RUNX1 and NF-E2 upregulation is not specific for MPNs, but is seen in polycythemic disorders with augmented HIF signaling

Blood

Volumn 123, Issue 3, 2014, Pages 391-394

  Kapralova, Katarina ^a,b   Lanikova, Lucie ^a,b   Lorenzo, Felipe ^a   Song, Jihyun ^a   Horvathova, Monika ^b   Divoky, Vladimir ^b   Prchal, Josef T ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b PALACKÝ UNIVERSITY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN; ERYTHROPOIETIN RECEPTOR; HYPOXIA INDUCIBLE FACTOR; TRANSCRIPTION FACTOR NF E2; TRANSCRIPTION FACTOR RUNX1; HIF1A PROTEIN, HUMAN; HIF1A PROTEIN, MOUSE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; NFE2 PROTEIN, HUMAN; NFE2 PROTEIN, MOUSE; RUNX1 PROTEIN, HUMAN; RUNX1 PROTEIN, MOUSE; TRANSCRIPTION FACTOR NF E2 P45 SUBUNIT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; EMBRYO; ERYTHROCYTOSIS; ERYTHROID PRECURSOR CELL; ERYTHROPOIESIS; GAIN OF FUNCTION MUTATION; GENE MUTATION; GENE OVEREXPRESSION; GRANULOCYTE; HETEROZYGOTE; HUMAN; HUMAN CELL; MOUSE; MYELOPROLIFERATIVE NEOPLASM; NONHUMAN; PHENOTYPE; POLYCYTHEMIA VERA; PRIORITY JOURNAL; PROSPECTIVE STUDY; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSGENE; TRANSGENIC MOUSE; UPREGULATION; ANIMAL; CELL HYPOXIA; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MONONUCLEAR CELL; MUTATION; MYELOPROLIFERATIVE DISORDER; POLYCYTHEMIA;

ANIMALS; CELL HYPOXIA; CORE BINDING FACTOR ALPHA 2 SUBUNIT; ERYTHROPOIETIN; GENE EXPRESSION REGULATION; GRANULOCYTES; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LEUKOCYTES, MONONUCLEAR; MICE; MICE, TRANSGENIC; MUTATION; MYELOPROLIFERATIVE DISORDERS; NF-E2 TRANSCRIPTION FACTOR, P45 SUBUNIT; POLYCYTHEMIA; SIGNAL TRANSDUCTION;

EID: 84897019549     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-10-534222     Document Type: Article

References (21)

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