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Volumn 46, Issue 2, 2014, Pages 141-148

The changing face of GIST: Implications for pathologists

Author keywords

Gastrointestinal stromal tumour; Histopathology; Immunohistochemistry; KIT; Mutational analysis; PDGFRA; Risk stratification; SDHB

Indexed keywords

ARTICLE; CANCER STAGING; GASTROINTESTINAL STROMAL TUMOR; GASTROINTESTINAL TRACT; GENETIC PREDISPOSITION; GENETICS; HUMAN; MUTATION; PATHOLOGY; RISK ASSESSMENT;

EID: 84896777737     PISSN: 00313025     EISSN: 14653931     Source Type: Journal    
DOI: 10.1097/PAT.0000000000000047     Document Type: Article
Times cited : (10)

References (66)
  • 1
    • 84889681870 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumours
    • Fletcher C, Bridge J, Hogendoorn C, Mertens F, editors 4th ed. Lyon: IARC Press
    • Miettinen M, Corless C, Lasota J., et al Gastrointestinal stromal tumours. In: Fletcher C, Bridge J, Hogendoorn C, Mertens F, editors. WHO Classification of Tumours of Soft Tissue and Bone. 4th ed. Lyon: IARC Press, 2013.
    • (2013) WHO Classification of Tumours of Soft Tissue and Bone
    • Miettinen, M.1    Corless, C.2    Lasota, J.3
  • 2
    • 33845940073 scopus 로고    scopus 로고
    • Minute gastric sclerosing stromal tumors (GIST tumorlets) are common in adults and frequently show c-KIT mutations
    • Agaimy A, Wunsch P, Hofstaedter F., et al Minute gastric sclerosing stromal tumors (GIST tumorlets) are common in adults and frequently show c-KIT mutations. Am J Surg Pathol 2007; 31: 113-20.
    • (2007) Am J Surg Pathol , vol.31 , pp. 113-120
    • Agaimy, A.1    Wunsch, P.2    Hofstaedter, F.3
  • 3
    • 33751225088 scopus 로고    scopus 로고
    • High incidence of microscopic gastrointestinal stromal tumors in the stomach
    • Kawanowa K, Sakuma Y, Sakurai S., et al High incidence of microscopic gastrointestinal stromal tumors in the stomach. Hum Pathol 2006; 37: 1527-35.
    • (2006) Hum Pathol , vol.37 , pp. 1527-1535
    • Kawanowa, K.1    Sakuma, Y.2    Sakurai, S.3
  • 4
    • 0036301722 scopus 로고    scopus 로고
    • Diagnosis of gastrointestinal stromal tumors: A consensus approach
    • Fletcher C, Berman J, Corless C., et al Diagnosis of gastrointestinal stromal tumors: A consensus approach. Hum Pathol 2002; 33: 459-65.
    • (2002) Hum Pathol , vol.33 , pp. 459-465
    • Fletcher, C.1    Berman, J.2    Corless, C.3
  • 5
    • 33750618188 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors: Pathology and prognosis at different sites
    • Miettinen M, Lasota J. Gastrointestinal stromal tumors: pathology and prognosis at different sites. Semin Diagn Pathol 2006; 23: 70-83.
    • (2006) Semin Diagn Pathol , vol.23 , pp. 70-83
    • Miettinen, M.1    Lasota, J.2
  • 6
    • 71449088757 scopus 로고    scopus 로고
    • Development and validation of a prognostic nomogram for recurrence-free survival after complete surgical resection of localised primary gastrointestinal stromal tumour: A retrospective analysis
    • Gold J, Gonen M, Gutierrez A., et al Development and validation of a prognostic nomogram for recurrence-free survival after complete surgical resection of localised primary gastrointestinal stromal tumour: a retrospective analysis. Lancet Oncol 2009; 10: 1045-52.
    • (2009) Lancet Oncol , vol.10 , pp. 1045-1052
    • Gold, J.1    Gonen, M.2    Gutierrez, A.3
  • 7
    • 80054971913 scopus 로고    scopus 로고
    • Natural history of imatinib-naive GISTs: A retrospective analysis of 929 cases with long-term follow-up and development of a survival nomogram based on mitotic index and size as continuous variables
    • Rossi S, Miceli R, Messerini L., et al Natural history of imatinib-naive GISTs: a retrospective analysis of 929 cases with long-term follow-up and development of a survival nomogram based on mitotic index and size as continuous variables. Am J Surg Pathol 2011; 35: 1646-56.
