Overexpression of autotaxin, a lysophosphatidic acid-producing enzyme, enhances cardia bifida induced by hypo-sphingosine-1-phosphate signaling in zebrafish embryo

Journal of Biochemistry

Volumn 155, Issue 4, 2014, Pages 235-241

  Nakanaga, Keita ^a   Hama, Kotaro ^a   Kano, Kuniyuki ^a   Sato, Takanao ^a   Yukiura, Hiroshi ^a   Inoue, Asuka ^a,b   Saigusa, Daisuke ^a   Tokuyama, Hidetoshi ^a   Tomioka, Yoshihisa ^a   Nishina, Hiroshi ^c   Kawahara, Atsuo ^d   Aoki, Junken ^a,b  

^a TOHOKU UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^d RIKEN Center for Biosystems Dynamics Research   (Japan)

Author keywords

autotoxin; cardia bifida; lysophosphatidic acid; sphingosine 1 phosphate; zebrafish

Indexed keywords

AUTOTAXIN; LYSOPHOSPHATIDIC ACID; MESSENGER RNA; MORPHOLINO OLIGONUCLEOTIDE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE 1 PHOSPHATE TRANSPORTER; UNCLASSIFIED DRUG; 3-(4-(4-((1-(2-CHLOROPHENYL)ETHOXY)CARBONYL AMINO)-3-METHYL-5-ISOXAZOLYL) BENZYLSULFANYL) PROPANOIC ACID; ALKYLGLYCEROPHOSPHOETHANOLAMINE PHOSPHODIESTERASE; ISOXAZOLE DERIVATIVE; LYSOPHOSPHATIDIC ACID RECEPTOR; LYSOPHOSPHOLIPID; PHOSPHODIESTERASE; PROPIONIC ACID DERIVATIVE; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE;

ANIMAL EXPERIMENT; ARTICLE; CARDIA BIFIDA; CATALYSIS; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; GENE OVEREXPRESSION; HEART DISEASE; IN VIVO STUDY; NONHUMAN; PHENOTYPE; ZEBRA FISH; AGONISTS; ANALOGS AND DERIVATIVES; ANIMAL; ANIMAL EMBRYO; BIOSYNTHESIS; CONGENITAL HEART MALFORMATION; DRUG EFFECTS; EMBRYOLOGY; ENZYMOLOGY; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; DOWN-REGULATION; EMBRYO, NONMAMMALIAN; HEART DEFECTS, CONGENITAL; HEK293 CELLS; HUMANS; ISOXAZOLES; LYSOPHOSPHOLIPIDS; PHENOTYPE; PHOSPHORIC DIESTER HYDROLASES; PROPIONATES; RECEPTORS, LYSOPHOSPHATIDIC ACID; RNA, MESSENGER; SIGNAL TRANSDUCTION; SPHINGOSINE; ZEBRAFISH;

EID: 84897376191     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvt114     Document Type: Article

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