-
1
-
-
34247391483
-
Multiple paths to a drug resistance phenotype: Mutations, translocations, deletions and amplification of coding genes or promoter regions, epigenetic changes and microRNAs
-
Fojo, T. Multiple Paths to a Drug Resistance Phenotype: Mutations, Translocations, Deletions and Amplification of Coding Genes or Promoter Regions, Epigenetic Changes and microRNAs. Drug. Resist. Updat. 2007, 10, 59-67.
-
(2007)
Drug. Resist. Updat.
, vol.10
, pp. 59-67
-
-
Fojo, T.1
-
2
-
-
25644461068
-
International lung cancer trends by histologic type: Male: Female differences diminishing and adenocarcinoma rates rising
-
Devesa, S.S.; Bray, F.I.; Vizcaino, A.P.; Parkin, D.M. International Lung Cancer Trends by Histologic Type: Male: Female Differences Diminishing and Adenocarcinoma rates rising. Int. J. Cancer. 2005, 117, 294-299.
-
(2005)
Int. J. Cancer.
, vol.117
, pp. 294-299
-
-
Devesa, S.S.1
Bray, F.I.2
Vizcaino, A.P.3
Parkin, D.M.4
-
3
-
-
0034767957
-
Cancer burden in the year 2000: The global picture
-
Parkin, D.M.; Bray, F.I.; Devasa, S.S. Cancer Burden in the Year 2000: The Global Picture. Eur. J. Cancer. 2001, 37(Suppl 8), S4-66.
-
(2001)
Eur. J. Cancer.
, vol.37
, Issue.SUPPL. 8
-
-
Parkin, D.M.1
Bray, F.I.2
Devasa, S.S.3
-
4
-
-
24644507578
-
Retrospective review of lung cancer patients with pleural dissemination after limited operations combined with parietal pleurectomy
-
Ohta, Y.; Shimizu, Y.; Matsumoto, I.; Tamura, M.; Oda, M.; Watanabe, G. Retrospective Review of Lung Cancer Patients with Pleural Dissemination after Limited Operations Combined with Parietal Pleurectomy. J. Surg. Oncol. 2005, 91, 237-242.
-
(2005)
J. Surg. Oncol.
, vol.91
, pp. 237-242
-
-
Ohta, Y.1
Shimizu, Y.2
Matsumoto, I.3
Tamura, M.4
Oda, M.5
Watanabe, G.6
-
5
-
-
34247521899
-
Lung cancer epidemiology and etiology
-
st ed.; Travis, W.D.; Brambilla, E.; Müller-Hermelink, H.K.; Harris, C.C., Eds.; IARC Press: Lyon, France, Ch. 1
-
st ed.; Travis, W.D.; Brambilla, E.; Müller-Hermelink, H.K.; Harris, C.C., Eds.; IARC Press: Lyon, France, 2004; Ch. 1, 12-15.
-
(2004)
World Health Organization Classification of Tumors. Pathology and Genetics. Tumors of the Lung, Pleura, Thymus, and Heart
, pp. 12-15
-
-
Parkin, M.1
Tyczynski, J.E.2
Bottetta, P.3
Samet, J.4
Shields, P.5
Caporaso, N.6
-
6
-
-
0012381722
-
Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell-lung cancer
-
Fukuoka, M.; Yano, S.; Giaccone, G.; Tamura, T.; Nakagawa, K.; Douillard, J.Y.; Nishiwaki, Y.; Vansteenkiste, J.; Kudoh, S.; Rischin, D.; Eek, R.; Horai, T.; Noda, K.; Takata, I.; Smit, E.; Averbuch, S.; Macleod, A.; Feyereislova, A.; Dong, R.P.; Baselga, J. Multi-Institutional Randomized Phase II Trial of Gefitinib for Previously Treated Patients with Advanced Non-Small-Cell-Lung Cancer. J. Clin. Oncol. 2003, 21, 2237-2246.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 2237-2246
-
-
Fukuoka, M.1
Yano, S.2
Giaccone, G.3
Tamura, T.4
Nakagawa, K.5
Douillard, J.Y.6
Nishiwaki, Y.7
Vansteenkiste, J.8
Kudoh, S.9
Rischin, D.10
Eek, R.11
Horai, T.12
Noda, K.13
Takata, I.14
Smit, E.15
Averbuch, S.16
MacLeod, A.17
Feyereislova, A.18
Dong, R.P.19
Baselga, J.20
more..
