Methylmercury exposure and neurological outcomes in Taiji residents accustomed to consuming whale meat

Environment International

Volumn 68, Issue , 2014, Pages 25-32

  Nakamura, Masaaki ^a   Hachiya, Noriyuki ^a   Murata, Ken ya ^b   Nakanishi, Ichiro ^b   Kondo, Tomoyoshi ^b   Yasutake, Akira ^a   Miyamoto, Ken ichiro ^a   Ser, Ping Han ^c   Omi, Sanae ^c   Furusawa, Hana ^c   Watanabe, Chiho ^c   Usuki, Fusako ^a   Sakamoto, Mineshi ^a  

^a NATIONAL INSTITUTE FOR MINAMATA DISEASE   (Japan)

^b WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

Methylmercury; Neurological outcomes; Selenium; Taiji; Whale meat

Indexed keywords

BLOOD; ELECTROMYOGRAPHY; FISH; FISHERIES; MAGNETIC RESONANCE IMAGING; MEATS; MERCURY (METAL); REGRESSION ANALYSIS; SELENIUM;

CENTRAL NERVOUS SYSTEMS; METHYL MERCURY; MULTIVARIATE REGRESSION ANALYSIS; NEUROLOGICAL EXAMINATION; NEUROLOGICAL OUTCOMES; POSITIVE CORRELATIONS; SUSCEPTIBLE POPULATION; TAIJI;

NEUROLOGY;

METHYLMERCURY; SELENIUM;

ENVIRONMENTAL RISK; HEALTH IMPACT; HEALTH RISK; METHYLMERCURY; MULTIVARIATE ANALYSIS; NUMERICAL MODEL; SELENIUM; TOXICITY; WHALE;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; AUDIOMETRY; BIRTHPLACE; CORRELATION ANALYSIS; DIET; ELECTROMYOGRAPHY; FEMALE; FISH MEAT; FOOD CONTAMINATION; FOOD INTAKE; GEOMETRY; HAIR ANALYSIS; HAIR LEVEL; HUMAN; JAPAN; MAJOR CLINICAL STUDY; MALE; NEUROLOGIC DISEASE; NEUROLOGIC EXAMINATION; NEUROTOXICITY; NUCLEAR MAGNETIC RESONANCE IMAGING; POPULATION EXPOSURE; PRIORITY JOURNAL; SELENIUM BLOOD LEVEL; SEX DIFFERENCE; VERY ELDERLY; WHALE;

CHUBU; HONSHU; JAPAN; NIIGATA;

METHYLMERCURY; NEUROLOGICAL OUTCOMES; SELENIUM; TAIJI; WHALE MEAT;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; DIET; ENVIRONMENTAL POLLUTANTS; FEMALE; FOOD CONTAMINATION; HAIR; HEARING LOSS, SENSORINEURAL; HUMANS; JAPAN; MALE; MEAT; MERCURY POISONING, NERVOUS SYSTEM; METHYLMERCURY COMPOUNDS; MIDDLE AGED; NERVOUS SYSTEM; SELENIUM; SENSATION DISORDERS; WHALES;

EID: 84896989039     PISSN: 01604120     EISSN: 18736750     Source Type: Journal    
DOI: 10.1016/j.envint.2014.03.005     Document Type: Article

References (35)

