메뉴 건너뛰기




Volumn 29, Issue 1, 2014, Pages 37-45

Present status and perspective of pharmacogenetics in Mexico

Author keywords

Cytochrome P450; Drug metabolizing enzymes; Interindividual variability; Pharmacogenetics; Phenotyping cocktails

Indexed keywords

CAFFEINE; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; DEXTROMETHORPHAN; DRUG METABOLIZING ENZYME; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; LOSARTAN; N ACYLTRANSFERASE 2 PROTEIN; OMEPRAZOLE; PROTEIN; UNCLASSIFIED DRUG;

EID: 84896782635     PISSN: 07925077     EISSN: None     Source Type: Journal    
DOI: 10.1515/dmdi-2013-0019     Document Type: Review
Times cited : (15)

References (40)
  • 1
    • 84896760258 scopus 로고    scopus 로고
    • Dirección General de Información en salud (DGIS). Sistema Nacional de Salud (SINAIS)
    • Dirección General de Información en salud (DGIS). Base de datos de defunciones generales 1979-2007. Sistema Nacional de Salud (SINAIS). Available at: http://www.sinais. salud.gob.mx.
    • Base de Datos de Defunciones Generales 1979-2007
  • 3
    • 78349239717 scopus 로고    scopus 로고
    • Prevalence and distribution of type 2 diabetes mellitus in Mexican adult population: A probabilistic survey
    • Villalpando S, De la Cruz V, Rojas R, Shamah T, Ávila M, Gaona B, et al. Prevalence and distribution of type 2 diabetes mellitus in Mexican adult population: a probabilistic survey. Salud Pública Mex 2010;52(Suppl):S19.
    • (2010) Salud Pública Mex , vol.52 , Issue.SUPPL.
    • Villalpando, S.1    De La Cruz, V.2    Rojas, R.3    Shamah, T.4    Ávila, M.5    Gaona, B.6
  • 5
    • 67649669143 scopus 로고    scopus 로고
    • Diabetes mellitus type 2: Sales of oral hypoglycemic agents and costs of the pharmacological treatments in Mexico
    • Martínez MA, Kravzov J, Moreno MR, Rubio C, Skromne D, Rivas M, et al. Diabetes mellitus type 2: sales of oral hypoglycemic agents and costs of the pharmacological treatments in Mexico. Rev Mex Cienc Farm 2007;38: 23-33.
    • (2007) Rev Mex Cienc Farm , vol.38 , pp. 23-33
    • Martínez, M.A.1    Kravzov, J.2    Moreno, M.R.3    Rubio, C.4    Skromne, D.5    Rivas, M.6
  • 6
    • 84859542292 scopus 로고    scopus 로고
    • Cost-effectiveness study of oral hypoglycemic agents in the treatment of outpatients with type 2 diabetes attending a public primary care clinic in Mexico City
    • Díaz C, Martínez MA, Kravzov J, Cárdenas MR, Moreno C, Martínez JM. Cost-effectiveness study of oral hypoglycemic agents in the treatment of outpatients with type 2 diabetes attending a public primary care clinic in Mexico City. Clinicoecon Outcomes Res 2012;4: 57-65.
    • (2012) Clinicoecon Outcomes Res , vol.4 , pp. 57-65
    • Díaz, C.1    Martínez, M.A.2    Kravzov, J.3    Cárdenas, M.R.4    Moreno, C.5    Martínez, J.M.6
  • 7
    • 84864288321 scopus 로고    scopus 로고
    • Search for the molecular basis of ultra-rapid CYP2C9-catalysed metabolism: Relationship between SNP IVS8-109A >t and the losartan metabolism phenotype in Swedes
    • Hatta F, Teh L, Hellden A, Hellgren K, Roh H, Salleh M, et al. Search for the molecular basis of ultra-rapid CYP2C9-catalysed metabolism: relationship between SNP IVS8-109A >T and the losartan metabolism phenotype in Swedes. Eur J Clin Pharmacol 2012;68: 1033-42.