-
7
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez, J.G.; Jänne, P.A.; Lee, J.C.; Tracy, S.; Greulich, H.; Gabriel, S.; Herman, P.; Kaye, F.J.; Lindeman, N.; Boggon, T.J.; Naoki, K.; Sasaki, H.; Fujii, Y.; Eck, M.J.; Sellers, W.R.; Johnson, B.E.; Meyerson, M. EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy. Science 2004, 304, 1497-1500.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Jänne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
Gabriel, S.6
Herman, P.7
Kaye, F.J.8
Lindeman, N.9
Boggon, T.J.10
Naoki, K.11
Sasaki, H.12
Fujii, Y.13
Eck, M.J.14
Sellers, W.R.15
Johnson, B.E.16
Meyerson, M.17
-
8
-
-
33749606016
-
Usefulness of EGFR mutation screening in pleural fluid to predict the clinical outcome of gefitinib treated patients with lung cancer
-
Soh, J.; Toyooka, S.; Aoe, K.; Asano, H.; Ichihara, S.; Katayama, H.; Hiraki, A.; Kiura, K.; Aoe, M.; Sano, Y.; Sugi, K.; Shimizu, N.; Date, H. Usefulness of EGFR Mutation Screening in Pleural Fluid to Predict the Clinical Outcome of Gefitinib Treated Patients with Lung Cancer. Int. J. Cancer 2006, 119, 2353-2358.
-
(2006)
Int. J. Cancer
, vol.119
, pp. 2353-2358
-
-
Soh, J.1
Toyooka, S.2
Aoe, K.3
Asano, H.4
Ichihara, S.5
Katayama, H.6
Hiraki, A.7
Kiura, K.8
Aoe, M.9
Sano, Y.10
Sugi, K.11
Shimizu, N.12
Date, H.13
-
9
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch, T.J.; Bell, D.W.; Sordella, R.; Gurubhagavatula, S.; Okimoto, R.A.; Brannigan, B.W.; Harris, P.L.; Haserlat, S.M.; Supko, J.G.; Haluska, F.G.; Louis, D.N.; Christiani, D.C.; Settleman, J.; Haber, D.A. Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non-Small-Cell Lung Cancer to Gefitinib. N. Engl. J. Med. 2004, 350, 2129-2139.
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
Brannigan, B.W.6
Harris, P.L.7
Haserlat, S.M.8
Supko, J.G.9
Haluska, F.G.10
Louis, D.N.11
Christiani, D.C.12
Settleman, J.13
Haber, D.A.14
-
10
-
-
18244371651
-
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
-
Pao, W.; Miller, V.A.; Politi, K.A.; Riely, G.J.; Somwar, R.; Zakowski, M.F.; Kris, M.G.; Varmus, H. Acquired Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib is Associated with a Second Mutation in the EGFR Kinase Domain. PLoS. Med. 2005, 2, 73.
-
(2005)
PLoS. Med.
, vol.2
, pp. 73
-
-
Pao, W.1
Miller, V.A.2
Politi, K.A.3
Riely, G.J.4
Somwar, R.5
Zakowski, M.F.6
Kris, M.G.7
Varmus, H.8
-
11
-
-
34249810645
-
KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer
-
Massarelli, E.; Varella-Garcia, M.; Tang, X.; Xavier, A.C.; Ozburn, N.C.; Liu, D.D.; Bekele, B.N.; Herbst, R.S.; Wistuba, I.I. KRAS Mutation is an Important Predictor of Resistance to Therapy with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors In Non-Small-Cell Lung Cancer. Clin. Cancer Res. 2007, 13, 2890-2896.
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 2890-2896
-
-
Massarelli, E.1
Varella-Garcia, M.2
Tang, X.3
Xavier, A.C.4
Ozburn, N.C.5
Liu, D.D.6
Bekele, B.N.7
Herbst, R.S.8
Wistuba, I.I.9
-
12
-
-
78449268612
-
EGFR promotes lung tumorigenesis by activating miR-7 through a ras/ERK/Myc pathway that targets the ets2 transcriptional repressor ERF
-
Chou, Y.T.; Lin, H.H.; Lien, Y.C.; Wang, Y.H.; Hong, C.F.; Kao, Y.R.; Lin, S.C.; Chang, Y.C.; Lin, S.Y.; Chen, S.J.; Chen, H.C.; Yeh, S.D.; Wu, C.W. EGFR Promotes Lung Tumorigenesis by Activating miR-7 through a Ras/ERK/Myc Pathway that Targets the Ets2 Transcriptional Repressor ERF. Cancer. Res. 2010, 70, 8822-8831.
