메뉴 건너뛰기




Volumn 84, Issue 1, 2014, Pages 79-85

Clinical significance of the neutrophil-lymphocyte ratio in venous thromboembolism patients with lung cancer

Author keywords

Deep vein thrombosis; Lung neoplasms; Lymphocytes; Neutrophils; Pulmonary thromboembolism

Indexed keywords

ALBUMIN; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CHOLESTEROL; D DIMER; FIBRIN DEGRADATION PRODUCT; FIBRINOGEN; FRUCTOSE BISPHOSPHATE; HEMOGLOBIN; LOW MOLECULAR WEIGHT HEPARIN; PROTEIN; PROTHROMBIN; WARFARIN;

EID: 84896737593     PISSN: 01695002     EISSN: 18728332     Source Type: Journal    
DOI: 10.1016/j.lungcan.2014.01.014     Document Type: Article
Times cited : (39)

References (39)
  • 1
    • 84878484350 scopus 로고    scopus 로고
    • Cancer-associated thrombosis: updates and controversies
    • Khorana A.A. Cancer-associated thrombosis: updates and controversies. Hematol Am Soc Hematol Educ Progr 2012, 2012:626-630.
    • (2012) Hematol Am Soc Hematol Educ Progr , vol.2012 , pp. 626-630
    • Khorana, A.A.1
  • 2
    • 34748888394 scopus 로고    scopus 로고
    • Risk of venous thromboembolism in lung cancer
    • Tesselaar M.E., Osanto S. Risk of venous thromboembolism in lung cancer. Curr Opin Pulm Med 2007, 13:362-367.
    • (2007) Curr Opin Pulm Med , vol.13 , pp. 362-367
    • Tesselaar, M.E.1    Osanto, S.2
  • 3
    • 13244250995 scopus 로고    scopus 로고
    • The risk of a venous thrombotic event in lung cancer patients: higher risk for adenocarcinoma than squamous cell carcinoma
    • Blom J.W., Osanto S., Rosendaal F.R. The risk of a venous thrombotic event in lung cancer patients: higher risk for adenocarcinoma than squamous cell carcinoma. J Thromb Haemost 2004, 2:1760-1765.
    • (2004) J Thromb Haemost , vol.2 , pp. 1760-1765
    • Blom, J.W.1    Osanto, S.2    Rosendaal, F.R.3
  • 4
    • 34548400720 scopus 로고    scopus 로고
    • High risk of deep vein thrombosis in patients with non-small cell lung cancer: a cohort study of 493 patients
    • Tagalakis V., Levi D., Agulnik J.S., Cohen V., Kasymjanova G., Small D. High risk of deep vein thrombosis in patients with non-small cell lung cancer: a cohort study of 493 patients. J Thorac Oncol 2007, 2:729-734.
    • (2007) J Thorac Oncol , vol.2 , pp. 729-734
    • Tagalakis, V.1    Levi, D.2    Agulnik, J.S.3    Cohen, V.4    Kasymjanova, G.5    Small, D.6
  • 5
    • 84887235350 scopus 로고    scopus 로고
    • Prevalence and clinical significance of incidental and clinically suspected venous thromboembolism in lung cancer patients
    • Connolly G.C., Menapace L., Safadjou S., Francis C.W., Khorana A.A. Prevalence and clinical significance of incidental and clinically suspected venous thromboembolism in lung cancer patients. Clin Lung Cancer 2013, 14:713-718.
    • (2013) Clin Lung Cancer , vol.14 , pp. 713-718
    • Connolly, G.C.1    Menapace, L.2    Safadjou, S.3    Francis, C.W.4    Khorana, A.A.5
  • 6
    • 84868196308 scopus 로고    scopus 로고
    • Incidence of venous thromboembolism among chemotherapy-treated patients with lung cancer and its association with mortality: a retrospective database study
    • Huang H., Korn J.R., Mallick R., Friedman M., Nichols C., Menzin J. Incidence of venous thromboembolism among chemotherapy-treated patients with lung cancer and its association with mortality: a retrospective database study. J Thromb Thrombolysis 2012, 34:446-456.
    • (2012) J Thromb Thrombolysis , vol.34 , pp. 446-456
    • Huang, H.1    Korn, J.R.2    Mallick, R.3    Friedman, M.4    Nichols, C.5    Menzin, J.6
  • 7
    • 72249085780 scopus 로고    scopus 로고
    • Venous thromboembolism and nonsmall cell lung cancer: a pooled analysis of National Cancer Institute of Canada Clinical Trials Group trials
    • Hicks L.K., Cheung M.C., Ding K., Hasan B., Seymour L., Le Maitre A., et al. Venous thromboembolism and nonsmall cell lung cancer: a pooled analysis of National Cancer Institute of Canada Clinical Trials Group trials. Cancer 2009, 115:5516-5525.
