Cardiovascular autonomic dysfunction in a novel rodent model of polycystic kidney disease

Autonomic Neuroscience: Basic and Clinical

Volumn 152, Issue 1-2, 2010, Pages 60-66

  Harrison, Joanne L ^a   Hildreth, Cara M ^b   Callahan, Stephen M ^a   Goodchild, Ann K ^b   Phillips, Jacqueline K ^a,b  

^a MURDOCH UNIVERSITY   (Australia)

^b MACQUARIE UNIVERSITY   (Australia)

Author keywords

Baroreflex function; Heart rate variability; Hypertension; Parasympathetic; Sympathetic

Indexed keywords

ATENOLOL; METHYLATROPINE; NITROPRUSSIDE SODIUM; PHENYLEPHRINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTONOMIC DYSFUNCTION; BLOOD PRESSURE VARIABILITY; CARDIOVASCULAR DISEASE; COMPARATIVE STUDY; CONTROL GROUP; CONTROLLED STUDY; EXPERIMENTAL MODEL; HEART BEAT; HEART RATE; HYPERTENSION; KIDNEY POLYCYSTIC DISEASE; MALE; NONHUMAN; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; SYSTOLIC BLOOD PRESSURE;

ANIMALS; ANTIHYPERTENSIVE AGENTS; ATENOLOL; ATROPINE DERIVATIVES; AUTONOMIC NERVOUS SYSTEM; BAROREFLEX; BLOOD PRESSURE; CARDIOVASCULAR SYSTEM; DISEASE MODELS, ANIMAL; ELECTROPHYSIOLOGIC TECHNIQUES, CARDIAC; FOURIER ANALYSIS; HEART RATE; HYPERTENSION; MALE; NITROPRUSSIDE; PARASYMPATHOLYTICS; POLYCYSTIC KIDNEY, AUTOSOMAL RECESSIVE; RATS; RATS, INBRED LEW; SIGNAL PROCESSING, COMPUTER-ASSISTED;

EID: 72049102118     PISSN: 15660702     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autneu.2009.09.019     Document Type: Article

References (63)

