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Volumn 9, Issue 3, 2014, Pages 257-265

Behçet's syndrome pathophysiology and potential therapeutic targets

Author keywords

Anti TNF ; Beh et syndrome pathophysiology; Beh et treatment; Biologic therapy; IL 1 blocking agents

Indexed keywords

BEHCET SYNDROME; HUMAN; MOLECULARLY TARGETED THERAPY; PATHOPHYSIOLOGY;

EID: 84897023712     PISSN: 18280447     EISSN: 19709366     Source Type: Journal    
DOI: 10.1007/s11739-013-1036-5     Document Type: Review
Times cited : (62)

References (74)
  • 2
    • 84856899165 scopus 로고    scopus 로고
    • HLA-B*51 and Behçet disease
    • Gul A, Ohno S (2012) HLA-B*51 and Behçet disease. Ocular Immunol Inflamm 20: 37-43.
    • (2012) Ocular Immunol Inflamm , vol.20 , pp. 37-43
    • Gul, A.1    Ohno, S.2
  • 3
    • 0033185755 scopus 로고    scopus 로고
    • Behçet's disease, the Silk Road and HLA-B51: historical and geographical perspectives
    • Verity DH, Marr JE, Ohno S, Wallace GR, Stanford MR (1999) Behçet's disease, the Silk Road and HLA-B51: historical and geographical perspectives. Tissue Antigens 54: 213-220.
    • (1999) Tissue Antigens , vol.54 , pp. 213-220
    • Verity, D.H.1    Marr, J.E.2    Ohno, S.3    Wallace, G.R.4    Stanford, M.R.5
  • 9
    • 0023819452 scopus 로고
    • Induction of Behçet's disease symptoms after dental treatment and streptococcal antigen skin test
    • Mizushima Y, Matsuda T, Hoshi K, Ohno S (1988) Induction of Behçet's disease symptoms after dental treatment and streptococcal antigen skin test. J Rheumatol 15: 1029-1030.
    • (1988) J Rheumatol , vol.15 , pp. 1029-1030
    • Mizushima, Y.1    Matsuda, T.2    Hoshi, K.3    Ohno, S.4
  • 10
    • 70350156465 scopus 로고    scopus 로고
    • Association of salivary S. mutans colonisation and mannose-binding lectin deficiency with gender in Behçet's disease
    • Mumcu G, Inanc N, Aydin SZ, Ergun T, Direskeneli H (2009) Association of salivary S. mutans colonisation and mannose-binding lectin deficiency with gender in Behçet's disease. Clin Exp Rheumatol 27: S32-S36.
    • (2009) Clin Exp Rheumatol , vol.27
    • Mumcu, G.1    Inanc, N.2    Aydin, S.Z.3    Ergun, T.4    Direskeneli, H.5
  • 13
    • 0024337709 scopus 로고
    • Skin hypersensitivity to streptococcal antigens and the induction of systemic symptoms by the antigens in Behçet's disease-a multicenter study
    • The Behçet's Disease Research Committee of Japan
    • The Behçet's Disease Research Committee of Japan (1989) Skin hypersensitivity to streptococcal antigens and the induction of systemic symptoms by the antigens in Behçet's disease-a multicenter study. J Rheumatol 16: 506-511.
    • (1989) J Rheumatol , vol.16 , pp. 506-511
  • 14
    • 79958185441 scopus 로고    scopus 로고
    • Skin prick test with self-saliva in patients with oral aphthoses: a diagnostic pathergy for Behçet's disease and recurrent aphthosis
    • Togashi A, Saito S, Kaneko F, Nakamura K, Oyama N (2011) Skin prick test with self-saliva in patients with oral aphthoses: a diagnostic pathergy for Behçet's disease and recurrent aphthosis. Inflamm Allergy Drug Targets 10(3): 164-170.
    • (2011) Inflamm Allergy Drug Targets , vol.10 , Issue.3 , pp. 164-170
    • Togashi, A.1    Saito, S.2    Kaneko, F.3    Nakamura, K.4    Oyama, N.5
  • 16
    • 0030897029 scopus 로고    scopus 로고
    • The role of heat shock protein, microbial and autoimmune agents in the aetiology of Behçet's disease
    • Lehner T (1997) The role of heat shock protein, microbial and autoimmune agents in the aetiology of Behçet's disease. Int Rev Immunol 14: 21-32.
