Platelets support extracellular sialylation by supplying the sugar donor substrate

Journal of Biological Chemistry

Volumn 289, Issue 13, 2014, Pages 8742-8748

  Lee, Melissa M ^a   Nasirikenari, Mehrab ^a   Manhardt, Charles T ^a   Ashline, David J ^b   Hanneman, Andrew J ^b   Reinhold, Vernon N ^b   Lau, Joseph T Y ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

^b UNIVERSITY OF NEW HAMPSHIRE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD SUBSTITUTES; CARBOXYLIC ACIDS; CELL MEMBRANES; ENZYMES; ESTERIFICATION; GLYCOSYLATION; PHYSIOLOGY; PLATELETS;

ACTIVATED PLATELETS; ANTI-INFLAMMATORIES; BIOACTIVE MOLECULES; DONOR SUBSTRATES; GLYCOSYLTRANSFERASE ACTIVITY; GLYCOSYLTRANSFERASES; HEMATOPOIETIC PROGENITOR CELLS; SOLUBLE SUBSTRATES;

SUBSTRATES;

BETA GALACTOSIDASE ALPHA2,6 SIALYLTRANSFERASE; CYTIDINE PHOSPHATE; GLYCOSYLTRANSFERASE; SIALIC ACID; SUGAR; THROMBIN; UNCLASSIFIED DRUG; BETA-D-GALACTOSIDE ALPHA 2-6-SIALYLTRANSFERASE; N ACETYLNEURAMINIC ACID; POLYSACCHARIDE; SIALYLTRANSFERASE;

ANIMAL CELL; ARTICLE; CATALYSIS; CELL PH; CELL SURFACE; CONTROLLED STUDY; ENZYME GLYCOSYLATION; EXTRACELLULAR SPACE; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOUSE; NONHUMAN; PLATELET MICROPARTICLE; PRIORITY JOURNAL; SIALYLATION; THROMBOCYTE; THROMBOCYTE ACTIVATION; ANIMAL; CYTOLOGY; ENZYMOLOGY; METABOLISM;

ANIMALS; BLOOD PLATELETS; EXTRACELLULAR SPACE; MICE; N-ACETYLNEURAMINIC ACID; POLYSACCHARIDES; SIALYLTRANSFERASES;

EID: 84897370502     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.C113.546713     Document Type: Article

References (35)