1. Andresen M.C., Kuraoka S., and Brown A.M. Baroreceptor function and changes in strain sensitivity in normotensive and spontaneously hypertensive rats. Circ. Res. 47 (1980) 821-828
2. Augustyniak R.A., Tuncel M., Zhang W., Toto R.D., and Victor R.G. Sympathetic overactivity as a cause of hypertension in chronic renal failure. J. Hypertens. 20 (2002) 3-9
3. Bardaji A., Martinez-Vea A., Valero A., Gutierrez C., Garcia C., Ridao C., Oliver J.A., and Richart C. Cardiac involvement in autosomal-dominant polycystic kidney disease: a hypertensive heart disease. Clin. Nephrol. 56 (2001) 211-220
4. Braga V.A., Burmeister M.A., Sharma R.V., and Davisson R.L. Cardiovascular responses to peripheral chemoreflex activation and comparison of different methods to evaluate baroreflex gain in conscious mice using telemetry. Am. J. Physiol. Regul. Integr. Comp. Physiol. 295 (2008) R1168-R1174
5. Brown D.R., Brown L.V., Patwardhan A., and Randall D.C. Sympathetic activity and blood pressure are tightly coupled at 0.4 Hz in conscious rats. Am. J. Physiol. 267 (1994) R1378-R1384
6. Burke S.L., and Head G.A. Method for in vivo calibration of renal sympathetic nerve activity in rabbits. J. Neurosci. Methods 127 (2003) 63-74
7. Capisonda R., Phan V., Traubuci J., Daneman A., Balfe J.W., and Guay-Woodford L.M. Autosomal recessive polycystic kidney disease: outcomes from a single-center experience. Pediatr. Nephrol. 18 (2003) 119-126
8. Cashion A.K., Cowan P.A., Milstead E.J., Gaber A.O., and Hathaway D.K. Heart rate variability, mortality, and exercise in patients with end-stage renal disease. Prog. Transplant. 10 (2000) 10-16
9. Cerasola G., Vecchi M., Mule G., Cottone S., Mangano M.T., Andronico G., Contorno A., Parrino I., Renda F., and Pavone G. Sympathetic activity and blood pressure pattern in autosomal dominant polycystic kidney disease hypertensives. Am. J. Nephrol. 18 (1998) 391-398
10. Cerutti C., Barres C., and Paultre C. Baroreflex modulation of blood pressure and heart rate variabilities in rats: assessment by spectral analysis. Am. J. Physiol. 266 (1994) H1993-H2000
11. Dursun B., Demircioglu F., Varan H.I., Basarici I., Kabukcu M., Ersoy F., Ersel F., and Suleymanlar G. Effects of different dialysis modalities on cardiac autonomic dysfunctions in end-stage renal disease patients: one year prospective study. Ren. Fail. 26 (2004) 35-38
12. Fall P.J., and Prisant L.M. Polycystic kidney disease. J. Clin. Hypertens. 7 (2005) 617-625
13. Friberg P., Karlsson B., and Nordlander M. Autonomic control of the diurnal variation in arterial blood pressure and heart rate in spontaneously hypertensive and Wistar-Kyoto rats. J. Hypertens. 7 (1989) 799-807
14. Fukuta H., Hayano J., Ishihara S., Sakata S., Mukai S., Ohte N., Ojika K., Yagi K., Matsumoto H., Sohmiya S., and Kimura G. Prognostic value of heart rate variability in patients with end-stage renal disease on chronic haemodialysis. Nephrol. Dial. Transplant. 18 (2003) 318-325
15. Gabow P.A., Chapman A.B., and Johnson A.M. Renal structure and hypertension in autosomal dominant polycystic kidney disease. Kidney Int. 38 (1990) 1177-1180
16. Gattone II V.H., Siqueira Jr. T.M., Powell C.R., Trambauugh C.M., Lingeman J.E., and Shalhav A.L. Contribution of renal innervation to hypertension in rat autosomal dominant polycystic kidney disease. Exp. Biol. Med. 233 (2008) 952-957
17. Guay-Woodford L.M. Murine models of polycystic kidney disease: molecular and therapeutic insights. Am. J. Physiol. Renal Physiol. 285 (2003) F1034-F1049
18. Guyenet P.G., Filtz T.M., and Donaldson S.R. Role of excitatory amino acids in rat vagal and sympathetic baroreflexes. Brain Res. 407 (1987) 272-284
19. Harris D.C., and Rangan G.K. Retardation of kidney failure - applying principles to practice. Ann. Acad. Med. Singap. 34 (2005) 16-23
20. Henze M., Hart D., Samarel A., Barakat J., Eckert L., and Scrogin K. Persistent alterations in heart rate variability, baroreflex sensitivity, and anxiety-like behaviors during development of heart failure in the rat. Am. J. Physiol. Heart Circ. Physiol. 295 (2008) H29-H38
21. Hesse C., Charkoudian N., Liu Z., Joyner M.J., and Eisenach J.H. Baroreflex sensitivity inversely correlates with ambulatory blood pressure in healthy normotensive humans. Hypertension 50 (2007) 41-46
