-
1
-
-
77951702343
-
Genetic heterogeneity in human disease
-
doi:10.1016/j.cell.2010.03.032
-
McClellan J, King MC. 2010 Genetic heterogeneity in human disease. Cell 141, 210-217. (doi:10.1016/j.cell.2010.03.032)
-
(2010)
Cell
, vol.141
, pp. 210-217
-
-
McClellan, J.1
King, M.C.2
-
2
-
-
84860910413
-
The predictive capacity of personal genome sequencing
-
doi:10.1126/scitranslmed.3003380
-
Roberts NJ, Vogelstein JT, Parmigiani G, Kinzler KW, Vogelstein B, Velculescu VE. 2012 The predictive capacity of personal genome sequencing. Sci. Transl. Med. 4, 133ra58. (doi:10.1126/scitranslmed.3003380)
-
(2012)
Sci. Transl. Med.
, vol.4
-
-
Roberts, N.J.1
Vogelstein, J.T.2
Parmigiani, G.3
Kinzler, K.W.4
Vogelstein, B.5
Velculescu, V.E.6
-
3
-
-
0034602686
-
The middle way
-
doi:10.1073/pnas.97.1.32
-
Laughlin RB, Pines D, Schmalian J, Stojkovic BP, Wolynes P. 2000 The middle way. Proc. Natl Acad. Sci. USA 97, 32-37. (doi:10.1073/pnas.97.1.32)
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 32-37
-
-
Laughlin, R.B.1
Pines, D.2
Schmalian, J.3
Stojkovic, B.P.4
Wolynes, P.5
-
4
-
-
0004146634
-
-
Cambridge, UK: Cambridge University Press
-
Schrödinger E. 1944 What is life? Cambridge, UK: Cambridge University Press.
-
(1944)
What Is Life?
-
-
Schrödinger, E.1
-
5
-
-
57849156886
-
The riddle of 'life,' a biologist's critical view
-
doi:10.1007/s00114-008-0422-8
-
Penzlin H. 2009 The riddle of 'life,' a biologist's critical view. Naturwissenschaften 96, 1-23. (doi:10.1007/s00114-008-0422-8)
-
(2009)
Naturwissenschaften
, vol.96
, pp. 1-23
-
-
Penzlin, H.1
-
7
-
-
80051622587
-
A comparison of two cell regulatory models entailing high dimensional attractors representing phenotype
-
doi:10.1016/j.pbiomolbio.2011.01.002
-
Baverstock K. 2011 A comparison of two cell regulatory models entailing high dimensional attractors representing phenotype. Prog. Biophys. Mol. Biol. 106, 443-449. (doi:10.1016/j.pbiomolbio.2011.01.002)
-
(2011)
Prog. Biophys. Mol. Biol.
, vol.106
, pp. 443-449
-
-
Baverstock, K.1
-
8
-
-
84880699689
-
Physiology is rocking the foundations of evolutionary biology
-
Noble D. 2013 Physiology is rocking the foundations of evolutionary biology. Exp. Physiol. 98, 1235-1243.
-
(2013)
Exp. Physiol.
, vol.98
, pp. 1235-1243
-
-
Noble, D.1
-
9
-
-
79952677354
-
The cell in an era of systems biology
-
doi:10.1016/j.cell.2011.02.045
-
Nurse P, Hayles J. 2011 The cell in an era of systems biology. Cell 144, 850-854. (doi:10.1016/j.cell.2011.02.045)
-
(2011)
Cell
, vol.144
, pp. 850-854
-
-
Nurse, P.1
Hayles, J.2
-
10
-
-
34247953814
-
More is different
-
doi:10.1126/science.177.4047.393
-
Anderson PW. 1972 More is different. Science 177, 393-396. (doi:10.1126/science.177.4047.393)
-
(1972)
Science
, vol.177
, pp. 393-396
-
-
Anderson, P.W.1
-
11
-
-
80052963301
-
All in action
-
doi:10.3390/e12112333
-
Annila A. 2010 All in action. Entropy 12, 2333-2358. (doi:10.3390/ e12112333)
-
(2010)
Entropy
, vol.12
, pp. 2333-2358
-
-
Annila, A.1
-
12
-
-
33847219928
-
Natural process: Natural selection
-
doi:10.1016/j.bpc.2007.01.005
-
Sharma V, Annila A. 2007 Natural process: natural selection. Biophys. Chem. 127, 123-128. (doi:10.1016/j.bpc.2007.01.005)
-
(2007)
Biophys. Chem.
