Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics

Journal of Allergy and Clinical Immunology

Volumn 133, Issue 3, 2014, Pages

  Wu, Ann Chen ^a,b   Himes, Blanca E ^a,c   Lasky Su, Jessica ^a,c   Litonjua, Augusto ^a,c   Peters, Stephen P ^d   Lima, John ^e   Kubo, Michiaki ^f   Tamari, Mayumi ^f   Nakamura, Yusuke ^g   Qiu, Weiliang ^a,c   Weiss, Scott T ^a,c   Tantisira, Kelan ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d WAKE FOREST SCHOOL OF MEDICINE   (United States)

^e NEMOURS CHILDREN S CLINIC   (United States)

^f RIKEN Center for Integrative Medical Sciences   (Japan)

^g UNIVERSITY OF TOKYO   (Japan)

Author keywords

Asthma; bronchodilator response; inhaled corticosteroids; lung function; single nucleotide polymorphisms; zinc finger proteins; ZNF432

Indexed keywords

BUDESONIDE; NEDOCROMIL; ZINC FINGER PROTEIN;

ARTICLE; ASTHMA; CHILD; CHROMOSOME 19; CORTICOSTEROID THERAPY; DRUG RESPONSE; ENVIRONMENTAL EXPOSURE; FEMALE; FORCED EXPIRATORY VOLUME; GENE; GENE EXPRESSION; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; QUANTITATIVE TRAIT; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM; ZNF432 GENE;

ASTHMA; BRONCHODILATOR RESPONSE; INHALED CORTICOSTEROIDS; LUNG FUNCTION; SINGLE NUCLEOTIDE POLYMORPHISMS; ZINC FINGER PROTEINS; ZNF432;

ADMINISTRATION, INHALATION; ADOLESCENT; ADRENAL CORTEX HORMONES; ADULT; AGED; ASTHMA; BRONCHODILATOR AGENTS; FEMALE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; REGRESSION ANALYSIS; REPRESSOR PROTEINS; ZINC FINGERS;

EID: 84896732436     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2013.09.037     Document Type: Article

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