Altered Neural Processing of Threat in Alcohol-Dependent Men

Alcoholism: Clinical and Experimental Research

Volumn 37, Issue 12, 2013, Pages 2029-2038

  Yang, Hongyu ^a   Devous, Michael D ^b   Briggs, Richard W ^b   Spence, Jeffrey S ^b   Xiao, Hong ^c   Kreyling, Nicholas ^c   Adinoff, Bryon ^c,d  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d VA NORTH TEXAS HEALTH CARE SYSTEM   (United States)

Author keywords

Alcoholism; Anticipatory Anxiety; Emotional Stress; Functional Magnetic Resonance Imaging; Striatal Limbic Cortical System

Indexed keywords

ADULT; ALCOHOLISM; AMPLITUDE MODULATION; ANTERIOR CINGULATE; ANTICIPATORY ANXIETY; ARTICLE; BOLD SIGNAL; CLINICAL ARTICLE; CONDITIONING; CONTROLLED STUDY; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HIPPOCAMPUS; HUMAN; MALE; MIDDLE AGED; NERVE POTENTIAL; OCCIPITAL CORTEX; ORBITAL CORTEX; PARIETAL CORTEX; POSTERIOR CINGULATE; PREFRONTAL CORTEX; PRIORITY JOURNAL; STIMULUS RESPONSE;

ALCOHOLISM; ANTICIPATORY ANXIETY; EMOTIONAL STRESS; FUNCTIONAL MAGNETIC RESONANCE IMAGING; STRIATAL-LIMBIC-CORTICAL SYSTEM;

ALCOHOLISM; ANTICIPATION, PSYCHOLOGICAL; ANXIETY; CORPUS STRIATUM; EMOTIONS; GYRUS CINGULI; HUMANS; LIMBIC SYSTEM; MAGNETIC RESONANCE IMAGING; MALE; STRESS, PSYCHOLOGICAL;

EID: 84897054439     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/acer.12187     Document Type: Article

References (55)