    • (2009) Cancer , vol.115 , pp. 5516-5525
    • Hicks, L.K.1    Cheung, M.C.2    Ding, K.3    Hasan, B.4    Seymour, L.5    Le Maitre, A.6
  • 10
    • 84874270267 scopus 로고    scopus 로고
    • The emerging role of neutrophils in thrombosis - the journey of TF through NETs
    • Kambas K., Mitroulis I., Ritis K. The emerging role of neutrophils in thrombosis - the journey of TF through NETs. Front Immunol 2012, 3:385.
    • (2012) Front Immunol , vol.3 , pp. 385
    • Kambas, K.1    Mitroulis, I.2    Ritis, K.3
  • 11
    • 84864650304 scopus 로고    scopus 로고
    • Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis
    • Demers M., Krause D.S., Schatzberg D., Martinod K., Voorhees J.R., Fuchs T.A., et al. Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis. Proc Natl Acad Sci USA 2012, 109:13076-13081.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 13076-13081
    • Demers, M.1    Krause, D.S.2    Schatzberg, D.3    Martinod, K.4    Voorhees, J.R.5    Fuchs, T.A.6
  • 12
    • 84896697064 scopus 로고    scopus 로고
    • Neutrophil-lymphocyte ratio (NLR) as a simple and novel biomarker for prediction of locoregional recurrence after chemoradiotherapy for squamous cell carcinoma (SCC) of the anus
    • [Epub ahead of print]
    • Toh E., Wilson J., Sebag-Montefiore D., Botterill I. Neutrophil-lymphocyte ratio (NLR) as a simple and novel biomarker for prediction of locoregional recurrence after chemoradiotherapy for squamous cell carcinoma (SCC) of the anus. Colorectal Dis 2013, [Epub ahead of print].
    • (2013) Colorectal Dis
    • Toh, E.1    Wilson, J.2    Sebag-Montefiore, D.3    Botterill, I.4
  • 13
    • 84877057575 scopus 로고    scopus 로고
    • Elevated preoperative neutrophil/lymphocyte ratio is associated with poor prognosis in soft-tissue sarcoma patients
    • Szkandera J., Absenger G., Liegl-Atzwanger B., Pichler M., Stotz M., Samonigg H., et al. Elevated preoperative neutrophil/lymphocyte ratio is associated with poor prognosis in soft-tissue sarcoma patients. Br J Cancer 2013, 108:1677-1683.
    • (2013) Br J Cancer , vol.108 , pp. 1677-1683
    • Szkandera, J.1    Absenger, G.2    Liegl-Atzwanger, B.3    Pichler, M.4    Stotz, M.5    Samonigg, H.6
  • 14
    • 84880334569 scopus 로고    scopus 로고
    • Prognostic significance of neutrophil lymphocyte ratio and platelet lymphocyte ratio in advanced gastric cancer patients treated with FOLFOX chemotherapy
    • Lee S., Oh S.Y., Kim S.H., Lee J.H., Kim M.C., Kim K.H., et al. Prognostic significance of neutrophil lymphocyte ratio and platelet lymphocyte ratio in advanced gastric cancer patients treated with FOLFOX chemotherapy. BMC Cancer 2013, 13:350.
    • (2013) BMC Cancer , vol.13 , pp. 350
    • Lee, S.1    Oh, S.Y.2    Kim, S.H.3    Lee, J.H.4    Kim, M.C.5    Kim, K.H.6
  • 15
    • 79954430604 scopus 로고    scopus 로고
    • Neutrophil/lymphocyte ratio predicts chemotherapy outcomes in patients with advanced colorectal cancer
    • Chua W., Charles K.A., Baracos V.E., Clarke S.J. Neutrophil/lymphocyte ratio predicts chemotherapy outcomes in patients with advanced colorectal cancer. Br J Cancer 2011, 104:1288-1295.
    • (2011) Br J Cancer , vol.104 , pp. 1288-1295
    • Chua, W.1    Charles, K.A.2    Baracos, V.E.3    Clarke, S.J.4
  • 16
    • 84881115045 scopus 로고    scopus 로고
    • Increased neutrophil-lymphocyte ratio is a poor prognostic factor in patients with primary operable and inoperable pancreatic cancer
    • Stotz M., Gerger A., Eisner F., Szkandera J., Loibner H., Ress A.L., et al. Increased neutrophil-lymphocyte ratio is a poor prognostic factor in patients with primary operable and inoperable pancreatic cancer. Br J Cancer 2013, 109:416-421.