, vol.127
, pp. 123-128
-
-
Sharma, V.1
Annila, A.2
-
13
-
-
78649676398
-
Natural patterns of energy dispersal
-
doi:10.1016/j.plrev.2010.10.001
-
Makela T, Annila A. 2010 Natural patterns of energy dispersal. Phys. Life Rev. 7, 477-498. (doi:10.1016/j.plrev.2010.10.001)
-
(2010)
Phys. Life Rev.
, vol.7
, pp. 477-498
-
-
Makela, T.1
Annila, A.2
-
14
-
-
84861193044
-
Natural emergence
-
doi:10.1002/cplx.21388
-
Pernu TK, Annila A. 2012 Natural emergence. Complexity 17, 44-47. (doi:10.1002/cplx.21388)
-
(2012)
Complexity
, vol.17
, pp. 44-47
-
-
Pernu, T.K.1
Annila, A.2
-
15
-
-
84863951596
-
The RNA worlds in context
-
doi:10.1101/cshperspect.a006742
-
Cech TR. 2012 The RNA worlds in context. Cold Spring Harb. Perspect. Biol. 4, a006742. (doi:10.1101/cshperspect.a006742)
-
(2012)
Cold Spring Harb. Perspect. Biol.
, vol.4
-
-
Cech, T.R.1
-
16
-
-
84894432265
-
Towards an evolutionary theory of the origin of life based on kinetics and thermodynamics
-
doi:10.1098/rsob.130156
-
Pascal R, Pross A, Sutherland JD. 2013 Towards an evolutionary theory of the origin of life based on kinetics and thermodynamics. Open Biol. 3, 130156. (doi:10.1098/rsob.130156)
-
(2013)
Open Biol.
, vol.3
, pp. 130156
-
-
Pascal, R.1
Pross, A.2
Sutherland, J.D.3
-
17
-
-
84901486462
-
The significance of sex
-
doi:10.1016/j.biosystems.2012.09.006
-
Annila A, Annila E. 2012 The significance of sex. Biosystems 110, 156-161. (doi:10.1016/j.biosystems.2012.09.006)
-
(2012)
Biosystems
, vol.110
, pp. 156-161
-
-
Annila, A.1
Annila, E.2
-
18
-
-
0004190112
-
-
revised edition. New York, NY: Cambridge University Press
-
Dyson FJ. 1999 Origins of life, revised edition. New York, NY: Cambridge University Press.
-
(1999)
Origins of Life
-
-
Dyson, F.J.1
-
19
-
-
57649114778
-
Why did life emerge?
-
doi:10.1017/S1473550408004308
-
Annila A, Annila E. 2008 Why did life emerge? Int. J. Astrobiol. 7, 293-300. (doi:10.1017/S1473550408004308)
-
(2008)
Int. J. Astrobiol.
, vol.7
, pp. 293-300
-
-
Annila, A.1
Annila, E.2
-
20
-
-
48449102277
-
Epigenetic regulation of the mammalian cell
-
doi:10.1371/journal.pone.0002290
-
Baverstock K, Rönkkö M. 2008 Epigenetic regulation of the mammalian cell. PLoS ONE 3, e2290. (doi:10.1371/journal.pone.0002290)
-
(2008)
PLoS ONE
, vol.3
-
-
Baverstock, K.1
Rönkkö, M.2
-
21
-
-
84878122993
-
The role of information in cell regulation
-
doi:10.1016/j.pbiomolbio.2012.09.007
-
Baverstock K. 2013 The role of information in cell regulation. Prog. Biophys. Mol. Biol. 111, 141-143. (doi:10.1016/j.pbiomolbio.2012.09.007)
-
(2013)
Prog. Biophys. Mol. Biol.
