Novel Pancreas Organogenesis Markers Refine the Pancreatic Differentiation Roadmap of Embryonic Stem cells

Stem Cell Reviews and Reports

Volumn 10, Issue 2, 2014, Pages 269-279

  De Angelis, Maria Teresa ^a   Russo, Filomena ^a   D'Angelo, Fulvio ^a   Federico, Antonella ^b   Gemei, Marica ^b   Del Vecchio, Luigi ^b   Ceccarelli, Michele ^a,c   De Felice, Mario ^a,b   Falco, Geppino ^a,c  

^a Grande Ospedale Metropolitano   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c UNIVERSITY OF SANNIO   (Italy)

Author keywords

Bud; Embryonic stem cells; Laser microdissection; Pancreas; Progenitor cells; Specification

Indexed keywords

BEX1 PROTEIN, MOUSE; BIOLOGICAL MARKER; GLYCOPROTEIN; HOMEODOMAIN PROTEIN; NEPHROCAN PROTEIN, MOUSE; NERVE PROTEIN; PANCREATIC AND DUODENAL HOMEOBOX 1 PROTEIN; TRANSACTIVATOR PROTEIN;

ANIMAL; ANTIBODY SPECIFICITY; CELL DIFFERENTIATION; CYTOLOGY; EMBRYOLOGY; EMBRYONIC STEM CELL; GENE EXPRESSION; GENE EXPRESSION REGULATION; METABOLISM; MOUSE; ORGANOGENESIS; PANCREAS; PHYSIOLOGY;

ANIMALS; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; EMBRYONIC STEM CELLS; GENE EXPRESSION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLYCOPROTEINS; HOMEODOMAIN PROTEINS; MICE; NERVE TISSUE PROTEINS; ORGAN SPECIFICITY; ORGANOGENESIS; PANCREAS; TRANS-ACTIVATORS;

EID: 84897379259     PISSN: 15508943     EISSN: 15586804     Source Type: Journal    
DOI: 10.1007/s12015-013-9489-5     Document Type: Article

References (37)

