-
1
-
-
33947279386
-
Suicide gene therapy with adenoviral delivery of HSV-tK gene for patients with local recurrence of prostate cancer after hormonal therapy
-
DOI 10.1038/sj.mt.6300096, PII 6300096
-
Nasu Y, Saika T, Ebara S, Kusaka N, Kaku H, Abarzua F, Manabe D, Thompson TC and Kumon H: Suicide gene therapy with adenoviral delivery of HSV-tK gene for patients with local recurrence of prostate cancer after hormonal therapy. Mol Ther 15: 834-840, 2007. (Pubitemid 46432005)
-
(2007)
Molecular Therapy
, vol.15
, Issue.4
, pp. 834-840
-
-
Nasu, Y.1
Saika, T.2
Ebara, S.3
Kusaka, N.4
Kaku, H.5
Abarzua, F.6
Manabe, D.7
Thompson, T.C.8
Kumon, H.9
-
2
-
-
70549110920
-
Adenovirus-mediated cancer gene therapy and virotherapy
-
Review
-
Fukazawa T, Matsuoka J, Yamatsuji T, Maeda Y, Durbin ML and Naomoto Y: Adenovirus-mediated cancer gene therapy and virotherapy (Review). Int J Mol Med 25: 3-10, 2010.
-
(2010)
Int J Mol Med
, vol.25
, pp. 3-10
-
-
Fukazawa, T.1
Matsuoka, J.2
Yamatsuji, T.3
Maeda, Y.4
Durbin, M.L.5
Naomoto, Y.6
-
3
-
-
0025884056
-
Efficient selection for high-expression transfectants with a novel eukaryotic vector
-
Niwa H, Yamamura K and Miyazaki J: Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene 108: 193-199, 1991.
-
(1991)
Gene
, vol.108
, pp. 193-199
-
-
Niwa, H.1
Yamamura, K.2
Miyazaki, J.3
-
4
-
-
0028928854
-
Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase
-
Araki K, Araki M, Miyazaki J and Vassalli P: Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase. Proc Natl Acad Sci USA 92: 160-164, 1995.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 160-164
-
-
Araki, K.1
Araki, M.2
Miyazaki, J.3
Vassalli, P.4
-
5
-
-
0036968378
-
Gene therapy for prostate cancer: Toxicological profile of four HSV-tk transducing adenoviral vectors regulated by different promoters
-
DOI 10.1038/sj.pcan.4500610
-
Ebara S, Shimura S, Nasu Y, Kaku H, Kumon H, Yang G, Wang J, Timme TL, Aguilar-Cordova E and Thompson TC: Gene therapy for prostate cancer: toxicological profile of four HSV-tk transducing adenoviral vectors regulated by different promoters. Prostate Cancer Prostatic Dis 5: 316-325, 2002. (Pubitemid 36124444)
-
(2002)
Prostate Cancer and Prostatic Diseases
, vol.5
, Issue.4
, pp. 316-325
-
-
Ebara, E.1
Shimura, S.2
Nasu, Y.3
Kaku, H.4
Kumon, H.5
Yang, G.6
Wang, J.7
Timme, T.L.8
Aguilar-Cordova, E.9
Thompson, T.C.10
-
6
-
-
20844433717
-
Adeno-associated virus 2-mediated intratumoral prostate cancer gene therapy: Long-term maspin expression efficiently suppresses tumor growth
-
DOI 10.1089/hum.2005.16.699
-
Watanabe M, Nasu Y, Kashiwakura Y, Kusumi N, Tamayose K, Nagai A, Sasano T, Shimada T, Daida H and Kumon H: Adeno-associated virus 2-mediated intratumoral prostate cancer gene therapy: long-term maspin expression efficiently suppresses tumor growth. Hum Gene Ther 16: 699-710, 2005. (Pubitemid 40864270)
-
(2005)
Human Gene Therapy
, vol.16
, Issue.6
, pp. 699-710
-
-
Watanabe, M.1
Nasu, Y.2
Kashiwakura, Y.3
Kusumi, N.4
Tamayose, K.5
Nagai, A.6
Sasano, T.7
Shimada, T.8
Daida, H.9
Kumon, H.10
-
7
-
-
0035844986
-
Optimization of transcriptional regulatory elements for constructing plasmid vectors
-
DOI 10.1016/S0378-1119(01)00550-9, PII S0378111901005509
-
Xu ZL, Mizuguchi H, Ishii-Watabe A, Uchida E, Mayumi T and Hayakawa T: Optimization of transcriptional regulatory elements for constructing plasmid vectors. Gene 272: 149-156, 2001. (Pubitemid 32695407)
-
(2001)
Gene
, vol.272
