Human adipose-derived stem cells modified by HIF-1α accelerate the recovery of cisplatin-induced acute renal injury in vitro

Biotechnology Letters

Volumn 36, Issue 3, 2014, Pages 667-676

  Wang, WeiWei ^a   Wang, Wei ^b   Jiang, Yan ^b   Li, Zezheng ^b   Cheng, Jin ^a   Liu, Nanmei ^a   Han, GuoFeng ^a   Lu, Shi ^a   Zhang, JinYuan ^a  

^a Jimin Hospital   (China)

^b SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Acute kidney injury; Cisplatin; Human adipose derived stem cells; Human kidney 2 cells; Hypoxia inducible factor 1 ; Renal injury

Indexed keywords

CELL ENGINEERING; CYTOLOGY; GENE EXPRESSION; PLATINUM COMPOUNDS; STEM CELLS; VECTORS;

ACUTE KIDNEY INJURY; ADIPOSE DERIVED STEM CELLS; CIS-PLATIN; HEME OXYGENASE-1; HYPOXIA-INDUCIBLE FACTOR 1; RENAL FUNCTIONS; RENAL INJURY; VASCULAR ENDOTHELIAL GROWTH FACTOR;

MOLECULAR BIOLOGY;

LENTIVIRUS;

CISPLATIN; HEME OXYGENASE 1; HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; RECOMBINANT PROTEIN; VASCULOTROPIN A;

ACUTE KIDNEY FAILURE; APOPTOSIS; ARTICLE; CELL LINE; CELL TRANSPLANTATION; EPITHELIUM CELL; GENE VECTOR; GENETICS; HUMAN; IN VITRO STUDY; LENTIVIRINAE; METABOLISM; METHODOLOGY; PHYSIOLOGY; STEM CELL;

ACUTE KIDNEY INJURY; APOPTOSIS; CELL LINE; CELL TRANSPLANTATION; CISPLATIN; EPITHELIAL CELLS; GENETIC VECTORS; HEME OXYGENASE-1; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LENTIVIRUS; RECOMBINANT PROTEINS; STEM CELLS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84897047561     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-013-1389-x     Document Type: Article

References (17)

1. Ahn JM, You SJ, Lee YM, Oh SW, Ahn SY, Kim S, Chin HJ, Chae DW, Na KY (2012) Hypoxia-inducible factor activation protects the kidney from gentamicin-induced acute injury. PLoS One 7: e48952.
2. Chung BH, Lim SW, Doh KC, Piao SG, Heo SB, Yang CW (2013) Human adipose tissue derived mesenchymal stem cells aggravate chronic cyclosporin nephrotoxicity by the induction of oxidative stress. PLoS One 8: e59693.
3. Colazzo F, Chester AH, Taylor PM, Yacoub MH (2010) Induction of mesenchymal to endothelial transformation of adipose-derived stem cells. J Heart Valve Dis 19: 736-744.
4. Huang LE, Gu J, Schau M, Bunn HF (1998) Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway. Proc Natl Acad Sci USA 95: 7987-7992.
5. Jamadarkhana P, Chaudhary A, Chhipa L, Dubey A, Mohanan A, Gupta R, Deshpande S (2012) Treatment with a novel hypoxia-inducible factor hydroxylase inhibitor (TRC160334) ameliorates ischemic acute kidney injury. Am J Nephrol 36: 208-218.
6. Kim JH, Park DJ, Yun JC, Jung MH, Yeo HD, Kim HJ, Kim DW, Yang JI, Lee GW, Jeong SH, Roh GS, Chang SH (2012) Human adipose tissue-derived mesenchymal stem cells protect kidneys from cisplatin nephrotoxicity in rats. Am J Physiol Renal Physiol 302: F1141-F1150.
7. Lu LH, Oh DJ, Dursun B, He Z, Hoke TS, Faubel S, Edelstein CL (2008) Increased macrophage infiltration and fractalkine expression in cisplatin-induced acute renal failure in mice. J Pharmacol Exp Ther 324: 111-117.
8. Rosenberger C, Griethe W, Gruber G, Wiesener M, Frei U, Bachmann S, Eckardt KU (2003) Cellular responses to hypoxia after renal segmental infarction. Kidney Int 64: 874-886.
9. Tadagavadi RK, Reeves WB (2010) Endogenous IL-10 attenuates cisplatin nephrotoxicity: role of dendritic cells. J Immunol 185: 4904-4911.
10. Tögel F, Zhang P, Hu Z, Westenfelder C (2009) VEGF is a mediator of the renoprotective effects of multipotent marrow stromal cells in acute kidney injury. J Cell Mol Med 13: 2109-2114.
11. Wang W, Zhang J (2008) Induction of renoprotective gene expression by hypoxia-inducible transcription factor-1alpha ameliorates renal damage. Med Hypotheses 70: 948-950.
12. Weidemann A, Bernhardt WM, Klanke B, Daniel C, Buchholz B, Campean V, Amann K, Warnecke C, Wiesener MS, Eckardt KU, Willam C (2008) HIF activation protects from acute kidney injury. J Am Soc Nephrol 19: 486-494.
13. Witkowska-Zimny M, Walenko K (2011) Stem cells from adipose tissue. Cell Mol Biol Lett 16: 236-257.
14. Xishan Z, Baoxin H, Xinna Z, Jun R (2013) Comparison of the effects of human adipose and bone marrow mesenchymal stem cells on T lymphocytes. Cell Biol Int 37: 11-18.
15. Zarjou A, Agarwal A (2012) Heme oxygenase-1 as a target for TGF-β in kidney disease. Semin Nephrol 32: 277-286.
16. Zarjou A, Kim J, Traylor AM, Sanders PW, Balla J, Agarwal A, Curtis LM (2011) Paracrine effects of mesenchymal stem cells in cisplatin-induced renal injury require heme oxygenase-1. Am J Physiol Renal Physiol 300: F254-F262.
17. Zheng Y, Lu M, Ma L, Zhang S, Qiu M, Wang Y (2013) Osthole ameliorates renal ischemia-reperfusion injury in rats. J Surg Res 183: 347-354.