    • (2013) Br J Cancer , vol.109 , pp. 416-421
    • Stotz, M.1    Gerger, A.2    Eisner, F.3    Szkandera, J.4    Loibner, H.5    Ress, A.L.6
  • 17
    • 84887803609 scopus 로고    scopus 로고
    • Are neutrophil/lymphocyte and platelet/lymphocyte rates in patients with non-small cell lung cancer associated with treatment response and prognosis?
    • Unal D., Eroglu C., Kurtul N., Oguz A., Tasdemir A. Are neutrophil/lymphocyte and platelet/lymphocyte rates in patients with non-small cell lung cancer associated with treatment response and prognosis?. Asian Pac J Cancer Prev 2013, 14:5237-5242.
    • (2013) Asian Pac J Cancer Prev , vol.14 , pp. 5237-5242
    • Unal, D.1    Eroglu, C.2    Kurtul, N.3    Oguz, A.4    Tasdemir, A.5
  • 18
    • 58649105512 scopus 로고    scopus 로고
    • Neutrophil/lymphocyte ratio and its association with survival after complete resection in non-small cell lung cancer
    • Sarraf K.M., Belcher E., Raevsky E., Nicholson A.G., Goldstraw P., Lim E. Neutrophil/lymphocyte ratio and its association with survival after complete resection in non-small cell lung cancer. J Thorac Cardiovasc Surg 2009, 137:425-428.
    • (2009) J Thorac Cardiovasc Surg , vol.137 , pp. 425-428
    • Sarraf, K.M.1    Belcher, E.2    Raevsky, E.3    Nicholson, A.G.4    Goldstraw, P.5    Lim, E.6
  • 19
    • 84892798809 scopus 로고    scopus 로고
    • Neutrophil:lymphocyte ratio and intraoperative use of ketorolac or diclofenac are prognostic factors in different cohorts of patients undergoing breast, lung, and kidney cancer surgery
    • Forget P., Machiels J.P., Coulie P.G., Berliere M., Poncelet A.J., Tombal B., et al. Neutrophil:lymphocyte ratio and intraoperative use of ketorolac or diclofenac are prognostic factors in different cohorts of patients undergoing breast, lung, and kidney cancer surgery. Ann Surg Oncol 2013, 20:650-660.
    • (2013) Ann Surg Oncol , vol.20 , pp. 650-660
    • Forget, P.1    Machiels, J.P.2    Coulie, P.G.3    Berliere, M.4    Poncelet, A.J.5    Tombal, B.6
  • 20
    • 84865698629 scopus 로고    scopus 로고
    • Elevated preoperative inflammatory markers based on neutrophil-to-lymphocyte ratio and C-reactive protein predict poor survival in resected non-small cell lung cancer
    • Tomita M., Shimizu T., Ayabe T., Nakamura K., Onitsuka T. Elevated preoperative inflammatory markers based on neutrophil-to-lymphocyte ratio and C-reactive protein predict poor survival in resected non-small cell lung cancer. Anticancer Res 2012, 32:3535-3538.
    • (2012) Anticancer Res , vol.32 , pp. 3535-3538
    • Tomita, M.1    Shimizu, T.2    Ayabe, T.3    Nakamura, K.4    Onitsuka, T.5
  • 21
    • 84877127474 scopus 로고    scopus 로고
    • Pretreatment neutrophil to lymphocyte ratio is associated with response to therapy and prognosis of advanced non-small cell lung cancer patients treated with first-line platinum-based chemotherapy
    • Yao Y., Yuan D., Liu H., Gu X., Song Y. Pretreatment neutrophil to lymphocyte ratio is associated with response to therapy and prognosis of advanced non-small cell lung cancer patients treated with first-line platinum-based chemotherapy. Cancer Immunol Immunother 2013, 62:471-479.
    • (2013) Cancer Immunol Immunother , vol.62 , pp. 471-479
    • Yao, Y.1    Yuan, D.2    Liu, H.3    Gu, X.4    Song, Y.5
  • 22
    • 84871211511 scopus 로고    scopus 로고
    • Neutrophil to lymphocyte ratio (NLR) as an indicator of poor prognosis in stage IV non-small cell lung cancer
    • Cedres S., Torrejon D., Martinez A., Martinez P., Navarro A., Zamora E., et al. Neutrophil to lymphocyte ratio (NLR) as an indicator of poor prognosis in stage IV non-small cell lung cancer. Clin Transl Oncol 2012, 14:864-869.
