Differential contribution of afferent and central pathways to the development of baroreflex dysfunction in chronic kidney disease

Hypertension

Volumn 63, Issue 4, 2014, Pages 804-810

  Salman, Ibrahim M ^a   Hildreth, Cara M ^a   Ameer, Omar Z ^a   Phillips, Jacqueline K ^a  

^a MACQUARIE UNIVERSITY   (Australia)

Author keywords

baroreflex; heart rate; hypertension; renal insufficiency chronic; sympathetic nervous system

Indexed keywords

CALCIUM; COLLAGEN; CREATININE; ELASTIN; NITROPRUSSIDE SODIUM; PHENYLEPHRINE;

ADRENERGIC TRANSMISSION; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ARCH; AORTIC DEPRESSOR NERVE ACTIVITY; ARTICLE; BAROREFLEX DYSFUNCTION; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; CREATININE URINE LEVEL; ELECTROSTIMULATION; HEART RATE; JUVENILE ANIMAL; KIDNEY POLYCYSTIC DISEASE; LPK RAT; MALE; MEAN ARTERIAL PRESSURE; MORPHOMETRICS; NERVE CONDUCTION; NONHUMAN; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; PROTEIN URINE LEVEL; PULSE PRESSURE; RAT; REFLEX DISORDER; RENAL SYMPATHETIC NERVE ACTIVITY; SYSTOLIC BLOOD PRESSURE;

BAROREFLEX; HEART RATE; HYPERTENSION; RENAL INSUFFICIENCY, CHRONIC; SYMPATHETIC NERVOUS SYSTEM;

AFFERENT PATHWAYS; AGING; ANIMALS; BAROREFLEX; BLOOD PRESSURE; CENTRAL NERVOUS SYSTEM; DISEASE MODELS, ANIMAL; HEART RATE; KIDNEY; MALE; RATS; RATS, INBRED LEW; RENAL INSUFFICIENCY, CHRONIC; SYMPATHETIC NERVOUS SYSTEM;

EID: 84897062235     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.113.02110     Document Type: Article

References (29)

