The role of mesenchymal stem cells in bone repair and regeneration

European Journal of Orthopaedic Surgery and Traumatology

Volumn 24, Issue 3, 2014, Pages 257-262

  Šponer, Pavel ^a,b   Kučera, Tomáš ^a,b   Diaz Garcia, Daniel ^a   Filip, Stanislav ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

^b UNIVERSITY HOSPITAL HRADEC KRALOVE   (Czech Republic)

Author keywords

Bone healing; Calcium phosphate; Mesenchymal stem cells; Scaffold

Indexed keywords

VASCULAR CELL ADHESION MOLECULE 1;

ANTIGENICITY; BIOMECHANICS; BONE CONDUCTION; BONE REGENERATION; BONE REMODELING; CARTILAGE CELL; CELL ADHESION; CELL CULTURE; CELL DIFFERENTIATION; CELL FUNCTION; CELL POPULATION; CELL PROLIFERATION; HEMATOPOIETIC STEM CELL; HUMAN; MEDICAL RESEARCH; MESENCHYMAL STEM CELL; NONHUMAN; POROSITY; PRIORITY JOURNAL; REGENERATIVE MEDICINE; REVIEW; UMBILICAL CORD BLOOD; XENOGRAFT;

BONE DISEASES; BONE REGENERATION; CELL DIFFERENTIATION; HUMANS; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; TISSUE ENGINEERING;

EID: 84897052353     PISSN: 16338065     EISSN: 14321068     Source Type: Journal    
DOI: 10.1007/s00590-013-1328-5     Document Type: Review

References (43)

