Proteomic analysis of whole glomeruli in patients with igA nephropathy using microsieving

American Journal of Nephrology

Volumn 39, Issue 1, 2014, Pages 36-45

  Kojima, Shigeki ^a,b   Koitabashi, Kenichiro ^b   Iizuka, Nobuko ^a   Okamoto, Kazuki ^a   Arito, Mitsumi ^a   Sato, Toshiyuki ^a   Kurokawa, Manae S ^a   Suematsu, Naoya ^a   Shibagaki, Yugo ^b   Yasuda, Takashi ^b   Kimura, Kenjiro ^b   Kato, Tomohiro ^a  

^a ST MARIANNA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Actinin 4; Lga nephropathy; Microsieving; Minimal change nephrotic syndrome; Proteomics

Indexed keywords

ALDEHYDE DEHYDROGENASE; ALPHA ACTININ 4; ALPHA ENOLASE; CLUSTERIN; COMPLEMENT COMPONENT C3; ELONGATION FACTOR TU; GLYCINE AMIDINOTRANSFERASE; IMMUNOGLOBULIN A2; LAMIN A; LAMIN C; MEDIUM CHAIN ACYL COENZYME A DEHYDROGENASE; MESSENGER RNA; SYNTROPHIN; VIMENTIN; ACYL COENZYME A DEHYDROGENASE; BETA 1 SYNTROPHIN; TRIPHENYLTETRAZOLIUM; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ALTERNATIVE RNA SPLICING; ARTICLE; CAPILLARY WALL; CLINICAL ARTICLE; FEMALE; GLOMERULUS; HUMAN; HUMAN TISSUE; IMMUNOGLOBULIN A NEPHROPATHY; IMMUNOHISTOCHEMISTRY; KIDNEY BIOPSY; MALE; MASS SPECTROMETRY; MICROSIEVING; MIDDLE AGED; MINIMAL CHANGE GLOMERULONEPHRITIS; MOLECULAR WEIGHT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEOMICS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TWO DIMENSIONAL GEL ELECTROPHORESIS; WESTERN BLOTTING; YOUNG ADULT; COMPARATIVE STUDY; GEL ELECTROPHORESIS; GLOMERULOPATHY; KIDNEY DONOR; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NEPHROTIC SYNDROME; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; PROTEIN FOLDING; TWO DIMENSIONAL DIFFERENCE GEL ELECTROPHORESIS;

ACTININ; ADOLESCENT; ADULT; BIOPSY; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FEMALE; GLOMERULONEPHRITIS, IGA; HUMANS; KIDNEY; KIDNEY GLOMERULUS; MALE; MASS SPECTROMETRY; MIDDLE AGED; NEPHROSIS, LIPOID; PROTEIN STRUCTURE, TERTIARY; PROTEOMICS; YOUNG ADULT;

EID: 84896736554     PISSN: 02508095     EISSN: 14219670     Source Type: Journal    
DOI: 10.1159/000357788     Document Type: Article

References (34)