    • (2012) Clin Transl Oncol , vol.14 , pp. 864-869
    • Cedres, S.1    Torrejon, D.2    Martinez, A.3    Martinez, P.4    Navarro, A.5    Zamora, E.6
  • 23
    • 84871314231 scopus 로고    scopus 로고
    • Early neutrophil-to-lymphocyte ratio reduction as a surrogate marker of prognosis in never smokers with advanced lung adenocarcinoma receiving gefitinib or standard chemotherapy as first-line therapy
    • Lee Y., Kim S.H., Han J.Y., Kim H.T., Yun T., Lee J.S. Early neutrophil-to-lymphocyte ratio reduction as a surrogate marker of prognosis in never smokers with advanced lung adenocarcinoma receiving gefitinib or standard chemotherapy as first-line therapy. J Cancer Res Clin Oncol 2012, 138:2009-2016.
    • (2012) J Cancer Res Clin Oncol , vol.138 , pp. 2009-2016
    • Lee, Y.1    Kim, S.H.2    Han, J.Y.3    Kim, H.T.4    Yun, T.5    Lee, J.S.6
  • 24
    • 84896717718 scopus 로고    scopus 로고
    • Prognostic value of the neutrophil-lymphocyte ratio in patients with ST-elevated acute myocardial infarction
    • [Epub ahead of print]
    • Gazi E., Bayram B., Gazi S., Temiz A., Kirilmaz B., Altun B., et al. Prognostic value of the neutrophil-lymphocyte ratio in patients with ST-elevated acute myocardial infarction. Clin Appl Thromb Hemost 2013, [Epub ahead of print].
    • (2013) Clin Appl Thromb Hemost
    • Gazi, E.1    Bayram, B.2    Gazi, S.3    Temiz, A.4    Kirilmaz, B.5    Altun, B.6
  • 25
    • 84876796078 scopus 로고    scopus 로고
    • The neutrophil to lymphocyte ratio was associated with impaired myocardial perfusion and long term adverse outcome in patients with ST-elevated myocardial infarction undergoing primary coronary intervention
    • Sen N., Afsar B., Ozcan F., Buyukkaya E., Isleyen A., Akcay A.B., et al. The neutrophil to lymphocyte ratio was associated with impaired myocardial perfusion and long term adverse outcome in patients with ST-elevated myocardial infarction undergoing primary coronary intervention. Atherosclerosis 2013, 228:203-210.
    • (2013) Atherosclerosis , vol.228 , pp. 203-210
    • Sen, N.1    Afsar, B.2    Ozcan, F.3    Buyukkaya, E.4    Isleyen, A.5    Akcay, A.B.6
  • 26
    • 84896728510 scopus 로고    scopus 로고
    • Predictive value of neutrophil to lymphocyte ratio in clinical outcomes of non-ST elevation myocardial infarction and unstable angina pectoris: a 3-year follow-up
    • [Epub ahead of print]
    • Gul M., Uyarel H., Ergelen M., Ugur M., Isik T., Ayhan E., et al. Predictive value of neutrophil to lymphocyte ratio in clinical outcomes of non-ST elevation myocardial infarction and unstable angina pectoris: a 3-year follow-up. Clin Appl Thromb Hemost 2012, [Epub ahead of print].
    • (2012) Clin Appl Thromb Hemost
    • Gul, M.1    Uyarel, H.2    Ergelen, M.3    Ugur, M.4    Isik, T.5    Ayhan, E.6
  • 27
    • 84885320185 scopus 로고    scopus 로고
    • Prognostic value of neutrophil/lymphocyte ratio in patients with ST-elevated myocardial infarction undergoing primary coronary intervention: a prospective, multicenter study
    • Kaya M.G., Akpek M., Lam Y.Y., Yarlioglues M., Celik T., Gunebakmaz O., et al. Prognostic value of neutrophil/lymphocyte ratio in patients with ST-elevated myocardial infarction undergoing primary coronary intervention: a prospective, multicenter study. Int J Cardiol 2013, 168:1154-1159.
    • (2013) Int J Cardiol , vol.168 , pp. 1154-1159
    • Kaya, M.G.1    Akpek, M.2    Lam, Y.Y.3    Yarlioglues, M.4    Celik, T.5    Gunebakmaz, O.6
  • 28
    • 79952312895 scopus 로고    scopus 로고
    • Value of early risk stratification using hemoglobin level and neutrophil-to-lymphocyte ratio in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention
    • Cho K.H., Jeong M.H., Ahmed K., Hachinohe D., Choi H.S., Chang S.Y., et al. Value of early risk stratification using hemoglobin level and neutrophil-to-lymphocyte ratio in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention. Am J Cardiol 2011, 107:849-856.
