Inhibitory effect of the selective serotonin 5-HT3 receptor antagonist ramosetron on duodenal acidification-induced gastric hypersensitivity in rats

European Journal of Pharmacology

Volumn 731, Issue 1, 2014, Pages 88-92

  Nakata Fukuda, Mari ^a,b   Hirata, Takuya ^a   Keto, Yoshihiro ^a   Yamano, Mayumi ^a   Yokoyama, Toshihide ^a   Uchiyama, Yasuo ^b  

^a ASTELLAS PHARMA INC   (Japan)

^b JUNTENDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Duodenal acidification; Gastric hypersensitivity; Ramosetron; Rat

Indexed keywords

GASTROINTESTINAL AGENT; LOPERAMIDE; RAMOSETRON; SEROTONIN 3 RECEPTOR; TIQUIZIUM BROMIDE; TRIMEBUTINE; UNCLASSIFIED DRUG; 1-(3-CHLOROPHENYL)BIGUANIDE; BENZIMIDAZOLE DERIVATIVE; BIGUANIDE DERIVATIVE; QUINOLIZINE DERIVATIVE; SEROTONIN 3 ANTAGONIST; THIATON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; EXPERIMENTAL MODEL; GASTRIC HYPERSENSITIVITY; MALE; MEAN ARTERIAL PRESSURE; NOCICEPTION; NONHUMAN; PRESSOR RESPONSE; PRIORITY JOURNAL; RAT; STOMACH DISEASE; STOMACH DISTENSION; ANIMAL; CHEMISTRY; DRUG EFFECTS; DUODENUM; IRRITABLE BOWEL SYNDROME; PATHOPHYSIOLOGY; PH; SPRAGUE DAWLEY RAT; STOMACH;

ANIMALS; BENZIMIDAZOLES; BIGUANIDES; DUODENUM; HYDROGEN-ION CONCENTRATION; IRRITABLE BOWEL SYNDROME; MALE; NOCICEPTION; QUINOLIZINES; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN 5-HT3 RECEPTOR ANTAGONISTS; STOMACH;

EID: 84897360019     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.02.040     Document Type: Article

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