Maternal pre-pregnancy body mass index and offspring attention deficit hyperactivity disorder: A population-based cohort study using a sibling-comparison design

International Journal of Epidemiology

Volumn 43, Issue 1, 2014, Pages 83-90

  Chen, Qi ^a   Sjölander, Arvid ^a   Långström, Niklas ^a   Rodriguez, Alina ^b,c,d   Serlachius, Eva ^a   D'Onofrio, Brian M ^e   Lichtenstein, Paul ^a   Larsson, Henrik ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b MID SWEDEN UNIVERSITY   (Sweden)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e INDIANA UNIVERSITY   (United States)

Author keywords

Adhd; Confounding; Maternal BMI; Prenatal; Sibling comparison

Indexed keywords

AMPHETAMINE; ATOMOXETINE; DEXAMPHETAMINE; METHYLPHENIDATE;

BODY MASS; COHORT ANALYSIS; DATA SET; DESIGN; ESTIMATION METHOD; NUMERICAL MODEL; OBESITY; PREGNANCY; RISK FACTOR; WEIGHT;

ADULT; ARTICLE; ATTENTION DEFICIT DISORDER; BODY MASS; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; HAZARD RATIO; HUMAN; MAJOR CLINICAL STUDY; MALE; OBESITY; OUTCOME ASSESSMENT; POPULATION BASED CASE CONTROL STUDY; PREGNANCY; PRESCHOOL CHILD; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; PROSPECTIVE STUDY; SWEDEN; YOUNG ADULT; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; FOLLOW UP; HEALTH SURVEY; MATERNAL BEHAVIOR; MOTHER; MOTHER CHILD RELATION; PSYCHOLOGY; QUESTIONNAIRE; RISK FACTOR; SIBLING; STATISTICS AND NUMERICAL DATA;

SWEDEN;

ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; BODY MASS INDEX; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MATERNAL BEHAVIOR; MOTHER-CHILD RELATIONS; MOTHERS; OBESITY; POPULATION SURVEILLANCE; PREGNANCY; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; RISK FACTORS; SIBLINGS; SURVEYS AND QUESTIONNAIRES; SWEDEN;

EID: 84896894290     PISSN: 03005771     EISSN: 14643685     Source Type: Journal    
DOI: 10.1093/ije/dyt152     Document Type: Article

References (37)

