Effects of maternal hypothyroidism on offspring hippocampus and memory

Thyroid

Volumn 24, Issue 3, 2014, Pages 576-584

  Willoughby, Karen A ^a,b   McAndrews, Mary Pat ^b,c   Rovet, Joanne F ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c TORONTO WESTERN HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

LEVOTHYROXINE; THYROID HORMONE; THYROTROPIN;

AMNESIA; ARTICLE; CHILD; CONTROLLED STUDY; FEMALE; HIPPOCAMPUS; HUMAN; HYPOTHYROIDISM; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MATERNAL DISEASE; MATERNAL HYPOTHYROIDISM; MEMORY; NUCLEAR MAGNETIC RESONANCE IMAGING; PREGNANCY; PRIORITY JOURNAL; PROGENY; SCHOOL CHILD; THIRD TRIMESTER PREGNANCY;

ADULT; CHILD; FEMALE; HIPPOCAMPUS; HUMANS; HYPOTHYROIDISM; MAGNETIC RESONANCE IMAGING; MALE; MEMORY; NEUROPSYCHOLOGICAL TESTS; ORGAN SIZE; PREGNANCY; PREGNANCY COMPLICATIONS; PRENATAL EXPOSURE DELAYED EFFECTS;

EID: 84896780430     PISSN: 10507256     EISSN: 15579077     Source Type: Journal    
DOI: 10.1089/thy.2013.0215     Document Type: Article

References (50)

