Marked and persistent eosinophilia in the absence of clinical manifestations

Journal of Allergy and Clinical Immunology

Volumn 133, Issue 4, 2014, Pages

  Chen, Yun Yun K ^a   Khoury, Paneez ^a   Ware, Jeananne M ^a   Holland Thomas, Nicole C ^b   Stoddard, Jennifer L ^c   Gurprasad, Shakuntala ^c   Waldner, Amy J ^a   Klion, Amy D ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b SAIC FREDERICK INC   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

cytokine; Eosinophil; hypereosinophilic syndrome; pathogenesis

Indexed keywords

IMMUNOGLOBULIN E; INTERLEUKIN 13; IONOMYCIN; PHORBOL 13 ACETATE 12 MYRISTATE;

ADOLESCENT; ADULT; ARTICLE; CELL CULTURE; CELL POPULATION; CLINICAL EVALUATION; CONTROLLED STUDY; DISEASE DURATION; EOSINOPHIL COUNT; FEMALE; FLOW CYTOMETRY; HUMAN; HYPEREOSINOPHILIC SYNDROME; LYMPHOCYTE SUBPOPULATION; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SURFACE PROPERTY; YOUNG ADULT;

CYTOKINE; EOSINOPHIL; HYPEREOSINOPHILIC SYNDROME; PATHOGENESIS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHEMOKINE CCL17; CHILD; CYTOKINES; EOSINOPHILIA; EOSINOPHILS; FEMALE; HUMANS; HYPEREOSINOPHILIC SYNDROME; LEUKOCYTE COUNT; MALE; MIDDLE AGED; PHENOTYPE; T-LYMPHOCYTES; YOUNG ADULT;

EID: 84897437846     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2013.06.037     Document Type: Article

References (15)

1. H.U. Simon, M.E. Rothenberg, B.S. Bochner, P.F. Weller, A.J. Wardlaw, and M.E. Wechsler et al. Refining the definition of hypereosinophilic syndrome J Allergy Clin Immunol 126 2010 45 49
2. P. Valent, A.D. Klion, H.P. Horny, F. Roufosse, J. Gotlib, and P.F. Weller et al. Contemporary consensus proposal on criteria and classification of eosinophilic disorders and related syndromes J Allergy Clin Immunol 130 2012 607 612
3. J.W. Vardiman, J. Thiele, D.A. Arber, R.D. Brunning, M.J. Borowitz, and A. Porwit et al. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes Blood 114 2009 937 951
4. F. Roufosse, A. de Lavareille, L. Schandene, E. Cogan, A. Georgelas, and L. Wagner et al. Mepolizumab as a corticosteroid-sparing agent in lymphocytic variant hypereosinophilic syndrome J Allergy Clin Immunol 126 2010 828 835
5. T.M. Wilson, I. Maric, J. Shukla, M. Brown, C. Santos, and O. Simakova et al. IL-5 receptor a levels in patients with marked eosinophilia or mastocytosis J Allergy Clin Immunol 128 2011 1086 1092
6. H.U. Simon, S.G. Plotz, R. Dummer, and K. Blaser Abnormal clones of T cells producing interleukin-5 in idiopathic eosinophilia N Engl J Med 341 1999 1112 1120
7. A. de Lavareille, F. Roufosse, P. Schmid-Grendelmeier, A.S. Roumier, L. Schandene, and E. Cogan et al. High serum thymus and activation-regulated chemokine levels in the lymphocytic variant of the hypereosinophilic syndrome J Allergy Clin Immunol 110 2002 476 479
8. A.D. Klion, P. Noel, C. Akin, M.A. Law, D.G. Gilliland, and J. Cools et al. Elevated serum tryptase levels identify a subset of patients with a myeloproliferative variant of idiopathic hypereosinophilic syndrome associated with tissue fibrosis, poor prognosis, and imatinib responsiveness Blood 101 2003 4660 4666
9. L. Prin, J. Plumas, V. Gruart, S. Loiseau, D. Aldebert, and J.C. Ameisen et al. Elevated serum levels of soluble interleukin-2 receptor: a marker of disease activity in the hypereosinophilic syndrome Blood 78 1991 2626 2632
10. G. Helbig, A. Wieczorkiewicz, J. Dziaczkowska-Suszek, M. Majewski, and S. Kyrcz-Krzemien T-cell abnormalities are present at high frequencies in patients with hypereosinophilic syndrome Haematologica 94 2009 1236 1241
11. P.U. Ogbogu, B.S. Bochner, J.H. Butterfield, G.J. Gleich, J. Huss-Marp, and J.E. Kahn et al. Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy J Allergy Clin Immunol 124 2009 1319 1325.e3
12. C. Blanchard, M.K. Mingler, M. Vicario, J.P. Abonia, Y.Y. Wu, and T.X. Lu et al. IL-13 involvement in eosinohilic esophagitis: transcriptome analysis and reversibility with glucocorticoids J Allergy Clin Immunol 120 2007 1292 1300
13. J. Corren, R.F. Lemanske, N.A. Hanania, P.E. Korenblat, M.V. Parsey, and J.R. Arron et al. Lebrikizumab treatment in adults with asthma N Engl J Med 365 2011 1088 1098
14. M.M. Crane, C.M. Chang, M.G. Kobayashi, and P.F. Weller Incidence of myeloproliferative hypereosinophilic syndrome in the United States and an estimate of all hypereosinophilic syndrome incidence J Allergy Clin Immunol 126 2010 179 181
15. B.S. Bochner, W. Book, W.W. Busse, J.H. Butterfield, G.T. Furuta, and G.J. Gleich et al. Workshop report from the National Institutes of Health Taskforce on the Research Needs of Eosinophil-Associated Diseases (TREAD) J Allergy Clin Immunol 130 2012 587 596