Classification of and risk factors for estrogen deprivation pain syndromes related to aromatase inhibitor treatments in women with breast cancer: A prospective multicenter cohort study

Journal of Pain

Volumn 15, Issue 3, 2014, Pages 293-303

  Laroche, Francoise ^a   Coste, Joël ^b   Medkour, Terkia ^b   Cottu, Paul Henri ^c   Pierga, Jean Yves ^c   Lotz, Jean Pierre ^d   Beerblock, Karine ^d   Tournigand, Christophe ^a   Declèves, Xavier ^b   De Cremoux, Patricia ^e   Bouhassira, Didier ^f   Perrot, Serge ^b,f  

^a HÔPITAL SAINT ANTOINE   (France)

^b HÔTEL DIEU   (France)

^c INSTITUT CURIE   (France)

^d HÔPITAL TENON   (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

^f INSERM U 987   (France)

Author keywords

aromatase inhibitors; arthritis; Breast cancer; estrogen deprivation; pain

Indexed keywords

ANALGESIC AGENT; ANASTROZOLE; ANTHRACYCLINE DERIVATIVE; AROMATASE INHIBITOR; BIOLOGICAL MARKER; CODEINE; ESTROGEN; EXEMESTANE; LETROZOLE; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL; SEX HORMONE; TAXANE DERIVATIVE; TRAMADOL; VITAMIN D;

ADULT; AGED; ANXIETY; ARTHRALGIA; ARTICLE; BEHAVIOR DISORDER; BONE; BREAST CANCER; CANCER CHEMOTHERAPY; CANCER CLASSIFICATION; CANCER HORMONE THERAPY; CANCER PATIENT; CANCER RADIOTHERAPY; CLINICAL ASSESSMENT; COHORT ANALYSIS; CONTROLLED STUDY; DEMOGRAPHY; DEPRESSION; DISEASE CLASSIFICATION; DISEASE MARKER; DRUG EFFICACY; DRUG SAFETY; ENVIRONMENTAL FACTOR; FEMALE; FOLLOW UP; HEREDITY; HORMONE BLOOD LEVEL; HOT FLUSH; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; MIDDLE AGED; MULTICENTER STUDY; NEUROPATHIC PAIN; OXIDATIVE STRESS; PAIN; PAIN ASSESSMENT; PREDICTOR VARIABLE; PROSPECTIVE STUDY; QUALITY OF LIFE; RISK FACTOR; SIDE EFFECT; SINGLE NUCLEOTIDE POLYMORPHISM; SLEEP; SLEEP DISORDER; SOCIAL PSYCHOLOGY; TENDINITIS;

AROMATASE INHIBITORS; ARTHRITIS; BREAST CANCER; ESTROGEN DEPRIVATION; PAIN;

AGED; ANALGESICS; AROMATASE INHIBITORS; ARTHRALGIA; BREAST NEOPLASMS; ESTROGENS; FEMALE; FOLLOW-UP STUDIES; HUMANS; NEURALGIA; PAIN; PROGNOSIS; PROSPECTIVE STUDIES; RISK FACTORS; SYNDROME; TENDINOPATHY;

EID: 84896834645     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2013.11.004     Document Type: Article

References (45)