1. Berger J, Hinglais N: Intercapillary deposits of IgA-IgG. J Urol Nephrol (Paris) 1968; 74: 694-695.
2. Suzuki S, Fujieda S, Sunaga H, Sugimoto H, Yamamoto C, Kimura H, Abo T, Gejyo F: Immune response of tonsillar lymphocytes to Haemophilus parainfluenzae in patients with IgA nephropathy. Clin Exp Immunol 2000; 119: 328-332.
3. Yamamoto C, Suzuki S, Kimura H, Yoshida H, Gejyo F: Experimental nephropathy induced by Haemophilus parainfluenzae antigens. Nephron 2002; 90: 320-327.
4. Suzuki Y, Tomino Y: The mucosa-bone-marrow axis in IgA nephropathy. Contrib Nephrol. Basel, Karger, 2007, vol 157, pp 70-79.
5. Suzuki Y, Tomino Y: Potential immunopathogenic role of the mucosa-bone marrow axis in IgA nephropathy: insights from animal models. Semin Nephrol 2008; 28: 66-77.
6. Barratt J, Feehally J, Smith AC: Pathogenesis of IgA nephropathy. Semin Nephrol 2004; 24: 197-217.
7. Moldoveanu Z, Wyatt RJ, Lee JY, Tomana M, Julian BA, Mestecky J, Huang WQ, Anreddy SR, Hall S, Hastings MC, Lau KK, Cook WJ, Novak J: Patients with IgA nephropathy have increased serum galactose-deficient IgA1 levels. Kidney Int 2007; 71: 1148-1154.
8. Satoskar AA, Shapiro JP, Bott CN, Song H, Nadasdy GM, Brodsky SV, Hebert LA, Birmingham DJ, Nadasdy T, Freitas MA, Rovin BH: Characterization of glomerular diseases using proteomic analysis of laser capture microdissected glomeruli. Mod Pathol 2012; 25: 709-721.
9. Koitabashi K, Okamoto K, Arirto M, Sato T, Nagai K, Kurokawa MS, Suematsu N, Yasuda T, Kimura K, Kato T: Micro-sieving: isolation of whole glomeruli from a single renal needle biopsy sample. Nephron Clin Pract 2011; 117:c225-c229.
10. Berger J, IgA glomerular deposits in renal disease. Transplant Proc 1969; 1: 939-944.
11. Saha TC, Singh H: Minimal change disease: a review. South Med J 2006; 99: 1264-1270.
12. Shimada S, Nakamura M, Tanaka Y, Tsutsumi K, Katano M, Masuko K, Yudoh K, Koizuka I, Kato T: Crosslinking of the CD69 molecule enhances S100A9 production in activated neutrophils. Microbiol Immunol 2007; 51: 87-98.
13. Okunuki Y, Usui Y, Takeuchi M, Kezuka T, Hattori T, Masuko K, Nakamura H, Yudoh K, Usui M, Nishioka K, Kato T: Proteomic surveillance of autoimmunity in Behcet's disease with uveitis: selenium binding protein is a novel autoantigen in Behcet's disease. Exp Eye Res 2007; 84: 823-831.
14. Working Group of the International IgA Nephropathy Network and the Renal Pathology Society, Cattran DC, Coppo R, Cook HT, Feehally J, Roberts IS, Troyanov S, Alpers CE, Amore A, Barratt J, Berthoux F, Bonsib S, Bruijn JA, D'Agati V, D'Amico G, Emancipator S, Emma F, Ferrario F, Fervenza FC, Florquin S, Fogo A, Geddes CC, Groene HJ, Haas M, Herzenberg AM, Hill PA, Hogg RJ, Hsu SI, Jennette JC, Joh K, Julian BA, Kawamura T, Lai FM, Leung CB, Li LS, Li PK, Liu ZH, Mackinnon B, Mezzano S, Schena FP, Tomino Y, Walker PD, Wang H, Weening JJ, Yoshikawa N, Zhang H: The Oxford classification of IgA nephropathy: rationale, clinicopathological correlations, and classification. Kidney Int 2009; 76: 534-545.
15. Sitek B, Potthoff S, Schulenborg T, Stegbauer J, Vinke T, Rump LC, Meyer HE, Vonend O, Stuhler K: Novel approaches to analyse glomerular proteins from smallest scale murine and human samples using DIGE saturation labelling. Proteomics 2006; 6: 4337-4345.
16. Moura IC, Centelles MN, Arcos-Fajardo M, Malheiros DM, Collawn JF, Cooper MD, Monteiro RC: Identification of the transferrin receptor as a novel immunoglobulin (Ig)A1 receptor and its enhanced expression on mesangial cells in IgA nephropathy. J Exp Med 2001; 194: 417-425.
17. Suzuki S, Nakatomi Y, Sato H, Tsukada H, Arakawa M: Haemophilus parainfluenzae antigen and antibody in renal biopsy samples and serum of patients with IgA nephropathy. Lancet 1994; 343: 12-16.
