Retinoic acid receptor alpha: One of plasma biomarkers associated with exacerbation of chronic obstructive pulmonary disease

COPD: Journal of Chronic Obstructive Pulmonary Disease

Volumn 11, Issue 2, 2014, Pages 152-162

  Heo, Jeong Seok ^a   Park, Jong Sook ^a   Lee, Eun Ju ^a   Kim, Tae Hoon ^a   Jang, An Soo ^a   Park, Sung Woo ^a   Kim, Ji Na ^a   Kim, Yang Gi ^a   Uh, Soo Taek ^a   Choi, Jae Seong ^a   Na, Joo Ok ^a   Kim, Yong Hoon ^a   Jeong, Sung Hwan ^b   Kim, Yong Bae ^a   Kim, Sung Ryul ^a   Park, Choon Sik ^a  

^a Soonchunhyang University   (South Korea)

^b Gachon University   (South Korea)

Author keywords

2DE; COPD; ELISA; Exacerbation; RAR alpha; ROC curve

Indexed keywords

ALPHA 1 ANTITRYPSIN; ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; BIOLOGICAL MARKER; CELL PROTEIN; COMPLEMENT FACTOR; COMPLEMENT FACTOR B PREPROPROTEIN; FIBRIN; FIBRIN BETA; FIBRINOGEN; FIBRINOGEN GAMMA; PEPTIDASE; PHOSPHODIESTERASE; PROTEIN NINEIN; REGULATOR PROTEIN; RETINOIC ACID RECEPTOR ALPHA; SERPINE PEPTIDASE INHIBITOR MEMBER 6; T LYMPHOCYTE RECEPTOR DELTA CHAIN; TRANSFERRIN; TYROSYL DNA PHOSPHODIESTERASE 2; UNCLASSIFIED DRUG; WD REPEAT CONTAINING PROTEIN 1 ISOFORM 1; RETINOIC ACID RECEPTOR;

ADULT; AGED; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISEASE EXACERBATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HOSPITAL ADMISSION; HOSPITALIZATION; HUMAN; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MIDDLE AGED; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEOMICS; SENSITIVITY AND SPECIFICITY; TWO DIMENSIONAL ELECTROPHORESIS; BLOOD; BODY MASS; CASE CONTROL STUDY; COMPLICATION; LUNG FUNCTION TEST; MASS SPECTROMETRY; PREDICTIVE VALUE; RECEIVER OPERATING CHARACTERISTIC; RISK FACTOR; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; BODY MASS INDEX; CASE-CONTROL STUDIES; FEMALE; HOSPITALIZATION; HUMANS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RECEPTORS, RETINOIC ACID; RESPIRATORY FUNCTION TESTS; RISK FACTORS; ROC CURVE; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 84897091295     PISSN: 15412555     EISSN: 15412563     Source Type: Journal    
DOI: 10.3109/15412555.2013.828028     Document Type: Article

References (52)