    • (2011) Am J Surg Pathol , vol.35 , pp. 1646-1656
    • Rossi, S.1    Miceli, R.2    Messerini, L.3
  • 8
    • 66849135214 scopus 로고    scopus 로고
    • The triad of paragangliomas, gastric stromal tumours and pulmonary chondromas (Carney triad), and the dyad of paragangliomas and gastric stromal sarcomas (Carney-stratakis syndrome): Molecular genetics and clinical implications
    • Stratakis C, Carney J. The triad of paragangliomas, gastric stromal tumours and pulmonary chondromas (Carney triad), and the dyad of paragangliomas and gastric stromal sarcomas (Carney-Stratakis syndrome): molecular genetics and clinical implications. J Intern Med 2009; 266: 43-52.
    • (2009) J Intern Med , vol.266 , pp. 43-52
    • Stratakis, C.1    Carney, J.2
  • 9
    • 37349074531 scopus 로고    scopus 로고
    • Clinical and molecular genetics of patients with the carney-stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHD
    • Pasini B, McWhinney S, Bei T., et al Clinical and molecular genetics of patients with the Carney-Stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHD. Eur J Hum Genet 2008; 16: 79-88.
    • (2008) Eur J Hum Genet , vol.16 , pp. 79-88
    • Pasini, B.1    McWhinney, S.2    Bei, T.3
  • 10
    • 84877850694 scopus 로고    scopus 로고
    • SKP2 high expression, KIT exon 11 deletions,;1; and gastrointestinal bleeding as predictors of poor prognosis in primary gastrointestinal stromal tumors
    • Lv A, Li Z, Tian X., et al SKP2 high expression, KIT exon 11 deletions,;1; and gastrointestinal bleeding as predictors of poor prognosis in primary gastrointestinal stromal tumors. PLoS ONE 2013; 8: e62951.
    • (2013) PLoS ONE , vol.8
    • Lv, A.1    Li, Z.2    Tian, X.3
  • 11
    • 84857502045 scopus 로고    scopus 로고
    • Risk of recurrence of gastrointestinal stromal tumour after surgery: An analysis of pooled population-based cohorts
    • Joensuu H, Vehtari J, Nishida T., et al Risk of recurrence of gastrointestinal stromal tumour after surgery: an analysis of pooled population-based cohorts. Lancet Oncol 2012; 13: 265-74.
    • (2012) Lancet Oncol , vol.13 , pp. 265-274
    • Joensuu, H.1    Vehtari, J.2    Nishida, T.3
  • 12
    • 70249089412 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors presenting as omental masses - A clinicopathologic analysis of 95 cases
    • Miettinen M, Sobin L, Lasota J. Gastrointestinal stromal tumors presenting as omental masses - A clinicopathologic analysis of 95 cases. Am J Surg Pathol 2009; 33: 1267-75.
    • (2009) Am J Surg Pathol , vol.33 , pp. 1267-1275
    • Miettinen, M.1    Sobin, L.2    Lasota, J.3
  • 13
    • 77953079312 scopus 로고    scopus 로고
    • Primary extragastrointestinal stromal tumor of the pleura: Report of a unique case with genetic confirmation
    • Long K, Butrynski J, Blank S., et al Primary extragastrointestinal stromal tumor of the pleura: report of a unique case with genetic confirmation. Am J Surg Pathol 2010; 34: 907-12.
    • (2010) Am J Surg Pathol , vol.34 , pp. 907-912
    • Long, K.1    Butrynski, J.2    Blank, S.3
  • 14
    • 21244460383 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors metastatic to the ovary: A report of five cases
    • Irving J, Lerwill M, Young R. Gastrointestinal stromal tumors metastatic to the ovary: A report of five cases. Am J Surg Pathol 2005; 29: 920-6.
    • (2005) Am J Surg Pathol , vol.29 , pp. 920-926
    • Irving, J.1    Lerwill, M.2    Young, R.3
  • 15
    • 13144273797 scopus 로고    scopus 로고
    • Cerebral relapse of metastatic gastrointestinal stromal tumor during treatment with imatinib mesylate: Case report
    • Hughes B, Yip D, Goldstein D., et al Cerebral relapse of metastatic gastrointestinal stromal tumor during treatment with imatinib mesylate: case report. BMC Cancer 2004; 4: 74.
    • (2004) BMC Cancer , vol.4 , pp. 74
    • Hughes, B.1    Yip, D.2    Goldstein, D.3
  • 16
    • 84863828994 scopus 로고    scopus 로고
    • Imaging features of bone metastases in patients with gastrointestinal stromal tumors
    • Jati A, Tatli S, Morgan J., et al Imaging features of bone metastases in patients with gastrointestinal stromal tumors. Diagn Interv Radiol 2012; 18: 391-6.
