Multivariate model for predicting postoperative blood loss in children undergoing cardiac surgery: A preliminary study

British Journal of Anaesthesia

Volumn 112, Issue 4, 2014, Pages 708-714

  Savan, V ^a   Willems, A ^b   Faraoni, D ^b   Van Der Linden, P ^b  

^a STATE UNIVERSITY OF MEDICINE AND PHARMACY NICOLAE TESTEMITANU   (Moldova)

^b HOP UNIV DES ENFANTS REINE FABIOLA   (Belgium)

Author keywords

children; congenital heart diseases; postoperative blood loss; risk factors

Indexed keywords

ADOLESCENT; ARTICLE; BLOOD VOLUME; BODY WEIGHT; CHILD; CYANOSIS; FEMALE; HEART SURGERY; HIGH RISK PATIENT; HUMAN; INTRAOPERATIVE PERIOD; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE HEMORRHAGE; PREOPERATIVE PERIOD; PRESCHOOL CHILD; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCHOOL CHILD; SENSITIVITY AND SPECIFICITY; WOUND CLOSURE;

CHILDREN; CONGENITAL HEART DISEASES; POSTOPERATIVE BLOOD LOSS; RISK FACTORS;

ADOLESCENT; ANESTHESIA, INTRAVENOUS; BODY WEIGHT; CHILD; CHILD, PRESCHOOL; CYANOSIS; FEMALE; HEART DEFECTS, CONGENITAL; HUMANS; INFANT; INFANT, NEWBORN; INTRAOPERATIVE CARE; MALE; MULTIVARIATE ANALYSIS; POSTOPERATIVE HEMORRHAGE; RETROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; TIME FACTORS; WOUND CLOSURE TECHNIQUES;

EID: 84896947498     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aet463     Document Type: Article

References (28)

1. Murphy GJ, Reeves BC, Rogers CA, Rizvi SI, Culliford L, Angelini GD. Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery. Circulation 2007; 116: 2544-52
2. Karkouti K, Wijeysundera DN, Yau TM, et al. The independent association of massive blood loss with mortality in cardiac surgery. Transfusion 2004; 44: 1453-62
3. Paparella D, Brister SJ, Buchanan MR. Coagulation disorders of cardiopulmonary bypass: A review. Intensive Care Med 2004; 30: 1873-81
4. OsthausWA, Boethig D, JohanningK, et al.Wholeblood coagulation measured by modified thrombelastography (ROTEM) is impaired in infants with congenital heart diseases. Blood Coagul Fibrinolysis 2008; 19: 220-5
5. Guzzetta NA. Benefits and risks of red blood cell transfusion in pediatric patients undergoing cardiac surgery. Paediatr Anaesth 2011; 21: 504-11
6. Miller BE, Guzzetta NA, Tosone SR, Levy JH. Rapid evaluation of coagulopathies after cardiopulmonary bypass in children using modified thromboelastography. Anesth Analg 2000; 90: 1324-30
7. Gorlinger K, Dirkmann D, Hanke AA, et al. First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery:aretrospective, single-center cohort study. Anesthesiology 2011; 115: 1179-91
8. Weber CF, Gorlinger K, Meininger D, et al. Point-of-care testing: A prospective, randomized clinical trial of efficacy in coagulopathic cardiac surgery patients. Anesthesiology 2012; 117: 531-47
9. Rahe-Meyer N, Hanke A, Schmidt DS, Hagl C, Pichlmaier M. Fibrinogen concentrate reduces intraoperative bleeding when used as first-line hemostatic therapy during major aortic replacement surgery: Results from a randomized, placebo-controlled trial. J Thorac Cardiovasc Surg 2013; 145: S178-85
10. Gombotz H, Knotzer H. Preoperative identification of patients with increased risk for perioperative bleeding. Curr Opin Anaesthesiol 2013; 26: 82-90
11. Despotis G, Avidan M, Eby C. Prediction and management of bleeding in cardiac surgery. J Thromb Haemost 2009; 7(Suppl. 1): 111-7
12. Jenkins KJ, Gauvreau K, Newburger JW, Spray TL, Moller JH, Iezzoni LI. Consensus-based method for risk adjustment for surgery for congenital heart disease. J Thorac Cardiovasc Surg 2002; 123: 110-8
13. Apfel CC, Laara E, Koivuranta M, Greim CA, Roewer N. A simplified risk score for predicting postoperative nausea and vomiting: Conclusions from cross-validations between two centers. Anesthesiology 1999; 91: 693-700
14. Johansson PI, Solbeck S, Genet G, Stensballe J, Ostrowski SR.Coagulopathy and hemostatic monitoring in cardiac surgery: An update. Scand Cardiovasc J 2012; 46: 194-202
15. Afshari A, Wikkelso A, Brok J, Moller AM, Wetterslev J. Thrombelastography (TEG) or thromboelastometry (ROTEM) to monitor haemotherapy versus usual care in patients with massive transfusion. Cochrane Database Syst Rev 2011; CD007871
16. Theusinger OM, Felix C, Spahn DR. Strategies to reduce the use of blood products: A European perspective. Curr Opin Anaesthesiol 2012; 25: 59-65
17. Hayashi T, Sakurai Y, Fukuda K, et al. Correlations between global clotting function tests, duration of operation, and postoperative chest tube drainage in pediatric cardiac surgery. Paediatr Anaesth 2011; 21: 865-71
18. Kontras SB, Sirak HD, NewtonWA Jr. Hematologic abnormalities in children with congenital heart disease. J AmMed Assoc 1966; 195: 611-5
19. Komp DM, Sparrow AW. Polycythemia in cyanotic heart disease-A study of altered coagulation. J Pediatr 1970; 76: 231-6
20. Tempe DK, Virmani S. Coagulation abnormalities in patients with cyanotic congenital heart disease. J Cardiothorac Vasc Anesth 2002; 16: 752-65
21. Jensen AS, Johansson PI, Bochsen L, et al. Fibrinogen function is impaired in whole blood from patients with cyanotic congenital heart disease. Int J Cardiol 2012, doi: 10.1016/j.ijcard.2012.06.019
22. Williams GD, Bratton SL, Riley EC, Ramamoorthy C. Association between age and blood loss in children undergoing open heart operations. Ann Thorac Surg 1998; 66: 870-5
23. Miller BE, Mochizuki T, Levy JH, et al. Predicting and treating coagulopathies after cardiopulmonary bypass in children. Anesth Analg 1997; 85: 1196-202
24. Petaja J, LundstromU, Leijala M, Peltola K, Siimes MA. Bleeding and use of blood products after heart operations in infants. J ThoracCardiovasc Surg 1995; 109: 524-9
25. Martinowitz U, Michaelson M. Israeli Multidisciplinary r FTF: Guidelines for the use of recombinant activated factor VII (rFVIIa) in uncontrolled bleeding: A report by the Israeli Multidisciplinary rFVIIa Task Force. J Thromb Haemost 2005; 3: 640-8
26. Kozek-Langenecker SA, Afshari A, Albaladejo P, et al. Management of severe perioperative bleeding: Guidelines from the European Society of Anaesthesiology. Eur J Anaesthesiol 2013; 30: 270-382
27. Rahe-Meyer N, Solomon C, Hanke A, et al. Effects of fibrinogen concentrate as first-line therapy during major aortic replacement surgery: A randomized, placebo-controlled trial. Anesthesiology 2013; 118: 40-50
28. Williams GD, Bratton SL, Ramamoorthy C. Factors associated with blood loss and blood product transfusions: A multivariate analysis in children after open-heart surgery. Anesth Analg 1999; 89: 57-64.