1. CD Mathers, DM Fat, JT Boerma. The Global Burden of Disease: 2004 Update. Geneva: World Health Organization; 2008.
2. DW Brown, JB Croft, PhD, KJ Greenlund, PhD, WH Giles, MD. Deaths from Chronic Obstructive Pulmonary Disease-United States, (2000-2005). Centers for Disease Control and Prevention. Atlanta, USA 2008 / 57(45); 1229-1232.
3. Mathers CD, Loncar D. Projection of global mortality and burden of diseases from 2002 to 2030. PloS Med 2006; 3:e442.
4. Burrows B, Earle RH. Course and prognosis of chronic obstructive lung disease: A prospective study of 200 patients. N Engl J Med 1969; 280:397-404.
5. B Celli, GL Snider, J Heff ner. Defi nitions, epidemiology, pathophysiology, diagnosis, and staging. Am J Respir Crit Care Med 1995; 152: Suppl: S78-S83.
6. Hurst JR, Vestbo J, Anzueto A, et al: Susceptibility to exacerbation in chronic obstructive pulmonary disease. N Engl J Med 2010; 363:1128-38.
7. Decramer M, Celli B, Kesten S, Lystig T, Mehra S, Tashkin DP. Effect of tiotropium on outcomes in patients with moderate chronic obstructive pulmonary disease (UPLIFT): A prespecifi ed subgroup analysis of a randomized controlled trial. Lancet 2009; 374:1171-1178.
8. Gudmundsson G, Gislason T, Lindberg E, Hallin R, UlrikCS, Brøndum E, NieminenMM, Aine T, Bakke P, Janson C. Mortality in COPD patients discharged from hospital: The role of treatment and co-morbidity. Respir Res 2006; 7:109
9. Celli BR, Cote CG, Marin JM, et al. The body-mass index, airfl ow obstruction, dyspnea, and exercise capacity index in Chronic Obstructive Pulmonary Disease. N Engl J Med 2004; 350:1005-1012.
10. .10. Gan WQ, Man SF, Senthilselvan A, Sin DD. Association between chronic obstructive pulmonary disease and systemic infl ammation: A systematic review and a meta-Analysis. Thorax 2004; 59:574-580.
11. Pinto-Plata V, Toso J, Lee K, Parks D, Bilello J, Mullerova H,De Souza MM, Vessey R, Celli B. Profi ling serum biomarkers in patients with COPD: Associations with clinical parameters. Thorax 2007; 62:595-601.
12. Dahl M, Tybjaerg-Hansen A, Vestbo J, et al. Elevated plasma fi brinogen associated with reduced pulmonary function and increased risk of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2001; 164:1008-1125.
13. Koutsokera A, Stolz D, Loukides S, Kostikas K. Systemic biomarkers in exacerbations of COPD: The evolving clinical challenge. CHEST 2012; 141(2):396-405.
14. Global Initiative for Chronic Obstructive Lung Disease-GOLD [home page on The Internet]. Bethesda: Global Initiative for Chronic Obstructive Lung Disease [cited 2012 Mar 13]. Global strategy for The diagnosis, management and prevention of COPD-Revised 2011. [Adobe Acrobat document, 90p.]. Available from: Http://www.goldcopd.org/uploads/users/fi les/ GOLD-Report-2011-Feb21.pdf
15. Rhim T, Choi YS, Nam BY, Uh ST, Park JS, Kim YH, Paik YK, Park CS. Plasma protein profi les in early asthmatic responses to inhalation allergen challenge. Allergy 2009; 64(1):47-54.
16. Shevchenko A, Wilm M, Vorm O, Mann M, Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem 1996; 68:850-858.
17. Maden M, Hind M. Retinoic acid in alveolar development, maintenance and regeneration. Philos Trans Roy Soc Lond B: Biol Sci 2004; 359:799.
18. McGowan S, Jackson SK, Jenkins-Moore M, Dai HH, Chambon P, Snyder JM. Mice bearing deletions of retinoic acid receptors demonstrate reduced lung elastin and alveolar numbers. Am J Respir Cell Mol Biol 2000; 23:162-167.
19. Vogel S, Gamble MV, Blaner WS. Biosynthesis, absorption, metabolism and transport of retinoids. In: Retinoids. The Biochemical and Molecular Basis of Vitamin A and Retinoid Action. Nau H, Blaner WS, eds.; Berlin: Springer-Verlag, 1999.
20. Frankenberger M, Hauck RW, Frankenberger B, Haussinger K, Maier KL, Heyder J, Ziegler-Heitbrock HW. All trans-retinoic acid selectively down-regulates matrix metalloproteinase-9 (MMP-9) and up-regulates tissue inhibitor of metalloproteinase-1 (TIMP-1) in human bronchoalveolar lavage cells. Mol Med 2001; 7:263.
21. Mao JT, Tashkin DP, Belloni PN, Baileyhealy I, Baratelli F, Roth MD. All-Trans retinoic acid modulates The balance of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in patients with emphysema. Chest 2003; 124:1724-1732.
22. Ross AC. Retinoid production and catabolism: Role of diet in regulating retinol esterifi cation and retinoic acid oxidation. J Nutr 2003; 133: 291S-196S.
23. Wang XD, Liu C, Bronson RT, Smith DE, Krinsky NI, Russell M. Retinoid signaling and activator protein-1 expression in ferrets given beta-carotene supplements and exposed to tobacco smoke. J Natl Cancer Inst 1999; 91:60-66.
24. Gordon C, Gudi K, Krause A, Sackrowitz R, Harvey B-G, Strulovici-Barel Y, Mezey JG, Crystal RG. Circulating endothelial microparticles as a measure of early lung destruction in cigarette smokers. Am J Respir Crit Care Med 2011; 184:224-232.
25. Demedts IK, Demoor T, Bracke KR, Joos GF, Brusselle GG. Role of apoptosis in The pathogenesis of COPD and pulmonary emphysema. Respir Res 2006; 7:53