    • (2012) Eur J Clin Pharmacol , vol.68 , pp. 1033-1042
    • Hatta, F.1    Teh, L.2    Hellden, A.3    Hellgren, K.4    Roh, H.5    Salleh, M.6
  • 8
    • 79953059565 scopus 로고    scopus 로고
    • CYP2C9 allele frequency differences between populations of Mexican Mestizo, Mexican-Tepehuano, and Spaniards
    • Dorado P, Sosa M, Peñas M, Alanis R, Wong L, Licinio J, et al. CYP2C9 allele frequency differences between populations of Mexican Mestizo, Mexican-Tepehuano, and Spaniards. Pharmacogenomics J 2011;11: 108-12.
    • (2011) Pharmacogenomics J , vol.11 , pp. 108-112
    • Dorado, P.1    Sosa, M.2    Peñas, M.3    Alanis, R.4    Wong, L.5    Licinio, J.6
  • 9
    • 0004943891 scopus 로고    scopus 로고
    • Ley General de Salud, 7 de febrero de
    • Ley General de Salud, Diario Oficial de la Federación, 7 de febrero de 1984:1-148. Available at: http://www.diputados.gob. mx/LeyesBiblio/pdf/142.pdf.
    • (1984) Diario Oficial de la Federación , pp. 1-148
  • 10
    • 0004943891 scopus 로고    scopus 로고
    • Reglamento de la Ley General de Salud en Material de Investigación para la Salud, 6 de enero de
    • Reglamento de la Ley General de Salud en Material de Investigación para la Salud, Diario Oficial de la Federación, 6 de enero de 1987:1-24. Available at: http://www.salud.gob.mx/ unidades/cdi/nom/compi/rlgsmis.html.
    • (1987) Diario Oficial de la Federación , pp. 1-24
  • 11
    • 0004943891 scopus 로고    scopus 로고
    • Reglamento de la Comisión Federal para la Protección contra Riesgos Sanitarios, 13 de abril de
    • Reglamento de la Comisión Federal para la Protección contra Riesgos Sanitarios, Diario Oficial de la Federación, 13 de abril de 2004:1-15. Available at: http://www.diputados.gob.mx/ LeyesBiblio/regla/29.PDF.
    • (2004) Diario Oficial de la Federación , pp. 1-15
  • 12
    • 67649616741 scopus 로고    scopus 로고
    • Pre-Hispanic mesoamerican demography approximates the present-day ancestry of mestizos throughout the territory of Mexico
    • Rubí R, Martínez G, Muñoz JF, González A, Cerda RM, Anaya M, et al. Pre-Hispanic mesoamerican demography approximates the present-day ancestry of mestizos throughout the territory of Mexico. Am J Phys Anthropol 2009;139: 284-94.
    • (2009) Am J Phys Anthropol , vol.139 , pp. 284-294
    • Rubí, R.1    Martínez, G.2    Muñoz, J.F.3    González, A.4    Cerda, R.M.5    Anaya, M.6
  • 13
    • 70349601143 scopus 로고    scopus 로고
    • Ancestry informative markers and admixture proportions in northeastern Mexico
    • Martínez M, Beuten J, Leach R, Parra E, Cruz M, Rangel H, et al. Ancestry informative markers and admixture proportions in northeastern Mexico. J Hum Genet 2009;54: 504-9.
    • (2009) J Hum Genet , vol.54 , pp. 504-509
    • Martínez, M.1    Beuten, J.2    Leach, R.3    Parra, E.4    Cruz, M.5    Rangel, H.6
  • 14
    • 48949084636 scopus 로고    scopus 로고
    • Genomic medicine in Mexico: Initial steps and the road ahead
    • Jiménez G, Silva I, Hidalgo A, March S. Genomic medicine in Mexico: initial steps and the road ahead. Genome Res 2008;18: 1191-8.
