Domino 1,3-dipolar cycloadditions of n- alkyl-α-amino esters with paraformaldehyde: A direct access to α-hydroxymethyl α-amino acids

Synthesis (Germany)

Volumn 46, Issue 7, 2014, Pages 967-971

  Castelló, Luis M ^a   Nájera, Carmen ^a   Sansano, José M ^a  

^a UNIVERSITY OF ALICANTE   (Spain)

Author keywords

azomethine ylides; cycloaddition; paraformaldehyde; serine

Indexed keywords

AMINO ACIDS; CYCLOADDITION; ESTERIFICATION; ESTERS; METHANOL; REACTION KINETICS;

1 ,3-DIPOLAR CYCLOADDITIONS; 1 ,3-DIPOLARCYCLOADDITION; AZOMETHINE YLIDES; DIASTEREOSELECTIVE; DOMINO REACTIONS; ENANTIOMERIC RATIO; PARAFORMALDEHYDES; SERINE;

ACETAL RESINS;

ALPHA (HYDROXYMETHYL)PROLINE; ALPHA HYDROXYMETHYL ALPHA AMINO ACID; AZOMETHINE YLIDE; DIETHYL 3 BENZYLOXAZOLIDINE 4,4 DICARBOXYLIC ACID; ETHYL 3 BENZYLOXAZOLIDINE 4 CARBOXYLIC ACID; FORMALDEHYDE; METHYL 2 (HYDROXYMETHYL)INDOLINE 2 CARBOXYLIC ACID; METHYL 3 METHYLOXAZOLIDINE 4 CARBOXYLIC ACID; METHYL HEXAHYDRO 1H OXAZOLO[3,4 A]PYRIDINE 8A CARBOXYLIC ACID; METHYL HEXAHYDROPYRROLO[1,2 C]OXAZOLE 7A CARBOXYLIC ACID; N ALKYL ALPHA AMINO ESTER; N METHYL DEXTRO SERINE; OXAZOLIDINE DERIVATIVE; PARAFORMALDEHYDE; SARCOSINE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; CHEMICAL REACTION; COMPLEX FORMATION; CYCLOADDITION; DIASTEREOSELECTIVE; DOMINO REACTION; HYDROLYSIS; STEREOCHEMISTRY;

EID: 84897071861     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0033-1340816     Document Type: Article

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