Nuclear trafficking of the HIV-1 pre-integration complex depends on the ADAM10 intracellular domain

Virology

Volumn 454-455, Issue 1, 2014, Pages 60-66

  Endsley, Mark A ^a   Somasunderam, Anoma D ^a   Li, Guangyu ^b   Oezguen, Numan ^c   Thiviyanathan, Varatharasa ^d   Murray, James L ^e   Rubin, Donald H ^f,g   Hodge, Thomas W ^h   O'Brien, William A ^a,i,j   Lewis, Briana ^a   Ferguson, Monique R ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b East Tennessee State University   (United States)

^c TEXAS CHILDREN S HOSPITAL   (United States)

^d UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^e GeneTAG Technology Inc   (United States)

^f VETERANS AFFAIRS MEDICAL CENTER   (United States)

^g VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h Tamir Biotechnology   (United States)

ⁱ BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

^j EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

more..

Author keywords

Secretase; ADAM10; ADAM15; CD4+ T lymphocytes; HIV 1 integrase; HIV 1 pre integration complex (PIC); HIV 1 replication; Macrophages

Indexed keywords

ADAM10 ENDOPEPTIDASE; ADAM15 PROTEIN; AVIDIN; GAMMA SECRETASE; METALLOPROTEINASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CD4+ T LYMPHOCYTE; CELL MIGRATION; CELLULAR PARAMETERS; CONTROLLED STUDY; DNA INTEGRATION; GENE DOSAGE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; INTRACELLULAR DOMAIN; NONHUMAN; PRE INTEGRATION COMPLEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; REVERSE TRANSCRIPTION; VIRUS DNA CELL DNA INTERACTION; VIRUS REPLICATION;

ADAM10; ADAM15; CD4(+) T LYMPHOCYTES; HIV-1 INTEGRASE; HIV-1 PRE-INTEGRATION COMPLEX (PIC); HIV-1 REPLICATION; MACROPHAGES; Γ-SECRETASE;

ACTIVE TRANSPORT, CELL NUCLEUS; ADAM PROTEINS; AMYLOID PRECURSOR PROTEIN SECRETASES; CELLS, CULTURED; DNA, VIRAL; HIV-1; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNOPRECIPITATION; MACROMOLECULAR SUBSTANCES; MEMBRANE PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; VIRAL PROTEINS; VIRUS INTEGRATION;

EID: 84896735482     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2014.02.006     Document Type: Article

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