1. Agacayak S, Gulsun B, Ucan MC, Karaoz E, Nergiz Y (2012) Effects of mesenchymal stem cells in critical size bone defect. Eur Rev Pharmacol Sci 16:679-686
2. Greenwald AS, Boden SD, Goldberg VM, Khan Y, Laurencin CT, Rosier RN (2001) Bone-graft substitutes: facts, fictions, and applications. J Bone Joint Surg [Am] 83-A:S98-S103
3. Urist MR, Silverman BF, Buring K, Dubuc FL, Rosenberg JM (1967) The bone induction principle. Clin Orthop 53:243-283
4. Mizuno D, Agata H, Furue H, Narita Y, Watanabe N, Ishii Y, Ueda M, Tojo A, Kagami H (2010) Limited but heterogeneous osteogenic response of human bone marrow mesenchymal stem cells to bone morphogenetic protein-2 and serum. Growth Factors 28:34-43
5. Šponer P, Urban K, Kučera T, Kohout A, Brtková J, Knížek J (2011) The use of interconnected β-tricalcium phosphate as bone substitute after curettage of benign bone tumours. Eur J Orthop Surg Traumatol 21:235-241
6. Wenz B, Leech B, Horst M (2001) Analysis of the risk of transmitting bovine spongiform encephalopathy though bone grafts derived from bovine bone. Biomaterials 22:1599-1606 (Pubitemid 32551909)
7. Khan Y, Yaszemski MJ, Mikos AG, Laurencin CT (2008) Tissue engineering of bone: material and matrix consideration. J Bone Joint Surg [Am] 90-A:S36-S42
8. Hak DJ (2007) The use of osteoconductive bone graft substitutes in orthopaedic trauma. J Am Acad Orthop Surg 15:525-536
9. Hench LL, Polak JM (2002) Third-generation biomedical materials. Science 295:1014-1017
10. Mankani MH, Kuznetsov SA, Fowler B, Kingman A, Gehron Robey P (2001) In vivo bone formation by human bone marrow stromal cells: effect of carrier particle size and shape. Biotechnol Bioeng 72:96-107 (Pubitemid 32085898)
11. Kasten P, Vogel J, Luginbuhl R, Niemeyer P, Tonak M, Lorenz H, Helbig L, Weiss S, Fellenberg J, Leo A, Simank H-G, Richter W (2005) Ectopic bone formation associated with mesenchymal stem cells in a resorbable calcium deficient hydroxyapatite carrier. Biomaterials 26:5879-5889 (Pubitemid 40798279)
12. Kasten P, Beyen I, Niemeyer P, Luginbuhl R, Bohner M, Richter W (2008) Porosity and pore size of β-tricalcium phosphate scaffold can influence protein production and osteogenic differentiation of human mesenchymal stem cells: an in vitro and in vivo study. Acta Biomater 4:1904-1915
13. Hilfiker A, Kasper C, Hass R, Haverich A (2011) Mesenchymal stem cells and progenitor cells in connective tissue engineering and regenerative medicine: is there a future for transplantation? Langenbecks Arch Surg 396:489-497
14. Méndez-Ferrer S, Michurina TV, Ferraro F, Mazloom AR, Macarthur BD, Lira SA, Scadden DT, Ma'ayan A, Enikolopov GN, Frenette PS (2010) Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature 466:829-834
15. Hass R, Kasper C, Böhm S, Jacobs R (2011) Different populations and sources of human mesenchymal stem cells (MSC): a comparison of adult and neonatal tissue-derived MSC. Cell Commun Signal 9:1-14
16. Ling L, Nurcombe V, Cool SM (2009) Wnt signaling controls the fate of mesenchymal stem cells. Gene 433:1-7
17. Peng L, Jia Z, Yin X, Zhang X, Liu Y, Chen P, Ma K, Zhou C (2008) Comparative analysis of mesenchymal stem cells from bone marrow, cartilage, and adipose tissue. Stem Cells Dev 17:761-773
18. Majore I, Moretti P, Stahl F, Hass R, Kasper C (2011) Growth and differentiation properties of mesenchymal stromal cell populations derived from whole human umbilical cord. Stem Cell Rev Rep 7:17-31
19. Mobasheri A, Csaki C, Clutterbuck AL, Rahmanzadeh M, Shakibaei M (2009) Mesenchymal stem cells in connective tissue engineering and regenerative medicine: applications in cartilage repair and osteoarthritis therapy. Histol Histopathol 24:347-366
20. Dominici M, Le Blanc K, Mueller I, Slaper-Cortenbach I, Marini F, Krause D, Deans R, Keating A, Prockop D, Horwitz E (2006) Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for cellular therapy position statement. Cytotherapy 8:315-317 (Pubitemid 44269669)
21. Qian H, Le Blanc K, Sigvardsson M (2012) Primary mesenchymal stem and progenitor cells from bone marrow lack expression of CD44 protein. J Biol Chem 287:25795-25807
22. Ren G, Zhao X, Zhang L, Zhang J, L'Huillier A, Ling W, Roberts AI, Le AD, Shi S, Shao C, Shi Y (2010) Inflammatory cytokine-induced intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in mesenchymal stem cells are critical for immunosuppression. J Immunol 184:2321-2328
