Optimization of Ultrasound-Assisted Extraction of Artemisinin from Artemisia annua L. by Response Surface Methodology

Separation Science and Technology (Philadelphia)

Volumn 49, Issue 5, 2014, Pages 673-681

  Zhang, Haihui ^a   Zhang, Li ^a   Hu, Xigui ^b   Zhou, Yonghong ^a   Ding, Chunbang ^a   Yang, Ruiwu ^a   Wang, Xiaoli ^a   Li, Dengchao ^a  

^a SICHUAN AGRICULTURAL UNIVERSITY   (China)

^b HENAN INSTITUTE OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Artemisia annua L; artemisinin; optimization; parameters; response surface methodology; ultrasound assisted extraction

Indexed keywords

LINEAR REGRESSION; OPTIMIZATION; PYRENE; SURFACE PROPERTIES;

ARTEMISIA ANNUA; ARTEMISININ; PARAMETERS; RESPONSE SURFACE METHODOLOGY; ULTRASOUND-ASSISTED EXTRACTION;

EXTRACTION;

EID: 84896827140     PISSN: 01496395     EISSN: 15205754     Source Type: Journal    
DOI: 10.1080/01496395.2013.862545     Document Type: Article

References (36)

1. Klayman, D.L. (1985) Qinghaosu (artemisinin): An antimalarial drug from China. Science, 228 (4703): 1049.
2. Quispe-Condori, S.; Sánchez, D.; Foglio, M.A.; Rosa, P.T.V.; Zetzl, C.; Brunner, G.; Meireles, M.A.A. (2005) Global yield isotherms and kinetic of artemisinin extraction from Artemisia annua L. leaves using supercritical carbon dioxide. J. Supercrit. Fluid., 36 (1): 40.
3. Ro, D.K.; Paradise, E.M.; Ouellet, M.; Fisher, K.J.; Newman, K.L.; Ndungu, J.M.; Ho, K.A.; Eachus, R.A.; Ham, T.S.; Kirby, J.; Chang, M.C.Y.; Withers, S.T.; Shiba, Y.; Sarpong, R.; Keasling, J.D. (2006) Production of the antimalarial drug precursor artemisinic acid in engineered yeast. Nature, 440: 940.
4. Roll Back Malaria. (2005) World Malaria Report 2005. World Health Organization and UNICEF WHO/HTM/MAL/2005.1102 Geneva.
5. Bhakuni, R.S.; Jain, D.C.; Sharma, R.P.; Kumar, S. (2001) Secondary metabolites of Artemisia annua and their biological activity. Curr. Sci., 80 (1): 35.
6. Laughlin, J.C.; Heazlewood, G.N.; Beattie, B.M. (2002) Cultivation of Artemisia annua L., ed., 18th; Taylor & Francis: London, U.K.
7. Zhou, Y.P.; Zhao, M.; Zhou, Z.Q. (2006) State of the study on Artemisia annua resources. Terr. Nat. Res. Stud., (3): 93
8. Bloland, P.B. (2001) Drug resistance in malaria. World Health Organization WHO/CDS/CSR/DRS/2001.4, Geneva.
9. Enserink, M. (2005) Infectious diseases: Source of new hope against malaria is in short supply. Science, 307 (5706): 33.
10. Ravindranathan, T.; Kumar M. A.; Menon R. B.; Hiremath S. V. (1990) Stereoselective synthesis of artemisinin. Tetrahedron Lett., 31 (5): 755.
11. Covello, P.S. (2008) Making artemisinin. Phytochemistry, 69 (17): 2881.
12. Dabiri, M.; Salimi S.; Ghassempour A.; Rassouli A.; Talebi M. (2005) Optimization of microwave-assisted extraction for alizarin and purpurin in Rubiaceae plants and its comparison with conventional extraction methods. J. Sep. Sci., 28 (4): 387.
13. Hao, J.Y.; Han, W.; Huang, S.D.; Xue, B.Y.; Deng, X. (2002) Microwave-assisted extraction of artemisinin from Artemisia annua L. Sep. Purif. Technol., 28 (3): 191.
14. Lin, Y.L.; Yang, C.C.; Hsu, H.K.; Hsu, S.L.; Chang, C.M.J. (2006) Response surface methodology to supercritical fluids extraction of artemisinin and the effects on rat hepatic stellate cell in vitro. J. Supercrit. Fluid., 39 (1): 48.
15. Wang, L.J.; Weller, C.L. (2006) Recent advances in extraction of nutraceuticals from plants. Trends. Food. Sci. Tech., 17 (6): 300.
16. Jalali-Heravi, M.; Parastar H.; Ebrahimi-Najafabadi H. (2009) Characterization of volatile components of Iranian saffron using factorial-based response surface modeling of ultrasonic extraction combined with gas chromatography-mass spectrometry analysis. J. Chromatogr. A., 1216 (33): 6088