1. Cashion AK, Cowan PA, Milstead EJ, Gaber AO, Hathaway DK. Heart rate variability, mortality, and exercise in patients with end-stage renal disease. Prog Transplant. 2000;10:10-16.
2. Dursun B, Demircioglu F, Varan HI, Basarici I, Kabukcu M, Ersoy F, Ersel F, Suleymanlar G. Effects of different dialysis modalities on cardiac auto-nomic dysfunctions in end-stage renal disease patients: one year prospective study. Ren Fail. 2004;26:35-38.
3. Converse RL Jr, Jacobsen TN, Toto RD, Jost CM, Cosentino F, Fouad-Tarazi F, Victor RG. Sympathetic overactivity in patients with chronic renal failure. N Engl J Med. 1992;327:1912-1918.
4. Hausberg M, Kosch M, Harmelink P, Barenbrock M, Hohage H, Kisters K, Dietl KH, Rahn KH. Sympathetic nerve activity in end-stage renal disease. Circulation. 2002;106:1974-1979.
5. Klein IH, Ligtenberg G, Oey PL, Koomans HA, Blankestijn PJ. Sympathetic activity is increased in polycystic kidney disease and is associated with hypertension. J Am Soc Nephrol. 2001;12:2427-2433.
6. Zoccali C, Mallamaci F, Tripepi G, Parlongo S, Cutrupi S, Benedetto FA, Cataliotti A, Malatino LS; CREED investigators. Norepinephrine and concentric hypertrophy in patients with end-stage renal disease. Hypertension. 2002;40:41-46.
7. Harrison JL, Hildreth CM, Callahan SM, Goodchild AK, Phillips JK. Cardiovascular autonomic dysfunction in a novel rodent model of poly-cystic kidney disease. Auton Neurosci. 2010;152:60-66.
8. La Rovere MT, Bigger JT Jr, Marcus FI, Mortara A, Schwartz PJ. Barorefex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial infarction. ATRAMI (Autonomic Tone and Refexes After Myocardial Infarction) Investigators. Lancet. 1998;351:478-484.
9. Tinucci T, Abrahão SB, Santello JL, Mion D Jr. Mild chronic renal insuffciency induces sympathetic overactivity. J Hum Hypertens. 2001;15:401-406.
10. Lacy P, Carr SJ, O'Brien D, Fentum B, Williams B, Paul SK, Robinson TG. Reduced glomerular fltration rate in pre-dialysis non-diabetic chronic kidney disease patients is associated with impaired baroreceptor sensitivity and reduced vascular compliance. Clin Sci (Lond). 2006;110:101-108.
11. Johansson M, Gao SA, Friberg P, Annerstedt M, Carlström J, Ivarsson T, Jensen G, Ljungman S, Mathillas O, Nielsen FD, Strömbom U. Barorefex effectiveness index and barorefex sensitivity predict all-cause mortality and sudden death in hypertensive patients with chronic renal failure. J Hypertens. 2007;25:163-168.
12. Ligtenberg G, Blankestijn PJ, Oey PL, Klein IH, Dijkhorst-Oei LT, Boomsma F, Wieneke GH, van Huffelen AC, Koomans HA. Reduction of sympathetic hyperactivity by enalapril in patients with chronic renal failure. N Engl J Med. 1999;340:1321-1328.
13. Ninomiya I, Nisimaru N, Irisawa H. Sympathetic nerve activity to the spleen, kidney, and heart in response to baroceptor input. Am J Physiol. 1971;221:1346-1351.
14. McCooke JK, Appels R, Barrero RA, Ding A, Ozimek-Kulik JE, Bellgard MI, Morahan G, Phillips JK. A novel mutation causing nephronophthisis in the Lewis polycystic kidney rat localises to a conserved RCC1 domain in Nek8. BMC Genomics. 2012;13:393.
15. Hildreth CM, Kandukuri DS, Goodchild AK, Phillips JK. Temporal development of baroreceptor dysfunction in a rodent model of chronic kidney disease. Clin Exp Pharmacol Physiol. 2013;40:458-465.
16. Phillips JK, Hopwood D, Loxley RA, Ghatora K, Coombes JD, Tan YS, Harrison JL, McKitrick DJ, Holobotvskyy V, Arnolda LF, Rangan GK. Temporal relationship between renal cyst development, hypertension and cardiac hypertrophy in a new rat model of autosomal recessive polycystic kidney disease. Kidney Blood Press Res. 2007;30:129-144.
17. Ng K, Hildreth CM, Phillips JK, Avolio AP. Aortic stiffness is associated with vascular calcifcation and remodeling in a chronic kidney disease rat model. Am J Physiol Renal Physiol. 2011;300:F1431-F1436.
18. Sapru HN, Wang SC. Modifcation of aortic barorecptor resetting in the spontaneously hypertensive rat. Am J Physiol. 1976;230:664-674.
19. Gordon FJ, Mark AL. Mechanism of impaired barorefex control in prehy-pertensive Dahl salt-sensitive rats. Circ Res. 1984;54:378-387.
20. Grassi G, Trevano FQ, Seravalle G, Scopelliti F, Mancia G. Barorefex function in hypertension: consequences for antihypertensive therapy. Prog Cardiovasc Dis. 2006;48:407-415.
21. Chesterton LJ, Sigrist MK, Bennett T, Taal MW, McIntyre CW. Reduced barorefex sensitivity is associated with increased vascular calcifcation and arterial stiffness. Nephrol Dial Transplant. 2005;20:1140-1147.
22. Kocyigit I, Kaya MG, Orscelik O, Kaya C, Akpek M, Zengin H, Sipahioglu MH, Unal A, Yilmaz MI, Tokgoz B, Oymak O, Axelsson J. Early arterial stiffness and infammatory bio-markers in normotensive polycystic kidney disease patients. Am J Nephrol. 2012;36:11-18.
23. Fan W, Andresen MC. Differential frequency-dependent refex integration of myelinated and nonmyelinated rat aortic baroreceptors. Am J Physiol. 1998;275(2 Pt 2):H632-H640.
24. Gonzalez ER, Krieger AJ, Sapru HN. Central resetting of barorefex in the spontaneously hypertensive rat. Hypertension. 1983;5:346-352.
25. Zhang J, Miffin SW. Integration of aortic nerve inputs in hypertensive rats. Hypertension. 2000;35(1 Pt 2):430-436.
26. Huber DA, Schreihofer AM. Attenuated barorefex control of sympathetic nerve activity in obese Zucker rats by central mechanisms. J Physiol. 2010;588(Pt 9):1515-1525.
27. Huber DA, Schreihofer AM. Altered regulation of the rostral ventrolat-eral medulla in hypertensive obese Zucker rats. Am J Physiol Heart Circ Physiol. 2011;301:H230-H240.
28. Smith JK, Barron KW. GABAergic responses in ventrolateral medulla in spontaneously hypertensive rats. Am J Physiol. 1990;258(2 Pt 2):R450-R456.
29. Grassi G, Quarti-Trevano F, Seravalle G, Arenare F, Volpe M, Furiani S, Dell'Oro R, Mancia G. Early sympathetic activation in the initial clinical stages of chronic renal failure. Hypertension. 2011;57:846-851.