1. Calvo R, Jauniaux E, Gulbis B, Asuncion M, Gervy C, Contempre B, Morreale de Escobar 2002 Fetal tissues are exposed to biologically relevant free thyroxine concentrations during early phases of development. J Clin Endocrinol Metab 87:1768-1777.
2. Kester MHA, Martinez de Mena R, Obregon MJ, Marinkovic D, Howatson A, Visser TJ, Hume R, Morreale de Escobar G 2004 Iodothyronine levels in the human developing brain: major regulatory roles of iodothryonine deiodinases in different areas. J Clin Endocrinol Metab 89:3117-3128.
3. Kilby MD, Gittoes N, McCabe C, Verhaeg J, Franklyn JA 2000 Expression of thyroid receptor isoforms in the human fetal central nervous system and the effects of intrauterine growth restriction. Clin Endocrinol 53:469-477.
4. Haddow JE, Palomaki GE, Allan WC, Williams JR, Knight GJ, Gagnon J, O'Heir CE, Mitchell ML, Hermos RJ, Waisbren SE, Faix JD, Klein RZ 1999 Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child. New Engl J Med 341:549-555.
5. Pop VJ, Brouwers EP, Vader HL, Vulsma V, van Baar AL, de Vijlder JJ 2003 Maternal hypothyroxinaemia during early pregnancy and subsequent child development: a 3-year follow-up study. Clin Endocrin 59:281-288.
6. Smit BJ, Kok JH, Vulsma T, Briët JM, Boer K, Wiersinga WM 2000 Neurologic development of the newborn and young child in relation to maternal thyroid function. Acta Paediatr 89:291-295.
7. Pop VJ, Kuijpens JL, van Baar AL, Verkerk G, van Son MM, de Vijlder JJ, Vulsma T, WiersingaWM, Drexhage HA, Vader HL 1999 Low maternal free thyroxine concentrations during early pregnancy are associated with impaired psychomotor development in infancy. Clin Endocrinol 50:149-155.
8. Henrichs J, Bongers-Schokking JJ, Schenk JJ, Ghassabian A, Schmidt HG, Visser TJ, Hoojkaas H, de Muinck Keizer-Schrama SMPF, Hofman A, Jaddow VVW, Visser W, Steegers EAP, Verhulst FC, Rijke YBD, Tiermeirer H 2010 Maternal thyroid function during early pregnancy and cognitive functioning in early childhood: the Generation R Study. J Clin Endocrinol Metab 95:4227-4234.
9. Mirabella G, Feig D, Astzalos E, Perlman K, Rovet JF 2000 The effect of abnormal intrauterine thyroid hormone economies on infant cognitive abilities. J Pediatr Endocrinol Metab 13:191-194.
10. Mirabella G, Westall CA, Asztalos E, Perlman K, Koren G, Rovet J 2005 Development of contrast sensitivity in infants with prenatal and neonatal thyroid hormone insufficiencies. Pediatr Res 57:902-907.
11. Madeira MD, Sousa N, Lima-Andrade MT, Calheiros F, Cadete-Leite A, Paula-Barbosa MM 1992 Selective vulnerability of the hippocampal pyramidal neurons to hypothyroidism in male and female rats. J Comp Neurol 322:501-518.
12. Rami A, Rabie A, Patel AJ 1986 Thyroid hormone and development of the rat hippocampus: cell acquisition in the dentate gyrus. Neuroscience 19:1207-1216.
13. Rami A, Patel AJ, Rabie A 1986 Thyroid hormone and development of the rat hippocampus: morphological alterations in granule and pyramidal cells. Neuroscience 19:1217-1226.
14. Hasegawa M, Kida I, Wada H 2010 A volumetric analysis of the brain and hippocampus of rats renered perinatal hypothyroid. Neurosci Lett 479:240-244.
15. Goodman JH, Gilbert ME 2007 Modest thyroid hormone insufficiency during development induces a cellular malformation in the corpus callosum: a model of cortical dysplasia. Endocrinology 149:2593-2597.
16. Gilbert ME, Sui L 2006 Dose-dependent reductions in spatial learning and synaptic function in the dentate gyrus of adult rats following developmental thyroid hormone insufficiency. Brain Res 1069:10-22.
17. Alzoubi KM, Gerges NZ, Aleisa AM, Alkadhi KM 2009 Levothyroxin restores hypothyroidism-induced impairment of hippocampus-dependent learning and memory: behavioral, electrophysioloical, and molecular studies. Hippocampus 19:66-78.
18. Opazo MC, Gianini A, Pacetti F, Azkcona G, Alarcon L, Lizana R, Noches V, Gonzalez PA, Porto M, Mora S, Rosenthal D, Eugenin E, Naranjo D, Bueno SM, Lalergis AM, Riedel CA 2008 Maternal hypothyroxinemia impairs spatial learning and synaptic nature and function in the offspring. Endocrinology 149:5097-5106.
19. Song SI, Daneman D, Rovet J. 2001 The influence of etiology and treatment factors on intellectual outcome in congenital hypothyroidism. J Devel Behav Pediatr 22:376-384.
20. Wheeler S, Willoughby K, McAndrews MP, Rovet J 2011 Hippocampal size and memory functioning in children and adolescents with congenital hypothryoidism. J Clin Endocrinol Metab 96:927, e1427-e1434.
21. Wheeler SM, McAndrews MP, Sheard ED, Rovet JF 2012 Visuospatial associative memory and hippocampal functioning in congenital hypothyroidism. J Int Neuropsychol Soc 18:49-56.
22. Arnold SE, Troójanowski JQ 1996 Human fetal hippocampal development: cytoarchitecture, myeloarchitecture, and neuronal morphologic features. J Comp Neurol 367:274-292.
