Cys34-cysteinylated human serum albumin is a sensitive plasma marker in oxidative stress-related chronic diseases

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Nagumo, Kohei ^a   Tanaka, Motohiko ^b   Chuang, Victor Tuan Giam ^c   Setoyama, Hiroko ^b   Watanabe, Hiroshi ^a   Yamada, Naoyuki ^d   Kubota, Kazuyuki ^d   Tanaka, Motoko ^e   Matsushita, Kazutaka ^e   Yoshida, Akira ^f   Jinnouchi, Hideaki ^f   Anraku, Makoto ^g   Kadowaki, Daisuke ^a   Ishima, Yu ^a   Sasaki, Yutaka ^b   Otagiri, Masaki ^g   Maruyama, Toru ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

^c CURTIN UNIVERSITY   (Australia)

^d AJINOMOTO CO INC   (Japan)

^e Department of Nephrology Akebono Clinic   (Japan)

^f Jinnouchi Clinic   (Japan)

^g SOJO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED OXIDATION PROTEIN PRODUCT; BILIRUBIN; BIOLOGICAL MARKER; BRANCHED CHAIN AMINO ACID; CYSTEINE; DIAZEPAM; HUMAN SERUM ALBUMIN; PLASMA MARKER; TRYPTOPHAN; UNCLASSIFIED DRUG; WARFARIN;

ADULT; AGED; AMINO ACID SUPPLEMENTATION; ANALYTIC METHOD; ARTICLE; BINDING AFFINITY; BLOOD SAMPLING; CELL LEVEL; CHRONIC DISEASE; CHRONIC KIDNEY DISEASE; CHRONIC LIVER DISEASE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYSTEINYLATION; DIABETES MELLITUS; DISEASE COURSE; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; LABORATORY DIAGNOSIS; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; MOLECULAR MECHANICS; OXIDATION; OXIDATIVE STRESS; PROTEIN BINDING; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PURIFICATION; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS; SUPPLEMENTATION; TIME OF FLIGHT MASS SPECTROMETRY; TREATMENT RESPONSE;

AGED; AMINO ACIDS, BRANCHED-CHAIN; BILIRUBIN; BIOLOGICAL MARKERS; CHRONIC DISEASE; CYSTEINE; DIABETES MELLITUS; DIAZEPAM; FEMALE; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMANS; LIVER CIRRHOSIS; MALE; MIDDLE AGED; MODELS, MOLECULAR; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEIN BINDING; RENAL INSUFFICIENCY; SERUM ALBUMIN; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TRYPTOPHAN; WARFARIN;

EID: 84896970499     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0085216     Document Type: Article

References (40)