    • (1997) Int Rev Immunol , vol.14 , pp. 21-32
    • Lehner, T.1
  • 19
    • 52649127924 scopus 로고    scopus 로고
    • The role of streptococcal hypersensitivity in the pathogenesis of Behçet's disease
    • Kaneko F, Oyama N, Yanagihori H, Isogai E, Yokota K, Oguma K (2008) The role of streptococcal hypersensitivity in the pathogenesis of Behçet's disease. Eur J Dermatol 18: 489-498.
    • (2008) Eur J Dermatol , vol.18 , pp. 489-498
    • Kaneko, F.1    Oyama, N.2    Yanagihori, H.3    Isogai, E.4    Yokota, K.5    Oguma, K.6
  • 20
    • 33845527151 scopus 로고    scopus 로고
    • The role of heat shock protein 60, vascular endothelial growth factor and antiphospholipid antibodies in Behçet disease
    • Shaker O, Ay El-Deen MA, El Hadidi H, Grace BD, El Sherif H, Abdel Halim A (2007) The role of heat shock protein 60, vascular endothelial growth factor and antiphospholipid antibodies in Behçet disease. Br J Dermatol 156: 32-37.
    • (2007) Br J Dermatol , vol.156 , pp. 32-37
    • Shaker, O.1    Ay El-Deen, M.A.2    El Hadidi, H.3    Grace, B.D.4    El Sherif, H.5    Abdel Halim, A.6
  • 21
    • 0028337345 scopus 로고
    • Fine antigen specificity of human gamma delta T cell lines (V gamma 9 +) established by repetitive stimulation with a serotype (KTH-1) of a gram-positive bacterium, Streptococcus sanguis
    • Mochizuki M, Suzuki N, Takeno M, Nagafuchi H, Harada T, Kaneoka H, Yamashita N, Hirayama K, Nakajima T, Mizushima Y (1994) Fine antigen specificity of human gamma delta T cell lines (V gamma 9 +) established by repetitive stimulation with a serotype (KTH-1) of a gram-positive bacterium, Streptococcus sanguis. Eur J Immunol 24: 1536-1543.
    • (1994) Eur J Immunol , vol.24 , pp. 1536-1543
    • Mochizuki, M.1    Suzuki, N.2    Takeno, M.3    Nagafuchi, H.4    Harada, T.5    Kaneoka, H.6    Yamashita, N.7    Hirayama, K.8    Nakajima, T.9    Mizushima, Y.10
  • 22
    • 0037207955 scopus 로고    scopus 로고
    • Expansion of gammadelta T-cells in Behçet's disease: role of disease activity and microbial flora in oral ulcers
    • Bank I, Duvdevani M, Livneh A (2003) Expansion of gammadelta T-cells in Behçet's disease: role of disease activity and microbial flora in oral ulcers. J Lab Clin Med 141: 33-40.
    • (2003) J Lab Clin Med , vol.141 , pp. 33-40
    • Bank, I.1    Duvdevani, M.2    Livneh, A.3
  • 23
    • 0026605108 scopus 로고
    • Streptococcal related antigens stimulate production of IL-6 and interferon-gamma by T cells from patients with Behçet's disease
    • Hirohata S, Oka H, Mizushima Y (1992) Streptococcal related antigens stimulate production of IL-6 and interferon-gamma by T cells from patients with Behçet's disease. Cell Immunol 140: 410-419.
    • (1992) Cell Immunol , vol.140 , pp. 410-419
    • Hirohata, S.1    Oka, H.2    Mizushima, Y.3
  • 24
    • 33847129168 scopus 로고    scopus 로고
    • Immunopathogenesis of Behçet's disease with special emphasize on the possible role of antigen presenting cells
    • Pay S, Simşek I, Erdem H, Dinç A (2007) Immunopathogenesis of Behçet's disease with special emphasize on the possible role of antigen presenting cells. Rheumatol Int 27: 417-424.
    • (2007) Rheumatol Int , vol.27 , pp. 417-424
    • Pay, S.1    Simşek, I.2    Erdem, H.3    Dinç, A.4
  • 25
    • 84864389634 scopus 로고    scopus 로고
    • Cytokines and Behcet's disease
    • Zhou ZY, Chen SL, Lu Y (2012) Cytokines and Behcet's disease. Autoimmun Rev 11: 699-704.
