Identification and characterization of oxidized human serum albumin: A slight structural change impairs its ligand-binding and antioxidant functions

FEBS Journal

Volumn 273, Issue 14, 2006, Pages 3346-3357

  Kawakami, Asami ^a   Kubota, Kazuyuki ^a   Yamada, Naoyuki ^a   Tagami, Uno ^a   Takehana, Kenji ^a   Sonaka, Ichiro ^a   Suzuki, Eiichiro ^a   Hirayama, Kazuo ^a  

^a AJINOMOTO CO INC   (Japan)

Author keywords

ESI TOFMS; Human serum albumin; Mercaptoalbumin; Nonmercaptoalbumin; Oxidation

Indexed keywords

ANTIOXIDANT; CEFAZOLIN; SERUM ALBUMIN; VERAPAMIL;

ANTIOXIDANT ACTIVITY; ARTICLE; BINDING AFFINITY; BLOOD SAMPLING; DISULFIDE BOND; ENZYME MODIFICATION; HUMAN; HUMAN CELL; LIGAND BINDING; OXIDATION REDUCTION REACTION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANTIOXIDANTS; CHROMATOGRAPHY, LIQUID; COMPUTER SIMULATION; CYSTEINE; ELECTRON SPIN RESONANCE SPECTROSCOPY; HUMANS; HYDROLYSIS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; OXIDATION-REDUCTION; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN CONFORMATION; SERUM ALBUMIN; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPSIN;

EID: 33745635418     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2006.05341.x     Document Type: Article

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