-
(2010)
Cancer. Res.
, vol.70
, pp. 8822-8831
-
-
Chou, Y.T.1
Lin, H.H.2
Lien, Y.C.3
Wang, Y.H.4
Hong, C.F.5
Kao, Y.R.6
Lin, S.C.7
Chang, Y.C.8
Lin, S.Y.9
Chen, S.J.10
Chen, H.C.11
Yeh, S.D.12
Wu, C.W.13
-
13
-
-
0028955388
-
Epidermal growth factor-related peptides and their receptors in human malignancies
-
Salomon, D.S.; Brandt, R.; Ciardiello, F.; Normanno, N. Epidermal Growth Factor-Related Peptides and Their Receptors in Human Malignancies. Crit. Rev. Oncol. Hematol. 1995, 19, 183-232.
-
(1995)
Crit. Rev. Oncol. Hematol.
, vol.19
, pp. 183-232
-
-
Salomon, D.S.1
Brandt, R.2
Ciardiello, F.3
Normanno, N.4
-
14
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from "Never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
-
Pao, W.; Miller, V.; Zakowski, M.; Doherty, J.; Politi, K.; Sarkaria, I.; Singh, B.; Heelan, R.; Rusch, V.; Fulton, L.; Mardis, E.; Kupfer, D.; Wilson, R.; Kris, M.; Varmus, H. EGF Receptor Gene Mutations are Common in Lung Cancers from "Never Smokers" and are Associated with Sensitivity of Tumors to Gefitinib and Erlotinib. Proc. Natl. Acad. Sci. USA. 2004, 101, 13306-13311.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.3
Doherty, J.4
Politi, K.5
Sarkaria, I.6
Singh, B.7
Heelan, R.8
Rusch, V.9
Fulton, L.10
Mardis, E.11
Kupfer, D.12
Wilson, R.13
Kris, M.14
Varmus, H.15
-
15
-
-
69949186250
-
Screening for epidermal growth factor receptor mutations in lung cancer
-
Spanish Lung Cancer Group
-
Rosell, R.; Moran, T.; Queralt, C.; Porta, R.; Cardenal, F.; Camps, C.; Majem, M.; Lopez-Vivanco, G.; Isla, D.; Provencio, M.; Insa, A.; Massuti, B.; Gonzalez-Larriba J.L.; Paz-Ares, L.; Bover, I.; Garcia-Campelo, R.; Moreno, M.A.; Catot, S.; Rolfo, C.; Reguart, N.; Palmero, R.; Sánchez, J.M.; Bastus, R.; Mayo, C.; Bertran-Alamillo, J.; Molina, M.A.; Sanchez, J.J.; Taron, M.; Spanish Lung Cancer Group. Screening for Epidermal Growth Factor Receptor Mutations in Lung Cancer. N. Engl. J. Med. 2009, 361, 958-967.
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 958-967
-
-
Rosell, R.1
Moran, T.2
Queralt, C.3
Porta, R.4
Cardenal, F.5
Camps, C.6
Majem, M.7
Lopez-Vivanco, G.8
Isla, D.9
Provencio, M.10
Insa, A.11
Massuti, B.12
Gonzalez-Larriba, J.L.13
Paz-Ares, L.14
Bover, I.15
Garcia-Campelo, R.16
Moreno, M.A.17
Catot, S.18
Rolfo, C.19
Reguart, N.20
Palmero, R.21
Sánchez, J.M.22
Bastus, R.23
Mayo, C.24
Bertran-Alamillo, J.25
Molina, M.A.26
Sanchez, J.J.27
Taron, M.28
more..