    • (2012) Diagn Interv Radiol , vol.18 , pp. 391-396
    • Jati, A.1    Tatli, S.2    Morgan, J.3
  • 17
    • 13444270334 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors: The incidence, the prevalence, clinical course and prognostication in the preimatinib mesylate era: A population-based study in Western Sweden
    • Nilsson B, Bumming P, Meis-Kindblom J, et al Gastrointestinal stromal tumors: the incidence, the prevalence, clinical course and prognostication in the preimatinib mesylate era: A population-based study in western Sweden. Cancer 2005; 103: 821-9.
    • (2005) Cancer , vol.103 , pp. 821-829
    • Nilsson, B.1    Bumming, P.2    Meis-Kindblom, J.3
  • 18
    • 0017736213 scopus 로고
    • The triad of gastric leiomyosarcoma, functioning extra-adrenal paraganglioma and pulmonary chondroma
    • Carney J, Sheps S, Go V., Gordon H. The triad of gastric leiomyosarcoma, functioning extra-adrenal paraganglioma and pulmonary chondroma. N Engl J Med 1977; 296: 1517-8.
    • (1977) N Engl J Med , vol.296 , pp. 1517-1518
    • Carney, J.1    Sheps, S.2    Go, V.3    Gordon, H.4
  • 19
    • 0036499042 scopus 로고    scopus 로고
    • Familial paraganglioma and gastric stromal sarcoma: A new syndrome distinct from carney triad
    • Carney J, Stratakis C. Familial paraganglioma and gastric stromal sarcoma: a new syndrome distinct from Carney triad. Am J Med Genet 2002; 108: 132-9.
    • (2002) Am J Med Genet , vol.108 , pp. 132-139
    • Carney, J.1    Stratakis, C.2
  • 20
    • 34548386693 scopus 로고    scopus 로고
    • Familial gastrointestinal stromal tumors and germ-line mutations
    • McWhinney S, Pasini B, Stratakis C. Familial gastrointestinal stromal tumors and germ-line mutations. N Engl J Med 2007; 357: 1054-6.
    • (2007) N Engl J Med , vol.357 , pp. 1054-1056
    • McWhinney, S.1    Pasini, B.2    Stratakis, C.3
  • 21
    • 84872864140 scopus 로고    scopus 로고
    • Immunohistochemical loss of succinate dehydrogenase subunit A (SDHA) in gastrointestinal stromal tumors (GISTs) signals SDHA germline mutation
    • Miettinen M, Killian J, Wang Z., et al Immunohistochemical loss of succinate dehydrogenase subunit A (SDHA) in gastrointestinal stromal tumors (GISTs) signals SDHA germline mutation. Am J Surg Pathol 2013; 37: 234-40.
    • (2013) Am J Surg Pathol , vol.37 , pp. 234-240
    • Miettinen, M.1    Killian, J.2    Wang, Z.3
  • 22
    • 84872850446 scopus 로고    scopus 로고
    • Loss of SDHA expression identifies SHDA mutations in succinate dehydrogenase-deficient gastrointestinal stromal tumors
    • Dwight T, Benn D, Clarkson A., et al Loss of SDHA expression identifies SHDA mutations in succinate dehydrogenase-deficient gastrointestinal stromal tumors. Am J Surg Pathol 2013; 37: 226-33.
    • (2013) Am J Surg Pathol , vol.37 , pp. 226-233
    • Dwight, T.1    Benn, D.2    Clarkson, A.3
  • 23
    • 84878654100 scopus 로고    scopus 로고
    • Inherited gastrointestinal stromal tumor syndromes: Mutations, clinical features, and therapeutic implications
    • Postow M, Robson M. Inherited gastrointestinal stromal tumor syndromes: mutations, clinical features, and therapeutic implications. Clin Sarcoma Res 2012; 2: 16.
    • (2012) Clin Sarcoma Res , vol.2 , pp. 16
    • Postow, M.1    Robson, M.2
  • 24
    • 34547781842 scopus 로고    scopus 로고
    • Genetics of carney triad: Recurrent losses at chromosome 1 but lack of germline mutations in genes associated with paragangliomas and gastrointestinal stromal tumors
    • Matyakhina L, Bei T, McWhinney S., et al Genetics of Carney triad: Recurrent losses at chromosome 1 but lack of germline mutations in genes associated with paragangliomas and gastrointestinal stromal tumors. J Clin Endocrinol Metab 2007; 92: 2938-43.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 2938-2943
    • Matyakhina, L.1    Bei, T.2    McWhinney, S.3
  • 25
    • 80055020285 scopus 로고    scopus 로고
    • Succinate dehydrogenase-deficient GISTs: A clinicopathologic, immunohistochemical, and molecular genetic study of 66 gastric GISTs with predilection to young age
    • Miettinen M, Wang Z, Sarlomo-Rikala M, et al Succinate dehydrogenase-deficient GISTs: A clinicopathologic, immunohistochemical, and molecular genetic study of 66 gastric GISTs with predilection to young age. Am J Surg Pathol 2011; 35: 1712-21.