1. Kaplan, H. A., Woloski, B. M., Hellman, M., and Jamieson, J. C. (1983) Studies on the effect of inflammation on rat liver and serum sialyltransferase: evidence that inflammation causes release of Galß1→4GlcNAc α2→6 sialyltransferase from liver. J. Biol. Chem. 258, 11505-11509 (Pubitemid 13019298)
2. Dalziel, M., Lemaire, S., Ewing, J., Kobayashi, L., and Lau, J. T. Y. (1999) Hepatic acute phase induction of murine β-galactoside α2,6-sialyltransferase (ST6Gal I) is IL-6 dependent and mediated by elevation of exon H-containing class of transcripts. Glycobiology 9, 1003-1008 (Pubitemid 29473957)
3. Jamieson, J. C., Lammers, G., Janzen, R., and Woloski, B. M. (1987) The acute phase response to inflammation: the role of monokines in changes in liver glycoproteins and enzymes of glycoprotein metabolism. Comp. Biochem. Physiol. B. 87, 11-15
4. Bernacki, R. J., and Kim, U. (1977) Concomitant elevations in serum sialytransferase activity and sialic acid content in rats with metastasizing mammary tumors. Science 195, 577-580 (Pubitemid 8030045)
5. Nasirikenari, M., Chandrasekaran, E. V., Matta, K. L., Segal, B. H., Bogner, P. N., Lugade, A. A., Thanavala, Y., Lee, J. J., and Lau, J. T. (2010) Altered eosinophil profile in mice with ST6Gal-1 deficiency: an additional role for ST6Gal-1 generated by the P1 promoter in regulating allergic inflammation. J. Leukoc. Biol. 87, 457-466
6. Sillanaukee, P., Pönniö, M., and Seppä, K. (1999) Sialic acid: new potential marker of alcohol abuse. Alcohol Clin Exp Res. 23, 1039-1043 (Pubitemid 29283499)
7. Gong, M., Garige, M., Hirsch, K., and Lakshman, M. R. (2007) Liver Galß1,4GlcNAc α2,6-sialyltransferase is down-regulated in human alcoholics: possible cause for the appearance of asialoconjugates. Metabolism 56, 1241-1247 (Pubitemid 47223264)
8. Ip, C., and Dao, T. (1978) Alterations in serum glycosyltransferases and 5′-nucleotidase in breast cancer patients. Cancer Res. 38, 723-728 (Pubitemid 8319548)
9. Kim, Y. S., Perdomo, J., Whitehead, J. S., and Curtis, K. J. (1972) Glycosyltransferases in human blood: II. Study of serum galactosyltransferase and N-acetylgalactosaminyltransferase in patients with liver diseases. J. Clin. Invest. 51, 2033-2039
10. Poon, T. C., Chiu, C. H., Lai, P. B., Mok, T. S., Zee, B., Chan, A. T., Sung, J. J., and Johnson, P. J. (2005) Correlation and prognostic significance of β-galactoside α-2,6-sialyltransferase and serum monosialylated α-fetoprotein in hepatocellular carcinoma. World J Gastroenterol. 11, 6701-6706 (Pubitemid 43072715)
11. Weiser, M. M., Podolsky, D. K., and Iselbacher, K. J. (1976) Cancer-associated isoenzyme of serum galactosyltransferase. Proc. Natl. Acad. Sci. U.S.A. 73, 1319-1322
12. Gessner, P., Riedl, S., Quentmaier, A., and Kemmner, W. (1993) Enhanced activity of CMP-neuAc:Galß1-4GlcNAc:α2,6-sialyltransferase in metastasizing human colorectal tumor tissue and serum of tumor patients. Cancer Lett. 75, 143-149 (Pubitemid 24025630)
13. Wang, X. C., O'Hanlon, T. P., and Lau, J. Y. (1989) Regulation of β-galactoside α2,6-sialyltransferase gene expression by dexamethasone. J. Biol. Chem. 264, 1854-1859 (Pubitemid 19051034)
14. Hoflack, B., Cacan, R., Montreuil, J., and Verbert, A. (1979) Detection of ectosialyltransferase activity using whole cells. Biochim. Biophys. Acta 568, 348-356
15. Nasirikenari, M., Veillon, L., Collins, C. C., Azadi, P., and Lau, J. T. Y. (2014) Remodeling of marrow hematopoietic stem and progenitor cells by non-self ST6Gal-1 sialytransferase. J. Biol. Chem. 289, 7178-7189
16. Wandall, H. H., Rumjantseva, V., Sørensen, A. L. T., Patel-Hett, S., Josefsson, E. C., Bennett, E. P., Italiano, J. E., Jr., Clausen, H., Hartwig, J. H., and Hoffmeister, K. M. (2012) The origin and function of platelet glycosyltransferases. Blood 120, 626-635
17. Martin, L. T., Marth, J. D., Varki, A., and Varki, N. M. (2002) Genetically altered mice with different sialyltransferase deficiencies show tissue-specific alterations in sialylation and sialic acid 9-O-acetylation. J. Biol. Chem. 277, 32930-32938 (Pubitemid 34987555)