1. Association AD (2013) Diagnosis and classification of diabetes mellitus. Diabetes Care 36 Suppl 1: S67-74.
2. Furusyo N, Hayashi J (2013) Glycated albumin and diabetes mellitus. Biochim Biophys Acta.
3. Poli G (2000) Pathogenesis of liver fibrosis: role of oxidative stress. Mol Aspects Med 21: 49-98.
4. Descamps-Latscha B, Witko-Sarsat V (2001) Importance of oxidatively modified proteins in chronic renal failure. Kidney Int Suppl 78: S108-113. (Pubitemid 32144081)
5. Pergola PE, Raskin P, Toto RD, Meyer CJ, Huff JW, et al. (2011) Bardoxolone methyl and kidney function in CKD with type 2 diabetes. N Engl J Med 365: 327-336.
6. Sogami M, Era S, Nagaoka S, Kuwata K, Kida K, et al. (1985) High-performance liquid chromatographic studies on non-mercapt in equilibrium with mercapt conversion of human serum albumin. II. J Chromatogr 332: 19-27.
7. Terawaki H, Yoshimura K, Hasegawa T, Matsuyama Y, Negawa T, et al. (2004) Oxidative stress is enhanced in correlation with renal dysfunction: examination with the redox state of albumin. Kidney Int 66: 1988-1993.
8. Anraku M, Kitamura K, Shinohara A, Adachi M, Suenga A, et al. (2004) Intravenous iron administration induces oxidation of serum albumin in hemodialysis patients. Kidney Int 66: 841-848. (Pubitemid 38982029)
9. Anraku M, Kitamura K, Shintomo R, Takeuchi K, Ikeda H, et al. (2008) Effect of intravenous iron administration frequency on AOPP and inflammatory biomarkers in chronic hemodialysis patients: a pilot study. Clin Biochem 41: 1168-1174.
10. Shimoishi K, Anraku M, Kitamura K, Tasaki Y, Taguchi K, et al. (2007) An oral adsorbent, AST-120 protects against the progression of oxidative stress by reducing the accumulation of indoxyl sulfate in the systemic circulation in renal failure. Pharm Res 24: 1283-1289. (Pubitemid 46870593)
11. Kadowaki D, Anraku M, Tasaki Y, Kitamura K, Wakamatsu S, et al. (2007) Effect of olmesartan on oxidative stress in hemodialysis patients. Hypertens Res 30: 395-402. (Pubitemid 46958889)
12. Yamasaki K, Chuang VT, Maruyama T, Otagiri M (2013) Albumin-drug interaction and its clinical implication. Biochim Biophys Acta.
13. Sengupta S, Chen H, Togawa T, DiBello PM, Majors AK, et al. (2001) Albumin thiolate anion is an intermediate in the formation of albumin-S-S-homocysteine. J Biol Chem 276: 30111-30117.
14. Alvarez B, Carballal S, Turell L, Radi R (2010) Formation and reactions of sulfenic acid in human serum albumin. Methods Enzymol 473: 117-136.
15. Oettl K, Stauber RE (2007) Physiological and pathological changes in the redox state of human serum albumin critically influence its binding properties. Br J Pharmacol 151: 580-590. (Pubitemid 47016287)
16. Narazaki R, Otagiri M (1997) Covalent binding of a bucillamine derivative with albumin in sera from healthy subjects and patients with various diseases. Pharm Res 14: 351-353. (Pubitemid 27160948)
17. Kawakami A, Kubota K, Yamada N, Tagami U, Takehana K, et al. (2006) Identification and characterization of oxidized human serum albumin. A slight structural change impairs its ligand-binding and antioxidant functions. FEBS J 273: 3346-3357. (Pubitemid 43990937)
18. Kubota K, Nakayama A, Takehana K, Kawakami A, Yamada N, et al. (2009) A simple stabilization method of reduced albumin in blood and plasma for the reduced/oxidized albumin ratio measurement. Int J Biomed Sci 5: 293-301.
19. Regazzoni L, Del Vecchio L, Altomare A, Yeum KJ, Cusi D, et al. (2013) Human serum albumin cysteinylation is increased in end stage renal disease patients and reduced by hemodialysis: mass spectrometry studies. Free Radic Res 47: 172-180.
20. Boisvert MR, Koski KG, Skinner CD (2010) Increased oxidative modifications of amniotic fluid albumin in pregnancies associated with gestational diabetes mellitus. Anal Chem 82: 1133-1137.
21. Mera K, Anraku M, Kitamura K, Nakajou K, Maruyama T, et al. (2005) The structure and function of oxidized albumin in hemodialysis patients: Its role in elevated oxidative stress via neutrophil burst. Biochem Biophys Res Commun 334: 1322-1328. (Pubitemid 41074719)