26. Barreiro E, Ferrer D, Sanchez F, Minguella J, Marin-Corral J, Martinez-Llorens J, Lloreta J, Gea J. Infl ammatory cells and apoptosis in respiratory and limb muscles of patients with COPD. J Appl Physiol 2011 Sep; 111(3):808-817.
27. Lim SC, Ju JY, Chi SY, Ban HJ, Kwon YS, Oh IJ, Kim KS, Kim YI, Kim YC. Apoptosis of T lymphocytes isolated from peripheral blood of patients with acute exacerbation of chronic obstructive pulmonary disease. Yonsei Med J 2011; 52(4):581-587.
28. Hacker S, Lambers C, Pollreisz A, et al. Increased soluble serum markers caspase-cleaved cytokeratin-18, histones, and ST2 indicate apoptotic turnover and chronic immune response in COPD J Clin Lab Anal 2009; 23: 372-379.
29. Tilley AE, O'Connor TP, Hackett NR, Strulovici-Barel Y, Salit J, et al. Biologic phenotyping of The human small airway epithelial response to cigarette smoking. PLoS ONE 2011; 6(7):e22798.
30. Beane J, Shah V, Liu G, Schembri F, Yang X, Palma J, Brody JS. Effects of cigarette smoke on The human airway epithelial cell transcriptome. Proc Natl Acad Sci USA 2004; 101:10143-10148.
31. Pierrou S, Broberg P, O'Donnell RA, Pawlowski K, Virtala R, et al. Expression of genes involved in oxidative stress responses in airway epithelial cells of smokers with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2007; 175:577-586.
32. Blacque OE, Li C, Inglis PN, Esmail MA, Ou G, Mah AK, Baillie DL, Scholey JM, Leroux MR. The WD Repeat-containing Protein IFTA-1 Is required for retrograde intrafl agellar transport. Mol Biol Cell 2006; 17(12):5053-5062.
33. Yaghi A, Zaman A, Cox G, Dolovich MB. Ciliary beating is depressed in nasal cilia from chronic obstructive pulmonary disease subjects. Respir Med 2012; 106(8):1139-1147.
34. Murai J, Huang SY, Das BB, Dexheimer TS, Takeda S, Pommier Y. Tyrosyl-DNA phosphodiesterase 1 (TDP1) repairs DNA damage induced by topoisomerases I and II and base alkylation in vertebrate cells. J Biol Chem 2012; 287(16):12848-12857. Epub 2012 Feb 27.
35. Jameson J, Witherden D, Havran WL. T-cell Effector mechanisms: Gammadelta and CD1d-restricted subsets. Curr Opin Immunol 2003; 15:349-353.
36. Pons J, Sauleda J, Ferrer JM, Barceló B, Fuster A, Regueiro V, Julià MR, Agustí AG. Blunted gamma delta T-lymphocyte response in chronic obstructive pulmonary disease. Eur Respir J 2005; 25(3):441-446.
37. Cox DW. Alpha-1 antitrypsin defi ciency. In: Scriver CR, Beaudet AL, Sly WS, et al., eds. The Metabolic and Molecular Bases of Inherited Disease. 8th Ed.; Vol. 4. New York: McGraw-Hill, 2001: 5559-5584.
38. Scott FL, Hirst CE, Sun J, Bird CH, Bottomley SP, Bird PI. The intracellular serpin proteinase Inhibitor 6 Is expressed in monocytes and granulocytes and is a potent inhibitor of The azurophilic granule protease, Cathepsin G. Blood 1999; 93:2089-2097.
39. Zhou Q, Salvesen GS. Activation of pro-caspase-7 by serine proteases includes a non-canonical specifi city. Biochem J 1997; 324:361.
40. Scott FL, Coughlin PB, Bird C, Cerruti L, Hayman JA, Bird P. Proteinase inhibitor 6 cannot be secreted, which suggests it is a new type of cellular serpin. J Biol Chem 1996; 271:1605.
41. Farrell DH. Pathophysiologic roles of The fi brinogen gamma chain. Curr Opin Hematol 2004; 11:151-155.
42. Mosesson MW. Fibrinogen gamma chain functions. J Thromb Haemost 2003; 1:231-238.
43. Schols A, Mostert R, Soeters P, Greve LH, Wouters EF. Inventory of nutritional status in patients with COPD. Chest 1989 Aug; 96(2):247-249.
44. MacNee W. Pathogenesis of Chronic Obstructive Pulmonary Disease. Proc Am Thorac Soc 2005; 2:258-266.
45. Perera WR, Donaldson GC, Wedzicha JA, et al. Infl ammatory changes, recovery and recurrence at COPD exacerbation. Eur Respir J 2007; 29:527-534.
46. Hurst JR, Donaldson GC, Wedzicha A, et al. Use of plasma biomarkers at exacerbation of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2006; 174:867-874.
47. Seligman R, Papassotiriou J, Morgenthaler NG, Meisner M, Teixeira PJZ. Copeptin, a novel prognostic biomarker in ventilator-Associated pneumonia. CHEST 2007; 131:1058-1067.
48. Rodriguez-Roisin R. Toward a consensus defi nition for COPD exacerbations. Chest 2000; 117:398S-401S.
49. Terracciano R, Preiano M, et al. Peptidome profi ling of induced sputum by mesoporous silica beads and MALDI-TOF MS for non-invasive biomarker discovery of chronic infl ammatory lung diseases. Proteomics 2011, 11, 3402-3414.
50. Lee EJ, In KH, et al. Proteomic analysis in lung tissue of smokers and COPD patients. CHEST 2009; 135:344-352.
51. Verrills NM, Irwin JA, He XY, et al. Identifi cation of novel diagnostic biomarkers for asthma and Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med 2011; 183:1633-1643.
52. Pastor MD, Nogal A, et al. Identifi cation of oxidative stress related proteins as biomarkers for lung cancer and Chronic Obstructive Pulmonary Disease in bronchoalveolar lavage. Int J Mol Sci 2013; 14:3440-3455.