Biomarker interactions are better predictors of spontaneous preterm birth

Reproductive Sciences

Volumn 21, Issue 3, 2014, Pages 340-350

  Bhat, G ^a   Williams, S M ^b   Saade, G R ^a   Menon, Ramkumar ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

biomarker; mdr; preterm

Indexed keywords

ANGIOPOIETIN 2; BIOLOGICAL MARKER; INTERLEUKIN 2; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 3; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1;

AFRICAN AMERICAN; AMNION FLUID; ARTICLE; CAUCASIAN; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MATERNAL PLASMA; MULTIFACTOR DIMENSIONALITY REDUCTION; PREMATURE LABOR; PRIORITY JOURNAL; RACE DIFFERENCE; SPONTANEOUS PRETERM BIRTH; UMBILICAL CORD BLOOD;

BIOMARKER; MDR; PRETERM;

ADOLESCENT; ADULT; AFRICAN AMERICANS; AMNION; ANGIOPOIETIN-2; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; FETAL BLOOD; HUMANS; INFANT, NEWBORN; PREDICTIVE VALUE OF TESTS; PREGNANCY; PREMATURE BIRTH; TUMOR NECROSIS FACTOR-ALPHA; YOUNG ADULT;

EID: 84896821604     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719113497285     Document Type: Article

References (21)

1. Menon R. Spontaneous preterm birth, a clinical dilemma: etiologic, pathophysiologic and genetic heterogeneities and racial disparity. Acta Obstet Gynecol Scand. 2008; 87 (6). 590-600
2. Goldenberg RL, Culhane JF, Iams JD, Romero R. Epidemiology and causes of preterm birth. Lancet. 2008; 371 (9606). 75-84
3. Lockwood CJ. Testing for risk of preterm delivery. Clin Lab Med. 2003; 23 (2). 345-360
4. Romero R, Mazor M, Munoz H, Gomez R, Galasso M, Sherer DM. The preterm labor syndrome. Ann N Y Acad Sci. 1994; 734: 414-429
5. Beck S, Wojdyla D, Say L, et al. The worldwide incidence of preterm birth: a systematic review of maternal mortality and morbidity. Bull World Health Organ. 2010; 88 (1). 31-38
6. Simhan HN, Caritis SN. Prevention of preterm delivery. N Engl J Med. 2007; 357 (5). 477-487
7. Menon R, Torloni MR, Voltolini C, et al. Biomarkers of spontaneous preterm birth: an overview of the literature in the last four decades. Reprod Sci. 2011; 18 (11). 1046-1070
8. Tsiartas P, Holst RM, Wennerholm UB, et al. Prediction of spontaneous preterm delivery in women with threatened preterm labour: a prospective cohort study of multiple proteins in maternal serum. BJOG. 2012; 119 (12). 1544-1545
9. Hee L, Kirkegaard I, Vogel I, et al. Low serum interleukin-17 is associated with preterm delivery. Acta Obstet Gynecol Scand. 2011; 90 (1). 92-96
10. Jacobsson B, Holst RM, Mattsby-Baltzer I, Nikolaitchouk N, Wennerholm UB, Hagberg H. Interleukin-18 in cervical mucus and amniotic fluid: relationship to microbial invasion of the amniotic fluid, intra-amniotic inflammation and preterm delivery. BJOG. 2003; 110 (6). 598-603
11. Gervasi MT, Romero R, Bracalente G, et al. Midtrimester amniotic fluid concentrations of interleukin-6 and interferon-gamma-inducible protein-10: evidence for heterogeneity of intra-amniotic inflammation and associations with spontaneous early (<32 weeks) and late (>32 weeks) preterm delivery. J Perinat Med. 2012; 40 (4). 329-343
12. Holst RM, Hagberg H, Wennerholm UB, Skogstrand K, Thorsen P, Jacobsson B. Prediction of microbial invasion of the amniotic cavity in women with preterm labour: analysis of multiple proteins in amniotic and cervical fluids. BJOG. 2011; 118 (2). 240-249
13. Brou L, Almli LM, Pearce BD, et al. Dysregulated biomarkers induce distinct pathways in preterm birth. BJOG. 2012; 119 (4). 458-473
14. Ritche M, Hahn L, Roodi N, et al. Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer. Am J Hum Genet. 2001; 69 (1). 138-147
15. Hahn L, Ritchie M, Moore J. Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions. Bioinformatics. 2003; 19 (3). 376-382
16. MooreJason. Epistasis Blog. Computational Genetics Library. Institute of Quantitative Biomedical Sciences. The Geisel School of Medicine. Dartmouth College. http://compgen.blogspot.com/. Accessed January, 2012.
17. Menon R, Velez DR, Simhan H, et al. Multilocus interactions at maternal tumor necrosis factor-alpha, tumor necrosis factor receptors, interleukin-6 and interleukin-6 receptor genes predict spontaneous preterm labor in European-American women. Am J Obstet Gynecol. 2006; 194 (6). 1616-1624
18. Coffey CS, Herbert PR, Ritchie MD, et al. An application of conditional logistic regression and multifactor dimensionality reduction for detecting gene-gene interactions on risk of myocardial infarction: the importance of model validation. BMC Bioinformatics. 2004; 5: 49
19. Skol AD, Scott LJ, Abecasis GR, Boehnke M. Joint analysis is more efficient than replication-based analysis for two stage genome-wide association studies. Nat Genet. 2006; 38 (2). 209-213
20. Oggé G, Romero R, Lee DC, et al. Chronic chorioamnionitis displays distinct alterations of the amniotic fluid proteome. J Pathol. 2011; 223 (4). 553-565
21. Cobo T, Tsiartas P, Kacerovsky M, et al. Maternal inflammatory response to microbial invasion of the amniotic cavity: analyses of multiple proteins in the maternal serum. Acta Obstet Gynecol Scand. 2013; 92 (1). 61-68