22. Jagannathan V, March C, Venitz J (1995) Determination of unbound L-tryptophan in human plasma using high-performance liquid chromatography with fluorescence detection. Biomed Chromatogr 9: 305-308. (Pubitemid 3002761)
23. Mera K, Takeo K, Izumi M, Maruyama T, Nagai R, et al. (2010) Effect of reactive-aldehydes on the modification and dysfunction of human serum albumin. J Pharm Sci 99: 1614-1625.
24. Watanabe H, Tanase S, Nakajou K, Maruyama T, Kragh-Hansen U, et al. (2000) Role of arg-410 and tyr-411 in human serum albumin for ligand binding and esterase-like activity. Biochem J 349 Pt 3: 813-819. (Pubitemid 30609413)
25. Minomo A, Ishima Y, Kragh-Hansen U, Chuang VT, Uchida M, et al. (2011) Biological characteristics of two lysines on human serum albumin in the high-affinity binding of 4Z,15Z-bilirubin-IXa revealed by phage display. FEBS J 278: 4100-4111.
26. Witko-Sarsat V, Friedlander M, Capeillère-Blandin C, Nguyen-Khoa T, Nguyen AT, et al. (1996) Advanced oxidation protein products as a novel marker of oxidative stress in uremia. Kidney Int 49: 1304-1313. (Pubitemid 26166404)
27. Borges CR, Oran PE, Buddi S, Jarvis JW, Schaab MR, et al. (2011) Building multidimensional biomarker views of type 2 diabetes on the basis of protein microheterogeneity. Clin Chem 57: 719-728.
28. Musante L, Candiano G, Petretto A, Bruschi M, Dimasi N, et al. (2007) Active focal segmental glomerulosclerosis is associated with massive oxidation of plasma albumin. J Am Soc Nephrol 18: 799-810. (Pubitemid 46434497)
29. Carballal S, Radi R, Kirk MC, Barnes S, Freeman BA, et al. (2003) Sulfenic acid formation in human serum albumin by hydrogen peroxide and peroxynitrite. Biochemistry 42: 9906-9914. (Pubitemid 37012866)
30. Anraku M, Chuang VT, Maruyama T, Otagiri M (2013) Redox properties of serum albumin. Biochim Biophys Acta.
31. Jalan R, Schnurr K, Mookerjee RP, Sen S, Cheshire L, et al. (2009) Alterations in the functional capacity of albumin in patients with decompensated cirrhosis is associated with increased mortality. Hepatology 50: 555-564.
32. Oettl K, Birner-Gruenberger R, Spindelboeck W, Stueger HP, Dorn L, et al. (2013) Oxidative Albumin Damage in Chronic Liver Failure: Relation to Albumin Binding Capacity, Liver Dysfunction and Survival. J Hepatol.
33. Takikawa H, Sugiyama Y, Hanano M, Kurita M, Yoshida H, et al. (1987) A novel binding site for bile acids on human serum albumin. Biochim Biophys Acta 926: 145-153. (Pubitemid 17155458)
34. Kawaguchi T, Izumi N, Charlton MR, Sata M (2011) Branched-chain amino acids as pharmacological nutrients in chronic liver disease. Hepatology 54: 1063-1070.
35. Nishitani S, Ijichi C, Takehana K, Fujitani S, Sonaka I (2004) Pharmacological activities of branched-chain amino acids: specificity of tissue and signal transduction. Biochem Biophys Res Commun 313: 387-389. (Pubitemid 37543597)
36. Kuwahata M, Yoshimura T, Sawai Y, Amano S, Tomoe Y, et al. (2008) Localization of polypyrimidine-tract-binding protein is involved in the regulation of albumin synthesis by branched-chain amino acids in HepG2 cells. J Nutr Biochem 19: 438-447. (Pubitemid 351783404)
37. Ichikawa K, Okabayashi T, Shima Y, Iiyama T, Takezaki Y, et al. (2012) Branched-chain amino acid-enriched nutrients stimulate antioxidant DNA repair in a rat model of liver injury induced by carbon tetrachloride. Mol Biol Rep 39: 10803-10810.
38. Terawaki H, Matsuyama Y, Matsuo N, Ogura M, Mitome J, et al. (2012) A lower level of reduced albumin induces serious cardiovascular incidence among peritoneal dialysis patients. Clin Exp Nephrol 16: 629-635.
39. Iwao Y, Ishima Y, Yamada J, Noguchi T, Kragh-Hansen U, et al. (2012) Quantitative evaluation of the role of cysteine and methionine residues in the antioxidant activity of human serum albumin using recombinant mutants. IUBMB Life 64: 450-454.
40. Anraku M, Takeuchi K, Watanabe H, Kadowaki D, Kitamura K, et al. (2011) Quantitative analysis of cysteine-34 on the anitioxidative properties of human serum albumin in hemodialysis patients. J Pharm Sci 100: 3968-3976.