22. Hildreth C.M., Padley J.R., Pilowsky P.M., and Goodchild A.K. Impaired serotonergic regulation of heart rate may underlie reduced baroreflex sensitivity in an animal model of depression. Am. J. Physiol. Heart Circ. Physiol. 294 (2008) H474-H480
23. Johansson M., Gao S.A., Friberg P., Annerstedt M., Bergstrom G., Carlstrom J., Ivarsson T., Jensen G., Ljungman S., Mathillas O., Nielsen F.-D., and Strombom U. Reduced baroreflex effectiveness index in hypertensive patients with chronic renal failure. Am. J. Hypertens. 18 (2005) 995-1000
24. Kingwell B.A., Thompson J.M., Kaye D.M., McPherson G.A., Jennings G.L., and Esler M.D. Heart rate spectral analysis, cardiac norepinephrine spillover, and muscle sympathetic nerve activity during human sympathetic nervous activation and failure. Circulation 90 (1994) 234-240
25. Klein I.H., Ligtenberg G., Oey P.L., Koomans H.A., and Blankestijn P.J. Sympathetic activity is increased in polycystic kidney disease and is associated with hypertension. J. Am. Soc. Nephrol. 12 (2001) 2427-2433
26. La Rovere M.T., Bigger Jr. J.T., Marcus F.I., Mortara A., and Schwartz P.J. Baroreflex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial infarction. ATRAMI (Autonomic Tone and Reflexes After Myocardial Infarction) Investigators. Lancet 351 (1998) 478-484
27. La Rovere M.T., Pinna G.D., Hohnloser S.H., Marcus F.I., Mortara A., Nohara R., Bigger Jr. J.T., Camm A.J., and Schwartz P.J. Baroreflex sensitivity and heart rate variability in the identification of patients at risk for life-threatening arrhythmias: implications for clinical trials. Circulation 103 (2001) 2072-2077
28. La Rovere M.T., Pinna G.D., and Raczak G. Baroreflex sensitivity: measurement and clinical implications. Ann. Noninvasive Electrocardiol. 13 (2008) 191-207
29. La Rovere M.T., Pinna G.D., Maestri R., Robbi E., Caporotondi A., Guazzotti G., Sleight P., and Febo O. Prognostic implications of baroreflex sensitivity in heart failure patients in the beta-blocking era. J. Am. Coll. Cardiol. 53 (2009) 193-199
30. Locatelli F., Pozzoni P., Tentori F., and del Vecchio L. Epidemiology of cardiovascular risk in patients with chronic kidney disease. Nephrol. Dial. Transplant. 18 Suppl 7 (2003) 2-9
31. Mancia G., Ferrari A., Gregorini L., Parati G., Pomidossi G., Bertinieri G., Grassi G., di Rienzo M., Pedotti A., and Zanchetti A. Blood pressure and heart rate variabilities in normotensive and hypertensive human beings. Circ. Res. 53 (1983) 96-104
32. Mancia G., Frattola G., Parati C., Santuccin C., and Ulian L. Blood pressure variabilty and organ damage. J. Cardiovasc. Pharmacol. 24 (1994) S6-S11
33. Mancia G., Giannattasio C., Failla M., Sega R., and Parati G. Systolic blood pressure and pulse pressure: role of 24-h mean values and variability in the determination of organ damage. J. Hypertens. Suppl. 17 (1999) S55-S61
34. Miao C.Y., Xie H.H., Zhan L.S., and Su D.F. Blood pressure variability is more important than blood pressure level in determination of end-organ damage in rats. J. Hypertens. 24 (2006) 1125-1135
35. Monahan K.D. Effect of aging on baroreflex function in humans. Am. J. Physiol. Regul. Integr. Comp. Physiol. 293 (2007) R3-R12
36. Murphy C.A., Sloan R.P., and Myers M.M. Pharmacologic responses and spectral analyses of spontaneous fluctuations in heart rate and blood pressure in SHR rats. J. Auton. Nerv. Syst. 36 (1991) 237-250
37. Neumann J., Ligtenberg G., Klein I.H., and Blankestijn P.J. Pathogenesis and treatment of hypertension in polycystic kidney disease. Curr. Opin. Nephrol. Hypertens. 11 (2002) 517-521
38. Notarius C.F., and Floras J.S. Limitations of the use of spectral analysis of heart rate variability for the estimation of cardiac sympathetic activity in heart failure. Europace 3 (2001) 29-38
39. Padley J.R., Overstreet D.H., Pilowsky P.M., and Goodchild A.K. Impaired cardiac and sympathetic autonomic control in rats differing in acetylcholine receptor sensitivity. Am. J. Physiol. Heart Circ. Physiol. 289 (2005) H1985-H1992
40. Pagani M., Montano N., Porta A., Malliani A., Abboud F.M., Birkett C., and Somers V.K. Relationship between spectral components of cardiovascular variabilities and direct measures of muscle sympathetic nerve activity in humans. Circulation 95 (1997) 1441-1448