    • (2012) Autoimmun Rev , vol.11 , pp. 699-704
    • Zhou, Z.Y.1    Chen, S.L.2    Lu, Y.3
  • 28
    • 84861479850 scopus 로고    scopus 로고
    • Behcet's disease and genes within the major histocompatibility complex region
    • Song YW, Kang EH (2012) Behcet's disease and genes within the major histocompatibility complex region. Mod Rheumatol 22: 178-185.
    • (2012) Mod Rheumatol , vol.22 , pp. 178-185
    • Song, Y.W.1    Kang, E.H.2
  • 30
    • 24344490821 scopus 로고    scopus 로고
    • Nitric oxide, lipid peroxidation and antioxidant defence system in patients with active or inactive Behçet's disease
    • Buldanlioglu S, Turkmen S, Ayabakan HB, Yenice N, Vardar M, Dogan S, Mercan E (2005) Nitric oxide, lipid peroxidation and antioxidant defence system in patients with active or inactive Behçet's disease. Br J Dermatol 153: 526-530.
    • (2005) Br J Dermatol , vol.153 , pp. 526-530
    • Buldanlioglu, S.1    Turkmen, S.2    Ayabakan, H.B.3    Yenice, N.4    Vardar, M.5    Dogan, S.6    Mercan, E.7
  • 31
    • 84873411673 scopus 로고    scopus 로고
    • Clinical targeting of the TNF and TNFR superfamilies
    • Croft M, Benedict CA, Ware CF (2013) Clinical targeting of the TNF and TNFR superfamilies. Nat Rev Drug Discov 12(2): 147-168.
    • (2013) Nat Rev Drug Discov , vol.12 , Issue.2 , pp. 147-168
    • Croft, M.1    Benedict, C.A.2    Ware, C.F.3
  • 32
    • 0027740303 scopus 로고
    • Overproduction of monocyte derived tumor necrosis factor alpha, interleukin (IL) 6, IL-8 and increased neutrophil superoxide generation in Behçet's disease. A comparative study with familial Mediterranean fever and healthy subjects
    • Mege JL, Dilsen N, Sanguedolce V, Gul A, Bongrand P, Roux H, Ocal L, Inanç M, Capo C (1993) Overproduction of monocyte derived tumor necrosis factor alpha, interleukin (IL) 6, IL-8 and increased neutrophil superoxide generation in Behçet's disease. A comparative study with familial Mediterranean fever and healthy subjects. J Rheumatol 20: 1544-1549.
    • (1993) J Rheumatol , vol.20 , pp. 1544-1549
    • Mege, J.L.1    Dilsen, N.2    Sanguedolce, V.3    Gul, A.4    Bongrand, P.5    Roux, H.6    Ocal, L.7    Inanç, M.8    Capo, C.9
  • 33
    • 2342511636 scopus 로고    scopus 로고
    • Vgamma9/Vdelta2 T lymphocytes in Italian patients with Behçet's disease: evidence for expansion, and tumour necrosis factor receptor II and interleukin-12 receptor beta1 expression in active disease
    • Triolo G, Accardo-Palumbo A, Dieli F, Ciccia F, Ferrante A, Giardina E, Sano CD, Licata G (2003) Vgamma9/Vdelta2 T lymphocytes in Italian patients with Behçet's disease: evidence for expansion, and tumour necrosis factor receptor II and interleukin-12 receptor beta1 expression in active disease. Arthritis Res Ther 5: R262-R268.
    • (2003) Arthritis Res Ther , vol.5
    • Triolo, G.1    Accardo-Palumbo, A.2    Dieli, F.3    Ciccia, F.4    Ferrante, A.5    Giardina, E.6    Sano, C.D.7    Licata, G.8
  • 34
    • 33646773993 scopus 로고    scopus 로고
    • Diversity of gammadelta T cells in patients with Behçet's disease is indicative of polyclonal activation
    • Freysdottir J, Hussain L, Farmer I, Lau SH, Fortune F (2006) Diversity of gammadelta T cells in patients with Behçet's disease is indicative of polyclonal activation. Oral Dis 12: 271-277.