-
16
-
-
63049132774
-
First-line gefitinib for patients with advanced non-small-cell lung cancer harboring epidermal growth factor receptor mutations without indication for chemotherapy
-
North East Japan Gefitinib Study Group
-
Inoue, A; Kobayashi, K.; Usui, K.; Maemondo, M.; Okinaga, S.; Mikami, I.; Ando, M.; Yamazaki, K.; Saijo, Y.; Gemma, A.; Miyazawa, H.; Tanaka, T.; Ikebuchi, K.; Nukiwa, T.; Morita, S.; Hagiwara, K.; North East Japan Gefitinib Study Group. First-Line Gefitinib for Patients with Advanced Non-Small-Cell Lung Cancer Harboring Epidermal Growth Factor Receptor Mutations without Indication for Chemotherapy. J. Clin. Oncol. 2009, 27, 1394-1400.
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 1394-1400
-
-
Inoue, A.1
Kobayashi, K.2
Usui, K.3
Maemondo, M.4
Okinaga, S.5
Mikami, I.6
Ando, M.7
Yamazaki, K.8
Saijo, Y.9
Gemma, A.10
Miyazawa, H.11
Tanaka, T.12
Ikebuchi, K.13
Nukiwa, T.14
Morita, S.15
Hagiwara, K.16
-
17
-
-
84863755081
-
Gefitinib in non-small cell lung cancer
-
Costanzo, R.; Piccirillo, M.C.; Sandomenico, C.; Carillio, G.; Montanino, A.; Daniele, G.; Giordano, P.; Bryce, J.; De Feo, G.; Di Maio, M.; Rocco, G.; Normanno, N.; Perrone, F.; Morabito, A. Gefitinib in Non-Small Cell Lung Cancer. J. Biomed. Biotechnol. 2011, 8, 152-169.
-
(2011)
J. Biomed. Biotechnol.
, vol.8
, pp. 152-169
-
-
Costanzo, R.1
Piccirillo, M.C.2
Sandomenico, C.3
Carillio, G.4
Montanino, A.5
Daniele, G.6
Giordano, P.7
Bryce, J.8
De Feo, G.9
Di Maio, M.10
Rocco, G.11
Normanno, N.12
Perrone, F.13
Morabito, A.14
-
18
-
-
33744508879
-
Bax, bcl-2 and c-kit expression in non-small cell lung cancer and their effects on prognosis
-
Yaren, A.; Oztop, I.; Kargi, A.; Ulukus, C.; Onen, A.; Sanli, A.; Binicier, O.; Yilmaz, U.; Alakavuklar, M. Bax, bcl-2 and c-kit Expression in Non-Small Cell Lung Cancer and Their Effects on Prognosis. Int. J. Clin. Pract. 2006, 60, 675-682.
-
(2006)
Int. J. Clin. Pract.
, vol.60
, pp. 675-682
-
-
Yaren, A.1
Oztop, I.2
Kargi, A.3
Ulukus, C.4
Onen, A.5
Sanli, A.6
Binicier, O.7
Yilmaz, U.8
Alakavuklar, M.9
-
19
-
-
36749029619
-
Distinctive expression pattern of erbb family receptors signifies an aggressive variant of bladder cancer
-
Kassouf, W.; Black, P.C.; Tuziak, T.; Bondaruk, J.; Lee, S.; Brown, G.A.; Adam, L.;Wei, C.; Baggerly, K.; Bar-Eli, M.; McConkey, D.; Czerniak, B.; Dinney, C.P. Distinctive Expression Pattern of ErbB Family Receptors Signifies an Aggressive Variant of Bladder Cancer. J. Urol. 2008, 179, 353-358.
-
(2008)
J. Urol.
, vol.179
, pp. 353-358
-
-
Kassouf, W.1
Black, P.C.2
Tuziak, T.3
Bondaruk, J.4
Lee, S.5
Brown, G.A.6
Adam, L.7
Wei, C.8
Baggerly, K.9
Bar-Eli, M.10
McConkey, D.11
Czerniak, B.12
Dinney, C.P.13
-
20
-
-
0024326947
-
Isolation and characterization of ERBB3, a third member of ERBB/Epidermal growth factor receptor family: Evidence for overexpression in a subset of human mammary tumors
-
Kraus, M.H.; Issing, W.; Miki, T.; Popescu, N.C.; Aaronson, S.A. Isolation and Characterization of ERBB3, a Third Member of ERBB/Epidermal Growth Factor Receptor Family: Evidence for Overexpression in a Subset of Human Mammary Tumors. Proc. Natl. Acad. Sci. USA 1989, 86, 9193-9197.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 9193-9197
-
-
Kraus, M.H.1
Issing, W.2
Miki, T.3
Popescu, N.C.4
Aaronson, S.A.5
-
21
-
-
0034778447
-
EGFR and cancer prognosis
-
Nicholson, R.I.; Gee, J.M.; Harper, M.E. EGFR and Cancer Prognosis. Eur. J. Cancer. 2001, 37(Suppl. 4), S9-15.