41. Parati G., Pomidossi G., Albini F., Malaspina D., and Mancia G. Relationship of 24-hour blood pressure mean and variability to severity of target-organ damage in hypertension. J. Hypertens. 5 (1987) 93-98
42. Parati G., Mancia G., Rienzo M.D., Castiglioni P., Taylor J.A., and Studinger P. Point:counterpoint: cardiovascular variability is/is not an index of autonomic control of circulation. J. Appl. Physiol. 101 (2006) 676-682
43. Phillips J.K. Pathogenesis of hypertension in renal failure: role of the sympathetic nervous system and renal afferents. Clin. Exp. Pharmacol. Physiol. 32 (2005) 415-418
44. Phillips J., Hopwood D., Loxley R., Ghatora K., Coombes J., Tan Y., Harrison J., McKitrick D., Holobotvskyy V., Arnolda L., and Rangan G. Temporal relationship between renal cyst development, hypertension and cardiac hypertrophy in a new rat model of autosomal recessive polycystic kidney disease. Kidney Blood Press. Res. 30 (2007)
45. Platisa M.M., and Gal V. Reflection of heart rate regulation on linear and nonlinear heart rate variability measures. Physiol. Meas. 27 (2006) 145-154
46. Polak G., Strozecki P., Grzesk G., Manitius J., Grabczewska Z., and Przybyl R. Effect of parathormone on heart rate variability in hemodialysis patients. Auton. Neurosci. Basic Clin. 115 (2004) 94-98
47. Ponchon P., and Elghozi J.L. Contribution of the renin-angiotensin and kallikrein-kinin systems to short-term variability of blood pressure in two-kidney, one-clip hypertensive rats. Eur. J. Pharmacol. 297 (1996) 61-70
48. Ranpuria R., Hall M., Chan C.T., and Unruh M. Heart rate variability (HRV) in kidney failure: measurement and consequences of reduced HRV. Nephrol. Dial. Transplant. 23 (2008) 444-449
49. Rubinger D., Backenroth R., and Sapoznikov D. Restoration of baroreflex function in patients with end-stage renal disease after renal transplantation. Nephrol. Dial. Transplant. (2009) gfn732
50. Shan Z.Z., Dai S.M., and Su D.F. Relationship between baroreceptor reflex function and end-organ damage in spontaneously hypertensive rats. Am. J. Physiol. Heart Circ. Physiol. 277 (1999) H1200-H1206
51. Sleight P. The importance of the autonomic nervous system in health and disease. Aust. N.Z.J. Med. 27 (1997) 467-473
52. Solders G., Persson A., and Gutierrez A. Autonomic dysfunction in non-diabetic terminal uraemia. Acta Neurol. Scand. 71 (1985) 321-327
53. Souza H.C.D., Martins-Pinge M.C., Dias da Silva V.J., Borghi-Silva A., Gastaldi A.C., Blanco J.o.H.D., and Tezini G.C.S.V. Heart rate and arterial pressure variability in the experimental renovascular hypertension model in rats. Auton. Neurosci. Basic Clin. 139 (2008) 38-45
54. Stauss H.M. Heart rate variability. Am. J. Physiol. Regul. Integr. Comp. Physiol. 285 (2003) R927-R931
55. Stauss H.M. Identification of blood pressure control mechanisms by power spectral analysis. Clin. Exp. Pharmacol. Physiol. 34 (2007) 362-368
56. Steinberg A.A., Mars R.L., Goldman D.S., and Percy R.F. Effect of end-stage renal disease on decreased heart rate variability. Am. J. Cardiol. 82 (1998) 1156-1158 A1110
57. Studinger P., Lenard Z., Mersich B., Reusz G.S., and Kollai M. Determinants of baroreflex function in juvenile end-stage renal disease. Kidney Int. 69 (2006) 2236-2242
58. Su D.F., and Miao C.Y. Blood pressure variability and organ damage. Clin. Exp. Pharmacol. Physiol. 28 (2001) 709-715
59. Sweeney Jr. W.E., and Avner E.D. Molecular and cellular pathophysiology of autosomal recessive polycystic kidney disease (ARPKD). Cell Tissue Res. (2006)
60. Task Force. Heart rate variability: standards of measurement, physiological interpretation, and clinical use. European Society of Cardiology the North American Society of Pacing. Circulation 93 (1996) 1043-1065
61. Valvo E., Gammaro L., Tessitore N., Panzetta G., Lupo A., Loschiavo C., Oldrizzi L., Fabris A., Rugiu C., Ortalda V., et al. Hypertension of polycystic kidney disease: mechanisms and hemodynamic alterations. Am. J. Nephrol. 5 (1985) 176-181
62. VanNess J.M., Hinojosa-Laborde C., Craig T., and Haywood J.R. Effect of sinoaortic deafferentation on renal wrap hypertension. Hypertension 33 (1999) 476-481
63. Zerres K., Rudnik-Schoneborn S., Senderek J., Eggermann T., and Bergmann C. Autosomal recessive polycystic kidney disease (ARPKD). J. Nephrol. 16 (2003) 453-458