, vol.111
, pp. 141-143
-
-
Baverstock, K.1
-
22
-
-
58149356954
-
Protein folding as an evolutionary process
-
doi:10.1016/j.physa.2008.12.004
-
Sharma V, Kaile VRI, Annila A. 2009 Protein folding as an evolutionary process. Physica A 388, 851-862. (doi:10.1016/j.physa.2008.12.004)
-
(2009)
Physica A
, vol.388
, pp. 851-862
-
-
Sharma, V.1
Kaile, V.R.I.2
Annila, A.3
-
23
-
-
84878143968
-
Life as physics and chemistry: A system view of biology
-
doi:10.1016/j.pbiomolbio.2012.09.002
-
Baverstock K. 2013 Life as physics and chemistry: a system view of biology. Prog. Biophys. Mol. Biol. 111, 108-115. (doi:10.1016/j.pbiomolbio.2012. 09.002)
-
(2013)
Prog. Biophys. Mol. Biol.
, vol.111
, pp. 108-115
-
-
Baverstock, K.1
-
25
-
-
0003453618
-
-
New York, NY: Oxford University Press
-
Gâanti T. 2003 The principles of life. New York, NY: Oxford University Press.
-
(2003)
The Principles of Life
-
-
Gâanti, T.1
-
28
-
-
21344466628
-
An attempt to classify the 'varieties' of animals, with observations on the marked seasonal and other changes which naturally take place in various British species, and which do not constitute varieties
-
Blyth E. 1835 An attempt to classify the 'varieties' of animals, with observations on the marked seasonal and other changes which naturally take place in various British species, and which do not constitute varieties. Mag. Nat. Hist. 8, 40-53.
-
(1835)
Mag. Nat. Hist.
, vol.8
, pp. 40-53
-
-
Blyth, E.1
-
29
-
-
0016103841
-
Charles Darwin's debt to Malthus and Edward Blyth
-
doi:10.1007/BF00351207
-
Schwartz JS. 1974 Charles Darwin's debt to Malthus and Edward Blyth. J. Hist. Biol. 7, 301-318. (doi:10.1007/BF00351207)
-
(1974)
J. Hist. Biol.
, vol.7
, pp. 301-318
-
-
Schwartz, J.S.1
-
32
-
-
0015859467
-
Principles that govern the folding of protein chains
-
doi:10.1126/science.181.4096.223
-
Anfinsen CB. 1973 Principles that govern the folding of protein chains. Science 181, 223-230. (doi:10.1126/science.181.4096.223)
-
(1973)
Science
, vol.181
, pp. 223-230
-
-
Anfinsen, C.B.1
-
33
-
-
84865695733
-
Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition
-
doi:10.1016/j.cell.2012.06.047
-
Taipale M, Krykbaeva I, Koeva M, Kayatekin C, Westover KD, Karras GI, Lindquist S. 2012 Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. Cell 150, 987-1001. (doi:10.1016/j.cell. 2012.06.047)
-
(2012)
Cell
, vol.150
, pp. 987-1001
-
-
Taipale, M.1
Krykbaeva, I.2
Koeva, M.3
Kayatekin, C.4
Westover, K.D.5
Karras, G.I.6
Lindquist, S.7
-
34
-
-
79959812980
-
Comparative analysis of proteome and transcriptome variation in mouse
-
doi:10.1371/journal.pgen.1001393
-
Ghazalpour A et al. 2011 Comparative analysis of proteome and transcriptome variation in mouse. PLoS Genet. 7, e1001393. (doi:10.1371/journal. pgen.1001393)
-
(2011)
PLoS Genet.
, vol.7
-
-
Ghazalpour, A.1
-
36
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
doi:10.1038/nature08494
-
Manolio TA et al. 2009 Finding the missing heritability of complex diseases. Nature 461, 747-753. (doi:10.1038/nature08494)
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
-
37
-
-
84860909299
-
A theory of biological relativity: No privileged level of causation
-
doi:10.1098/rsfs.2011.0067
-
Noble D. 2012 A theory of biological relativity: no privileged level of causation. Interface Focus 2, 55-64. (doi:10.1098/rsfs.2011.0067)
-
(2012)
Interface Focus
, vol.2
, pp. 55-64
-
-
Noble, D.1
-
38
-
-
84878120232
-
A biological relativity view of the relationships between genomes and phenotypes
-
doi:10.1016/j.pbiomolbio.2012.09.004
-
Noble D. 2013 A biological relativity view of the relationships between genomes and phenotypes. Prog. Biophys. Mol. Biol. 111, 59-65. (doi:10.1016/j.pbiomolbio.2012.09.004)
-
(2013)
Prog. Biophys. Mol. Biol.