    • (2011) Am J Surg Pathol , vol.35 , pp. 1712-1721
    • Miettinen, M.1    Wang, Z.2    Sarlomo-Rikala, M.3
  • 26
    • 84873413449 scopus 로고    scopus 로고
    • Loss of expression of SDHA predicts SHDA mutations in gastrointestinal stromal tumors
    • Wagner A, Remillard S, Zhang Y., et al Loss of expression of SDHA predicts SHDA mutations in gastrointestinal stromal tumors. Mod Pathol 2013; 26: 289-94.
    • (2013) Mod Pathol , vol.26 , pp. 289-294
    • Wagner, A.1    Remillard, S.2    Zhang, Y.3
  • 27
    • 78650866382 scopus 로고    scopus 로고
    • SDHB immunohistochemistry: A useful took in the diagnosis of carney-stratakis and carney triad gastrointestinal stromal tumors
    • Gaal J, Stratakis C, Carney J., et al SDHB immunohistochemistry: A useful took in the diagnosis of Carney-Stratakis and Carney triad gastrointestinal stromal tumors. Mod Pathol 2011; 24: 147-51.
    • (2011) Mod Pathol , vol.24 , pp. 147-151
    • Gaal, J.1    Stratakis, C.2    Carney, J.3
  • 28
    • 0347361543 scopus 로고    scopus 로고
    • PDGFRA germline mutation in a family with multiple cases of gastrointestinal stromal tumor
    • Chompret A, Kannengiesser C, Barrois M., et al PDGFRA germline mutation in a family with multiple cases of gastrointestinal stromal tumor. Gastroenterology 2004; 126: 318-21.
    • (2004) Gastroenterology , vol.126 , pp. 318-321
    • Chompret, A.1    Kannengiesser, C.2    Barrois, M.3
  • 29
    • 84880178200 scopus 로고    scopus 로고
    • A novel germline mutation (p. L576P) in a family presenting with juvenile onset of multiple gastrointestinal stromal tumors, skin hyperpigmentations, and esophageal stenosis
    • Neuhann T, Mansmann V, Merkelbach-Bruse S, et al A novel germline mutation (p. L576P) in a family presenting with juvenile onset of multiple gastrointestinal stromal tumors, skin hyperpigmentations, and esophageal stenosis. Am J Surg Pathol 2013; 37: 898-905.
    • (2013) Am J Surg Pathol , vol.37 , pp. 898-905
    • Neuhann, T.1    Mansmann, V.2    Merkelbach-Bruse, S.3
  • 30
    • 12944291461 scopus 로고    scopus 로고
    • Novel c-KIT germline mutation in a family with gastrointestinal stromal tumors and cutaneous hyperpigmentation
    • Carballo M, Roig I, Aguilar F., et al Novel c-KIT germline mutation in a family with gastrointestinal stromal tumors and cutaneous hyperpigmentation. Am J Med Genet A 2005; 132: 361-4.
    • (2005) Am J Med Genet A , vol.132 , pp. 361-364
    • Carballo, M.1    Roig, I.2    Aguilar, F.3
  • 31
    • 0035174752 scopus 로고    scopus 로고
    • Familial gastrointestinal stromal tumor with hyperpigmentation: Association with a germline mutation of the c-kit gene
    • Maeyama H, Hidaka E, Ota H., et al Familial gastrointestinal stromal tumor with hyperpigmentation: association with a germline mutation of the c-kit gene. Gastroenterology 2001; 120: 210-5.
    • (2001) Gastroenterology , vol.120 , pp. 210-215
    • Maeyama, H.1    Hidaka, E.2    Ota, H.3
  • 32
    • 33749459756 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors: Review on morphology, molecular pathology, prognosis and differential diagnosis
    • Miettinen M, Lasota J. Gastrointestinal stromal tumors: Review on morphology, molecular pathology, prognosis and differential diagnosis. Arch Pathol Lab Med 2006; 130: 1466-78.
    • (2006) Arch Pathol Lab Med , vol.130 , pp. 1466-1478
    • Miettinen, M.1    Lasota, J.2
  • 33
    • 51649112019 scopus 로고    scopus 로고
    • Therapeutic consequences from molecular biology for gastrointestinal stromal tumor patients affected by neurofibromatosis type I
    • Mussi C, Schildhaus H, Gronchi A., et al Therapeutic consequences from molecular biology for gastrointestinal stromal tumor patients affected by neurofibromatosis type I. Clin Cancer Res 2008; 14: 4550-5.