, Issue.1-2
, pp. 149-156
-
-
Xu, Z.-L.1
Mizuguchi, H.2
Ishii-Watabe, A.3
Uchida, E.4
Mayumi, T.5
Hayakawa, T.6
-
8
-
-
0037123721
-
Strength evaluation of transcriptional regulatory elements for transgene expression by adenovirus vector
-
DOI 10.1016/S0168-3659(02)00059-7, PII S0168365902000597
-
Xu ZL, Mizuguchi H, Ishii-Watabe A, Uchida E, Mayumi T and Hayakawa T: Strength evaluation of transcriptional regulatory elements for transgene expression by adenovirus vector. J Control Release 81: 155-163, 2002. (Pubitemid 34454857)
-
(2002)
Journal of Controlled Release
, vol.81
, Issue.1-2
, pp. 155-163
-
-
Xu, Z.-L.1
Mizuguchi, H.2
Ishii-Watabe, A.3
Uchida, E.4
Mayumi, T.5
Hayakawa, T.6
-
9
-
-
0042025139
-
Effect of a DNA nuclear targeting sequence on gene transfer and expression of plasmids in the intact vasculature
-
DOI 10.1038/sj.gt.3302021
-
Young JL, Benoit JN and Dean DA: Effect of a DNA nuclear targeting sequence on gene transfer and expression of plasmids in the intact vasculature. Gene Ther 10: 1465-1470, 2003. (Pubitemid 36987140)
-
(2003)
Gene Therapy
, vol.10
, Issue.17
, pp. 1465-1470
-
-
Young, J.L.1
Benoit, J.N.2
Dean, D.A.3
-
10
-
-
15244362915
-
Enhanced expression of apoptin by the Myc-Max binding motif and SV40 enhancer for SCLC gene therapy
-
Song JS: Enhanced expression of apoptin by the Myc-Max binding motif and SV40 enhancer for SCLC gene therapy. Biosci Biotechnol Biochem 69: 51-55, 2005.
-
(2005)
Biosci Biotechnol Biochem
, vol.69
, pp. 51-55
-
-
Song, J.S.1
-
11
-
-
39049192223
-
Preferentially enhanced gene expression from a synthetic human telomerase reverse transcriptase promoter in human cancer cells
-
Kim SJ, Lee HS, Shin JH, Kim CG, Jeong S, Park K, Choe H and Lee H: Preferentially enhanced gene expression from a synthetic human telomerase reverse transcriptase promoter in human cancer cells. Oncol Rep 16: 975-979, 2006.
-
(2006)
Oncol Rep
, vol.16
, pp. 975-979
-
-
Kim, S.J.1
Lee, H.S.2
Shin, J.H.3
Kim, C.G.4
Jeong, S.5
Park, K.6
Choe, H.7
Lee, H.8
-
12
-
-
70349659628
-
A simple biological imaging system for detecting viable human circulating tumor cells
-
Kojima T, Hashimoto Y, Watanabe Y, Kagawa S, Uno F, Kuroda S, Tazawa H, Kyo S, Mizuguchi H, Urata Y, Tanaka N and Fujiwara T: A simple biological imaging system for detecting viable human circulating tumor cells. J Clin Invest 119: 3172-3181, 2009.
-
(2009)
J Clin Invest
, vol.119
, pp. 3172-3181
-
-
Kojima, T.1
Hashimoto, Y.2
Watanabe, Y.3
Kagawa, S.4
Uno, F.5
Kuroda, S.6
Tazawa, H.7
Kyo, S.8
Mizuguchi, H.9
Urata, Y.10
Tanaka, N.11
Fujiwara, T.12
-
13
-
-
79960816383
-
Advanced two-step transcriptional amplification as a novel method for cancer-specific gene expression and imaging
-
Watanabe M, Ueki H, Ochiai K, Huang P, Kobayashi Y, Nasu Y, Sasaki K, Kaku H, Kashiwakura Y and Kumon H: Advanced two-step transcriptional amplification as a novel method for cancer-specific gene expression and imaging. Oncol Rep 26: 769-775, 2011.
-
(2011)
Oncol Rep
, vol.26
, pp. 769-775
-
-
Watanabe, M.1
Ueki, H.2
Ochiai, K.3
Huang, P.4
Kobayashi, Y.5
Nasu, Y.6
Sasaki, K.7
Kaku, H.8
Kashiwakura, Y.9
Kumon, H.10
-
14
-
-
84862875342
-
A novel gene expression system for detecting viable bladder cancer cells
-
Ueki H, Watanabe M, Kaku H, Huang P, Li SA, Ochiai K, Hirata T, Noguchi H, Yamada H, Takei K, Nasu Y, Kashiwakura Y and Kumon H: A novel gene expression system for detecting viable bladder cancer cells. Int J Oncol 41: 135-140, 2012.