, vol.111
, pp. 59-65
-
-
Noble, D.1
-
40
-
-
0003707485
-
-
1st edn. New York, NY: Pantheon Books
-
Lewontin RC, Rose SPR, Kamin LJ. 1984 Not in our genes: biology, ideology, and human nature, 1st edn. New York, NY: Pantheon Books.
-
(1984)
Not in Our Genes: Biology, Ideology, and Human Nature
-
-
Lewontin, R.C.1
Rose, S.P.R.2
Kamin, L.J.3
-
41
-
-
0001488189
-
A kernal of truth? On the reality of the genetic programme
-
Moss L. 1992 A kernal of truth? On the reality of the genetic programme. PSA: Proc. Biennial Meet. 1, 335-348.
-
(1992)
PSA: Proc. Biennial Meet.
, vol.1
, pp. 335-348
-
-
Moss, L.1
-
44
-
-
2942526841
-
A new biology for a new century
-
doi:10.1128/MMBR.68.2.173-186.2004
-
Woese CR. 2004 A new biology for a new century. Microbiol. Mol. Biol. Rev. 68, 173-186. (doi:10.1128/MMBR.68.2.173-186.2004)
-
(2004)
Microbiol. Mol. Biol. Rev.
, vol.68
, pp. 173-186
-
-
Woese, C.R.1
-
45
-
-
84878146636
-
Rethinking the (im)possible in evolution
-
doi:10.1016/j.pbiomolbio.2012.08.016
-
Shapiro JA. 2013 Rethinking the (im)possible in evolution. Prog. Biophys. Mol. Biol. 111, 92-96. (doi:10.1016/j.pbiomolbio.2012.08.016)
-
(2013)
Prog. Biophys. Mol. Biol.
, vol.111
, pp. 92-96
-
-
Shapiro, J.A.1
-
46
-
-
0036845254
-
Conrad Hal Waddington: The last renaissance biologist?
-
doi:10.1038/nrg933
-
Slack JM. 2002 Conrad Hal Waddington: the last renaissance biologist? Nat. Rev. Genet. 3, 889-895. (doi:10.1038/nrg933)
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 889-895
-
-
Slack, J.M.1
-
47
-
-
73049167504
-
Teleonomic mechanisms in cellular metabolism, growth, and differentiation
-
doi:10.1101/SQB.1961.026.01.048
-
Monod J, Jacob F. 1961 Teleonomic mechanisms in cellular metabolism, growth, and differentiation. Cold Spring Harb. Symp. Quant. Biol. 26, 389-401. (doi:10.1101/SQB.1961.026.01.048)
-
(1961)
Cold Spring Harb. Symp. Quant. Biol.
, vol.26
, pp. 389-401
-
-
Monod, J.1
Jacob, F.2
-
49
-
-
33947204103
-
An artificial ecosystem: Emergent dynamics and lifelike properties
-
doi:10.1162/artl.2007.13.2.159
-
Rönkkö M. 2007 An artificial ecosystem: emergent dynamics and lifelike properties. Artif. Life 13, 159-187. (doi:10.1162/artl.2007.13.2.159)
-
(2007)
Artif. Life
, vol.13
, pp. 159-187
-
-
Rönkkö, M.1
-
50
-
-
0000861206
-
Order from disorder: The thermodynamics of complexity in biology
-
(eds MP Murphy, LAJ O'Neill), Cambridge, UK: Cambridge University Press
-
Schneider ED, Kay JJ. 1995 Order from disorder: the thermodynamics of complexity in biology. In What is life? The next fifty years (eds MP Murphy, LAJ O'Neill), pp. 161-174. Cambridge, UK: Cambridge University Press.