    • (2006) Oral Dis , vol.12 , pp. 271-277
    • Freysdottir, J.1    Hussain, L.2    Farmer, I.3    Lau, S.H.4    Fortune, F.5
  • 35
    • 77953013515 scopus 로고    scopus 로고
    • Phenotype and functional changes of Vgamma9/Vdelta2 T lymphocytes in Behçet's disease and the effect of infliximab on Vgamma9/Vdelta2 T cell expansion, activation and cytotoxicity
    • Accardo-Palumbo A, Giardina AR, Ciccia F, Ferrante A, Principato A, Impastato R, Giardina E, Triolo G (2010) Phenotype and functional changes of Vgamma9/Vdelta2 T lymphocytes in Behçet's disease and the effect of infliximab on Vgamma9/Vdelta2 T cell expansion, activation and cytotoxicity. Arthritis Res Ther 12: R109.
    • (2010) Arthritis Res Ther , vol.12
    • Accardo-Palumbo, A.1    Giardina, A.R.2    Ciccia, F.3    Ferrante, A.4    Principato, A.5    Impastato, R.6    Giardina, E.7    Triolo, G.8
  • 37
    • 84866236509 scopus 로고    scopus 로고
    • Development of immunopathogenesis strategies to treat Behçet's disease
    • Köse O (2012) Development of immunopathogenesis strategies to treat Behçet's disease. Patholog Res Int 2012: 261989.
    • (2012) Patholog Res Int , vol.2012 , pp. 261989
    • Köse, O.1
  • 40
    • 78751598002 scopus 로고    scopus 로고
    • One year study of efficacy and safety of infliximab in the treatment of patients with ocular and neurological Behçet's disease refractory to standard immunosuppressive drugs
    • Giardina A, Ferrante A, Ciccia F, Vadalà M, Giardina E, Triolo G (2011) One year study of efficacy and safety of infliximab in the treatment of patients with ocular and neurological Behçet's disease refractory to standard immunosuppressive drugs. Rheumatol Int 31: 33-37.
    • (2011) Rheumatol Int , vol.31 , pp. 33-37
    • Giardina, A.1    Ferrante, A.2    Ciccia, F.3    Vadalà, M.4    Giardina, E.5    Triolo, G.6
  • 44
    • 84864545087 scopus 로고    scopus 로고
    • Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
    • Dinarello CA, Simon A, van der Meer JW (2012) Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases. Nat Rev Drug Discov 11(8): 633-652.
    • (2012) Nat Rev Drug Discov , vol.11 , Issue.8 , pp. 633-652
    • Dinarello, C.A.1    Simon, A.2    van der Meer, J.W.3
  • 45
    • 0025066668 scopus 로고
    • Production of TNF-alpha and IL-1 in active Behçet's disease
    • Hamzaoui K, Hamza M, Ayed K (1990) Production of TNF-alpha and IL-1 in active Behçet's disease. J Rheumatol 17(10): 1428-1429.
    • (1990) J Rheumatol , vol.17 , Issue.10 , pp. 1428-1429
    • Hamzaoui, K.1    Hamza, M.2    Ayed, K.3
  • 46
    • 33645865276 scopus 로고    scopus 로고
    • Synovial proinflammatory cytokines and their correlation with matrixmetalloproteinase-3 expression in Behçet's disease. Does interleukin-1b play a major role in Behçet's synovitis?
    • Pay S, Erdem H, Pekel A, Simsek I, Musabak U, Sengul A, Dinc A (2006) Synovial proinflammatory cytokines and their correlation with matrixmetalloproteinase-3 expression in Behçet's disease. Does interleukin-1b play a major role in Behçet's synovitis? Rheumatol Int 27: 608-613.
    • (2006) Rheumatol Int , vol.27 , pp. 608-613
    • Pay, S.1    Erdem, H.2    Pekel, A.3    Simsek, I.4    Musabak, U.5    Sengul, A.6    Dinc, A.7
  • 47
    • 0042071334 scopus 로고    scopus 로고
    • Association of specific interleukin 1 gene cluster polymorphisms with increased susceptibility for Behçet's disease
    • Karasneh J, Hajeer AH, Barrett J, Ollier WE, Thornhill M, Gul A (2003) Association of specific interleukin 1 gene cluster polymorphisms with increased susceptibility for Behçet's disease. Rheumatology (Oxford) 42: 860-864.