    • (2008) Genome Res , vol.18 , pp. 1191-1198
    • Jiménez, G.1    Silva, I.2    Hidalgo, A.3    March, S.4
  • 16
    • 36348997121 scopus 로고    scopus 로고
    • A haplotype analysis of CYP2E1 polymorphisms in relation to alcoholic phenotypes in Mexican Americans
    • Yang M, Tsuang J, Yvonne Y. A haplotype analysis of CYP2E1 polymorphisms in relation to alcoholic phenotypes in Mexican Americans. Alcohol Clin Exp Res 2007;31: 1991-2000.
    • (2007) Alcohol Clin Exp Res , vol.31 , pp. 1991-2000
    • Yang, M.1    Tsuang, J.2    Yvonne, Y.3
  • 18
    • 84896797392 scopus 로고    scopus 로고
    • Influence of admixture components on CYP2C9*2 allele frequency in eight indigenous populations from Northwest Mexico
    • Sosa-Macias M, Lazalde BP, Galaviz C, Rangel H, Salazar J, Martínez VM, et al. Influence of admixture components on CYP2C9*2 allele frequency in eight indigenous populations from Northwest Mexico. Pharmacogenomics J 2013;1-6.
    • (2013) Pharmacogenomics J , pp. 1-6
    • Sosa-Macias, M.1    Lazalde, B.P.2    Galaviz, C.3    Rangel, H.4    Salazar, J.5    Martínez, V.M.6
  • 21
    • 28444496691 scopus 로고    scopus 로고
    • Identification of CYP2D6 impaired functional alleles in Mexican Americans
    • Luo H, Gaedigk A, Aloumanis V, Wan Y. Identification of CYP2D6 impaired functional alleles in Mexican Americans. Eur J Clin Pharmacol 2005;61: 797-802.
    • (2005) Eur J Clin Pharmacol , vol.61 , pp. 797-802
    • Luo, H.1    Gaedigk, A.2    Aloumanis, V.3    Wan, Y.4
  • 22
    • 79957633461 scopus 로고    scopus 로고
    • Resequencing, haplotype construction and identification of novel variants of CYP2D6 identification of novel variants of CYP2D6 in Mexican Mestizos
    • Contreras A, Monge T, Alfaro L, Hernández S, Miranda H, Carrillo K, et al. Resequencing, haplotype construction and identification of novel variants of CYP2D6 identification of novel variants of CYP2D6 in Mexican Mestizos. Pharmacogenomics 2011;12: 745-56.
    • (2011) Pharmacogenomics , vol.12 , pp. 745-756
    • Contreras, A.1    Monge, T.2    Alfaro, L.3    Hernández, S.4    Miranda, H.5    Carrillo, K.6
  • 23
    • 33645787537 scopus 로고    scopus 로고
    • CYP2D6 genotype and phenotype in Amerindians of Tepehuano origin and Mestizos of Durango, Mexico
    • Sosa M, Elizondo G, Flores C, Flores J, Bradley F, Alanis R, et al. CYP2D6 genotype and phenotype in Amerindians of Tepehuano origin and Mestizos of Durango, Mexico. J Clin Pharmacol 2006;46: 527-36.
    • (2006) J Clin Pharmacol , vol.46 , pp. 527-536
    • Sosa, M.1    Elizondo, G.2    Flores, C.3    Flores, J.4    Bradley, F.5    Alanis, R.6
  • 24
    • 77953947158 scopus 로고    scopus 로고
    • Influence of CYP2D6 deletion, multiplication, -1555584C-G, 31 G-A and 2988 G-A gene polymorphism on dextromethorphan metabolism among Mexican Tepehuanos and Mestizos
    • Sosa M, Dorado P, Alanis R, Llerena A, Lares I. Influence of CYP2D6 deletion, multiplication, -1555584C-G, 31 G-A and 2988 G-A gene polymorphism on dextromethorphan metabolism among Mexican Tepehuanos and Mestizos. Pharmacology 2010;86: 30-6.