23. Seress L, Ábrahám H, Tornóczky T, Kosztolányi GY 2001 Cell formation in the human hippocampal formation from mid-gestation to the late postnatal period. Neuroscience 105: 831-843.
24. Poppenk J, Moscovitch M 2011 A hippocampal marker of recollection memory ability among healthy young adults: Contributions of posterior and anterior segments. Neuron 72:931-937.
25. Martin VC, Schacter DL, Corballis MC, Addis DR 2011 A role for the hippocampus in encoding simulations of future events. Proc Nat Acad Sci USA 108:13858-13563.
26. Gogtay N, Nugent TF, Herman DH, Ordonez A, Greenstein D, Hayashi KM, Clasen L, Toga AW, Giedd JN, Rapoport JL, Thompson PM 2006 Dynamic mapping of normal human hippocampal development. Hippocampus 16:664-672.
27. Alexander EK, Marqsee E, Lawrence J, Jarolim P, Fischer GA, Larsen PR 2004 Timing and magnitude of increases in levothyroxine requirements during pregnancy in women with hypothyroidism. New Engl J Med 351:241-249.
28. Wechsler D 1999 Wechsler Abbreviated Scale of Intelligence. Psychological Corporation, New York, NY.
29. Wilkinson GS 1993 Wide Range Achievement Test - Revision 3. Jastak Association, Wilmington, DE.
30. Cohen MJ 1997 Children's Memory Scale: Manual. Psychological Corporation, San Antonio, TX.
31. Strauss E, Serman EMS, Spreen O 2006 A Compendium of Neuropsychological Tests. Third edition. Oxford University Press, New York, NY.
32. Lowther JL, Mayfield J 2004 Memory functioning in children with traumatic brain injuries: a TOMAL validity study. Arch Clin Neuropsychol 19:105-118.
33. Thaler NS, Barney SJ, Reynolds CR, Mayfield J, Allen DN 2011 Differential sensitivity of TOMAL subtests and index scores to pediatric traumatic brain injury. Appl Neuropsychol 18:168-178.
34. Southwick JS, Bigler ED, Froelich A, DuBray MB, Alexander AL, Lange N, Lainhart JE 2011 Memory functioning in children and adolescents with autism. Neuropsychology 25:702-710.
35. Gioia GA, Isquith PK, Guy PK, Kenworthy L 2000 Behavior Rating Inventory of Executive Function (BRIEF). Psychological Assessment Resources, Odessa, FL.
36. Sunderland A, Harris JE, Baddeley AD 1984 Assessing everyday memory after severe head injury. In: Harris JE, Morris PE (eds) Everyday Memory, Actions, and Absentmindedness. Academic Press, London, pp. 191-206.
37. Cornish IM 2000 Factor structure of the everyday memory questionnaire. Br J Psychol 91:427-438.
38. Isaacs EG, Lucas A, Chong WK, Wood SJ, Johnson CL, Marshall C, Vargha-Khadem F, Gadian DG 2000 Hippocampal volume and everyday memory in childrern of very low birth weight. Ped Res 47:713-720.
39. Weiss AP, Dewitt I, Goff D, Ditman T, Heckers S 2005 Anterior and posterior hippocampal volumes in schizophrenia. Schizophr Res 73:103-112.
40. Glinoer D, Spencer CA 2010 Serum TSH determinations in pregnancy: how, when and why? Nat Endo Rev 6:526-529.
41. Poppenk J, Evensmoen HR, Moscovitch M, Nadel L 2013 Long-axis specialization of the human hippocampus. Trends Cogn Sci 17:230-240.
42. Thompson DK, Wood SJ, Doyle LW, Warfield SK, Egan GF, Inder TE 2009 MR-determined hippocampal asymmetry in full-term and preterm neonates. Hippocampus 19:118-123.
43. Squire LR, Stark CE, Clark RE 2004 The medial temporal lobe. Annu Rev Neurosci 27:279-306.
44. Zimmerman ME, Pan JW, Hetherington HP, Katz MJ, Verghese J, Buschke H, Derby CA, Lipton RB 2008 Hippocampal neurochemistry, neuromorphometry, and verbal memory in nondemented older adults. Neurology 70:1594-1600.
45. Brickman AM, Stern Y, Small SA 2011 Hippocampal subregions differentially associate with standardized memory tests. Hippocampus 21:923-928.
46. Rovet JF, Lischinsky J, Clairman H, Skocic 2012 Maternal hypothyroidism affects offspring cortical cytoarchitecture. Thyroid 22:172.
47. Willoughby KA, McAndrews MP, Rovet J 2013 Effects of early thyroid hormone deficiency on children's autobiographical memory performance. J Intern Neuropsychol Soc 19:419-429.
48. Rovet J, Kopolovic I 2005 Increased incidence of behavior problems in offspring of women with thyroid disease in pregnancy. Thyroid 15:S-225 (Abstract no. P516).
49. De Groot L, Abalovich M, Alexander EK, Amino N, Barbour L, Cobin R, Eastman C, Lazarus J, Luton D, Mandel SJ, Mestman J, Rovet J, Sullivan S 2012 Management of thyroid dysfunction during pregnancy and postpartum: an Endocrine Society clinical practice guideline. J Clin Endo Metab 97:2543-2565.
50. Stagnaro-Green A, Abalovich M, Alexander A, Azizi F, Mestman J, Negro R, Nixon A, Pearce EN, Soldin O, Sullivan S, Wiersinga W; American Thyroid Association Taskforce on Thyroid Disease During Pregnancy and Postpartum 2012 Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and postpartum. Thyroid 21:1081-1126.