23. Lin G, Liu G, Banie L, Wang G, Ning H, Lue TF, Lin CS (2011) Tissue distribution of mesenchymal stem cell marker Stro-1. Stem Cells Dev 20:1747-1752
24. Bruder SP, Kurth AA, Shea M, Hayes WC, Jaiswal N, Kadiyala S (1998) Bone regeneration by implantation of purified, culture-expanded human mesenchymal stem cells. J Orthop Res 16:155-162 (Pubitemid 28249153)
25. Kon E, Muraglia A, Cosi A, Bianco P, Marcacci M, Martin I, Boyde A, Ruspantini I, Chistolini P, Rocca M, Gardino R, Cancedda R, Quarto R (2000) Autologous bone marrow stromal cells loaded onto porous hydroxyapatite ceramic accelerate bone repair in critical-size defects of sheep long bones. J Biomed Mat Res 49:328-337 (Pubitemid 30030478)
26. Warren S, Nacamuli RK, Song HJ, Longaker MT (2004) Tissue-engineered bone using mesenchymal stem cells and a biodegradable scaffold. J Craniofac Surg 15:34-37
27. Viateau V, Guillemin G, Bousson V, Oudina K, Hannouche D, Sedel L, Logeart-Avramoglou D, Petite H (2007) Long-bone critical-size defects treated with tissue-engineered grafts: a study on Wheel. J Orthop Res 25:741-749 (Pubitemid 46831882)
28. Herzog K (1951) Verlangerung osteotomie unter Verwendung des Perkutan gezielt verriegelten Markangels. Unfallheikunde 42:26
29. Connolly JF (1995) Injectable bone marrow preparations to stimulate osteogenic repair. Clin Orthop 313:8-18
30. Hernigou P, Poignard A, Beaujean F, Rouard H (2005) Percutaneous autologous bone-marrow grafting for nonunions: influence of the number and concentration of progenitor cells. J Bone Joint Surg [Am] 87-A:1430-1437 (Pubitemid 40917741)
31. Cuomo AV, Virk M, Petrigliano F, Morgan EF, Lieberman JR (2009) Mesenchymal stem cell concentration and bone repair: potential pitfalls from bench to bedside. J Bone Joint Surg [Am] 91-A:1073-1083
32. Wongchuensoontorn C, Liebehenschel N, Schwarz U et al (2009) Application of a new chair-side method for the harvest of mesenchymal stem cells in a patient with nonunion of a fracture of the atrophic mandible - a case report. J Craniomaxillofac Surg 37:155-161
33. Devine SM, Bartholomew AM, Mahmud N et al (2001) Mesenchymal stem cells are capable of homing to the bone marrow of non-human primates following systemic infusion. Exp Hematom 29:244-255 (Pubitemid 32112325)
34. Liu L, Sun Z, Chen B et al (2006) Ex vivo expansion and in vivo infusion of bone marrow-derived FIk-1+ CD31- CD34- mesenchymal stem cells: feasibility and safety from monkey to human. Stem Cells Dev 15:349-357 (Pubitemid 44100013)
35. Horwitz EM, Gordon PL, Koo WK et al (2002) Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: implications for cell therapy of bone. Proc Natl Acad Sci USA 99:8932-8937 (Pubitemid 34693661)
36. Schrepter S, Deuse T, Reichenspurner H et al (2007) Stem cell transplantation: the lung barrier. Transplant Proc 39:573-576 (Pubitemid 46386222)
37. Quarto R, Masrogiacomo M, Cancedda R et al (2001) Repair of large bone defects with the use of autologous bone marrow stroma cells. N Engl J Med 344:385-386 (Pubitemid 32107654)
38. Marcacci M, Kon E, Moukhachev V et al (2007) Stem cells associated with macroporous bioceramics for long bone repair: 6- to 7-year outcome of a pilot clinical study. Tissue Eng 13:947-955 (Pubitemid 46870419)
39. Kawate K, Tajina H, Ohgushi H et al (2006) Tissue-engineered approach for the treatment of steroid-induced osteonecrosis of the femoral head: transplantation of autologous mesenchymal stem cell cultured with beta-tricalcium phosphate ceramics and free vascularized fibula. Artif Organs 30:952-960
40. Muschler GF, Matsukara Y, Nitto H et al (2005) Selective retention of bone marrow-derived cells to enhance spinal vision. Clin Orthop 432:242-251 (Pubitemid 40316187)
41. Gamradt SC, Lieberman JR (2004) Genetic modification of stem cells to enhance bone repair. Ann Biomed Eng 32:136-147
42. Gamradt SC, Abe N, Bahamonde ME et al (2006) Tracking expression of virally mediated BMP-2 in gene therapy for bone repair. Clin Orthop 450:238-245 (Pubitemid 44342141)
43. Lin L, Shen Q, Wei X et al (2009) Comparison of osteogenic potentials of BMP4 transduced stem cells from autologous bone marrow and fat tissue in a rabbit model of calvarial defects. Calcif Tissue Int 85:55-65