1. Polanczyk G, de Lima MS, Horta BL, Biederman J, Rohde LA. The worldwide prevalence of ADHD: a systematic review and metaregression analysis. Am J Psychiatry 2007;164:942-48.
2. Biederman J, Monuteaux MC, Doyle AE et al. Impact of executive function deficits and attention-deficit/ hyperactivity disorder (ADHD) on academic outcomes in children. J Consult Clin Psychol 2004;72: 757-66.
3. Bukstein O. Substance use disorders in adolescents with attention-deficit/hyperactivity disorder. Adolesc Med State Art Rev 2008;19:242-53.
4. de Graaf R, Kessler RC, Fayyad J et al. The prevalence and effects of adult attention-deficit/hyperactivity disorder (ADHD) on the performance of workers: results from the WHO World Mental Health Survey Initiative. Occup Environ Med 2008;65:835-42.
5. Faraone SV, Perlis RH, Doyle AE et al. Molecular genetics of attention-deficit/hyperactivity disorder. Biol Psychiatry 2005;57:1313-23.
6. Linnet KM, Dalsgaard S, Obel C et al. Maternal lifestyle factors in pregnancy risk of attention deficit hyperactivity disorder and associated behaviors: review of the current evidence. Am J Psychiatry 2003;160:1028-40.
7. Banerjee TD, Middleton F, Faraone SV. Environmental risk factors for attention-deficit hyperactivity disorder. Acta Paediatr 2007;96:1269-74.
8. Bale TL, Baram TZ, Brown AS et al. Early life programming and neurodevelopmental disorders. Biol Psychiatry 2010;68:314-19.
9. Swanson JD, Wadhwa PM. Developmental origins of child mental health disorders. J Child Psychol Psychiatry 2008;49:1009-19.
10. Rees S, Harding R. Brain development during fetal life: influences of the intra-uterine environment. Neurosci Lett 2004;361:111-14.
11. Thapar A, Rutter M. Do prenatal risk factors cause psychiatric disorder? Be wary of causal claims. Br J Psychiatry 2009;195:100-01.
12. Rosenberg TJ, Garbers S, Lipkind H et al. Maternal obesity and diabetes as risk factors for adverse pregnancy outcomes: differences among 4 racial/ethnic groups. Am J Public Health 2005;95:1545-51.
13. Catalano PM. Obesity, insulin resistance, and pregnancy outcome. Reproduction 2010;140:365-71.
14. Van Lieshout RJ, Taylor VH, Boyle MH. Pre-pregnancy and pregnancy obesity and neurodevelopmental outcomes in offspring: a systematic review. Obes Rev 2011;12: e548-59.
15. Buss C, Entringer S, Davis EP et al. Impaired executive function mediates the association between maternal prepregnancy body mass index and child ADHD symptoms. PLoS One 2012;7:e37758.
16. Rodriguez A, Miettunen J, Henriksen TB et al. Maternal adiposity prior to pregnancy is associated with ADHD symptoms in offspring: evidence from three prospective pregnancy cohorts. Int J Obes (Lond) 2008;32:550-57.
17. Rodriguez A. Maternal pre-pregnancy obesity and risk for inattention and negative emotionality in children. J Child Psychol Psychiatry 2010;51:134-43.
18. Albayrak O, Putter C, Volckmar AL et al. Common obesity risk alleles in childhood attention-deficit/hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet 2013; 162:295-305.
19. Fernandes C, Grayton H, Poston L et al. Prenatal exposure to maternal obesity leads to hyperactivity in offspring. Mol Psychiatry 2012;17:1159-60.
20. West SG, Duan N, Pequegnat W et al. Alternatives to the randomized controlled trial. Am J Public Health 2008;98: 1359-66.
21. Rutter M. Proceeding From Observed Correlation to Causal Inference: The Use of Natural Experiments. Perspect Psychol Sci 2007;2:377-95.
22. Donovan SJ, Susser E. Commentary: Advent of sibling designs. Int J Epidemiol 2011;40:345-49.
23. Lahey BB, D'Onofrio BM. All in the Family: Comparing Siblings to Test Causal Hypotheses Regarding Environmental Influences on Behavior. Curr Dir Psychol Sci 2010; 19:319-23.
24. D'Onofrio BM, Lahey BB, Turkheimer E, Lichtenstein P. The critical need for family-based, quasi-experimental research in integrating genetic and social science research. Am J Public Health, in press.
25. The National Board of Health and Welfare. The Swedish Medical Birth Registry: A Summary of Content and Quality. Stockholm, Sweden: The National Board of Health and Welfare, 2003. http://www.socialstyrelsen.se/Lists/Artikelkatalog/Attachments/10655/2003-112-3_20031123.pdf (18 September 2013, date last accessed).
26. Sweden S. Multi-generation Register 2005 - A Description of Contents and Quality. Örebro, Sweden: Statistics Sweden, 2006.
27. Wettermark B, Hammar N, Fored CM et al. The new Swedish Prescribed Drug Register - opportunities for pharmacoepidemiological research and experience from the first six months. Pharmacoepidem Drug Saf 2007;16: 726-35.
28. Lundh A. On the Children's Global Assessement (CGAS). Stockholm, Sweden: Karolinska Institutet, 2012.
29. James PT, Leach R, Kalamara E, Shayeghi M. The worldwide obesity epidemic. Obes Res 2001;9(Suppl 4): S228-33.
30. Cortese S, Vincenzi B. Obesity and ADHD: Clinical and Neurobiological Implications. Curr Top Behav Neurosci 2012;9:199-218.
31. Campbell BC, Eisenberg D. Obesity, attention deficithyperactivity disorder and the dopaminergic reward system. Coll Antropol 2007;31:33-38.
32. Mitchell BF, Taggart MJ. Are animal models relevant to key aspects of human parturition? Am J Physiol Regul Integr Comp Physiol 2009;297:R525-45.
33. Jaffee SR, Strait LB, Odgers CL. From correlates to causes: can quasi-experimental studies and statistical innovations bring us closer to identifying the causes of antisocial behavior? Psychol Bull 2013;138:272-95.
34. Frisell T, Oberg S, Kuja-Halkola R, Sjolander A. Sibling comparison designs: bias from non-shared confounders and measurement error. Epidemiology 2012;23:713-20.
35. Schwartz MW, Woods SC, Seeley RJ et al. Is the energy homeostasis system inherently biased toward weight gain? Diabetes 2003;52:232-8.
36. Lee SI, Schachar RJ, Chen SX et al. Predictive validity of DSM-IV and ICD-10 criteria for ADHD and hyperkinetic disorder. J Child Psychol Psychiatry 2008;49:70-78.
37. Larsson H, Ryden E, Boman M, Langstrom N, Lichtenstein P, Landen M. Risk of bipolar disorder and schizophrenia in relatives of people with attention-deficit hyperactivity disorder. Br J Psychiatry 2013. doi:10.1192/ bjp.bp.112.120808.