17. Veličković, D.T.; Milenović, D.M.; Ristić, M.S.; Veljković, V.B. (2006) Kinetics of ultrasonic extraction of extractive substances from garden (Salvia officinalis L.) and glutinous (Salvia glutinosa L.) sage. Ultrason. Sonochem., 13 (2): 150.
18. Vinatoru, M.; Toma, M.; Radu, O.; Filip, P.I.; Lazurca, D.; Mason T. J. (1997) The use of ultrasonic for the extraction of bioactive principles from plant materials. Ultrason. Sonochem., 4 (2): 135.
19. Li, Z.X.; Wang, X.H.; Lei, Y.L.; Jiang H. J.; Liu, D.Y. (2007) Study on extraction of artemisinin enhanced with ultrasonic wave. J. Sichuan Univ. Sci. Eng., 20 (2): 92.
20. Wang, X.; Zhao, X.E.; Yang, B.; Dong, H.J.; Liu, D.H.; Huang, L.Q. (2011) Combination of ultrasonic-assisted extraction with RRLC-QQQ method for the determination of artemisinin in the Chinese herb Artemisia annua L. Phytochem. Anal., 22 (3): 280.
21. Myers, R. H.; Montgomery D. C. (1995). Response Surface Methodology: Process and Product Optimization using Designed Experiment ed., 1st; Wiley: New York
22. Tabaraki, R.; Nateghi A. (2011) Optimization of ultrasonic-assisted extraction of natural antioxidants from rice bran using response surface methodology. Ultrason. Sonochem., 18 (6): 1279.
23. Gunaraj, V.; Murugan, N. (1999) Application of response surface methodologies for predicting weld base quality in submerged arc welding of pipes. J. Mater. Process. Tech., 88 (1-3): 266.
24. Zou, Y.F.; Chen, X.F.; Yang, W.Y.; Liu S. (2011) Response surface methodology for optimization of the ultrasonic extraction of polysaccharides from Codonopsis pilosula Nannf. var. modesta L. T. Shen. Carbohyd. Polym., 84 (1): 503.
25. Rodrigues, S.; Pinto, G.A.S.; Fernandes F. A. N. (2008) Optimization of ultrasound extraction of phenolic compounds from coconut (Cocos nucifera) shell powder by response surface methodology. Ultrason. Sonochem., 15 (1): 95.
26. Zhang, H.F.; Yang, X.H.; Zhao, L.D.; Wang, Y. (2009) Ultrasonic-assisted extraction of epimedin C from fresh leaves of Epimedium and extraction mechanism. Innov. Food. Sci. Emerg., 10 (1): 54.
27. Eh, A.L.S.; Teoh S. G. (2012) Novel modified ultrasonication technique for the extraction of lycopene from tomatoes. Ultrason. Sonochem., 19 (1): 151.
28. Box, G.E.P.; Behnken, D.W. (1960) Some new three level designs for the study of quantitative variables. Technometrics, 2 (4): 455.
29. Zhao, B.; Wang, Y. C.; Wu, J.; Ou-Yang F. (2000). Extraction of artemisinin enhanced with ultrasonic wave. Eng. Chem. Metall., 21 (3): 310.
30. Qian, G.P.; Yang, Y.W.; Ren Q. L. (2005) Determination of artemisinin in Artemisia annua L. by reversed phase HPLC. J. Liq. Chromatogr. R. T. 28 (5): 705.
31. Christen, P.; Veuthey, J.L. (2001) New trends in extraction, identification and quantification of artemisinin and its derivatives. Curr. Med. Chem., 8 (15): 1827.
32. Yan, Y.L; Yu, C.H.; Chen, J.; Li, X.X.; Wang, W.; Li S. Q. (2011) Ultrasonic-assisted extraction optimized by response surface methodology, chemical composition and antioxidant activity of polysaccharides from Tremella mesenterica. Carbohyd. Polym., 83 (1): 217.
33. Zhong, K.; Wang, Q. (2010) Optimization of ultrasonic extraction of polysaccharides from dried longan pulp using response surface methodology. Carbohyd. Polym., 80 (1): 19.
34. Li, J.W., Ding, S.D., Ding X. L. (2007) Optimization of the ultrasonically assisted extraction of polysaccharides from Zizyphus jujuba cv. Jinsixiaozao J. Food. Eng., 80 (1): 176.
35. Tiwari, B.K.; Patras, A.; Brunton, N.; Cullen, P.J.; O'Donnell C. P. (2010) Effect of ultrasound processing on anthocyanins and color of red grape juice. Ultrason. Sonochem., 17 (3): 598.
36. Sadilova, E., Carle, R.; Stintzing, F.C. (2007) Thermal degradation of anthocyanins and its impact on color and in vitro antioxidant capacity. Mol. Nutr. Food. Res., 51 (12): 1461.