Mangromicins A and B: Structure and antitrypanosomal activity of two new cyclopentadecane compounds from Lechevalieria aerocolonigenes K10-0216

Journal of Antibiotics

Volumn 67, Issue 3, 2014, Pages 253-260

  Nakashima, Takuji ^a   Iwatsuki, Masato ^a   Ochiai, Junya ^a   Kamiya, Yoshiyuki ^a   Nagai, Kenichiro ^a   Matsumoto, Atsuko ^a   Ishiyama, Aki ^a   Otoguro, Kazuhiko ^a   Shiomi, Kazuro ^a   Takahashi, Yoko ^a   Omura, Satoshi ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

Antitrypanosomal activity; Lechevalieria aerocolonigenes; Mangromicins; Mangrove sediment; Physicochemical screening

Indexed keywords

5,6 DIHYDRO 4 HYDROXY 2 PYRONE; ANTITRYPANOSOMAL AGENT; CYCLODECANE DERIVATIVE; EFLORNITHINE; MANGROMICIN A; MANGROMICIN B; RNA 16S; SILICA GEL; SURAMIN; TETRAHYDROFURAN; UNCLASSIFIED DRUG;

ACTINOBACTERIA; ANTIPROTOZOAL ACTIVITY; ARTICLE; BROTH DILUTION; CARBON NUCLEAR MAGNETIC RESONANCE; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG PURIFICATION; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; ESTERIFICATION; FETUS; FETUS LUNG; FIBROBLAST; GENE SEQUENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; LECHEVALIERIA AEROCOLONIGENES K10 0216; LIQUID CHROMATOGRAPHY; MANGROVE; MASS SPECTROMETRY; MORPHOLOGICAL TRAIT; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENETIC TREE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; TRYPANOSOMA BRUCEI; X RAY CRYSTALLOGRAPHY;

ACTINOMYCETALES; CHROMATOGRAPHY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRYSTALLOGRAPHY, X-RAY; FIBROBLASTS; HUMANS; INHIBITORY CONCENTRATION 50; LUNG; MACROLIDES; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; SILICA GEL; TOXICITY TESTS; TRYPANOCIDAL AGENTS;

EID: 84897130454     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2013.129     Document Type: Article

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