Locating the binding sites of antitumor drug tamoxifen and its metabolites with DNA

Journal of Pharmaceutical and Biomedical Analysis

Volumn 95, Issue , 2014, Pages 193-199

  Bourassa, P ^a   Thomas, T J ^b   Tajmir Riahi, H A ^a  

^a UNIVERSITÉ DU QUÉBEC À TROIS RIVIÈRES   (Canada)

^b ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

Binding site; Conformation; DNA; Endoxifen; Tamoxifen

Indexed keywords

AFIMOXIFENE; DNA; ENDOXIFEN; TAMOXIFEN; ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; DNA ADDUCT; DNA CONFORMATION; DNA DRUG COMPLEX; DRUG BINDING; DRUG BINDING SITE; DRUG DNA BINDING; DRUG DNA INTERACTION; HYDROPHILICITY; HYDROPHOBICITY; INFRARED SPECTROSCOPY; METABOLITE; MOLECULAR MODEL; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; STRUCTURE ANALYSIS; ULTRAVIOLET SPECTROSCOPY; BINDING SITE; CHEMISTRY; CIRCULAR DICHROISM; CONFORMATION; METABOLISM; MOLECULAR DOCKING; SPECTROFLUOROMETRY;

ANTINEOPLASTIC AGENTS, HORMONAL; BINDING SITES; CIRCULAR DICHROISM; DNA; MOLECULAR DOCKING SIMULATION; NUCLEIC ACID CONFORMATION; SPECTROMETRY, FLUORESCENCE; TAMOXIFEN;

EID: 84896974301     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2014.02.028     Document Type: Article

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