-
(2001)
Eur. J. Cancer.
, vol.37
, Issue.SUPPL. 4
-
-
Nicholson, R.I.1
Gee, J.M.2
Harper, M.E.3
-
22
-
-
3242720345
-
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
-
Cunningham, D.; Humblet, Y.; Siena, S.; Khayat, D.; Bleiberg, H.; Santoro, A.; Bets, D.; Mueser, M.; Harstrick, A.; Verslype, C.; Chau, I.; Van Cutsem, E. Cetuximab Monotherapy and Cetuximab Plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal Cancer. N. Engl. J. Med. 2004, 351, 337-345.
-
(2004)
N. Engl. J. Med.
, vol.351
, pp. 337-345
-
-
Cunningham, D.1
Humblet, Y.2
Siena, S.3
Khayat, D.4
Bleiberg, H.5
Santoro, A.6
Bets, D.7
Mueser, M.8
Harstrick, A.9
Verslype, C.10
Chau, I.11
Van Cutsem, E.12
-
23
-
-
77951239766
-
Gene expression profiles of lung adenocarcinoma linked to histopathological grading and survival but not to EGF-R status: A microarray study
-
Neumann, J.; Feuerhake, F.; Kayser, G.; Wiech, T.; Aumann, K.; Passlick, B.; Fisch, P.; Werner, M.; Zur Hausen A. Gene Expression Profiles of Lung Adenocarcinoma Linked to Histopathological Grading and Survival but not to EGF-R Status: A Microarray Study. BMC Cancer 2010, 10, 77.
-
(2010)
BMC Cancer
, vol.10
, pp. 77
-
-
Neumann, J.1
Feuerhake, F.2
Kayser, G.3
Wiech, T.4
Aumann, K.5
Passlick, B.6
Fisch, P.7
Werner, M.8
Zur Hausen, A.9
-
24
-
-
0038461104
-
Epidermal growth factor receptor (EGFR) as a target in cancer therapy: Understanding the role of receptor expression and other molecular determinants that could influence the response to anti-EGFR drugs
-
Ciardiello, F.; Tortora, G. Epidermal Growth Factor Receptor (EGFR) as a Target in Cancer Therapy: Understanding the Role of Receptor Expression and Other Molecular Determinants that Could Influence the Response to Anti-EGFR Drugs. Eur. J. Cancer 2003, 39, 1348-1354.
-
(2003)
Eur. J. Cancer
, vol.39
, pp. 1348-1354
-
-
Ciardiello, F.1
Tortora, G.2
-
25
-
-
19844375720
-
Epidermal growth factor receptor mutations in non-small-cell lung cancer: Implications for treatment and tumor biology
-
Jänne, P.A.; Engelman, J.A.; Johnson, B.E. Epidermal Growth Factor Receptor Mutations in Non-Small-Cell Lung Cancer: Implications for Treatment and Tumor Biology. J. Clin. Oncol. 2005, 23, 3227-3234.
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 3227-3234
-
-
Jänne, P.A.1
Engelman, J.A.2
Johnson, B.E.3
-
26
-
-
67649421099
-
Expression of ABC transporters, p53, bax, bcl-2 in an archival sample of non-small cell lung cancer bearing a deletion in the EGFR gene
-
Amoêdo, N.; Castelo-Branco, M.; Paschoal, M.; Pezzuto, P.; Esperança, A.B.; Rumjanek, V.M.; Rumjanek, F.D. Expression of ABC Transporters, p53, Bax, Bcl-2 in an Archival Sample of Non-Small Cell Lung Cancer Bearing a Deletion in the EGFR gene. Int. J. Mol. Med. 2009, 23, 609-614.
-
(2009)
Int. J. Mol. Med.