1. Bakir F., Damluji S.F., Amin-Zaki L., Murtadha M., Khalidi A., al-Rawi N.Y., et al. Methylmercury poisoning in Iraq. Science 1973, 181:230-241.
2. Biedert S., Stuckstedte H. Normal and frequent neurologic findings in elderly patients. Fortschr Neurol Psychiatr 1993, 61:27-32.
3. Clarkson T.W., Magos L., Myers G.J. The toxicology of mercury-current exposures and clinical manifestations. N Engl JMed 2003, 349:1731-1737.
4. Crofton K.M., Kodavanti P.R., Derr-Yellin E.C., Casey A.C., Kehn L.S. PCBs, thyroid hormones, and ototoxicity in rats: crossfostering experiments demonstrate the impact of postnatal lactation exposure. Toxicol Sci 2000, 57:131-140.
5. Endo T., Haraguchi K. High mercury levels in hair samples from residents of Taiji, a Japanese whaling town. Mar Pollut Bull 2010, 60:743-747.
6. Endo T., Hotta Y., Haraguchi K., Sakata M. Mercury contamination in the red meat of whales and dolphins marketed for human consumption in Japan. Environ Sci Technol 2003, 37:2681-2685.
7. Eto K. Minamata disease. Neuropathology 2000, (Suppl. 20):S14-S19.
8. Eto K., Oyanagi S., Itai Y., Tokunaga H., Takizawa Y., Suda I. A fetal type of Minamata disease: an autopsy case report with special reference to the nervous system. Mol Chem Neuropathol 1992, 16:171-186.
9. Heath J.C., Banna K.M., Reed M.N., Pesek E.F., Cole N., Li J., et al. Dietary selenium protects against selected signs of aging and methylmercury exposure. Neurotoxicology 2010, 31:169-179.
10. Kodama T., Nakagawa M., Arimura K., Koriyama C., Akiba S., Osame M. Cross-sectional analysis of neurological findings among healthy elderly: study in a remote island in Kagoshima, Japan. Neuroepidemiology 2002, 21:36-43.
11. Korogi Y., Takahashi M., Okajima T., Eto K. MR findings of Minamata disease-organic mercury poisoning. J Magn Reson Imaging 1998, 8:308-316.
12. Kosatsky T., Foran P. Do historic studies of fish consumers support the widely accepted LOEL for methylmercury in adults. Neurotoxicology 1996, 17:177-186.
13. Lailson-Brito J., Cruz R., Dorneles P.R., Andrade L., Azevedo A.F., Fragoso A.B.., et al. Mercury-selenium relationships in liver of Guiana dolphin: the possible role of Kupffer cells in the detoxification process by tiemannite formation. PLoS One 2012, 7:e42162.
14. Lebel J., Mergler D., Lucotte M., Amorim M., Dolbec J., Miranda D., et al. Evidence of early nervous system dysfunction in Amazonian populations exposed to low-levels of methylmercury. Neurotoxicology 1996, 17(Spring (1)):157-167.
15. Lebel J., Mergler D., Branches F., Lucotte M., Amorim M., Larribe F., et al. Neurotoxic effects of low-level methylmercury contamination in the Amazonian Basin. Environ Res 1998, 79:20-32.
16. Likosky W.H., Hinman A.R., Barthel W.F. Organic mercury poisoning, New Mexico. Neurology 1970, 20:401.
17. Murase N., Rothwell J.C., Kaji R., Urushihara R., Nakamura K., Murayama N., et al. Subthreshold low-frequency repetitive transcranial magnetic stimulation over the premotor cortex modulates writer's cramp. Brain 2005, 128:104-115.
18. Myers G.J., Davidson P.W., Strain J.J. Nutrient and methyl mercury exposure from consuming fish. J Nutr 2007, 137:2805-2808.
19. Ohkawa T., Uenoyama H., Tanida K., Ohmae T. Ultra trace mercury analysis by dry thermal decomposition in alumina porcelain tube. J Hyg Chem 1977, 23:13-22.
20. Parajuli R.P., Fujiwara T., Umezaki M., Furusawa H., Ser P.H., Watanabe C. Cord blood levels of toxic and essential trace elements and their determinants in the Terai region of Nepal: a birth cohort study. Biol Trace Elem Res 2012, 147:75-83.
21. Ralston N.V., Raymond L.J. Dietary selenium's protective effects against methylmercury toxicity. Toxicology 2010, 278:112-123.
22. Ralston N.V., Blackwell J.L., Raymond L.J. Importance of molar ratios in selenium-dependent protection against methylmercury toxicity. Biol Trace Elem Res 2007, 119:255-268.
23. Sakamoto M., Yasutake A., Kakita A., Ryufuku M., Chan H.M., Yamamoto M., et al. Selenomethionine protects against neuronal degeneration by methylmercury in the developing rat cerebrum. Environ Sci Technol 2013, 47:2862-2868.
24. Sugiura Y., Tamai Y., Tanaka H. Selenium protection against mercury toxicity: high binding affinity of methylmercury by selenium-containing ligands in comparison with sulfur-containing ligands. Bioinorg Chem 1978, 9:167-180.
25. Tokuomi H., Okajima T., Kanai J., Tsunoda M., Ichiyasu Y., Misumi H., et al. Minamata disease. World Neurol 1961, 2:536-545.
26. Tokuomi H., Okajima T., Kanai J., Tsunoda M., Ichiyasu Y., Misumi H., et al. Minamata disease - an unusual neurological disorder occurring in Minamata, Japan. Kumamoto Med J 1961, 14:47-64.
27. Uchino M., Okajima T., Eto K., Kumamoto T., Mishima I., Ando M. Neurologic features of chronic Minamata disease (organic mercury poisoning) certified at autopsy. Intern Med 1995, 34:744-747.
28. Uchino M., Mita S., Satoh H., Hirano T., Arimura K., Nakagawa M., et al. Clinical investigation of the lesions responsible for sensory disturbance in Minamata disease. Tohoku J Exp Med 2001, 195:181-189.
29. Usuki F., Yamashita A., Fujimura M. Post-transcriptional defects of antioxidant selenoenzymes cause oxidative stress under methylmercury exposure. J Biol Chem 2011, 286:6641-6649.
30. Weihe P., Joensen H.D. Dietary recommendations regarding pilot whale meat and blubber in the Faroe Islands. Int J Circumpolar Health 2012, 71:18594.
31. WHO Methylmercury. Environmental health criteria 1990, 101. World Health Organization, Geneva.
32. WHO Methylmercury. Evaluation of certain food additives and contaminants. Sixty-first report of the Joint FAO/WHO Expert Committee on Food Additives 2004, World Health Organization, Geneva.
33. Yasutake A., Matsumoto M., Yamaguchi M., Hachiya N. Current hair mercury levels in Japanese: survey in five districts. Current hair mercury levels in Japanese: survey in five districts. Tohoku J Exp Med 2003, 199:161-169.
34. Yasutake A., Matsumoto M., Yamaguchi M., Hachiya N. Current hair mercury levels in Japanese for estimation of methylmercury exposure. J Health Sci 2004, 50:120-125.
35. Yorifuji T., Tsuda T., Takao S., Suzuki E., Harada M. Total mercury content in hair and neurologic signs: historic data from Minamata. Epidemiology 2009, 20:188-193.