    • (2003) Rheumatology (Oxford) , vol.42 , pp. 860-864
    • Karasneh, J.1    Hajeer, A.H.2    Barrett, J.3    Ollier, W.E.4    Thornhill, M.5    Gul, A.6
  • 48
    • 36849059667 scopus 로고    scopus 로고
    • Relationship between periodontal findings and specific polymorphisms of interleukin-1alpha and -1beta in Turkish patients with Behçet's disease
    • Akman A, Ekinci NC, Kacaroglu H, Yavuzer U, Alpsoy E, Yegin O (2008) Relationship between periodontal findings and specific polymorphisms of interleukin-1alpha and -1beta in Turkish patients with Behçet's disease. Arch Dermatol Res 300: 19-26.
    • (2008) Arch Dermatol Res , vol.300 , pp. 19-26
    • Akman, A.1    Ekinci, N.C.2    Kacaroglu, H.3    Yavuzer, U.4    Alpsoy, E.5    Yegin, O.6
  • 49
    • 17844372780 scopus 로고    scopus 로고
    • Behçet's disease as an autoinflammatory disorder
    • Gül A (2005) Behçet's disease as an autoinflammatory disorder. Curr Drug Targets Inflamm Allergy 4: 81-83.
    • (2005) Curr Drug Targets Inflamm Allergy , vol.4 , pp. 81-83
    • Gül, A.1
  • 50
    • 80455173643 scopus 로고    scopus 로고
    • Behçet's disease from the aspect of autoinflammatory disease
    • Ishigatsubo Y, Samukawa S (2011) Behçet's disease from the aspect of autoinflammatory disease. Nihon Rinsho Meneki Gakkai Kaishi 34: 408-419.
    • (2011) Nihon Rinsho Meneki Gakkai Kaishi , vol.34 , pp. 408-419
    • Ishigatsubo, Y.1    Samukawa, S.2
  • 52
    • 84857922054 scopus 로고    scopus 로고
    • Interleukin-1β-regulating antibody XOMA 052 (gevokizumab) in the treatment of acute exacerbations of resistant uveitis of Behçet's disease: an open-label pilot study
    • Gül A, Tugal-Tutkun I, Dinarello CA, Reznikov L, Esen BA, Mirza A, Scannon P, Solinger A (2012) Interleukin-1β-regulating antibody XOMA 052 (gevokizumab) in the treatment of acute exacerbations of resistant uveitis of Behçet's disease: an open-label pilot study. Ann Rheum Dis 71: 563-566.
    • (2012) Ann Rheum Dis , vol.71 , pp. 563-566
    • Gül, A.1    Tugal-Tutkun, I.2    Dinarello, C.A.3    Reznikov, L.4    Esen, B.A.5    Mirza, A.6    Scannon, P.7    Solinger, A.8
  • 54
    • 2442428567 scopus 로고    scopus 로고
    • Serum interleukin-6, procalcitonin and C-reactive protein levels in subjects with active Behçet's disease
    • Adam B, Calikoglu E (2004) Serum interleukin-6, procalcitonin and C-reactive protein levels in subjects with active Behçet's disease. J Eur Acad Dermatol Venereol 18: 318-320.
    • (2004) J Eur Acad Dermatol Venereol , vol.18 , pp. 318-320
    • Adam, B.1    Calikoglu, E.2
  • 57
    • 44149120983 scopus 로고    scopus 로고
    • Tocilizumab may be a potential addition to our weapons against neuro-Behçet's disease
    • Borhani Haghighi A, Safari A (2008) Tocilizumab may be a potential addition to our weapons against neuro-Behçet's disease. Med Hypotheses 71(1): 156-157.
    • (2008) Med Hypotheses , vol.71 , Issue.1 , pp. 156-157
    • Borhani Haghighi, A.1    Safari, A.2
  • 59
    • 84857783564 scopus 로고    scopus 로고
    • Tocilizumab treatment for neuro-Behçet's disease, the first report
    • Shapiro LS, Farrell J, Haghighi AB (2012) Tocilizumab treatment for neuro-Behçet's disease, the first report. Clin Neurol Neurosurg 114: 297-298.
    • (2012) Clin Neurol Neurosurg , vol.114 , pp. 297-298
    • Shapiro, L.S.1    Farrell, J.2    Haghighi, A.B.3
  • 60
    • 84873260003 scopus 로고    scopus 로고
    • Refractory neuro-Behçet treated by tocilizumab: a case report
    • Urbaniak P, Hasler P, Kretzschmar S (2012) Refractory neuro-Behçet treated by tocilizumab: a case report. Clin Exp Rheumatol 30(3 Suppl 72): S73-S75.