-
(1995)
What Is Life? The Next Fifty Years
, pp. 161-174
-
-
Schneider, E.D.1
Kay, J.J.2
-
51
-
-
59649097680
-
Giant boid snake from the Palaeocene neotropics reveals hotter past equatorial temperatures
-
doi:10.1038/nature07671
-
Head JJ, Bloch JI, Hastings AK, Bourque JR, Cadena EA, Herrera FA, Polly PD, Jaramillo CA. 2009 Giant boid snake from the Palaeocene neotropics reveals hotter past equatorial temperatures. Nature 457, 715-717. (doi:10.1038/ nature07671)
-
(2009)
Nature
, vol.457
, pp. 715-717
-
-
Head, J.J.1
Bloch, J.I.2
Hastings, A.K.3
Bourque, J.R.4
Cadena, E.A.5
Herrera, F.A.6
Polly, P.D.7
Jaramillo, C.A.8
-
53
-
-
0002037156
-
Darwinism and developmental systems
-
(eds S Oyama, PE Griffiths, RD Gray), Cambridge, MA: MIT Press
-
Griffiths PE, Gray RD. 2001 Darwinism and developmental systems. In Cycles of contingency: developmental systems and evolution (eds S Oyama, PE Griffiths, RD Gray), pp. 195-218. Cambridge, MA: MIT Press.
-
(2001)
Cycles of Contingency: Developmental Systems and Evolution
, pp. 195-218
-
-
Griffiths, P.E.1
Gray, R.D.2
-
54
-
-
0015595829
-
Preservation of normal behavior by enucleated cells in culture
-
doi:10.1073/pnas.70.3.750
-
Goldman RD, Pollack R, Hopkins NH. 1973 Preservation of normal behavior by enucleated cells in culture. Proc. Natl Acad. Sci. USA 70, 750-754. (doi:10.1073/pnas.70.3.750)
-
(1973)
Proc. Natl Acad. Sci. USA
, vol.70
, pp. 750-754
-
-
Goldman, R.D.1
Pollack, R.2
Hopkins, N.H.3
-
55
-
-
0017150007
-
Studies on cell communication with enucleated human fibroblasts
-
doi:10.1083/jcb.71.3.693
-
Cox RP, Krauss MR, Balis ME, Dancis J. 1976 Studies on cell communication with enucleated human fibroblasts. J. Cell Biol. 71, 693-703. (doi:10.1083/jcb.71.3.693)
-
(1976)
J. Cell Biol.
, vol.71
, pp. 693-703
-
-
Cox, R.P.1
Krauss, M.R.2
Balis, M.E.3
Dancis, J.4
-
56
-
-
79251566511
-
Circadian clocks in human red blood cells
-
doi:10.1038/nature09702
-
O'Neill JS, Reddy AB. 2011 Circadian clocks in human red blood cells. Nature 469, 498-503. (doi:10.1038/nature09702)
-
(2011)
Nature
, vol.469
, pp. 498-503
-
-
O'Neill, J.S.1
Reddy, A.B.2
-
57
-
-
17244373578
-
Reconstitution of circadian oscillation of cyanobacterial KaiC phosphorylation in vitro
-
doi:10.1126/science.1108451
-
Nakajima M, Imai K, Ito H, Nishiwaki T, Murayama Y, Iwasaki H, Oyama T, Kondo T. 2005 Reconstitution of circadian oscillation of cyanobacterial KaiC phosphorylation in vitro. Science 308, 414-415. (doi:10.1126/science.1108451)
-
(2005)
Science
, vol.308
, pp. 414-415
-
-
Nakajima, M.1
Imai, K.2
Ito, H.3
Nishiwaki, T.4
Murayama, Y.5
Iwasaki, H.6
Oyama, T.7
Kondo, T.8
-
58
-
-
33845776522
-
Radiation tolerance in the tardigrade Milnesium tardigradum
-
doi:10.1080/09553000600972956
-
Horikawa DD et al. 2006 Radiation tolerance in the tardigrade Milnesium tardigradum. Int. J. Radiat. Biol. 82, 843-848. (doi:10.1080/09553000600972956)
-
(2006)
Int. J. Radiat. Biol.
