Chromosome loss caused by DNA fragmentation induced in main nuclei and micronuclei of human lymphoblastoid cells treated with colcemid

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 762, Issue 1, 2014, Pages 10-16

  Yamamoto, Mika ^a,b   Wakata, Akihiro ^a   Aoki, Yoshinobu ^a   Miyamae, Yoichi ^a   Kodama, Seiji ^b  

^a ASTELLAS PHARMA INC   (Japan)

^b Osaka Prefecture University   (Japan)

Author keywords

Aneuploidy; Chromosome loss; DNA fragmentation; FISH; Micronucleus; TUNEL assay

Indexed keywords

DEMECOLCINE; DNA; MESYLIC ACID METHYL ESTER; PROTEIN P53;

ARTICLE; CELL NUCLEUS; CHROMOSOME 2; CHROMOSOME ANALYSIS; CHROMOSOME LOSS; CHROMOSOME PAINTING; CHROMOSOME SEGREGATION; CONTROLLED STUDY; CYTOKINESIS; DNA FRAGMENTATION; FLUORESCENCE IN SITU HYBRIDIZATION; GENE MUTATION; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL; MICRONUCLEUS; NICK END LABELING; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WILD TYPE;

ANEUPLOIDY; CHROMOSOME LOSS; DNA FRAGMENTATION; FISH; MICRONUCLEUS; TUNEL ASSAY;

ANEUPLOIDY; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 2; DEMECOLCINE; DNA FRAGMENTATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; IN SITU NICK-END LABELING; LYMPHOCYTES; METHYL METHANESULFONATE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MUTAGENS; NONDISJUNCTION, GENETIC; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84897419835     PISSN: 00275107     EISSN: 09218262     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2014.02.002     Document Type: Article

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