Individualized IMRT treatment approach for cervical lymph node metastases of unknown primary

Strahlentherapie und Onkologie

Volumn 190, Issue 4, 2014, Pages 386-393

  Janssen, S ^a   Glanzmann, C ^a   Huber, G ^a   Studer, G ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Cetuximab; Cisplatin; Neoplasm metastasis, unknown primary; Radiotherapy, intensity modulated; Treatment outcome

Indexed keywords

CETUXIMAB; CISPLATIN; DOCETAXEL; FLUOROURACIL;

ADULT; AGED; ARTICLE; CANCER OF UNKNOWN PRIMARY SITE; CANCER RECURRENCE; CERVICAL LYMPH NODE; COMPUTER ASSISTED TOMOGRAPHY; DISTANT METASTASIS FREE SURVIVAL; FEMALE; FOLLOW UP; HUMAN; INTENSITY MODULATED RADIATION THERAPY; LYMPH NODE METASTASIS; MALE; MIDDLE AGED; OROPHARYNX TUMOR; OVERALL SURVIVAL; RADIATION DOSE;

AGED; AGED, 80 AND OVER; DOSE FRACTIONATION; FEMALE; HUMANS; INDIVIDUALIZED MEDICINE; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASMS, UNKNOWN PRIMARY; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RADIOTHERAPY, CONFORMAL; SURVIVAL RATE; TUMOR BURDEN;

EID: 84896950686     PISSN: 01797158     EISSN: 1439099X     Source Type: Journal    
DOI: 10.1007/s00066-013-0508-x     Document Type: Article

References (30)