, vol.82
, pp. 843-848
-
-
Horikawa, D.D.1
-
59
-
-
84880769081
-
Tolerance to gamma-irradiation in eggs of the tardigrade Richtersius coronifer depends on stage of development
-
doi:10.4081/jlimnol.2013.s1.e9
-
Jonsson KI, Beltran-Pardo E, Haghordoost S, Wojcic A, Bermudez-Cruz RM, Bernal-Villigas JE, Harms-Ringdahl M. 2013 Tolerance to gamma-irradiation in eggs of the tardigrade Richtersius coronifer depends on stage of development. J. Limnol. 72, 73-79. (doi:10.4081/jlimnol.2013.s1.e9)
-
(2013)
J. Limnol.
, vol.72
, pp. 73-79
-
-
Jonsson, K.I.1
Beltran-Pardo, E.2
Haghordoost, S.3
Wojcic, A.4
Bermudez-Cruz, R.M.5
Bernal-Villigas, J.E.6
Harms-Ringdahl, M.7
-
60
-
-
0035925393
-
The RNA/protein symmetry hypothesis: Experimental support for reverse translation of primitive proteins
-
doi:10.1006/jtbi.2000.2253
-
Nashimoto M. 2001 The RNA/protein symmetry hypothesis: experimental support for reverse translation of primitive proteins. J. Theor. Biol. 209, 181-187. (doi:10.1006/jtbi.2000.2253)
-
(2001)
J. Theor. Biol.
, vol.209
, pp. 181-187
-
-
Nashimoto, M.1
-
61
-
-
0017580932
-
The case for reverse translation
-
doi:10.1016/0022-5193(77)90116-3
-
Cook ND. 1977 The case for reverse translation. J. Theor. Biol. 64, 113-135. (doi:10.1016/0022-5193(77)90116-3)
-
(1977)
J. Theor. Biol.
, vol.64
, pp. 113-135
-
-
Cook, N.D.1
-
62
-
-
0014220631
-
Mechanism of biological memory
-
doi:10.1038/215481a0
-
Mekler LB. 1967 Mechanism of biological memory. Nature 215, 481-484. (doi:10.1038/215481a0)
-
(1967)
Nature
, vol.215
, pp. 481-484
-
-
Mekler, L.B.1
-
63
-
-
67650685282
-
More than 9,000,000 unique genes in human gut bacterial community: Estimating gene numbers inside a human body
-
doi:10.1371/journal.pone.0006074
-
Yang X, Xie L, Li Y, Wei C. 2009 More than 9,000,000 unique genes in human gut bacterial community: estimating gene numbers inside a human body. PLoS ONE 4, e6074. (doi:10.1371/journal.pone.0006074)
-
(2009)
PLoS ONE
, vol.4
-
-
Yang, X.1
Xie, L.2
Li, Y.3
Wei, C.4
-
64
-
-
0002748956
-
Bacteria as multicellular organisms
-
doi:10.1038/scientificamerican0688-82
-
Shapiro JA. 1988 Bacteria as multicellular organisms. Sci. Am. 258, 82-89. (doi:10.1038/scientificamerican0688-82)
-
(1988)
Sci. Am.
, vol.258
, pp. 82-89
-
-
Shapiro, J.A.1
-
65
-
-
1842612577
-
Bacterial biofilms: From the natural environment to infectious diseases
-
doi:10.1038/nrmicro821
-
Hall-Stoodley L, Costerton JW, Stoodley P. 2004 Bacterial biofilms: from the natural environment to infectious diseases. Nat. Rev. Microbiol. 2, 95-108. (doi:10.1038/nrmicro821)
-
(2004)
Nat. Rev. Microbiol.
, vol.2
, pp. 95-108
-
-
Hall-Stoodley, L.1
Costerton, J.W.2
Stoodley, P.3
-
66
-
-
65649083396
-
The jellyfish joyride: Causes, consequences and management responses to a more gelatinous future
-
doi:10.1016/j.tree.2009.01.010
-
Richardson AJ, Bakun A, Hays GC, Gibbons MJ. 2009 The jellyfish joyride: causes, consequences and management responses to a more gelatinous future. Trends Ecol. Evol. 24, 312-322. (doi:10.1016/j.tree.2009.01.010)
-
(2009)
Trends Ecol. Evol.
, vol.24
, pp. 312-322
-
-
Richardson, A.J.1
Bakun, A.2
Hays, G.C.3
Gibbons, M.J.4
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