Intracellular distribution of the vitamin D receptor in the brain: Comparison with classic target tissues and redistribution with development

Neuroscience

Volumn 268, Issue , 2014, Pages 1-9

  Eyles, D W ^a,b   Liu, P Y ^a   Josh, P ^a   Cui, X ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b Queensland Centre for Mental Health Research   (Australia)

Author keywords

Development; Membrane vitamin D receptor; Nuclear vitamin D receptor; Rat

Indexed keywords

VITAMIN D RECEPTOR; CALCITRIOL RECEPTOR;

ADULT; ANIMAL TISSUE; ARTICLE; BRAIN; CELL MEMBRANE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSOL; DEVELOPMENT; EMBRYO; FEMALE; INTESTINE; KIDNEY; MATURATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; TARGET ORGAN; VITAMIN D DEFICIENCY; ANIMAL; ELECTROPHORESIS; GASTROINTESTINAL TRACT; GROWTH, DEVELOPMENT AND AGING; IMMUNOPRECIPITATION; INTRACELLULAR SPACE; METABOLISM; PROCEDURES; PROTEOMICS; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; BRAIN; CELL MEMBRANE; CELL NUCLEUS; ELECTROPHORESIS; GASTROINTESTINAL TRACT; IMMUNOPRECIPITATION; INTRACELLULAR SPACE; KIDNEY; PROTEOMICS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CALCITRIOL; VITAMIN D DEFICIENCY;

EID: 84897398240     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2014.02.042     Document Type: Article

References (40)

