Manganese regulates caspase-3 gene promoter activity by inducing Sp1 phosphorylation in PC12 cells

Toxicology

Volumn 302, Issue 2-3, 2012, Pages 292-298

  Uchida, Atsuhiro ^a   Oh Hashi, Kentaro ^a   Kiuchi, Kazutoshi ^a   Hirata, Yoko ^a  

^a GIFU UNIVERSITY   (Japan)

Author keywords

Caspase 3; Manganese; Phosphorylation; Sp1

Indexed keywords

CASPASE 3; MANGANESE; MESSENGER RNA; TRANSCRIPTION FACTOR SP1; CASP3 PROTEIN, RAT; DOPAMINE;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; DNA BINDING; DNA FLANKING REGION; ENZYME ACTIVITY; GEL MOBILITY SHIFT ASSAY; GENE DELETION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; RAT; UPREGULATION; ANIMAL; APOPTOSIS; DNA FRAGMENTATION; DRUG EFFECT; GENETICS; METABOLISM; PC12 CELL; PHOSPHORYLATION;

RATTUS;

ANIMALS; APOPTOSIS; BINDING SITES; CASPASE 3; DNA FRAGMENTATION; DOPAMINE; MANGANESE; PC12 CELLS; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; RATS; SP1 TRANSCRIPTION FACTOR;

EID: 84897123485     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2012.08.011     Document Type: Article

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