, vol.23
, pp. 609-614
-
-
Amoêdo, N.1
Castelo-Branco, M.2
Paschoal, M.3
Pezzuto, P.4
Esperança, A.B.5
Rumjanek, V.M.6
Rumjanek, F.D.7
-
27
-
-
69949126786
-
Personalized medicine and inhibition of EGFR signaling in lung cancer
-
Gazdar, A.F. Personalized Medicine and Inhibition of EGFR Signaling in Lung Cancer. N. Engl. J. Med. 2009, 361, 1018-1020.
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 1018-1020
-
-
Gazdar, A.F.1
-
28
-
-
33646576196
-
Ethnic differences in response to epidermal growth factor receptor tyrosine kinase inhibitors
-
Calvo, E.; Baselga, J. Ethnic Differences in Response to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors. J. Clin. Oncol. 2006, 24, 2158-2163.
-
(2006)
J. Clin. Oncol.
, vol.24
, pp. 2158-2163
-
-
Calvo, E.1
Baselga, J.2
-
29
-
-
33744472217
-
Significance of EGFR protein expression and gene amplification in non-small cell lung carcinoma
-
Dacic, S.; Flanagan, M.; Cieply, K.; Ramalingam, S.; Luketich, J.; Belani, C.; Yousem, S.A. Significance of EGFR Protein Expression and Gene Amplification in Non-Small Cell Lung Carcinoma. Am. J. Clin. Pathol. 2006, 125, 860-865.
-
(2006)
Am. J. Clin. Pathol.
, vol.125
, pp. 860-865
-
-
Dacic, S.1
Flanagan, M.2
Cieply, K.3
Ramalingam, S.4
Luketich, J.5
Belani, C.6
Yousem, S.A.7
-
30
-
-
33645761156
-
Clinical implications of EGFR expression in the development and progression of solid tumors: Focus on non-small cell lung cancer
-
Ettinger, D.S. Clinical Implications of EGFR Expression in the Development and Progression of Solid Tumors: Focus on Non-Small Cell Lung Cancer. Oncologist 2006, 11, 358-373.
-
(2006)
Oncologist
, vol.11
, pp. 358-373
-
-
Ettinger, D.S.1
-
31
-
-
68949201629
-
Activating and resistance mutations of EGFR in non-small-cell lung cancer: Role in clinical response to EGFR tyrosine kinase inhibitors
-
Gazdar, A.F. Activating and Resistance Mutations of EGFR in Non-Small-Cell Lung Cancer: Role in Clinical Response to EGFR Tyrosine Kinase Inhibitors. Oncogene 2009, 28, 24-31.
-
(2009)
Oncogene
, vol.28
, pp. 24-31
-
-
Gazdar, A.F.1
-
32
-
-
33947502512
-
Lung cancer in never smokers: A review
-
Subramanian, J.; Govindan, R. Lung Cancer in Never Smokers: A Review. J. Clin. Oncol. 2007, 25, 561-570.
-
(2007)
J. Clin. Oncol.
, vol.25
, pp. 561-570
-
-
Subramanian, J.1
Govindan, R.2
-
33
-
-
45849137072
-
Molecular genetics of lung cancer in people who have never smoked
-
Subramanian, J.; Govindan, R. Molecular Genetics of Lung Cancer in People who have Never Smoked. Lancet Oncol. 2008, 9, 676-682.
-
(2008)
Lancet Oncol.
, vol.9
, pp. 676-682
-
-
Subramanian, J.1
Govindan, R.2
-
34
-
-
40849147041
-
EGFR antagonists in cancer treatment
-
Ciardiello, F.; Tortora, G. EGFR Antagonists in Cancer Treatment. N. Engl. J. Med. 2008, 358, 1160-1174.
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 1160-1174
-
-
Ciardiello, F.1
Tortora, G.2
-
35
-
-
52749099497
-
Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: A systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer
-
Linardou, H.; Dahabreh, I.J.; Kanaloupiti, D.; Siannis, F.; Bafaloukos, D.; Kosmidis, P.; Papadimitriou, C.A.; Murray, S. Assessment of Somatic k-RAS Mutations as a Mechanism Associated with Resistance to EGFR-Targeted Agents: A Systematic Review and Meta-Analysis of Studies in Advanced Non-Small-Cell Lung Cancer and Metastatic Colorectal Cancer. Lancet Oncol. 2008, 9, 962-972.
-
(2008)
Lancet Oncol.