1. ATAC Trialists' Group Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early stage breast cancer: Results of the ATAC (Arimidex, Tamoxifen Alone or in Combination) randomised trial Lancet 359 2002 2131 2139
2. T.M. Atkinson, S. Halabi, A.V. Bennett, L. Rogak, L. Sit, Y. Li, E. Kaplan, and E. Basch Cancer and Leukemia Group B: Measurement of affective and activity pain interference using the Brief Pain Inventory (BPI): cancer and leukemia group B 70903 Pain Med 13 2012 1417 1424
3. I. Bjelland, A.A. Dahl, T.T. Haug, and D. Neckelmann The validity of the Hospital Anxiety and Depression Scale. An updated literature review J Psychosom Res 52 2002 69 77
4. D. Bouhassira, N. Attal, H. Alchaar, F. Boureau, B. Brochet, J. Bruxelle, G. Cunin, J. Fermanian, P. Ginies, A. Grun-Overdyking, H. Jafari-Schluep, M. Lantéri-Minet, B. Laurent, G. Mick, A. Serrie, D. Valade, and E. Vicaut Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4) Pain 114 2005 29 36
5. Breast International Group (BIG) 1-98 Collaborative Group A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer N Engl J Med 353 2005 2747 2757
6. J.D. Caldwell, and G.F. Jirikowski Sex hormone binding globulin and aging Horm Metab Res 41 2009 173 182
7. J.A. Cauley, C.K. Kwoh, G. Egeland, M.C. Nevitt, L. Cooperstein, J. Rohay, A. Towers, and J.P. Gutai Serum sex hormones and severity of osteoarthritis of the hand J Rheumatol 20 1993 1170 1175
8. T.C. Cheng, S.T. Chen, C.S. Huang, Y.P. Fu, J.C. Yu, C.W. Cheng, P.E. Wu, and C.Y. Shen Breast cancer risk associated with genotype polymorphism of the catechol estrogen-metabolizing genes: A multigenic study on cancer susceptibility Int J Cancer 113 2005 345 353
9. C.S. Cleeland, and K.M. Ryan Pain assessment: Global use of the Brief Pain Inventory Ann Acad Med Singapore 23 1994 129 138
10. C.R. Cloninger, D.M. Svrakic, and T.R. Przybeck A psychobiological model of temperament and character Arch Gen Psychiatry 50 1993 975 990
11. C.R. Cloninger, T.R. Przybeck, D.M. Svrakic, and R.D. Wetzel The Temperament and Character Inventory (TCI): A Guide to Its Development and Use 1994 Center for Psychobiology of Personality, Washington University St Louis, MO
12. R.E. Coleman, W.W. Bolten, M. Lansdown, S. Dale, C. Jackisch, D. Merkel, N. Maass, and P. Hadji Aromatase inhibitor-induced arthralgia: Clinical experience and treatment recommendations Cancer Treat Rev 104 2007 87 91
13. R.C. Coombes, E. Hall, L.J. Gibson, R. Paridaens, J. Jassem, T. Delozier, S.E. Jones, I. Alvarez, G. Bertelli, O. Ortmann, A.S. Coates, E. Bajetta, D. Dodwell, R.E. Coleman, L.J. Fallowfield, E. Mickiewicz, J. Andersen, P.E. Lønning, G. Cocconi, A. Stewart, N. Stuart, C.F. Snowdon, M. Carpentieri, G. Massimini, J.M. Bliss, C. van de Velde, and Intergroup Exemestane Study A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer N Engl J Med 350 2004 1081 1092
14. K.D. Crew, H. Greenlee, J. Capodice, G. Raptis, L. Brafman, D. Fuentes, A. Sierra, and D.L. Hershman Prevalence of joint symptoms in postmenopausal women taking aromatase inhibitors for early-stage breast cancer J Clin Oncol 25 2007 3877 3883
15. O.S. Din, D. Dodwell, M.C. Winter, S. Mori, and R.E. Coleman Current opinion of aromatase inhibitor-induced arthralgia in breast cancer in the UK Clin Oncol 23 2011 674 680
16. N. Fortunati, M.G. Catalano, G. Boccuzzi, and R. Frairia Sex Hormone-Binding Globulin (SHBG), estradiol and breast cancer Mol Cell Endocrinol 316 2010 86 92