1. Carter, M. G., Stagg, C. A., Falco, G., et al. (2008). An in situ hybridization-based screen for heterogeneously expressed genes in mouse ES cells. Gene Expression Patterns, 8(3), 181-198.
2. Zhu, Z., & Huangfu, D. (2013). Human pluripotent stem cells: an emerging model in developmental biology. Development, 140(4), 705-717.
3. Bhushan, A., Itoh, N., Kato, S., et al. (2001). Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis. Development, 128, 5109-5117.
4. Hebrok, M., Kim, S. K., St Jacques, B., McMahon, A. P., & Melton, D. A. (2000). Regulation of pancreas development by hedgehog signaling. Development, 127, 4905-4913.
5. Martin, M., Gallego-Llamas, J., Ribes, V., et al. (2005). Dorsal pancreas agenesis in retinoic acid-deficient Raldh2 mutant mice. Developmental Biology, 284, 399-411.
6. Molotkov, A., Molotkova, N., & Duester, G. (2005). Retinoic acid generated by Raldh2 in mesoderm is required for mouse dorsal endodermal pancreas development. Developmental Dynamics, 232, 950-957.
7. Yang, Y. P., & Wright, C. (2009). Chemicals turn human embryonic stem cells towards beta cells. Nature Chemical Biology, 5, 195-196.
8. D'Amour, K. A., Bang, A. G., Eliazer, S., et al. (2006). Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nature Biotechnology, 24, 1392-1401.
9. Kroon, E., Martinson, L. A., Kadoya, K., et al. (2008). Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo. Nature Biotechnology, 26, 443-452.
10. Gu, G., Dubauskaite, J., & Melton, D. A. (2002). Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development, 129, 2447-2457.
11. Irizarry, R. A., Hobbs, B., Collin, F., et al. (2003). Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics, 4(2), 249-264.
12. Livak, K. J., & Schmittge, T. D. (2001). Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCt. Methods, 25, 402-408.
13. Little, M. H., Brennan, J., Georgas, K., et al. (2007). A high-resolution anatomical ontologyof the developing murine genitourinary tract. Gene Expression Patterns, 7, 680-699.
14. Stryke, D., Kawamoto, M., Huang, C. C., et al. (2003). BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Nucleic Acids Research, 31(1), 278-281.
15. Poot, M., & Arttamangkul, S. (1997). Verapamil inhibition of enzymatic product efflux leads to improved detection of beta-galactosidase activity in lacZ transfected cells. Cytometry, 28, 36-41.
16. Yamanaka, S., Zhang, X. Y., Maeda, M., et al. (2000). Essential role of NAT1/p97/DAP5 in embryonic differentiation and the retinoic acid pathway. EMBO Journal, 19, 5533-5541.
17. Pictet, R. L., Clark, W. R., Williams, R. H., & Rutter, W. J. (1972). An ultrastructural analysis of the developing embryonic pancreas. Developmental Biology, 29, 436-467.
18. Herrera, P. L. (2000). Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages. Development, 127, 2317-2322.
19. Kesavan, G., Sand, F. W., Greiner, T. U., et al. (2009). Cdc42 mediated tubulogenesis controls cell specification. Cell, 139, 791-801.
20. Villasenor, A., Chong, D. C., Henkemeyer, M., & Cleaver, O. (2010). Epithelial dynamics of pancreatic branching morphogenesis. Development, 137, 4295-4305.
21. Alvarez, E., Zhou, W., Witta, S. E., & Freed, C. R. (2005). Characterization of the Bex gene family in humans, mice, and rats. Gene, 357(1), 18-28.
22. Mochida, Y., Parisuthiman, D., Kaku, M., et al. (2006). Nephrocan, a novel member of the small leucine-rich repeat protein family, is an inhibitor of transforming growth factor-beta signaling. Journal of Biological Chemistry, 281(47), 36044-36051.
23. Li, X., Udager, A. M., Hu, C., Qiao, X. T., Richards, N., & Gumucio, D. L. (2009). Dynamic patterning at the pylorus: formation of an epithelial intestine-stomach boundary in late fetal life. Developmental Dynamics, 238(12), 3205-3217.
24. Ogaki, S., Harada, S., Shiraki, N., Kume, K., & Kume, S. (2011). An expression profile analysis of ES cell-derived definitive endodermal cells and Pdx1-expressing cells. BMC Developmental Biology, 11, 13.
25. Ivanov, I., Lo, K. C., Hawthorn, L., Cowell, J. K., & Ionov, Y. (2007). Identifying candidate colon cancer tumor suppressor genes using inhibition of nonsense-mediated mRNA decay in colon cancer cells. Oncogene, 26, 2873-2884.
26. Suazo, J., Pardo, R., Castillo, S., et al. (2013). Family-based association study between SLC2A1, HK1, and LEPR polymorphisms with myelomeningocele in Chile. Reproductive Sciences. doi: 10. 1177/1933719113477489.
27. Taupin, D., & Podolsky, D. K. (2003). Trefoil factors: initiators of mucosal healing. Nature Reviews Molecular Cell Biology, 4, 721-732.
28. Hernández, C., Santamatilde, E., McCreath, K. J., et al. (2009). Induction of trefoil factor (TFF)1, TFF2 and TFF3 by hypoxia is mediated by hypoxia inducible factor-1: implications for gastric mucosal healing. British Journal of Pharmacology, 156, 262-272.
29. Fueger, P. T., Schisler, J. C., et al. (2008). Trefoil factor 3 stimulates human and rodent pancreatic islet β-cell replication with retention of function. Molecular Endocrinology, 22(5), 1251-1259.
30. Fagman, H., Amendola, E., Parrillo, L., et al. (2011). Gene expression profiling at early organogenesis reveals both common and diverse mechanisms in foregut patterning. Developmental Biology, 359(2), 163-175.
31. Sui, J., Mehta, M., Shi, B., Morahan, G., & Jiang, F.-X. (2012). Directed differentiation of embryonic stem cells allows exploration of novel transcription factor genes for pancreas development. Stem Cell Reviews, 8, 803-812.
32. Hu, J., Xie, C., Ma, H., Yang, B., Ma, P. X., & Chen, Y. E. (2012). Construction of vascular tissues with macro-porous nano-fibrous scaffolds and smooth muscle cells enriched from differentiated embryonic stem cells. PLoS One, 7(4), e35580.
33. Decker, K., Goldman, D. C., Grasch, C. L., & Sussel, L. (2006). Gata6 is an important regulator of mouse pancreas development. Developmental Biology, 298, 415-429.
34. Watt, A. J., Zhao, R., Li, J., & Duncan, S. A. (2007). Development of the mammalian liver and ventral pancreas is dependent on GATA4. BMC Developmental Biology, 7, 37.
35. Bonal, C., & Herrera, L. P. (2008). Genes controlling pancreas ontogeny. International Journal of Developmental Biology, 52, 823-835.
36. Richardson, C. C., Hussain, K., Jones, P. M., et al. (2007). Low levels of glucose transporters and K+ ATP channels in human pancreatic beta cells early in development. Diabetologia, 50(5), 1000-1005.
37. Higuchi, Y., Shiraki, N., & Kume, S. (2011). In vitro models of pancreatic differentiation using embryonic stem or induced pluripotent stem cells. Congenit Anom (Kyoto), 51(1), 21-25.