-
(2012)
Int J Oncol
, vol.41
, pp. 135-140
-
-
Ueki, H.1
Watanabe, M.2
Kaku, H.3
Huang, P.4
Li, S.A.5
Ochiai, K.6
Hirata, T.7
Noguchi, H.8
Yamada, H.9
Takei, K.10
Nasu, Y.11
Kashiwakura, Y.12
Kumon, H.13
-
15
-
-
0034607050
-
A REIC gene shows down-regulation in human immortalized cells and human tumor-derived cell lines
-
DOI 10.1006/bbrc.1999.2067
-
Tsuji T, Miyazaki M, Sakaguchi M, Inoue Y and Namba M: A REIC gene shows down-regulation in human immortalized cells and human tumor-derived cell lines. Biochem Biophys Res Commun 268: 20-24, 2000. (Pubitemid 30116603)
-
(2000)
Biochemical and Biophysical Research Communications
, vol.268
, Issue.1
, pp. 20-24
-
-
Tsuji, T.1
Miyazaki, M.2
Sakaguchi, M.3
Inoue, Y.4
Namba, M.5
-
16
-
-
27544457678
-
2-kinase
-
DOI 10.1158/0008-5472.CAN-05-0829
-
Abarzua F, Sakaguchi M, Takaishi M, Nasu Y, Kurose K, Ebara S, Miyazaki M, Namba M, Kumon H and Huh NH: Adenovirus-mediated overexpression of REIC/Dkk-3 selectively induces apoptosis in human prostate cancer cells through activation of c-Jun-NH2-kinase. Cancer Res 65: 9617-9622, 2005. (Pubitemid 41541434)
-
(2005)
Cancer Research
, vol.65
, Issue.21
, pp. 9617-9622
-
-
Abarzua, F.1
Sakaguchi, M.2
Takaishi, M.3
Nasu, Y.4
Kurose, K.5
Ebara, S.6
Miyazaki, M.7
Namba, M.8
Kumon, H.9
Huh, N.-H.10
-
17
-
-
54249161033
-
Down-regulation of inhibition of differentiation-1 via activation of activating transcription factor 3 and Smad regulates REIC/Dickkopf-3-induced apoptosis
-
Kashiwakura Y, Ochiai K, Watanabe M, Abarzua F, Sakaguchi M, Takaoka M, Tanimoto R, Nasu Y, Huh NH and Kumon H: Down-regulation of inhibition of differentiation-1 via activation of activating transcription factor 3 and Smad regulates REIC/Dickkopf-3-induced apoptosis. Cancer Res 68: 8333-8341, 2008.
-
(2008)
Cancer Res
, vol.68
, pp. 8333-8341
-
-
Kashiwakura, Y.1
Ochiai, K.2
Watanabe, M.3
Abarzua, F.4
Sakaguchi, M.5
Takaoka, M.6
Tanimoto, R.7
Nasu, Y.8
Huh, N.H.9
Kumon, H.10
-
18
-
-
57649122080
-
REIC/Dkk-3 overexpression downregulates P-glycoprotein in multidrug-resistant MCF7/ADR cells and induces apoptosis in breast cancer
-
Kawasaki K, Watanabe M, Sakaguchi M, Ogasawara Y, Ochiai K, Nasu Y, Doihara H, Kashiwakura Y, Huh NH, Kumon H and Date H: REIC/Dkk-3 overexpression downregulates P-glycoprotein in multidrug-resistant MCF7/ADR cells and induces apoptosis in breast cancer. Cancer Gene Ther 16: 65-72, 2009.
-
(2009)
Cancer Gene Ther
, vol.16
, pp. 65-72
-
-
Kawasaki, K.1
Watanabe, M.2
Sakaguchi, M.3
Ogasawara, Y.4
Ochiai, K.5
Nasu, Y.6
Doihara, H.7
Kashiwakura, Y.8
Huh, N.H.9
Kumon, H.10
Date, H.11
-
19
-
-
64549104285
-
Immunological aspects of REIC/Dkk-3 in monocyte differentiation and tumor regression
-
Watanabe M, Kashiwakura Y, Huang P, Ochiai K, Futami J, Li SA, Takaoka M, Nasu Y, Sakaguchi M, Huh NH and Kumon H: Immunological aspects of REIC/Dkk-3 in monocyte differentiation and tumor regression. Int J Oncol 34: 657-663, 2009.
