The impact of sustained and intermittent docetaxel chemotherapy regimens on cognition and neural morphology in healthy mice

Psychopharmacology

Volumn 231, Issue 5, 2014, Pages 841-852

  Fardell, Joanna E ^b   Zhang, Ji ^a   De Souza, Raquel ^a   Vardy, Janette ^c   Johnston, Ian ^b   Allen, Christine ^a   Henderson, Jeffrey ^a   Piquette Miller, Micheline ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF SYDNEY   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Autophagy; Chemobrain; Chemotherapy; Cognition; Docetaxel; Memory; Mice

Indexed keywords

CASPASE 3; DOCETAXEL; GLIAL FIBRILLARY ACIDIC PROTEIN; MICROTUBULE ASSOCIATED PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN 1 LIGHT CHAIN 3; MULTIDRUG RESISTANCE PROTEIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; DELAYED RELEASE FORMULATION; TAXOID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; AUTOPHAGY; CANCER CHEMOTHERAPY; CD-1 MOUSE; COGNITIVE DEFECT; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG INTERMITTENT THERAPY; MALE; MORRIS WATER MAZE TEST; MOUSE; NEUROTOXICITY; NONHUMAN; NOVEL OBJECT RECOGNITION TEST; PRIORITY JOURNAL; WEIGHT GAIN; ANIMAL; ANIMAL BEHAVIOR; BIOSYNTHESIS; BLOOD; BODY WEIGHT; BRAIN; CHEMICALLY INDUCED; COGNITION; CYTOLOGY; DELAYED RELEASE FORMULATION; DRUG ADMINISTRATION; DRUG EFFECTS; METABOLISM; PATHOLOGY; TOXICITY;

ANIMALS; ANTINEOPLASTIC AGENTS; ASTROCYTES; AUTOPHAGY; BEHAVIOR, ANIMAL; BODY WEIGHT; BRAIN; COGNITION; COGNITION DISORDERS; DELAYED-ACTION PREPARATIONS; DRUG ADMINISTRATION SCHEDULE; MALE; MICE; P-GLYCOPROTEIN; TAXOIDS;

EID: 84896723125     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-013-3301-8     Document Type: Article

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