE STRESS; VITAMIN C;

ANIMALS; ANTIOXIDANTS; AORTA, ABDOMINAL; AORTIC ANEURYSM, ABDOMINAL; ASCORBIC ACID; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; INFLAMMATION; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; OXIDATIVE STRESS; PANCREATIC ELASTASE; RANDOM ALLOCATION; RATS;

EID: 84897441038     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2013.11.1105     Document Type: Article

References (30)

1. K.C. Kent, R.M. Zwolak, and N.N. Egorova et al. Analysis of risk factors for abdominal aortic aneurysm in a cohort of more than 3 million individuals J Vasc Surg 52 2010 539
2. G. Ailawadi, J.L. Eliason, and G.R. Upchurch Jr. Current concepts in the pathogenesis of abdominal aortic aneurysm J Vasc Surg 38 2003 584
3. F.A. Lederle, G.R. Johnson, S.E. Wilson Veterans Affairs Cooperative Study #417 Investigators Rupture rate of large abdominal aortic aneurysms in patients refusing or unfit for elective repair JAMA 287 2002 2968
4. Mortality results for randomised controlled trial of early elective surgery or ultrasonographic surveillance for small abdominal aortic aneurysms. The UK Small Aneurysm Trial Participants Lancet 352 1998 1649
5. F.A. Lederle, S.E. Wilson, G.R. Johnson Aneurysm Detection and Management Veterans Affairs Cooperative Study Group Immediate repair compared with surveillance of small abdominal aortic aneurysms N Engl J Med 346 2002 1437
6. D.C. Brewster, J.L. Cronenwett, J.W. Hallett Jr., K.W. Johnston, W.C. Krupski, J.S. Matsumura Joint Council of the American Association for Vascular Surgery and Society for Vascular Surgery Guidelines for the treatment of abdominal aortic aneurysms. Report of a subcommittee of the Joint Council of the American Association for Vascular Surgery and Society for Vascular Surgery J Vasc Surg 37 2003 1106
7. C.M. Brophy, J.M. Reilly, G.J. Smith, and M.D. Tilson The role of inflammation in nonspecific abdominal aortic aneurysm disease Ann Vasc Surg 5 1991 229
8. T. Freestone, R.J. Turner, A. Coady, D.J. Higman, R.M. Greenhalgh, and J.T. Powell Inflammation and matrix metalloproteinases in the enlarging abdominal aortic aneurysm Arterioscler Thromb Vasc Biol 15 1995 1145
9. P.K. Shah Inflammation, metalloproteinases, and increased proteolysis: An emerging pathophysiological paradigm in aortic aneurysm Circulation 96 1997 2115
10. K.M. Newman, J. Jean-Claude, H. Li, W.G. Ramey, and M.D. Tilson Cytokines that activate proteolysis are increased in abdominal aortic aneurysms Circulation 90 1994 II224
11. A.E. Koch, G.K. Haines, and R.J. Rizzo et al. Human abdominal aortic aneurysms. Immunophenotypic analysis suggesting an immune-mediated response Am J Pathol 137 1990 1199
12. D. Gavrila, W.G. Li, and M.L. McCormick et al. Vitamin E inhibits abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice Arterioscler Thromb Vasc Biol 25 2005 1671
13. D. Praticò, M. Reilly, J.A. Lawson, and G.A. FitzGerald Novel indices of oxidant stress in cardiovascular disease: Specific analysis of F2-isoprostanes Agents Actions Suppl 48 1997 25
14. R. Alleva, F. Di Donato, and E. Strafella et al. Effect of ascorbic acid-rich diet on in vivo-induced oxidative stress Br J Nutr 107 2012 1645
15. L.V. d'Uscio, S. Milstien, D. Richardson, L. Smith, and Z.S. Katusic Long-term vitamin C treatment increases vascular tetrahydrobiopterin levels and nitric oxide synthase activity Circ Res 92 2003 88
16. H. Qiao, J. Bell, S. Juliao, L. Li, and J.M. May Ascorbic acid uptake and regulation of type I collagen synthesis in cultured vascular smooth muscle cells J Vasc Res 46 2009 15
17. A.C. Hospelhorn, B.M. Martin, and C. Franzblau Type IV collagen synthesis and accumulation in neonatal rat aortic smooth muscle cell cultures Matrix 12 1992 352
18. S. Anidjar, J.L. Salzmann, D. Gentric, P. Lagneau, J.P. Camilleri, and J.B. Michel Elastase-induced experimental aneurysms in rats Circulation 82 1990 973
19. K. Miwa, H. Nakashima, and M. Aoki et al. Inhibition of ets, an essential transcription factor for angiogenesis, to prevent the development of abdominal aortic aneurysm in a rat model Gene Ther 12 2005 1109
20. H. Nakashima, M. Aoki, and T. Miyake et al. Inhibition of experimental abdominal aortic aneurysm in the rat by use of decoy oligodeoxynucleotides suppressing activity of nuclear factor kappaB and ets transcription factors Circulation 109 2004 132
21. H. Aoki, K. Yoshimura, and M. Matsuzaki Turning back the clock: Regression of abdominal aortic aneurysms via pharmacotherapy J Mol Med 85 2007 1077
22. C.D. Liapis, and K.I. Paraskevas The pivotal role of matrix metalloproteinases in the development of human abdominal aortic aneurysms Vasc Med 8 2003 267
23. G.M. Longo, W. Xiong, T.C. Greiner, Y. Zhao, N. Fiotti, and B.T. Baxter Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms J Clin Invest 110 2002 625
24. K. Tsarouhas, G. Soufla, and S. Apostolakis et al. Transcriptional regulation of TIMPs in ascending aorta aneurysms Thromb Res 126 2010 399
25. K. Morimoto, T. Hasegawa, and A. Tanaka et al. Free-radical scavenger edaravone inhibits both formation and development of abdominal aortic aneurysm in rats J Vasc Surg 55 2012 1749
26. N. Yajima, M. Masuda, M. Miyazaki, N. Nakajima, S. Chien, and J.Y. Shyy Oxidative stress is involved in the development of experimental abdominal aortic aneurysm: A study of the transcription profile with complementary DNA microarray J Vasc Surg 36 2002 379
27. T. Shang, Z. Liu, M. Zhou, C.K. Zarins, C. Xu, and C.J. Liu Inhibition of experimental abdominal aortic aneurysm in a rat model by way of tanshinone A J Surg Res 178 2012 1029
28. M. Rentschler, and B.T. Baxter Pharmacological approaches to prevent abdominal aortic aneurysm enlargement and rupture Ann NY Acad Sci 1085 2006 39
29. R.W. Thompson, J.A. Curci, T.L. Ennis, D. Mao, M.B. Pagano, and C.T.N. Pham Pathophysiology of abdominal aortic aneurysms: Insights from the elastase-induced model in mice with different genetic backgrounds Ann NY Acad Sci 1085 2006 59
30. S. Shiraya, T. Miyake, and M. Aoki et al. Inhibition of development of experimental aortic abdominal aneurysm in rat model by atorvastatin through inhibition of macrophage migration Atherosclerosis 202 2009 34