    • (2011) Am J Cardiol , vol.107 , pp. 849-856
    • Cho, K.H.1    Jeong, M.H.2    Ahmed, K.3    Hachinohe, D.4    Choi, H.S.5    Chang, S.Y.6
  • 30
    • 31544478042 scopus 로고    scopus 로고
    • Risk factors for venous thromboembolic events in cancer patients
    • Kroger K., Weiland D., Ose C., Neumann N., Weiss S., Hirsch C., et al. Risk factors for venous thromboembolic events in cancer patients. Ann Oncol 2006, 17:297-303.
    • (2006) Ann Oncol , vol.17 , pp. 297-303
    • Kroger, K.1    Weiland, D.2    Ose, C.3    Neumann, N.4    Weiss, S.5    Hirsch, C.6
  • 32
    • 77955410626 scopus 로고    scopus 로고
    • Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases
    • Massberg S., Grahl L., von Bruehl M.L., Manukyan D., Pfeiler S., Goosmann C., et al. Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases. Nat Med 2010, 16:887-896.
    • (2010) Nat Med , vol.16 , pp. 887-896
    • Massberg, S.1    Grahl, L.2    von Bruehl, M.L.3    Manukyan, D.4    Pfeiler, S.5    Goosmann, C.6
  • 33
    • 84861750668 scopus 로고    scopus 로고
    • Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo
    • von Bruhl M.L., Stark K., Steinhart A., Chandraratne S., Konrad I., Lorenz M., et al. Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo. J Exp Med 2012, 209:819-835.
    • (2012) J Exp Med , vol.209 , pp. 819-835
    • von Bruhl, M.L.1    Stark, K.2    Steinhart, A.3    Chandraratne, S.4    Konrad, I.5    Lorenz, M.6
  • 34
    • 84881249503 scopus 로고    scopus 로고
    • Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis
    • Cools-Lartigue J., Spicer J., McDonald B., Gowing S., Chow S., Giannias B., et al. Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis. J Clin Invest 2013, 123:3446-3458.
    • (2013) J Clin Invest , vol.123 , pp. 3446-3458
    • Cools-Lartigue, J.1    Spicer, J.2    McDonald, B.3    Gowing, S.4    Chow, S.5    Giannias, B.6
  • 35
    • 84885925936 scopus 로고    scopus 로고
    • Neutrophil extracellular traps: a new link to cancer-associated thrombosis and potential implications for tumor progression
    • Demers M., Wagner D.D. Neutrophil extracellular traps: a new link to cancer-associated thrombosis and potential implications for tumor progression. Oncoimmunology 2013, 2:e22946.
    • (2013) Oncoimmunology , vol.2
    • Demers, M.1    Wagner, D.D.2
  • 37
    • 84866554641 scopus 로고    scopus 로고
    • Autophagy mediates the delivery of thrombogenic tissue factor to neutrophil extracellular traps in human sepsis
    • Kambas K., Mitroulis I., Apostolidou E., Girod A., Chrysanthopoulou A., Pneumatikos I., et al. Autophagy mediates the delivery of thrombogenic tissue factor to neutrophil extracellular traps in human sepsis. PLoS ONE 2012, 7:e45427.
    • (2012) PLoS ONE , vol.7
    • Kambas, K.1    Mitroulis, I.2    Apostolidou, E.3    Girod, A.4    Chrysanthopoulou, A.5    Pneumatikos, I.6
  • 38
    • 84887587702 scopus 로고    scopus 로고
    • Biomarkers for prediction of venous thromboembolism in cancer
    • Pabinger I., Thaler J., Ay C. Biomarkers for prediction of venous thromboembolism in cancer. Blood 2013, 122:2011-2018.
    • (2013) Blood , vol.122 , pp. 2011-2018
    • Pabinger, I.1    Thaler, J.2    Ay, C.3
  • 39
    • 0345530028 scopus 로고    scopus 로고
    • Interaction of vascular endothelial cells with leukocytes, platelets and cancer cells in inflammation, thrombosis and cancer growth and metastasis
    • Geng J.G. Interaction of vascular endothelial cells with leukocytes, platelets and cancer cells in inflammation, thrombosis and cancer growth and metastasis. Acta Pharmacol Sin 2003, 24:1297-1300.
    • (2003) Acta Pharmacol Sin , vol.24 , pp. 1297-1300
    • Geng, J.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.