, vol.9
, pp. 962-972
-
-
Linardou, H.1
Dahabreh, I.J.2
Kanaloupiti, D.3
Siannis, F.4
Bafaloukos, D.5
Kosmidis, P.6
Papadimitriou, C.A.7
Murray, S.8
-
36
-
-
18644377457
-
The role of EGF-R expression on patient survival in lung cancer: A systematic review with meta-analysis
-
Meert, A.P.; Martin, B.; Delmotte, P.; Berghmans, T.; Lafitte, J.J.; Mascaux, C.; Paesmans, M.; Steels, E.; Verdebout, J.M.; Sculier, J.P. The Role of EGF-R Expression on Patient Survival in Lung Cancer: A Systematic Review with Meta-Analysis. Eur. Respir. J. 2002, 20, 975-981.
-
(2002)
Eur. Respir. J.
, vol.20
, pp. 975-981
-
-
Meert, A.P.1
Martin, B.2
Delmotte, P.3
Berghmans, T.4
Lafitte, J.J.5
Mascaux, C.6
Paesmans, M.7
Steels, E.8
Verdebout, J.M.9
Sculier, J.P.10
-
37
-
-
32544443644
-
Survival impact of epidermal growth factor receptor overexpression in patients with non-small cell lung cancer: A meta-analysis
-
Nakamura, H.; Kawasaki, N.; Taguchi, M.; Kabasawa, K. Survival Impact of Epidermal Growth Factor Receptor Overexpression in Patients with Non-Small Cell Lung Cancer: A Meta-Analysis. Thorax 2006, 61, 140-145.
-
(2006)
Thorax
, vol.61
, pp. 140-145
-
-
Nakamura, H.1
Kawasaki, N.2
Taguchi, M.3
Kabasawa, K.4
-
38
-
-
33846970552
-
Epigenetic inactivation of EGFR by CpG island hypermethylation in cancer
-
Montero, A.J.; Diaz-Montero, C.M.; Mao, L.; Youssef, E.M.; Estecio, M.; Shen, L.; Issa, J.P. Epigenetic Inactivation of EGFR by CpG Island Hypermethylation in Cancer. Cancer. Biol. Ther. 2006, 5, 1494-1501.
-
(2006)
Cancer. Biol. Ther.
, vol.5
, pp. 1494-1501
-
-
Montero, A.J.1
Diaz-Montero, C.M.2
Mao, L.3
Youssef, E.M.4
Estecio, M.5
Shen, L.6
Issa, J.P.7
-
39
-
-
84869209119
-
DNA methylation biomarkers offer improved diagnostic efficiency in lung cancer
-
Nikolaidis, G.; Raji, O.; Markopoulou, S.; Gosney, J.R.; Bryan, J.;Warburton, C.;Walshaw, M.; Sheard, J.; Field, J.K.; Liloglou, T. DNA Methylation Biomarkers Offer Improved Diagnostic Efficiency in Lung Cancer. Cancer. Res. 2012, 72, 5692-5701.
-
(2012)
Cancer. Res.
, vol.72
, pp. 5692-5701
-
-
Nikolaidis, G.1
Raji, O.2
Markopoulou, S.3
Gosney, J.R.4
Bryan, J.5
Warburton, C.6
Walshaw, M.7
Sheard, J.8
Field, J.K.9
Liloglou, T.10
-
40
-
-
84862572356
-
Defining a gene promoter methylation signature in sputum for lung cancer risk assessment
-
Leng, S.; Do, K.; Yingling, M.C.; Picchi, M.A.; Wolf, H.J.; Kennedy, T.C.; Feser, W.J.; Baron, A.E.; Franklin, W.A.; Brock, M.V.; Herman, J.G.; Baylin, S.B.; Byers, T.; Stidley, C.A.; Belinsky, S.A. Defining a Gene Promoter Methylation Signature in Sputum for Lung Cancer Risk Assessment. Clin. Cancer. Res. 2012, 18, 3387-3395.
-
(2012)
Clin. Cancer. Res.
, vol.18
, pp. 3387-3395
-
-
Leng, S.1
Do, K.2
Yingling, M.C.3
Picchi, M.A.4
Wolf, H.J.5
Kennedy, T.C.6
Feser, W.J.7
Baron, A.E.8
Franklin, W.A.9
Brock, M.V.10
Herman, J.G.11
Baylin, S.B.12
Byers, T.13
Stidley, C.A.14
Belinsky, S.A.15
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