    • (2012) Clin Exp Rheumatol , vol.30 , Issue.3 SUPPL. 72
    • Urbaniak, P.1    Hasler, P.2    Kretzschmar, S.3
  • 61
    • 9644262469 scopus 로고    scopus 로고
    • Interferons, interferon-like cytokines, and their receptors
    • Pestka S, Krause CD, Walter MR (2004) Interferons, interferon-like cytokines, and their receptors. Immunol Rev 202: 8-32.
    • (2004) Immunol Rev , vol.202 , pp. 8-32
    • Pestka, S.1    Krause, C.D.2    Walter, M.R.3
  • 62
    • 78751694243 scopus 로고    scopus 로고
    • IFN-alpha blocks IL-17 production by peripheral blood mononuclear cells in Behçet's disease
    • Liu X, Yang P, Wang C, Li F, Kijlstra A (2011) IFN-alpha blocks IL-17 production by peripheral blood mononuclear cells in Behçet's disease. Rheumatology (Oxford) 50: 293-298.
    • (2011) Rheumatology (Oxford) , vol.50 , pp. 293-298
    • Liu, X.1    Yang, P.2    Wang, C.3    Li, F.4    Kijlstra, A.5
  • 63
    • 0036217303 scopus 로고    scopus 로고
    • Interferon alfa-2a in the treatment of Behçet disease: a randomized placebo-controlled and double-blind study
    • Alpsoy E, Durusoy C, Yilmaz E, Ozgurel Y, Ermis O, Yazar S, Basaran E (2002) Interferon alfa-2a in the treatment of Behçet disease: a randomized placebo-controlled and double-blind study. Arch Dermatol 138: 467-471.
    • (2002) Arch Dermatol , vol.138 , pp. 467-471
    • Alpsoy, E.1    Durusoy, C.2    Yilmaz, E.3    Ozgurel, Y.4    Ermis, O.5    Yazar, S.6    Basaran, E.7
  • 66
    • 79952608577 scopus 로고    scopus 로고
    • Long-term efficacy and safety of low-dose and dose-escalating interferon alfa-2a therapy in refractory Behçet uveitis
    • Onal S, Kazokoglu H, Koc A, Akman M, Bavbek T, Direskeneli H, Yavuz S (2011) Long-term efficacy and safety of low-dose and dose-escalating interferon alfa-2a therapy in refractory Behçet uveitis. Arch Ophthalmol 129: 288-294.
    • (2011) Arch Ophthalmol , vol.129 , pp. 288-294
    • Onal, S.1    Kazokoglu, H.2    Koc, A.3    Akman, M.4    Bavbek, T.5    Direskeneli, H.6    Yavuz, S.7
  • 67
    • 50049131639 scopus 로고    scopus 로고
    • BAFF is up-regulated in central nervous system of neuro-Behçet's disease
    • Hamzaoui K, Houman H, Hentati F, Hamzaoui A (2008) BAFF is up-regulated in central nervous system of neuro-Behçet's disease. J Neuroimmunol 200: 111-114.
    • (2008) J Neuroimmunol , vol.200 , pp. 111-114
    • Hamzaoui, K.1    Houman, H.2    Hentati, F.3    Hamzaoui, A.4
  • 69
    • 77953688927 scopus 로고    scopus 로고
    • Release of B cell-activating factor of the TNF family in bronchoalveolar lavage from Behçet's disease with pulmonary involvement
    • Hamzaoui A, Chelbi H, Sassi FH, Hamzaoui K (2010) Release of B cell-activating factor of the TNF family in bronchoalveolar lavage from Behçet's disease with pulmonary involvement. Oxid Med Cell Longev 3: 122-128.
    • (2010) Oxid Med Cell Longev , vol.3 , pp. 122-128
    • Hamzaoui, A.1    Chelbi, H.2    Sassi, F.H.3    Hamzaoui, K.4
  • 70
    • 84862536209 scopus 로고    scopus 로고
    • BAFF/BLyS inhibitors: a new prospect for treatment of systemic lupus erythematosus
    • Fairfax K, Mackay IR, Mackay F (2012) BAFF/BLyS inhibitors: a new prospect for treatment of systemic lupus erythematosus. UBMB Life 64(7): 595-602.
    • (2012) UBMB Life , vol.64 , Issue.7 , pp. 595-602
    • Fairfax, K.1    Mackay, I.R.2    Mackay, F.3
  • 73


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