    • (2008) Clin Cancer Res , vol.14 , pp. 4550-4555
    • Mussi, C.1    Schildhaus, H.2    Gronchi, A.3
  • 34
    • 79959921466 scopus 로고    scopus 로고
    • Succinate dehydrogenase subunit B (SDHB) is expressed in neurofibromatosis 1-associated gastrointestinal stromal tumors (GISTs): Implications for the SDHB expression based classification of GISTs
    • Wang J, Lasota J, Miettinen M. Succinate dehydrogenase subunit B (SDHB) is expressed in neurofibromatosis 1-associated gastrointestinal stromal tumors (GISTs): Implications for the SDHB expression based classification of GISTs. J Cancer 2011; 16: 90-3.
    • (2011) J Cancer , vol.16 , pp. 90-93
    • Wang, J.1    Lasota, J.2    Miettinen, M.3
  • 35
    • 33644781795 scopus 로고    scopus 로고
    • Molecular pathogenesis of multiple gastrointestinal stromal tumors in NF1 patients
    • Maertens O, Prenen H, Debiec-Rychter M, et al Molecular pathogenesis of multiple gastrointestinal stromal tumors in NF1 patients. Hum Mol Genet 2006; 15: 1015-23.
    • (2006) Hum Mol Genet , vol.15 , pp. 1015-1023
    • Maertens, O.1    Prenen, H.2    Debiec-Rychter, M.3
  • 36
    • 76649098899 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumor and other primary metachronous or synchronous neoplasms as a suspicion criterion for syndromic setting
    • Ponti G, Luppi G, Martorana D., et al Gastrointestinal stromal tumor and other primary metachronous or synchronous neoplasms as a suspicion criterion for syndromic setting. Oncol Reports 2012; 23: 437-44.
    • (2012) Oncol Reports , vol.23 , pp. 437-444
    • Ponti, G.1    Luppi, G.2    Martorana, D.3
  • 37
    • 38749153233 scopus 로고    scopus 로고
    • A nonrandom association between gastrointestinal stromal tumors and myeloid leukaemia
    • Miettinen M, Kraszewska E, Sobin L., Lasota J. A nonrandom association between gastrointestinal stromal tumors and myeloid leukaemia. Cancer 2008; 112: 645-9.
    • (2008) Cancer , vol.112 , pp. 645-649
    • Miettinen, M.1    Kraszewska, E.2    Sobin, L.3    Lasota, J.4
  • 38
    • 81555207574 scopus 로고    scopus 로고
    • Small-intestinal rhabdoid gastrointestinal stromal tumor (GIST): Mutation analysis and clinical implications of a rare morphological variant
    • Hanson J, Trent J, Yang D., Cooper K. Small-intestinal rhabdoid gastrointestinal stromal tumor (GIST): Mutation analysis and clinical implications of a rare morphological variant. Int J Surg Pathol 2011; 19: 653-7.
    • (2011) Int J Surg Pathol , vol.19 , pp. 653-657
    • Hanson, J.1    Trent, J.2    Yang, D.3    Cooper, K.4
  • 39
    • 84873987649 scopus 로고    scopus 로고
    • Dedifferentiation in gastrointestinal stromal tumor to an anaplastic KIT-negative phenotype: A diagnostic pitfall: Morphologic and molecular characterization of 8 cases occurring either de novo or after imatinib therapy
    • Antonescu C, Romeo S, Zhang L., et al Dedifferentiation in gastrointestinal stromal tumor to an anaplastic KIT-negative phenotype: a diagnostic pitfall: morphologic and molecular characterization of 8 cases occurring either de novo or after imatinib therapy. Am J Surg Pathol 2013; 37: 385-92.
    • (2013) Am J Surg Pathol , vol.37 , pp. 385-392
    • Antonescu, C.1    Romeo, S.2    Zhang, L.3
  • 40
    • 22144464484 scopus 로고    scopus 로고
    • Changing phenotype of gastrointestinal stromal tumours under imatinib mesylate treatment: A potential diagnostic pitfall
    • Pauwels P, Debiec-Rychter M, Stul M., et al Changing phenotype of gastrointestinal stromal tumours under imatinib mesylate treatment: A potential diagnostic pitfall. Histopathology 2005; 47: 41-7.
    • (2005) Histopathology , vol.47 , pp. 41-47
    • Pauwels, P.1    Debiec-Rychter, M.2    Stul, M.3
  • 41
    • 84868127746 scopus 로고    scopus 로고
    • The lack of CD34 expression in gastrointestinal stromal tumors is related to cystic degeneration following imatinib use
    • Koh Y, Lee H, Ohn D., et al The lack of CD34 expression in gastrointestinal stromal tumors is related to cystic degeneration following imatinib use. Jpn J Clin Oncol 2012; 42: 1020-7.