1. Wallace A, Richards GM, Harari PM et al (2011) Head and neck squamous cell carcinoma from an unknown primary site. Am J Otolaryngol 32:286-290
2. Jereczek-Fossa BA, Jassem J, Orecchia R (2004) Cervical lymph node metastases of squamous cell carcinoma from an unknown primary. Cancer Treat Rev 30:153-164 (Pubitemid 38418053)
3. Balaker AE, Abemayor E, Elashoff D, St John MA (2012) Cancer of unknown primary: does treatment modality make a difference? Laryngoscope 122:1279-1282
4. Strojan P, Ferlito A, Medina JE et al (2013) Contemporary management of lymph node metastases from an unknown primary to the neck: I. A review of diagnostic approaches. Head Neck 35:123-132
5. Reddy SP, Marks JE (1997) Metastatic carcinoma in the cervical lymph nodes from an unknown primary site: results of bilateral neck plus mucosal irradiation vs. ipsilateral neck irradiation. Int J Radiat Oncol Biol Phys 37:797-802 (Pubitemid 27181311)
6. Beldi D, Jereczek-Fossa BA, D'Onofrio A et al (2007) Role of radiotherapy in the treatment of cervical lymph node metastases from an unknown primary site: retrospective analysis of 113 patients. Int J Radiat Oncol Biol Phys 69:1051-1058 (Pubitemid 47625836)
7. Grau C, Johansen LV, Jakobsen J et al (2000) Cervical lymph node metastases from unknown primary tumours - results from a national survey by the Danish Society for Head and Neck Oncology. Radiother Oncol 55:121-129 (Pubitemid 30229986)
8. Ligey A, Gentil J, Crehange G et al (2009) Impact of target volumes and radiation technique on loco-regional control and survival for patients with unilateral cervical lymph node metastases from an unknown primary. Radiother Oncol 93:483-487
9. Fakhrian K, Thamm R, Knapp S et al (2012) Radio(chemo)therapy in the management of squamous cell carcinoma of cervical lymph nodes from an unknown primary site. A retrospective analysis. Strahlenther Onkol 188:56-61
10. Nieder C, Gregoire V, Ang KK (2001) Cervical lymph node metastases from occult squamous cell carcinoma: cut down a tree to get an apple? Int J Radiat Oncol Biol Phys 50:727-733 (Pubitemid 32515327)
11. Barker CA, Morris CG, Mendenhall WM (2005) Larynx-sparing radiotherapy for squamous cell carcinoma from an unknown head and neck primary site. Am J Clin Oncol 28:445-448 (Pubitemid 41437380)
12. Lee N, Puri DR, Blanco AI, Chao KS (2007) Intensity-modulated radiation therapy in head and neck cancers: an update. Head Neck 29:387-400 (Pubitemid 46623504)
13. Chen AM, Li BQ, Farwell DG et al (2011) Improved dosimetric and clinical outcomes with intensity-modulated radiotherapy for head-and-neck cancer of unknown primary origin. Int J Radiat Oncol Biol Phys 79:756-762
14. Chen AM, Farwell DG, Lau DH et al (2011) Radiation therapy in the management of head-and-neck cancer of unknown primary origin: how does the addition of concurrent chemotherapy affect the therapeutic ratio? Int J Radiat Oncol Biol Phys 81:346-352
15. Frank SJ, Rosenthal DI, Petsuksiri J et al (2010) Intensity-modulated radiotherapy for cervical node squamous cell carcinoma metastases from unknown head-and-neck primary site: M. D. Anderson Cancer Center outcomes and patterns of failure. Int J Radiat Oncol Biol Phys 78:1005-1010
16. Lu H, Yao M, Tan H (2009) Unknown primary head and neck cancer treated with intensity-modulated radiation therapy: to what extent the volume should be irradiated. Oral Oncol 45:474-479
17. Shoushtari A, Saylor D, Kerr KL et al (2011) Outcomes of patients with head-and-neck cancer of unknown primary origin treated with intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys 81:e83-e91
18. Villeneuve H, Despres P, Fortin B et al (2012) Cervical lymph node metastases from unknown primary cancer: a single-institution experience with intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys 82:1866-1871
19. Madani I, Vakaet L, Bonte K et al (2008) Intensity-modulated radiotherapy for cervical lymph node metastases from unknown primary cancer. Int J Radiat Oncol Biol Phys 71:1158-1166
20. Studer G, Huguenin PU, Davis JB et al (2006) IMRT using simultaneously integrated boost (SIB) in head and neck cancer patients. Radiat Oncol 1:7
21. Studer G, Furrer K, Davis BJ et al (2006) Postoperative IMRT in head and neck cancer. Radiat Oncol 1:40
22. Bonner JA, Harari PM, Giralt J et al (2006) Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 354:567-578 (Pubitemid 43209104)
23. Patel RS, Clark J, Wyten R et al (2007) Squamous cell carcinoma from an unknown head and neck primary site: a "selective treatment" approach. Arch Otolaryngol Head Neck Surg 133:1282-1287 (Pubitemid 350294260)
24. Eisbruch A, Marsh LH, Dawson LA et al (2004) Recurrences near base of skull after IMRT for head-and-neck cancer: implications for target delineation in high neck and for parotid gland sparing. Int J Radiat Oncol Biol Phys 59:28-42 (Pubitemid 38501504)
25. Eisbruch A, Foote RL, O'Sullivan B et al (2002) Intensity-modulated radiation therapy for head and neck cancer: emphasis on the selection and delineation of the targets. Semin Radiat Oncol 12:238-249 (Pubitemid 34755930)
26. Bernier J, Domenge C, Ozsahin M et al (2004) Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer. N Engl J Med 350:1945-1952 (Pubitemid 38580197)
27. Forastiere AA, Goepfert H, Maor M et al (2003) Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer. N Engl J Med 349:2091-2098 (Pubitemid 37464533)
28. Cooper JS, Pajak TF, Forastiere AA et al (2004) Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck. N Engl J Med 350:1937-1944
29. Christiansen H, Hermann RM, Martin A et al. Neck lymph node metastases from an unknown primary tumor retrospective study and review of literature. Strahlenther Onkol. 2005; 181: 355-356
30. Sher DJ, Balboni TA, Haddad RI et al. Efficacy and toxicity of chemoradiotherapy using intensity-modulated radiotherapy for unknown primary of head and neck. Int J Radiat Oncol Biol Phys. 2011; 80:1405-1411