-
(2009)
Int J Oncol
, vol.34
, pp. 657-663
-
-
Watanabe, M.1
Kashiwakura, Y.2
Huang, P.3
Ochiai, K.4
Futami, J.5
Li, S.A.6
Takaoka, M.7
Nasu, Y.8
Sakaguchi, M.9
Huh, N.H.10
Kumon, H.11
-
20
-
-
67649827862
-
Overexpression of REIC/Dkk-3 in normal fibroblasts suppresses tumor growth via induction of interleukin-7
-
Sakaguchi M, Kataoka K, Abarzua F, Tanimoto R, Watanabe M, Murata H, Than SS, Kurose K, Kashiwakura Y, Ochiai K, Nasu Y, Kumon H and Huh NH: Overexpression of REIC/Dkk-3 in normal fibroblasts suppresses tumor growth via induction of interleukin-7. J Biol Chem 284: 14236-14244, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 14236-14244
-
-
Sakaguchi, M.1
Kataoka, K.2
Abarzua, F.3
Tanimoto, R.4
Watanabe, M.5
Murata, H.6
Than, S.S.7
Kurose, K.8
Kashiwakura, Y.9
Ochiai, K.10
Nasu, Y.11
Kumon, H.12
Huh, N.H.13
-
21
-
-
78649928294
-
Expression pattern of REIC/Dkk-3 in various cell types and the implications of the soluble form in prostatic acinar development
-
Zhang K, Watanabe M, Kashiwakura Y, Li SA, Edamura K, Huang P, Yamaguchi K, Nasu Y, Kobayashi Y, Sakaguchi M, Ochiai K, Yamada H, Takei K, Ueki H, Huh NH, Li M, Kaku H, Na Y and Kumon H: Expression pattern of REIC/Dkk-3 in various cell types and the implications of the soluble form in prostatic acinar development. Int J Oncol 37: 1495-1501, 2010.
-
(2010)
Int J Oncol
, vol.37
, pp. 1495-1501
-
-
Zhang, K.1
Watanabe, M.2
Kashiwakura, Y.3
Li, S.A.4
Edamura, K.5
Huang, P.6
Yamaguchi, K.7
Nasu, Y.8
Kobayashi, Y.9
Sakaguchi, M.10
Ochiai, K.11
Yamada, H.12
Takei, K.13
Ueki, H.14
Huh, N.H.15
Li, M.16
Kaku, H.17
Na, Y.18
Kumon, H.19
-
22
-
-
80052036649
-
Tumor suppressor REIC/Dkk-3 interacts with the dynein light chain, Tctex-1
-
Ochiai K, Watanabe M, Ueki H, Huang P, Fujii Y, Nasu Y, Noguchi H, Hirata T, Sakaguchi M, Huh NH, Kashiwakura Y, Kaku H and Kumon H: Tumor suppressor REIC/Dkk-3 interacts with the dynein light chain, Tctex-1. Biochem Biophys Res Commun 412: 391-395, 2011.
-
(2011)
Biochem Biophys Res Commun
, vol.412
, pp. 391-395
-
-
Ochiai, K.1
Watanabe, M.2
Ueki, H.3
Huang, P.4
Fujii, Y.5
Nasu, Y.6
Noguchi, H.7
Hirata, T.8
Sakaguchi, M.9
Huh, N.H.10
Kashiwakura, Y.11
Kaku, H.12
Kumon, H.13
-
23
-
-
84863599949
-
REIC/Dkk-3-encoding adenoviral vector as a potentially effective therapeutic agent for bladder cancer
-
Hirata T, Watanabe M, Kaku H, Kobayashi Y, Yamada H, Sakaguchi M, Takei K, Huh NH, Nasu Y and Kumon H: REIC/Dkk-3-encoding adenoviral vector as a potentially effective therapeutic agent for bladder cancer. Int J Oncol 41: 559-564, 2012.
-
(2012)
Int J Oncol
, vol.41
, pp. 559-564
-
-
Hirata, T.1
Watanabe, M.2
Kaku, H.3
Kobayashi, Y.4
Yamada, H.5
Sakaguchi, M.6
Takei, K.7
Huh, N.H.8
Nasu, Y.9
Kumon, H.10
-
24
-
-
22544453919
-
Improved neuronal transgene expression from an AAV-2 vector with a hybrid CMV enhancer/PDGF-beta promoter
-
DOI 10.1002/jgm.742
-
Wang CY, Guo HY, Lim TM, Ng YK, Neo HP, Hwang PY, Yee WC and Wang S: Improved neuronal transgene expression from an AAV-2 vector with a hybrid CMV enhancer/PDGF-beta promoter. J Gene Med 7: 945-955, 2005. (Pubitemid 41015543)
-
(2005)
Journal of Gene Medicine
, vol.7
, Issue.7
, pp. 945-955
-
-
Wang, C.Y.1
Guo, H.Y.2
Lim, T.M.3
Ng, Y.K.4
Neo, H.P.5
Hwang, P.Y.K.6
Yee, W.-C.7
Wang, S.8
|