    • (2012) Jpn J Clin Oncol , vol.42 , pp. 1020-1027
    • Koh, Y.1    Lee, H.2    Ohn, D.3
  • 42
    • 53749088452 scopus 로고    scopus 로고
    • Decrease of CD117 expression as possible prognostic marker for recurrence in the resected specimen after imatinib treatment in patients with initially unresectable gastrointestinal stromal tumors: A clinicopathological analysis
    • Mearadji A, den Bakker M, van Geel A, et al Decrease of CD117 expression as possible prognostic marker for recurrence in the resected specimen after imatinib treatment in patients with initially unresectable gastrointestinal stromal tumors: A clinicopathological analysis. Anticancer Drugs 2008; 19: 607-12.
    • (2008) Anticancer Drugs , vol.19 , pp. 607-612
    • Mearadji, A.1    Den Bakker, M.2    Van Geel, A.3
  • 43
    • 33644667084 scopus 로고    scopus 로고
    • Surgical treatment of patients with initially inoperable and/or metastatic gastrointestinal stromal tumors (GIST) during therapy with imatinib mesylate
    • Rutkowski P, Nowecki Z, Nyckowski P., et al Surgical treatment of patients with initially inoperable and/or metastatic gastrointestinal stromal tumors (GIST) during therapy with imatinib mesylate. J Surg Oncol 2006; 93: 304-11.
    • (2006) J Surg Oncol , vol.93 , pp. 304-311
    • Rutkowski, P.1    Nowecki, Z.2    Nyckowski, P.3
  • 44
    • 60249088620 scopus 로고    scopus 로고
    • Rhabdomyosarcomatous differentiation in gastrointestinal stromal tumors after tyrosine kinase inhibitor therapy: A novel form of tumor progression
    • Liegl B, Hornick J, Antonescu C., et al Rhabdomyosarcomatous differentiation in gastrointestinal stromal tumors after tyrosine kinase inhibitor therapy: A novel form of tumor progression. Am J Surg Pathol 2009; 33: 218-26.
    • (2009) Am J Surg Pathol , vol.33 , pp. 218-226
    • Liegl, B.1    Hornick, J.2    Antonescu, C.3
  • 45
    • 33846277973 scopus 로고    scopus 로고
    • Pathologic and molecular heterogeneity in imatinib-stable or imatinib-responsive gastrointestinal stromal tumors
    • Agaram N, Besmer P, Wong G., et al Pathologic and molecular heterogeneity in imatinib-stable or imatinib-responsive gastrointestinal stromal tumors. Clin Cancer Res 2007; 13: 170-81.
    • (2007) Clin Cancer Res , vol.13 , pp. 170-181
    • Agaram, N.1    Besmer, P.2    Wong, G.3
  • 46
    • 3042594995 scopus 로고    scopus 로고
    • The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status
    • West R, Corless C, Chen X., et al The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status. Am J Pathol 2004; 165: 107-13.
    • (2004) Am J Pathol , vol.165 , pp. 107-113
    • West, R.1    Corless, C.2    Chen, X.3
  • 47
    • 62849083680 scopus 로고    scopus 로고
    • Monoclonal antibody DOG1.1 shows higher sensitivity than KIT in the diagnosis of gastrointestinal stromal tumors, including unusual subtypes
    • Liegl B, Hornick J, Corless C., Fletcher C. Monoclonal antibody DOG1.1 shows higher sensitivity than KIT in the diagnosis of gastrointestinal stromal tumors, including unusual subtypes. Am J Surg Pathol 2009; 33: 437-46.
    • (2009) Am J Surg Pathol , vol.33 , pp. 437-446
    • Liegl, B.1    Hornick, J.2    Corless, C.3    Fletcher, C.4
  • 48
    • 44249095855 scopus 로고    scopus 로고
    • Gastrointestinal kaposi's sarcoma: CD117 expression and the potential for misdiagnosis as gastrointestinal stromal tumour
    • Parfitt J, Rodriguez-Justo M, Feakings R., Novelli M. Gastrointestinal Kaposi's sarcoma: CD117 expression and the potential for misdiagnosis as gastrointestinal stromal tumour. Histopathology 2008; 52: 816-23.
    • (2008) Histopathology , vol.52 , pp. 816-823
    • Parfitt, J.1    Rodriguez-Justo, M.2    Feakings, R.3    Novelli, M.4
  • 49
    • 84887884224 scopus 로고    scopus 로고
    • Metastatic gastrointestinal stromal tumour of the ileum with dual primary c-KIT missence (sic) mutations
    • Malik L, Hemmings C, Beshay V., et al Metastatic gastrointestinal stromal tumour of the ileum with dual primary c-KIT missence (sic) mutations. Pathology 2013; 45: 604-6.
