Cytokine and chemokine levels in patients infected with the novel avian influenza a (H7N9) virus in China

Journal of Infectious Diseases

Volumn 208, Issue 12, 2013, Pages 1962-1967

  Chi, Ying ^a   Zhu, Yefei ^a   Wen, Tian ^a   Cui, Lunbiao ^a   Ge, Yiyue ^a   Jiao, Yongjun ^a   Wu, Tao ^a   Ge, Aihua ^a   Ji, Hong ^a   Xu, Ke ^a   Bao, Changjun ^a   Zhu, Zheng ^a   Qi, Xian ^a   Wu, Bin ^a   Shi, Zhiyang ^a   Tang, Fenyang ^b   Xing, Zheng ^a   Zhou, Minghao ^a  

^a JIANGSU PROVINCIAL CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^b NANJING UNIVERSITY   (China)

Author keywords

Chemokine; Cytokine; H7N9 avian influenza

Indexed keywords

CHEMOKINE; CYTOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 6;

ADULT; ARTICLE; AVIAN INFLUENZA; AVIAN INFLUENZA A (H7N9); AVIAN INFLUENZA A (H7N9) VIRUS; AVIAN INFLUENZA VIRUS; CHINA; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RESPONSE; DISEASE COURSE; DISEASE SEVERITY; FEMALE; HUMAN; HUMAN CELL; IMMUNOASSAY; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN INDUCTION; STATISTICAL ANALYSIS; TH1 CELL; TH17 CELL; ADOLESCENT; AGED; BLOOD; IMMUNOLOGY; INFLUENZA VIRUS A H7N9; INFLUENZA, HUMAN; MIDDLE AGED; VIROLOGY; H7N9 AVIAN INFLUENZA; INFLUENZA;

ADOLESCENT; ADULT; AGED; CHINA; CYTOKINES; FEMALE; HUMANS; INFLUENZA A VIRUS, H7N9 SUBTYPE; INFLUENZA, HUMAN; MALE; MIDDLE AGED;

CHEMOKINE; CYTOKINE; H7N9 AVIAN INFLUENZA;

EID: 84897117203     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jit440     Document Type: Article

References (12)

1. Gao R, Cao B, Hu Y, et al. Human infection with a novel avian-origin influenza A (H7N9) virus. N Engl J Med 2013; 368:1888-97.
2. de Jong MD, Simmons CP, Thanh TT, et al. Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia. Nat Med 2006; 12:1203-7.
3. Seo SH, Hoffmann E, Webster RG. Lethal H5N1 influenza viruses escape host anti-viral cytokine responses. Nat Med 2002; 8:950-4.
4. Cheung CY, Poon IX, Lau AS, et al. Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: A mechanism for the unusual severity of human disease? Lancet 2002; 360:1831-7.
5. Lipatov AS, Andreansky S, Webby RJ, et al. Pathogenesis of Hong Kong H5N1 influenza virus NS gene reassortants in mice: The role of cytokines and B- and T-cell responses. J Gen Virol 2005; 86:1121-30.
6. Chan MC, Cheung CY, Chui WH, et al. Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells. Respir Res 2005; 6:135.
7. Chen Y, Liang W, Yang S, et al. Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterisation of viral genome. Lancet 2013; 381:1916-25.
8. Bermejo-Martin JF, Ortiz de Lejarazu R, Pumarola T, et al. Thl and Thl7 hypercytokinemia as early host response signature in severe pandemic influenza. Crit Care 2009; 13:R201.
9. Yu X, Zhang X, Zhao B, et al. Intensive cytokine induction in pandemic H1N1 influenza virus infection accompanied by robust production of IL-10 and IL-6. PLoS One 2011; 6:e28680.
10. Hagau N, Slavcovici A, Gonganau DN, et al. Clinical aspects and cytokine response in severe H1N1 influenza A virus infection. Crit Care 2010; 14:R203.
11. Peiris JS, Yu WC, Leung CW, et al. Re-emergence of fatal human influenza A subtype H5N1 disease. Lancet 2004; 363:617-9.
12. Wong CK, Lam CW, Wu AK, et al. Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome. Clin Exp Immunol 2004; 136:95-103.