MicroRNA-99a inhibiting cell proliferation, migration and invasion by targeting fibroblast growth factor receptor 3 in bladder cancer

Oncology Letters

Volumn 7, Issue 4, 2014, Pages 1219-1224

  Wu, Deyao ^a   Zhou, Yunfeng ^a   Pan, Huixing ^a   Zhou, Jian ^a   Fan, Yuanfeng ^a   Qu, Ping ^a  

^a NANTONG MEDICAL COLLEGE   (China)

Author keywords

Bladder cancer; Fibroblast growth factor receptor 3; MicroRNA; MiR 99a

Indexed keywords

FIBROBLAST GROWTH FACTOR 3; MICRORNA; MICRORNA 99A; UNCLASSIFIED DRUG;

ARTICLE; BLADDER CANCER; CANCER INHIBITION; CELL GROWTH; CELL INVASION; CELL INVASION ASSAY; CELL MIGRATION; CELL MIGRATION ASSAY; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LUCIFERASE ASSAY; WESTERN BLOTTING;

EID: 84896730942     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2014.1875     Document Type: Article

References (27)

1. Chen X, Wang T, Yang D, Wang J, Li X, He Z, Chen F, Che X and Song X: Expression of the IAP protein family acts cooperatively to predict prognosis in human bladder cancer patients. Oncol Lett 5: 1278-1284, 2013.
2. Jemal A, Siegel R, Xu J and Ward E: Cancer statistics, 2010. CA Cancer J Clin 60: 277-300, 2010.
3. Chen MF, Lin PY, Wu CF, Chen WC and Wu CT: IL-6 expression regulates tumorigenicity and correlates with prognosis in bladder cancer. PloS One 8: e61901, 2013.
4. Dip N, Reis ST, Srougi M, Dall'Oglio MF and Leite KR: Expression profile of microrna-145 in urothelial bladder cancer. Int Braz J Urol 39: 95-102, 2013.
5. Wang T, Li M, Guan J, Li P, Wang H, Guo Y, Shuai S and Li X: MicroRNAs miR-27a and miR-143 regulate porcine adipocyte lipid metabolism. Int J Mol Sci 12: 7950-7959, 2011.
6. Xu B, Niu X, Zhang X, Tao J, Wu D, Wang Z, Li P, Zhang W, Wu H, Feng N, et al: miR-143 decreases prostate cancer cells proliferation and migration and enhances their sensitivity to docetaxel through suppression of KRAS. Mol Cell Biochem 350: 207-213, 2011.
7. Iorio MV and Croce CM: MicroRNAs in cancer: small molecules with a huge impact. J Clin Oncol 27: 5848-5856, 2009.
8. Kurokawa R: Long noncoding RNA as a regulator for transcription. Prog Mol Subcell Biol 51: 29-41, 2011.
9. Liu CG, Calin GA, Meloon B, Gamliel N, Sevignani C, Ferracin M, Dumitru CD, Shimizu M, Zupo S, Dono M, et al: An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues. Proc Natl Acad Sci USA 101: 9740-9744, 2004.
10. Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, Petrocca F, Visone R, Iorio M, Roldo C, Ferracin M, et al: A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 103: 2257-2261, 2006.
11. Cui L, Zhou H, Zhao H, Zhou Y, Xu R, Xu X, Zheng L, Xue Z, Xia W, Zhang B, et al: MicroRNA-99a induces G1-phase cell cycle arrest and suppresses tumorigenicity in renal cell carcinoma. BMC Cancer 12: 546, 2012.
12. Jemal A, Siegel R, Ward E, Murray T, Xu J and Thun MJ: Cancer statistics, 2007. CA Cancer J Clin 57: 43-66, 2007.
13. Nagayama K, Kohno T, Sato M, Arai Y, Minna JD and Yokota J: Homozygous deletion scanning of the lung cancer genome at a 100-kb resolution. Genes Chromosomes Cancer 46: 1000-1010, 2007.
14. Li D, Liu X, Lin L, Hou J, Li N, Wang C, Wang P, Zhang Q, Zhang P, Zhou W, et al: MicroRNA-99a inhibits hepatocellular carcinoma growth and correlates with prognosis of patients with hepatocellular carcinoma. J Biol Chem 286: 36677-36685, 2011.
15. di Martino E, Tomlinson DC and Knowles MA: A Decade of FGF receptor research in bladder cancer: past, present, and future challenges. Adv Urol 2012: 429213, 2012.
16. Billerey C, Chopin D, Aubriot-Lorton MH, Ricol D, Gil Diez de Medina S, Van Rhijn B, Bralet MP, Lefrere-Belda MA, Lahaye JB, Abbou CC, et al: Frequent FGFR3 mutations in papillary non-invasive bladder (pTa) tumors. Am J Pathol 158: 1955-1959, 2001.
17. Cappellen D, De Oliveira C, Ricol D, de Medina S, Bourdin J, Sastre-Garau X, Chopin D, Thiery JP and Radvanyi F: Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas. Nat Genet 23: 18-20, 1999.
18. Haugsten EM, Wiedlocha A, Olsnes S and Wesche J: Roles of fibroblast growth factor receptors in carcinogenesis. Mol Cancer Res 8: 1439-1452, 2010.
19. Iyer G and Milowsky MI: Fibroblast growth factor receptor-3 in urothelial tumorigenesis. Urol Oncol 31: 303-311, 2013.
20. Sonvilla G, Allerstorfer S, Heinzle C, Stattner S, Karner J, Klimpfinger M, Wrba F, Fischer H, Gauglhofer C, Spiegl-Kreinecker S, et al: Fibroblast growth factor receptor 3-IIIc mediates colorectal cancer growth and migration. Br J Cancer 102: 1145-1156, 2010.
21. Miyake M, Sugano K, Sugino H, Imai K, Matsumoto E, Maeda K, Fukuzono S, Ichikawa H, Kawashima K, Hirabayashi K, et al: Fibroblast growth factor receptor 3 mutation in voided urine is a useful diagnostic marker and significant indicator of tumor recurrence in non-muscle invasive bladder cancer. Cancer Sci 101: 250-258, 2010.
22. Henson BJ and Gollin SM: Overexpression of KLF13 and FGFR3 in oral cancer cells. Cytogenet Genome Res 128: 192-198, 2010.
23. Tomlinson DC, Hurst CD and Knowles MA: Knockdown by shRNA identifies S249C mutant FGFR3 as a potential therapeutic target in bladder cancer. Oncogene 26: 5889-5899, 2007.
24. Matsumoto M, Ohtsuki Y, Ochii K, Seike Y, Iseda N, Sasaki T, Okada Y, Kurabayashi A and Furihata M: Fibroblast growth factor receptor 3 protein expression in urothelial carcinoma of the urinary bladder, exhibiting no association with low-grade and/or non-invasive lesions. Oncol Rep 12: 967-971, 2004.
25. Mhawech-Fauceglia P, Cheney RT, Fischer G, Beck A and Herrmann FR: FGFR3 and p53 protein expressions in patients with pTa and pT1 urothelial bladder cancer. Eur J Surg Oncol 32: 231-237, 2006.
26. Gómez-Román JJ, Saenz P, Molina M, Cuevas González J, Escuredo K, Santa Cruz S, Junquera C, Simón L, Martínez A, Gutiérrez Baños JL, et al: Fibroblast growth factor receptor 3 is overexpressed in urinary tract carcinomas and modulates the neoplastic cell growth. Clin Cancer Res 11: 459-465, 2005.
27. Tomlinson DC, Baldo O, Harnden P and Knowles MA: FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer. J Pathol 213: 91-98, 2007.