1. Adinoff B, Best SE, Ye W, Williams MJ, Iranmenesh A (2010) Adrenocortical and pituitary glucocorticoid feedback in abstinent alcohol-dependent women. Alcohol Clin Exp Res 34:915-924.
2. Adinoff B, Junghanns K, Kiefer F, Krishnan-Sarin S (2005a) Suppression of the HPA axis stress-response: implications for relapse. Alcohol Clin Exp Res 29:1351-1355.
3. Adinoff B, Krebaum SR, Chandler PA, Ye W, Brown MB, Williams MJ (2005b) Dissection of hypothalamic-pituitary-adrenal axis pathology in 1-month-abstinent alcohol-dependent men, part 1: adrenocortical and pituitary glucocorticoid responsiveness. Alcohol Clin Exp Res 29:517-527.
4. Adinoff B, Krebaum SR, Chandler PA, Ye W, Brown MB, Williams MJ (2005c) Dissection of hypothalamic-pituitary-adrenal axis pathology in 1-month-abstinent alcohol-dependent men, part 2: response to ovine corticotropin-releasing factor and naloxone. Alcohol Clin Exp Res 29:528-537.
5. Adinoff B, Risher-Flowers D, De Jong J, Ravitz B, Bone GHA, Nutt DJ, Roehrich L, Martin PR, Linnoila M (1991) Disturbances of hypothalamic-pituitary-adrenal axis functioning during ethanol withdrawal in six men. Am J Psychiatry 148:1023-1025.
6. American Psychiatric Association (1994) Diagnostic and Statistical Manual of Mental Disorders. 4th ed. American Psychiatric Association, Washington, DC.
7. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J (1979) An inventory for measuring depression. Arch Gen Psychiatry 4:561-571.
8. Bishop S, Duncan J, Brett M, Lawrence AD (2004) Prefrontal cortical function and anxiety: controlling attention to threat-related stimuli. Nat Neurosci 7:184-188.
9. Brady KT, Sinha R (2005) Co-occurring mental and substance use disorders: the neurobiological effects of chronic stress. Am J Psychiatry 162:1483-1493.
10. Bush G, Luu P, Posner MI (2000) Cognitive and emotional influences in anterior cingulate cortex. Trends Cogn Sci 4:215-222.
11. Chaplin TM, Hong K, Bergquist K, Sinha R (2008) Gender differences in response to emotional stress: an assessment across subjective, behavioral, and physiological domains and relations to alcohol craving. Alcohol Clin Exp Res 32:1242-1250.
12. Chopra K, Tiwari V (2012) Alcoholic neuropathy: possible mechanisms and future treatment possibilities. Br J Clin Pharmacol 73:348-362.
13. Craig AD (2003) Interoception: the sense of the physiological condition of the body. Curr Opin Neurobiol 13:500-505.
14. Daughters SB, Richards JM, Gorka SM, Sinha R (2009) HPA axis response to psychological stress and treatment retention in residential substance abuse treatment: a prospective study. Drug Alcohol Depend 105:202-208.
15. Etkin A, Egner T, Kalisch R (2011) Emotional processing in anterior cingulate and medial prefrontal cortex. Trends Cogn Sci 15:85-93.
16. First MH, Spitzer RL, Gibbon M, Williams JBW (1996) Structured Clinical Interview for DSM-IV Axis I Disorders, Patient ed (SCID-I/P, Version 2.0). Biometrics Research Department, New York State Psychiatric Institute, New York, NY.
17. Gopinath K, Gandhi P, Goyal A, Jiang L, Fang Y, Ouyang L, Ganji S, Buhner D, Ringe W, Spence J, Biggs M, Briggs R, Haley R (2012) FMRI reveals abnormal central processing of sensory and pain stimuli in ill Gulf War veterans. Neurotoxicology 33:261-271.
18. Gopinath K, Ringe W, Goyal A, Carter K, Dinse HR, Haley R, Briggs R (2011) Striatal functional connectivity networks are modulated by fMRI resting state conditions. Neuroimage 54:380-388.
19. Greenfield SF, Manwani SG, Nargiso JE (2003) Epidemiology of substance use disorders in women. Obstet Gynecol Clin North Am 30:413-446.
20. Gusnard DA, Akbudak E, Shulman GL, Raichle ME (2001) Medial prefrontal cortex and self-referential mental activity: relation to a default mode of brain function. Proc Natl Acad Sci USA 98:4259-4264.
21. Hardie TL, Moss HB, Lynch KG (2008) Sex differences in the heritability of alcohol problems. Am J Addict 17:319-327.
22. Heilig M, Egli M, Crabbe JC, Becker HC (2010) Acute withdrawal, protracted abstinence and negative affect in alcoholism: are they linked? Addict Biol 15:169-184.
23. Heldestad V, Linder J, Sellersjo L, Nordh E (2010) Reproducibility and influence of test modality order on thermal perception and thermal pain thresholds in quantitative sensory testing. Clin Neurophysiol 121:1878-1885.
24. Jenkinson M, Bannister P, Brady M, Smith S (2002) Improved optimization for the robust and accurate linear registration and motion correction of brain images. Neuroimage 17:825-841.
25. Jenkinson M, Smith S (2001) A global optimisation method for robust affine registration of brain images. Med Image Anal 5:143-156.
26. Kim MJ, Chey J, Chung A, Bae S, Khang H, Ham B, Yoon SJ, Jeong DU, Lyoo IK (2008) Diminished rostral anterior cingulate activity in response to threat-related events in posttraumatic stress disorder. J Psychiatr Res 42:268-277.
27. LaBar KS, Gatenby JC, Gore JC, LeDoux JE, Phelps EA (1998) Human amygdala activation during conditioned fear acquisition and extinction: a mixed-trial fMRI study. Neuron 20:937-945.