    • (2013) Pathology , vol.45 , pp. 604-606
    • Malik, L.1    Hemmings, C.2    Beshay, V.3
  • 50
    • 84865686981 scopus 로고    scopus 로고
    • Adjuvant therapy of gastrointestinal stormal tumors (GIST)
    • Casali P, Fumagalli E, Gronchi A. Adjuvant therapy of gastrointestinal stormal tumors (GIST). Curr Treat Options Oncol 2013; 13: 277-84.
    • (2013) Curr Treat Options Oncol , vol.13 , pp. 277-284
    • Casali, P.1    Fumagalli, E.2    Gronchi, A.3
  • 51
    • 77949898532 scopus 로고    scopus 로고
    • (MetaGIST)Comparison of two doses of imatinib for the treatment of unresectable or metastatic gastrointestinal stromal tumors: A meta-analysis of 1,640 patients
    • Gastrointestinal Stromal Tumor Meta-Analysis Group
    • Gastrointestinal Stromal Tumor Meta-Analysis Group (MetaGIST)Comparison of two doses of imatinib for the treatment of unresectable or metastatic gastrointestinal stromal tumors: A meta-analysis of 1,640 patients. J Clin Oncol 2010; 28: 1247-53.
    • (2010) J Clin Oncol , vol.28 , pp. 1247-1253
  • 52
    • 84883473901 scopus 로고    scopus 로고
    • Detection of mutant free circulating tumor DNA in the plasma of patients with gastrointestinal stromal tumor harbouring activating mutations of CKIT or PDGFRA
    • Maier J, Lange T, Kerle I., et al Detection of mutant free circulating tumor DNA in the plasma of patients with gastrointestinal stromal tumor harbouring activating mutations of CKIT or PDGFRA. Clin Cancer Res 2013; 19: 4854-67.
    • (2013) Clin Cancer Res , vol.19 , pp. 4854-4867
    • Maier, J.1    Lange, T.2    Kerle, I.3
  • 53
    • 46149111291 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF) 1 and 2 help to predict disease outcome in GIST patients
    • Braconi C, Bracci R, Bearzi I., et al Insulin-like growth factor (IGF) 1 and 2 help to predict disease outcome in GIST patients. Ann Oncol 2008; 19: 1293-8.
    • (2008) Ann Oncol , vol.19 , pp. 1293-1298
    • Braconi, C.1    Bracci, R.2    Bearzi, I.3
  • 54
    • 67649391047 scopus 로고    scopus 로고
    • Clinical and molecular characteristics of gastrointestinal stromal tumor in the pediatric and young adult population
    • Rink L, Godwin A. Clinical and molecular characteristics of gastrointestinal stromal tumor in the pediatric and young adult population. Curr Oncol Rep 2009; 11: 314-21.
    • (2009) Curr Oncol Rep , vol.11 , pp. 314-321
    • Rink, L.1    Godwin, A.2
  • 55
    • 84865713085 scopus 로고    scopus 로고
    • Succinate dehydrogenase-deficient GISTs are characterized by IGF1R overexpression
    • Chou A, Chen J, Clarkson A., et al Succinate dehydrogenase-deficient GISTs are characterized by IGF1R overexpression. Mod Pathol 2012; 25: 1307-13.
    • (2012) Mod Pathol , vol.25 , pp. 1307-1313
    • Chou, A.1    Chen, J.2    Clarkson, A.3
  • 56
    • 84871618647 scopus 로고    scopus 로고
    • Expression of the receptor for type I insulinlike growth factor (IGF1R) in gastrointestinal stromal tumors: An immunohistochemical study of 1078 cases with diagnostic and therapeutic implications
    • Lasota J, Wang Z, Kim S., et al Expression of the receptor for type I insulinlike growth factor (IGF1R) in gastrointestinal stromal tumors: An immunohistochemical study of 1078 cases with diagnostic and therapeutic implications. Am J Surg Pathol 2013; 37: 114-9.
    • (2013) Am J Surg Pathol , vol.37 , pp. 114-119
    • Lasota, J.1    Wang, Z.2    Kim, S.3
  • 57
    • 46149104384 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumors
    • Tarn C, Rink L, Merkel E., et al Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumors. Proc Natl Acad Sci USA 2008; 105: 8387-92.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 8387-8392
    • Tarn, C.1    Rink, L.2    Merkel, E.3
  • 58
    • 50249152932 scopus 로고    scopus 로고
    • Novel V600E BRAF mutations in imatinib-naïve and imatinib-resistant gastrointestinal stromal tumours
    • Agaram N, Wong G, Guo T., et al Novel V600E BRAF mutations in imatinib-naïve and imatinib-resistant gastrointestinal stromal tumours. Genes Chromosomes Cancer 2008; 47: 853-9.