18. Koyama A, Sharmin S, Sakurai H, Shimizu Y, Hirayama K, Usui J, Nagata M, Yoh K, Yamagata K, Muro K, Kobayashi M, Ohtani K, Shimizu T, Shimizu T: Staphylococcus aureus cell envelope antigen is a new candidate for the induction of IgA nephropathy. Kidney Int 2004; 66: 121-132.
19. Christerson LB, Vanderbilt CA, Cobb MH: MEKK1 interacts with alpha-actinin and localizes to stress fibers and focal adhesions. Cell Motil Cytoskeleton 1999; 43: 186-198.
20. Greenwood JA, Theibert AB, Prestwich GD, Murphy-Ullrich JE: Restructuring of focal adhesion plaques by PI 3-kinase. Regulation by PtdIns (3,4,5)-p(3) binding to alpha-actinin. J Cell Biol 2000; 150: 627-642.
21. Oikonomou KG, Zachou K, Dalekos GN: Alpha- actinin: a multidisciplinary protein with important role in B-cell driven autoimmunity. Autoimmun Rev 2011; 10: 389-396.
22. Dai C, Stolz DB, Bastacky SI, St-Arnaud R, Wu C, Dedhar S, Liu Y: Essential role of integrin- linked kinase in podocyte biology: bridging the integrin and slit diaphragm signaling. J Am Soc Nephrol 2006; 17: 2164-2175.
23. Kaplan JM, Kim SH, North KN, Rennke H, Correia LA, Tong HQ, Mathis BJ, Rodriguez- Perez JC, Allen PG, Beggs AH, Pollak MR: Mutations in ACTN4, encoding alpha-actinin- 4, cause familial focal segmental glomerulosclerosis. Nat Genet 2000; 24: 251-256.
24. Deocharan B, Qing X, Lichauco J, Putterman C: Alpha-actinin is a cross-reactive renal target for pathogenic anti-DNA antibodies. J Immunol 2002; 168: 3072-3078.
25. Honda K, Yamada T, Endo R, Ino Y, Gotoh M, Tsuda H, Yamada Y, Chiba H, Hirohashi S: Actinin-4, a novel actin-bundling protein associated with cell motility and cancer invasion. J Cell Biol 1998; 140: 1383-1393.
26. Noro R, Honda K, Tsuta K, Ishii G, Maeshima AM, Miura N, Furuta K, Shibata T, Tsuda H, Ochiai A, Sakuma T, Nishijima N, Gemma A, Asamura H, Nagai K, Yamada T: Distinct outcome of stage I lung adenocarcinoma with ACTN4 cell motility gene amplification. Ann Oncol 2013; 24: 2594-2600.
27. Luikart S, Masri M, Wahl D, Hinkel T, Beck JM, Gyetko MR, Gupta P, Oegema T: Urokinase is required for the formation of mactinin, an alpha-actinin fragment that promotes monocyte/macrophage maturation. Biochim Biophys Acta 2002; 1591: 99-107.
28. Goode NP, Shires M, Khan TN, Mooney AF: Expression of alpha-actinin-4 in acquired human nephrotic syndrome: a quantitative immunoelectron microscopy study. Nephrol Dial Transplant 2004; 19: 844-851.
29. Nazeer K, Janech MG, Lin JJ, Ryan KJ, Arthur JM, Budisavljevic MN: Changes in protein profiles during course of experimental glomerulonephritis. Am J Physiol Renal Physiol 2009; 296:F186-F193.
30. Ivaska J, Pallari HM, Nevo J, Eriksson JE: Novel functions of vimentin in cell adhesion, migration, and signaling. Exp Cell Res 2007; 313: 2050-2062.
31. Srivastava T, Garola RE, Whiting JM, Alon US: Synaptopodin expression in idiopathic nephrotic syndrome of childhood. Kidney Int 2001; 59: 118-125.
32. Jiang L, Ding J, Tsai H, Li L, Feng Q, Miao J, Fan Q: Over-expressing transient receptor potential cation channel 6 in podocytes induces cytoskeleton rearrangement through increases of intracellular Ca2+ and RhoA activation. Exp Biol Med (Maywood) 2011; 236: 184-193.
33. Brockstedt E, Otto A, Rickers A, Bommert K, Wittmann-Liebold B: Preparative high-resolution two-dimensional electrophoresis enables the identification of RNA polymerase B transcription factor 3 as an apoptosis-associated protein in the human BL60-2 Burkitt lymphoma cell line. J Protein Chem 1999; 18: 225-231.
34. Wang Y, Wang X, Zhao H, Liang B, Du Q: Clusterin confers resistance to TNF-alpha-induced apoptosis in breast cancer cells through NF-kappaB activation and Bcl-2 overexpression. J Chemother 2012; 24: 348-357.