    • (2010) Pharmacology , vol.86 , pp. 30-36
    • Sosa, M.1    Dorado, P.2    Alanis, R.3    Llerena, A.4    Lares, I.5
  • 25
    • 27944474000 scopus 로고    scopus 로고
    • CYP2D6 genotype and phenotype determination in a Mexican Mestizo population
    • López, M, Guerrero J, Jung H, Alonso M. CYP2D6 genotype and phenotype determination in a Mexican Mestizo population. Eur J Clin Pharmacol 2005;61: 749-54.
    • (2005) Eur J Clin Pharmacol , vol.61 , pp. 749-754
    • López, M.1    Guerrero, J.2    Jung, H.3    Alonso, M.4
  • 26
    • 84896746009 scopus 로고    scopus 로고
    • Distribution of CYP2D6 and CYP2C19 polymorphisms associated with poor metabolizer phenotype in five Amerindian groups and Western Mestizos from Mexico
    • Salazar J, Torres LA, Martínez G, Rubí R, Sosa M, Muñoz JF, et al. Distribution of CYP2D6 and CYP2C19 polymorphisms associated with poor metabolizer phenotype in five Amerindian groups and Western Mestizos from Mexico. Genet Test Mol Biomarkers 2012;22.
    • (2012) Genet Test Mol Biomarkers , pp. 22
    • Salazar, J.1    Torres, L.A.2    Martínez, G.3    Rubí, R.4    Sosa, M.5    Muñoz, J.F.6
  • 27
    • 33745418092 scopus 로고    scopus 로고
    • Genetic polymorphism of cytochrome P450 2C19 in Mexicans Americans: A cross-ethnic comparative study
    • Luo H, Poland R, Lin K, Yvonne Y. Genetic polymorphism of cytochrome P450 2C19 in Mexicans Americans: a cross-ethnic comparative study. Clin Pharmacol Ther 2006;80: 33-40.
    • (2006) Clin Pharmacol Ther , vol.80 , pp. 33-40
    • Luo, H.1    Poland, R.2    Lin, K.3    Yvonne, Y.4
  • 28
    • 38749126770 scopus 로고    scopus 로고
    • A comparative study of CYP3A4 polymorphisms in Mexican Amerindian and Mestizo populations
    • Reyes O, Lares I, Sosa M, Vega L, Albores A, Elizondo G. A comparative study of CYP3A4 polymorphisms in Mexican Amerindian and Mestizo populations. Pharmacology 2008;81: 97-103.
    • (2008) Pharmacology , vol.81 , pp. 97-103
    • Reyes, O.1    Lares, I.2    Sosa, M.3    Vega, L.4    Albores, A.5    Elizondo, G.6
  • 30
    • 69249130069 scopus 로고    scopus 로고
    • Genotype and phenotype of NAT2 and the occurrence of adverse drug reactions in Mexican individuals to an isoniazidbased propylactic chemotherapy for tuberculosis
    • Díaz R, Cornejo J, Ramos M, Estrada J, Morales O, Reyes R, et al. Genotype and phenotype of NAT2 and the occurrence of adverse drug reactions in Mexican individuals to an isoniazidbased propylactic chemotherapy for tuberculosis. Mol Med Rep 2008;1: 875-9.
    • (2008) Mol Med Rep , vol.1 , pp. 875-879
    • Díaz, R.1    Cornejo, J.2    Ramos, M.3    Estrada, J.4    Morales, O.5    Reyes, R.6
  • 31
    • 84930474806 scopus 로고    scopus 로고
    • Arylamine N-acetyl transferase 2 genotypes in a Mexican population
    • Taja L, Agúndez JA, Miguez C, Chavez A, Dueñas A. Arylamine N-acetyl transferase 2 genotypes in a Mexican population. Genet Mol Res 2012;11: 1082-92.
    • (2012) Genet Mol Res , vol.11 , pp. 1082-1092
    • Taja, L.1    Agúndez, J.A.2    Miguez, C.3    Chavez, A.4    Dueñas, A.5
  • 32
    • 36348974483 scopus 로고    scopus 로고
    • Genotype frequencies of polymorphic GSTM1, GSTT1 and cytochrome P450 CYP1A1 in Mexicans
    • Montero R, Araujo A, Carranza P, Mejía C, Serrano L, Albores A, et al. Genotype frequencies of polymorphic GSTM1, GSTT1 and cytochrome P450 CYP1A1 in Mexicans. Hum Biol 2007;79: 299-312.