1. Almeras L., Eyles D., Benech P., Laffite D., Villard C., Patatian A., Boucraut J., Mackay-Sim A., McGrath J., Feron F. Developmental vitamin D deficiency alters brain protein expression in the adult rat: implications for neuropsychiatric disorders. Proteomics 2007, 7:769-780.
2. An C.I., Ganio E., Hagiwara N. Trip12, a HECT domain E3 ubiquitin ligase, targets Sox6 for proteasomal degradation and affects fiber type-specific gene expression in muscle cells. Skelet Muscle 2013, 3:11.
3. Barresi V., Grosso M., Barresi G. Immunohistochemical evidence of caveolin-1 expression in the human fetal and neonatal striated muscle and absence in the adult's. Appl Immunohistochem Mol Morphol 2008, 16:267-273.
4. Barsony J., Renyi I., McKoy W. Subcellular distribution of normal and mutant vitamin D receptors in living cells. Studies with a novel fluorescent ligand. J Biol Chem 1997, 272:5774-5782.
5. Bochar D.A., Wang L., Beniya H., Kinev A., Xue Y., Lane W.S., Wang W., Kashanchi F., Shiekhattar R. BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer. Cell 2000, 102:257-265.
6. Brewer L.D., Thibault V., Chen K.C., Langub M.C., Landfield P.W., Porter N.M. Vitamin D hormone confers neuroprotection in parallel with downregulation of L-type calcium channel expression in hippocampal neurons. J Neurosci 2001, 21:98-108.
7. Brewer L.D., Porter N.M., Kerr D.S., Landfield P.W., Thibault O. Chronic 1alpha,25-(OH)2 vitamin D3 treatment reduces Ca2+ -mediated hippocampal biomarkers of aging. Cell Calcium 2006, 40:277-286.
8. Burkert R., McGrath J., Eyles D. Vitamin D receptor expression in the embryonic rat brain. Neurosci Res Comm 2003, 33:63-71.
9. Cui X., McGrath J.J., Burne T.H., Mackay-Sim A., Eyles D.W. Maternal vitamin D depletion alters neurogenesis in the developing rat brain. Int J Dev Neurosci 2007, 25:227-232.
10. Cui X., Pelekanos M., Burne T.H., McGrath J.J., Eyles D.W. Maternal vitamin D deficiency alters the expression of genes involved in dopamine specification in the developing rat mesencephalon. Neurosci Lett 2010, 486:220-223.
11. Cui X., Pelekanos M., Liu P.Y., Burne T.H., McGrath J.J., Eyles D.W. The vitamin D receptor in dopamine neurons; its presence in human substantia nigra and its ontogenesis in rat midbrain. Neuroscience 2013, 97:907-908.
12. Deng C., Ueda E., Chen K.E., Bula C., Norman A.W., Luben R.A., Walker A.M. Prolactin blocks nuclear translocation of VDR by regulating its interaction with BRCA1 in osteosarcoma cells. Mol Endocrinol 2009, 23:226-236.
13. Eyles D., Brown J., Mackay-Sim A., McGrath J., Feron F. Vitamin D3 and brain development. Neuroscience 2003, 118:641-653.
14. Eyles D.W., Smith S., Kinobe R., Hewison M., McGrath J.J. Distribution of the vitamin D receptor and 1 alpha-hydroxylase in human brain. J Chem Neuroanat 2005, 29:21-30.
15. Eyles D., Almeras L., Benech P., Patatian A., Mackay-Sim A., McGrath J., Feron F. Developmental vitamin D deficiency alters the expression of genes encoding mitochondrial, cytoskeletal and synaptic proteins in the adult rat brain. J Steroid Biochem Mol Biol 2007, 103:538-545.
16. Eyles D.W., Burne T.H., McGrath J.J. Vitamin D, effects on brain development, adult brain function and the links between low levels of vitamin D and neuropsychiatric disease. Front Neuroendocrinol 2012, 34:47-64.
17. Fujiki R., Kim M.S., Sasaki Y., Yoshimura K., Kitagawa H., Kato S. Ligand-induced transrepression by VDR through association of WSTF with acetylated histones. EMBO J 2005, 24:3881-3894.
18. Glaser S.D., Veenstra T.D., Jirikowski G.F., Prufer K. Distribution of 1,25-dihydroxyvitamin D3 receptor immunoreactivity in the rat olfactory system. Cell Mol Neurobiol 1999, 19:613-624.
19. Gofflot F., Chartoire N., Vasseur L., Heikkinen S., Dembele D., Le Merrer J., Auwerx J. Systematic gene expression mapping clusters nuclear receptors according to their function in the brain. Cell 2007, 131:405-418.
20. Guillemin I., Becker M., Ociepka K., Friauf E., Nothwang H.G. A subcellular prefractionation protocol for minute amounts of mammalian cell cultures and tissue. Proteomics 2005, 5:35-45.
21. Holick M.F. Vitamin D deficiency. N Engl J Med 2007, 357:266-281.
22. Huang H., Wei H., Zhang X., Chen K., Li Y., Qu P., Zhang X., Chen J., Liu Y., Yang L., Li T. Changes in the expression and subcellular localization of RARalpha in the rat hippocampus during postnatal development. Brain Res 2008, 1227:26-33.
23. Huhtakangas J.A., Olivera C.J., Bishop J.E., Zanello L.P., Norman A.W. The vitamin D receptor is present in caveolae-enriched plasma membranes and binds 1 alpha,25(OH)2-vitamin D3 in vivo and in vitro. Mol Endocrinol 2004, 18:2660-2671.
24. Ko P., Burkert R., McGrath J., Eyles D. Maternal vitamin D3 deprivation and the regulation of apoptosis and cell cycle during rat brain development. Brain Res Dev Brain Res 2004, 153:61-68.
25. Mehta R.G., Mehta R.R. Vitamin D and cancer. J Nutr Biochem 2002, 13:252-264.
26. Nemere I., Norman A.W. 1,25-Dihydroxyvitamin D3-mediated vesicular transport of calcium in intestine: time-course studies. Endocrinology 1988, 122:2962-2969.
27. Nemere I., Dormanen M.C., Hammond M.W., Okamura W.H., Norman A.W. Identification of a specific binding protein for 1 alpha,25-dihydroxyvitamin D3 in basal-lateral membranes of chick intestinal epithelium and relationship to transcaltachia. J Biol Chem 1994, 269:23750-23756.
28. Norman A.W., Olivera C.J., Barreto Silva F.R., Bishop J.E. A specific binding protein/receptor for 1alpha,25-dihydroxyvitamin D(3) is present in an intestinal caveolae membrane fraction. Biochem Biophys Res Commun 2002, 298:414-419.
29. Orme R.P., Bhangal M.S., Fricker R.A. Calcitriol imparts neuroprotection in vitro to midbrain dopaminergic neurons by upregulating GDNF expression. PLoS ONE 2013, 8:e62040.
30. Peleg S., Nguyen C.V. The importance of nuclear import in protection of the vitamin D receptor from polyubiquitination and proteasome-mediated degradation. J Cell Biochem 2010, 110:926-934.
31. Prufer K., Veenstra T.D., Jirikowski G.F., Kumar R. Distribution of 1,25-dihydroxyvitamin D3 receptor immunoreactivity in the rat brain and spinal cord. J Chem Neuroanat 1999, 16:135-145.
32. Stumpf W.E., O'Brien L.P. 1,25 (OH)2 vitamin D3 sites of action in the brain. An autoradiographic study. Histochemistry 1987, 87:393-406.
33. Swamy N., Mohr S.C., Xu W., Ray R. Vitamin D receptor interacts with DnaK/heat shock protein 70: identification of DnaK interaction site on vitamin D receptor. Arch Biochem Biophys 1999, 363:219-226.
34. van den Bemd G.C., Pols H.A., Birkenhager J.C., van Leeuwen J.P. Conformational change and enhanced stabilization of the vitamin D receptor by the 1,25-dihydroxyvitamin D3 analog KH1060. Proc Natl Acad Sci U S A 1996, 93:10685-10690.
35. Veenstra T.D., Prufer K., Koenigsberger C., Brimijoin S.W., Grande J.P., Kumar R. 1,25-Dihydroxyvitamin D3 receptors in the central nervous system of the rat embryo. Brain Res 1998, 804:193-205.
36. Wang Y., DeLuca H.F. Is the vitamin d receptor found in muscle?. Endocrinology 2011, 152:354-363.
37. Wang Y., Becklund B.R., DeLuca H.F. Identification of a highly specific and versatile vitamin D receptor antibody. Arch Biochem Biophys 2010, 494:166-177.
38. Wang Y., Zhu J., DeLuca H.F. Where is the vitamin D receptor?. Arch Biochem Biophys 2012, 523:123-133.
39. Wiese R.J., Uhland-Smith A., Ross T.K., Prahl J.M., DeLuca H.F. Up-regulation of the vitamin D receptor in response to 1,25-dihydroxyvitamin D3 results from ligand-induced stabilization. J Biol Chem 1992, 267:20082-20086.
40. Zou J., Landy H., Feun L., Xu R., Lampidis T., Wu C.J., Furst A.J., Savaraj N. Correlation of a unique 220-kDa protein with vitamin D sensitivity in glioma cells. Biochem Pharmacol 2000, 60:1361-1365.