18. Nasirikenari, M., Segal, B. H., Ostberg, J. R., Urbasic, A., and Lau, J. T. (2006) Altered granulopoietic profile and exaggerated acute neutrophilic inflammation in mice with targeted deficiency in the sialyltransferase ST6Gal I. Blood 108, 3397-3405
19. Hoffmeister, K. M., Felbinger, T. W., Falet, H., Denis, C. V., Bergmeier, W., Mayadas, T. N., von Andrian, U. H., Wagner, D. D., Stossel, T. P., and Hartwig, J. H. (2003) The clearance mechanism of chilled blood platelets. Cell 112, 87-97 (Pubitemid 36106421)
20. Toma, V., Zuber, C., Winter, H. C., Goldstein, I. J., and Roth, J. (2001) Application of a lectin from the mushroom Polysporus squamosus for the histochemical detection of the NeuAcα2,6Galß1,4Glc/GlcNAc sequence of N-linked oligosaccharides: a comparison with the Sambucus nigra lectin. Histochem Cell Biol. 116, 183-193 (Pubitemid 32778648)
21. Shibuya, N., Goldstein, I. J., Broekaert, W. F., Nsimba-Lubaki, M., Peeters, B., and Peumans, W. J. (1987) The elderberry (Sambucus nigra L.) bark lectin recognizes the Neu5Ac(α2-6)Gal/GalNAc sequence. J. Biol. Chem. 262, 1596-1601
22. Appenheimer, M. M., Huang, R.-Y., Chandrasekaran, E. V., Dalziel, M., Hu, Y. P., Soloway, P. D., Wuensch, S. A., Matta, K. L., and Lau, J. T. Y. (2003) Biologic contribution of P1 promoter-mediated expression of ST6Gal I sialyltransferase. Glycobiology 13, 591-600 (Pubitemid 36939575)
23. Ujita, M., McAuliffe, J., Schwientek, T., Almeida, R., Hindsgaul, O., Clausen, H., and Fukuda, M. (1998) Synthesis of poly-N-acetyllactosamine in core 2 branched O-glycans: the requirement of novel β-1,4-galactosyltransferase IV and β-1,3-N-acetylglucosaminyltransferase. J. Biol. Chem. 273, 34843-34849
24. Kang, P., Mechref, Y., Klouckova, I., and Novotny, M. V. (2005) Solid-phase permethylation of glycans for mass spectrometric analysis. Rapid Commun. Mass Spectrom. 19, 3421-3428 (Pubitemid 41691916)
25. Ashline, D. J., Hanneman, A. J., Zhang, H., and Reinhold, V. N. (2014) Structural documentation of glycan epitopes: Sequential mass spectrometry and spectral matching. J. Am. Soc. Mass. Spectrom. 25, 444-453
26. Italiano, J. E., Jr., Mairuhu, A. T. A., and Flaumenhaft, R. (2010) Clinical relevance of microparticles from platelets and megakaryocytes. Curr Opin Hematol. 17, 578-584
27. Semple, J. W., Italiano, J. E., Jr., and Freedman, J. (2011) Platelets and the immune continuum. Nat. Rev. Immunol. 11, 264-274
28. Coppinger, J. A., Cagney, G., Toomey, S., Kislinger, T., Belton, O., McRedmond, J. P., Cahill, D. J., Emili, A., Fitzgerald, D. J., and Maguire, P. B. (2004) Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions. Blood 103, 2096-2104 (Pubitemid 38326225)
29. Huo, Y., and Ley, K. F. (2004) Role of platelets in the development of atherosclerosis. Trends Cardiovasc. Med. 14, 18-22 (Pubitemid 38068207)
30. Secor, D., Li, F., Ellis, C. G., Sharpe, M. D., Gross, P. L., Wilson, J. X., and Tyml, K. (2010) Impaired microvascular perfusion in sepsis requires activated coagulation and P-selectin-mediated platelet adhesion in capillaries. Intensive Care Med. 36, 1928-1934
31. Ogura, H., Kawasaki, T., Tanaka, H., Koh, T., Tanaka, R., Ozeki, Y., Hosotsubo, H., Kuwagata, Y., Shimazu, T., and Sugimoto, H. (2001) Activated platelets enhance microparticle formation and platelet-leukocyte interaction in severe trauma and sepsis. J Trauma. 50, 801-809 (Pubitemid 32499602)
32. Schmitt-Sody, M., Metz, P., Gottschalk, O., Birkenmaier, C., Zysk, S., Veihelmann, A., and Jansson, V. (2007) Platelet P-selectin is significantly involved in leukocyte-endothelial cell interaction in murine antigen-induced arthritis. Platelets 18, 365-372 (Pubitemid 47123839)
33. Knijff-Dutmer, E. A. J., Koerts, J., Nieuwland, R., Kalsbeek-Batenburg, E. M., and Van de Laar, M. A. F. J. (2002) Elevated levels of platelet microparticles are associated with disease activity in rheumatoid arthritis. Arthritis Rheum. 46, 1498-1503 (Pubitemid 34620195)
34. Gay, L. J., and Felding-Habermann, B. (2011) Contribution of platelets to tumour metastasis. Nat. Rev. Cancer 11, 123-134
35. Bambace, N. M., and Holmes, C. E. (2011) The platelet contribution to cancer progression. J. Thromb. Haemost. 9, 237-249