17. J. Ferlay, D.M. Parkin, and E. Steliarova-Foucher Estimates of cancer incidence and mortality in Europe in 2008 Eur J Cancer 46 2010 765 781
18. C.A. Haiman, L. Dossus, V.W. Setiawan, D.O. Stram, A.M. Dunning, G. Thomas, M.J. Thun, D. Albanes, D. Altshuler, E. Ardanaz, H. Boeing, J. Buring, N. Burtt, E.E. Calle, S. Chanock, F. Clavel-Chapelon, G.A. Colditz, D.G. Cox, H.S. Feigelson, S.E. Hankinson, R.B. Hayes, B.E. Henderson, J.N. Hirschhorn, R. Hoover, D.J. Hunter, R. Kaaks, L.N. Kolonel, L. Le Marchand, P. Lenner, E. Lund, S. Panico, P.H. Peeters, M.C. Pike, E. Riboli, A. Tjonneland, R. Travis, D. Trichopoulos, S. Wacholder, and R.G. Ziegler Genetic variation at the CYP19A1 locus predicts circulating estrogen levels but not breast cancer risk in postmenopausal women Cancer Res 67 2007 1893 1897
19. G.A. Hawker, S. Mian, T. Kendzerska, and M. French Measures of adult pain Arthritis Care Res 63 2011 S240 S252
20. K.J. Helzlsouer, L. Gallicchio, R. MacDonald, B. Wood, and E. Rushovich A prospective study of aromatase inhibitor therapy, vitamin D, C-reactive protein and musculoskeletal symptoms Breast Cancer Res Treat 131 2012 277 285
21. N.L. Henry, D. Pchejetski, R. A'Hern, A.T. Nguyen, P. Charles, J. Waxman, L. Li, A.M. Storniolo, D.F. Hayes, D.A. Flockhart, V. Stearns, and J. Stebbing Inflammatory cytokines and aromatase inhibitor-associated musculoskeletal syndrome: A case-control study Br J Cancer 103 2010 291 296
22. N.L. Henry, J.T. Giles, D. Ang, M. Mohan, D. Dadabhoy, J. Robarge, J. Hayden, S. Lemler, K. Shahverdi, P. Powers, L. Li, D. Flockhart, V. Stearns, D.F. Hayes, A.M. Storniolo, and D.J. Clauw Prospective characterization of musculoskeletal symptoms in early-stage breast cancer patients treated with aromatase inhibitors Breast Cancer Res Treat 111 2008 365 372
23. R. Josse Roles of estrogen in bone loss and arthralgia during aromatase inhibitor treatment Curr Opin Oncol 19 Suppl 1 2007 S1 S8
24. H. Kim, D.P. Mittal, M.J. Iadarola, and R.A. Dionne Genetic predictors for acute experimental cold and heat pain sensitivity in humans J Med Genet 43 2006 e40
25. M. Laroche, S. Borg, S. Lassoued, B. De Lafontan, and H. Roché Joint pain with aromatase inhibitors: Abnormal frequency of Sjögren syndrome J Rheumatol 34 2007 2259 2263
26. J.J. Mao, C. Stricker, D. Bruner, S. Xie, M.A. Bowman, J.T. Farrar, B.T. Greene, and A. DeMichele Patterns and risk factors associated with aromatase inhibitor-related arthralgia among breast cancer survivors Cancer 115 2009 3631 3639
27. B.S. McEwen, K.T. Akama, J.L. Spencer-Segal, T.A. Milner, and E.M. Waters Estrogen effects on the brain: actions beyond the hypothalamus via novel mechanisms Behav Neurosci 126 2012 4 16
28. H. Merskey, and N. Bogduk Classification of Chronic Pain II ed. 1994 IASP Task Force on Taxonomy, IASP Press Seattle, WA
29. J.S. Mieog, J.P. Morden, J.M. Bliss, R.C. Coombes, and C.J. van de Velde IES Steering Committee: Carpal tunnel syndrome and musculoskeletal symptoms in postmenopausal women with early breast cancer treated with exemestane or tamoxifen after 2-3 years of tamoxifen: A retrospective analysis of the intergroup exemestane study Lancet Oncol 13 2012 420 432
30. L. Morales, S. Pans, K. Verschueren, B. Van Calster, R. Paridaens, R. Westhovens, D. Timmerman, L. De Smet, I. Vergote, M.R. Christiaens, and P. Neven Prospective study to assess short-term intra-articular and tenosynovial changes in the aromatase inhibitor-associated arthralgia syndrome J Clin Oncol 26 2008 3147 3152