28. Larson CL, Aronoff J, Sarinopoulos IC, Zhu DC (2009) Recognizing threat: a simple geometric shape activates neural circuitry for threat detection. J Cogn Neurosci 21:1523-1535.
29. Miller WR, Tonigan JS, Longabaugh R (1995) The Drinker Inventory of Consequences (DrInC): An Instrument for Assessing Adverse Consequences of Alcohol Abuse. National Institutes of Health, Rockville, MD.
30. Mobbs D, Petrovic P, Marchant JL, Hassabis D, Weiskopf N, Seymour B, Dolan RJ, Frith CD (2007) When fear is near: threat imminence elicits prefrontal-periaqueductal gray shifts in humans. Science 317:1079-1083.
31. Morris JS, Buchel C, Dolan RJ (2001) Parallel neural responses in amygdala subregions and sensory cortex during implicit fear conditioning. Neuroimage 13:1044-1052.
32. Ploghaus A, Tracey I, Gati JS, Clare S, Menon RS, Matthews PM, Rawlins JN (1999) Dissociating pain from its anticipation in the human brain. Science 284:1979-1981.
33. Pruessner JC, Dedovic K, Khalili-Mahani N, Engert V, Pruessner M, Buss C, Renwick R, Dagher A, Meaney MJ, Lupien S (2008) Deactivation of the limbic system during acute psychosocial stress: evidence from positron emission tomography and functional magnetic resonance imaging studies. Biol Psychiatry 63:234-240.
34. Pruessner JC, Dedovic K, Pruessner M, Lord C, Buss C, Collins L, Dagher A, Lupien SJ (2010) Stress regulation in the central nervous system: evidence from structural and functional neuroimaging studies in human populations-2008 Curt Richter Award Winner. Psychoneuroendocrinology 35:179-191.
35. Raichle ME, MacLeod AM, Snyder AZ, Powers WJ, Gusnard DA, Shulman GL (2001) A default mode of brain function. Proc Natl Acad Sci USA 98:676-682.
36. Rhudy JL, Meagher MW (2000) Fear and anxiety: divergent effects on human pain thresholds. Pain 84:65-75.
37. Sarinopoulos I, Grupe DW, Mackiewicz KL, Herrington JD, Lor M, Steege EE, Nitschke JB (2010) Uncertainty during anticipation modulates neural responses to aversion in human insula and amygdala. Cereb Cortex 20:929-940.
38. Schepis TS, Rao U, Yadav H, Adinoff B (2011) The limbic-hypothalamic-pituitary-adrenal axis and the development of alcohol use disorders in youth. Alcohol Clin Exp Res 35:595-605.
39. Schiller D, Levy I, Niv Y, LeDoux JE, Phelps EA (2008) From fear to safety and back: reversal of fear in the human brain. J Neurosci 28:11517-11525.
40. Sehlmeyer C, Schoning S, Zwitserlood P, Pfleiderer B, Kircher T, Arolt V, Konrad C (2009) Human fear conditioning and extinction in neuroimaging: a systematic review. PLoS ONE 4:e5865.
41. Seo D, Lacadie CM, Tuit K, Hong KI, Constable RT, Sinha R (2013) Disrupted ventromedial prefrontal function, alcohol craving, and subsequent relapse risk. JAMA Psychiatry 70:727-739.
42. Shin LM, Whalen PJ, Pitman RK, Bush G, Macklin ML, Lasko NB, Orr SP, McInerney SC, Rauch SL (2001) An fMRI study of anterior cingulate function in posttraumatic stress disorder. Biol Psychiatry 50:932-942.
43. Sinha R, Fox HC, Hong KI, Hansen J, Tuit K, Kreek MJ (2011) Effects of adrenal sensitivity, stress- and cue-induced craving, and anxiety on subsequent alcohol relapse and treatment outcomes. Arch Gen Psychiatry 68:942-952.
44. Sinha R, Li CS (2007) Imaging stress- and cue-induced drug and alcohol craving: association with relapse and clinical implications. Drug Alcohol Rev 26:25-31.
45. Smith SM (2002) Fast robust automated brain extraction. Hum Brain Mapp 17:143-155.
46. Sobell MB, Sobell LC (1978) Behavioral Treatment of Alcohol Problems. Plenum Press, New York, NY.
47. Somerville LH, Whalen PJ, Kelley WM (2010) Human bed nucleus of the stria terminalis indexes hypervigilant threat monitoring. Biol Psychiatry 68:416-424.
48. Speilberger CD (1971) Trait-state anxiety and motor behavior. J Mot Behav 3:265-279.
49. Sripada RK, King AP, Welsh RC, Garfinkel SN, Wang X, Sripada CS, Liberzon I (2012) Neural dysregulation in posttraumatic stress disorder: evidence for disrupted equilibrium between salience and default mode brain networks. Psychosom Med 74:904-911.
50. Straube T, Schmidt S, Weiss T, Mentzel HJ, Miltner WH (2009) Dynamic activation of the anterior cingulate cortex during anticipatory anxiety. Neuroimage 44:975-981.
51. Verdejo-Garcia A, Clark L, Dunn BD (2012) The role of interoception in addiction: a critical review. Neurosci Biobehav Rev 36:1857-1869.
52. Wang J, Korczykowski M, Rao H, Fan Y, Pluta J, Gur RC, McEwen BS, Detre JA (2007) Gender difference in neural response to psychological stress. Soc Cogn Affect Neurosci 2:227-239.
53. Wang J, Rao H, Wetmore GS, Furlan PM, Korczykowski M, Dinges DF, Detre JA (2005) Perfusion functional MRI reveals cerebral blood flow pattern under psychological stress. Proc Natl Acad Sci USA 102:17804-17809.
54. Worsley KJ (2001) Statistical analysis of activation image, in Functional MRI: An Introduction to Methods, Functional MRI: An Introduction to Methods (Jezzard P, Matthews PM, Smith SM, eds), pp 251-270. Oxford University Press, Oxford.
55. Yang H, Spence JS, Devous MD Sr, Briggs RW, Goyal A, Xiao H, Yadav H, Adinoff B (2012) Striatal-limbic activation is associated with intensity of anticipatory anxiety. Psychiatry Res 204:123-131.