    • (2008) Genes Chromosomes Cancer , vol.47 , pp. 853-859
    • Agaram, N.1    Wong, G.2    Guo, T.3
  • 59
    • 84867675380 scopus 로고    scopus 로고
    • Cancer staging handbook. 7th ed
    • Chapter 16, Gastrointestinal stromal tumor
    • Edge S, Byrd D, Compton C., et al Cancer Staging Handbook. 7th ed. New York: Springer, 2010. Chapter 16, Gastrointestinal stromal tumor.
    • (2010) New York: Springer
    • Edge, S.1    Byrd, D.2    Compton, C.3
  • 60
    • 50649085726 scopus 로고    scopus 로고
    • Risk stratification of patients diagnosed with gastrointestinal stromal tumor
    • Joensuu H. Risk stratification of patients diagnosed with gastrointestinal stromal tumor. Hum Pathol 2008; 39: 1411-9.
    • (2008) Hum Pathol , vol.39 , pp. 1411-1419
    • Joensuu, H.1
  • 61
    • 35348871015 scopus 로고    scopus 로고
    • An enhanced risk-group stratification system for more practical prognostication of clinically Malignant gastrointestinal stromal tumors
    • Takahashi T, Nakajima K, Nishitani A., et al An enhanced risk-group stratification system for more practical prognostication of clinically malignant gastrointestinal stromal tumors. Int J Clin Oncol 2007; 12: 369-74.
    • (2007) Int J Clin Oncol , vol.12 , pp. 369-374
    • Takahashi, T.1    Nakajima, K.2    Nishitani, A.3
  • 62
    • 80052963619 scopus 로고    scopus 로고
    • Validation of the joensuu risk criteria for primary resectable gastrointestinal stromal tumour - The impact of tumour rupture on patient outcomes
    • Rutkowski P, Bylina E, Wozniak A., et al Validation of the Joensuu risk criteria for primary resectable gastrointestinal stromal tumour - The impact of tumour rupture on patient outcomes. Eur J Surg Oncol 2011; 37: 890-6.
    • (2011) Eur J Surg Oncol , vol.37 , pp. 890-896
    • Rutkowski, P.1    Bylina, E.2    Wozniak, A.3
  • 63
    • 33745469852 scopus 로고    scopus 로고
    • Altered expression of cell cycle regulatory proteins in gastrointestinal stromal tumors: Markers with potential prognostic implications
    • Sabah M, Cummins R, Leader M., Kay E. Altered expression of cell cycle regulatory proteins in gastrointestinal stromal tumors: Markers with potential prognostic implications. Hum Pathol 2006; 37: 648-55.
    • (2006) Hum Pathol , vol.37 , pp. 648-655
    • Sabah, M.1    Cummins, R.2    Leader, M.3    Kay, E.4
  • 64
    • 33645826059 scopus 로고    scopus 로고
    • Expresion of bcl-2 in gastrointestinal stromal tumors: Correlation with progression-free survival in 81 patients treated with imatinib mesylate
    • Steinert D, Oyarzo M, Wang X., et al Expresion of Bcl-2 in gastrointestinal stromal tumors: correlation with progression-free survival in 81 patients treated with imatinib mesylate. Cancer 2006; 106: 1617-23.
    • (2006) Cancer , vol.106 , pp. 1617-1623
    • Steinert, D.1    Oyarzo, M.2    Wang, X.3
  • 65
    • 9144238093 scopus 로고    scopus 로고
    • CD44 loss in gastric stromal tumors as a prognostic marker
    • Montgomery E, Abraham S, Fisher C., et al CD44 loss in gastric stromal tumors as a prognostic marker. Am J Surg Pathol 2004; 28: 168-77.
    • (2004) Am J Surg Pathol , vol.28 , pp. 168-177
    • Montgomery, E.1    Abraham, S.2    Fisher, C.3
  • 66
    • 10744233692 scopus 로고    scopus 로고
    • Prognostic indicators for gastrointestinal stromal tumours: A clinicopathological and immunohistochemical study of 108 resected cases of the stomach
    • Wong N, Young R, Malcomson R., et al Prognostic indicators for gastrointestinal stromal tumours: A clinicopathological and immunohistochemical study of 108 resected cases of the stomach. Histopathol 2003; 43: 118-26.
    • (2003) Histopathol , vol.43 , pp. 118-126
    • Wong, N.1    Young, R.2    Malcomson, R.3


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