31. G. Moxley Rheumatic disorders and functional disability with aromatase inhibitor therapy Clin Breast Cancer 10 2010 144 147
32. P. Niravath Aromatase inhibitors induced arthralgia: A review Ann Oncol 00 2013 1 7
33. A. Pelissolo, L. Mallet, J.M. Baleyte, G. Michel, C.R. Cloninger, J.F. Allilaire, and R. Jouvent The Temperament and Character Inventory-Revised (TCI-R): Psychometric characteristics on the French version Acta Psychiatr Scand 112 2005 126 133
34. C.A. Presant, L. Bosserman, T. Young, M. Vakil, R. Horns, G. Upadhyaya, B. Ebrahimi, C. Yeon, and F. Howard Aromatase inhibitor-associated arthralgia and/or bone pain: Frequency and characterization in non-clinical trial patients Clin Breast Cancer 7 2007 775 778
35. A. Robidoux, E. Rich, N.J. Bureau, S. Mader, D. Laperrière, M. Bail, N. Tremblay, M. Patenaude, and J. Turgeon A prospective pilot investigating the musculoskeletal pain in breast cancer patients receiving aromatase inhibitor therapy Curr Oncol 18 2011 285 294
36. I. Sestak, J. Cuzick, F. Sapunar, R. Eastell, J.F. Forbes, A.R. Bianco, and A.U. Buzdar ATAC Trialists' Group: Risk factors for joint symptoms in patients enrolled in the ATAC trial: A retrospective, exploratory analysis Lancet Oncol 9 2008 866 872
37. I. Sestak, F. Sapunar, and J. Cuzick Aromatase inhibitor-induced carpal tunnel syndrome: Results from the ATAC trial J Clin Oncol 27 2009 4961 4965
38. O. Singer, T. Cigler, A.B. Moore, A.B. Levine, K. Hentel, L. Belfi, H.T. Do, and L.A. Mandl Defining the aromatase inhibitor musculoskeletal syndrome: A prospective study Arthritis Care Res 64 2012 1910 1918
39. S. Singh, J. Cuzick, D. Mesher, B. Richmond, and A. Howell Effect of baseline serum vitamin D levels on aromatase inhibitor-induced musculoskeletal symptoms: results from the IBIS-II chemoprevention study using anastrozole Breast Cancer Res Treat 132 2012 625 629
40. E.M. Smets, B. Garssen, B. Bonke, and J.C. De Haes The Multidimensional Fatigue Inventory (MFI) psychometric qualities of an instrument to assess fatigue J Psychosom Res 39 1995 315 325
41. M.A. Sprangers, M. Groenvold, J.I. Arraras, J. Franklin, A. te Velde, M. Muller, L. Franzini, A. Williams, H.C. de Haes, P. Hopwood, A. Cull, and N.K. Aaronson The European Organization for Research and Treatment of Cancer breast cancer-specific quality-of-life questionnaire module: First results from a three-country field study J Clin Oncol 14 1996 2756
42. M.J.L. Sullivan, S. Bishop, and J. Pivik The Pain Catastrophizing Scale: Development and validation Psychol Assess 7 1995 432 524
43. T. Ushiyama, H. Ueyama, K. Inoue, I. Ohkubo, and S. Hukuda Expression of genes for estrogen receptors alpha and beta in human articular chondrocytes Osteoarthritis Cartilage 7 1999 560 566
44. F. Wolfe, H.A. Smythe, M.B. Yunus, R.M. Bennett, C. Bombardier, D.L. Goldenberg, P. Tugwell, S.M. Campbell, M. Abeles, P. Clark, A.G. Fam, S.J. Farber, J.J. Flechtner, C.M. Franklin, R.A. Gatter, D. Hamaty, J. Lessard, A.S. Lichtbroun, A.T. Masi, G.A. McCain, W.J. Reynolds, T.J. Romano, I.J. Russell, and R.P. Sheon The American College of Rheumatology 1990 criteria for the classification of fibromyalgia: Report of the Multicenter Criteria Committee Arthritis Rheum 33 1990 160 172
45. J. Xu, M. Bartoces, A.V. Neale, R.K. Dailey, J. Northrup, and K.L. Schwartz Natural history of menopause symptoms in primary care patients: A MetroNet Study J Am Board Fam Pract 18 2005 374 382