    • (2007) Hum Biol , vol.79 , pp. 299-312
    • Montero, R.1    Araujo, A.2    Carranza, P.3    Mejía, C.4    Serrano, L.5    Albores, A.6
  • 33
    • 0036738084 scopus 로고    scopus 로고
    • Cytochrome P450 2E1 and 3A activities do not differ between Mexicans and European Americans
    • Poland R, Lin K, Nuccio C, Wilkinson G. Cytochrome P450 2E1 and 3A activities do not differ between Mexicans and European Americans. Clin Pharmacol Ther 2002;72: 288-93.
    • (2002) Clin Pharmacol Ther , vol.72 , pp. 288-293
    • Poland, R.1    Lin, K.2    Nuccio, C.3    Wilkinson, G.4
  • 34
    • 84877993138 scopus 로고    scopus 로고
    • Interethnic differences in UGT1A4 genetic polymorphisms between Mexican Mestizo and Spanish populations
    • López M, Dorado P, Ortega A, Peñas E, Monroy N, Silva I, et al. Interethnic differences in UGT1A4 genetic polymorphisms between Mexican Mestizo and Spanish populations. Mol Biol Rep 2013;40: 3187-92.
    • (2013) Mol Biol Rep , vol.40 , pp. 3187-3192
    • López, M.1    Dorado, P.2    Ortega, A.3    Peñas, E.4    Monroy, N.5    Silva, I.6
  • 36
    • 0025285552 scopus 로고
    • A cocktail strategy to assess in vivo oxidative drug metabolism in humans
    • Breimer D, Schellens J. A cocktail strategy to assess in vivo oxidative drug metabolism in humans. Trends Pharmacol Sci 1990;11: 223-5.
    • (1990) Trends Pharmacol Sci , vol.11 , pp. 223-225
    • Breimer, D.1    Schellens, J.2
  • 37
    • 33846607427 scopus 로고    scopus 로고
    • Appropriate phenotyping procedures for drug metabolizing enzymes and transporters in human and their simultaneous use in the cocktail approach
    • Fuhr U, Jetter A, Kirchheiner J. Appropriate phenotyping procedures for drug metabolizing enzymes and transporters in human and their simultaneous use in the cocktail approach. Clin Pharmacol Ther 2007;81: 270-83.
    • (2007) Clin Pharmacol Ther , vol.81 , pp. 270-283
    • Fuhr, U.1    Jetter, A.2    Kirchheiner, J.3
  • 38
    • 0030712276 scopus 로고    scopus 로고
    • Pittsburgh cocktail" approach for assessment of selective regulation of drug-metabolizing enzymes
    • Frye R, Matzke G, Adedoyin A, Porter J, Branch A. "Pittsburgh cocktail" approach for assessment of selective regulation of drug-metabolizing enzymes. Clin Pharmacol Ther 1997;365-76.
    • (1997) Clin Pharmacol Ther , pp. 365-376
    • Frye, R.1    Matzke, G.2    Adedoyin, A.3    Porter, J.4    Branch, A.5
  • 40
    • 35448974964 scopus 로고    scopus 로고
    • Development of the "inje cocktail" for high-throughput evaluation of five human cytochrome P450 isoforms in vivo
    • Ryu J, Song I, Sunwoo Y, Shon J, Liu K, Cha I, et al. Development of the "Inje cocktail" for high-throughput evaluation of five human cytochrome P450 isoforms in vivo. Clin Pharmacol Ther 2007;82: 531-40.
    • (2007) Clin Pharmacol Ther , vol.82 , pp. 531-540
    • Ryu, J.1    Song, I.2    Sunwoo, Y.3    Shon, J.4    Liu, K.5    Cha, I.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.