High Risk Population Isolate Reveals Low Frequency Variants Predisposing to Intracranial Aneurysms

PLoS Genetics

Volumn 10, Issue 1, 2014, Pages

  Kurki, Mitja I ^a,b   Gaál, Emília Ilona ^c   Kettunen, Johannes ^d,e   Lappalainen, Tuuli ^f   Menelaou, Androniki ^g   Anttila, Verneri ^d,h,i   van 't Hof, Femke N G ^g   von und zu Fraunberg, Mikael ^a,b   Helisalmi, Seppo ^b   Hiltunen, Mikko ^b   Lehto, Hanna ^c   Laakso, Aki ^c   Kivisaari, Riku ^c   Koivisto, Timo ^a   Ronkainen, Antti ^a   Rinne, Jaakko ^a   Kiemeney, Lambertus A L ^j   Vermeulen, Sita H ^j   Kaunisto, Mari A ^d,k   Eriksson, Johan G ^c,d,e,k,l   Aromaa, Arpo ^e   Perola, Markus ^d,e,m   Lehtimäki, Terho ⁿ   Raitakari, Olli T ^o,p   Salomaa, Veikko ^e   Gunel, Murat ^q   Dermitzakis, Emmanouil T ^f   Ruigrok, Ynte M ^g   Rinkel, Gabriel J E ^g   Niemelä, Mika ^c   Hernesniemi, Juha ^c   Ripatti, Samuli ^d,e   de Bakker, Paul I W ^g,i,r   Palotie, Aarno ^d,h,i,s   Jääskeläinen, Juha E ^a,b   more..

^a KUOPIO UNIVERSITY HOSPITAL   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^d UNIVERSITY OF HELSINKI   (Finland)

^e NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^f UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^g UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^h MASSACHUSETTS GENERAL HOSPITAL   (United States)

ⁱ BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^j RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^k FOLKHÄLSAN RESEARCH CENTER   (Finland)

^l VAASA CENTRAL HOSPITAL   (Finland)

^m UNIVERSITY OF TARTU   (Estonia)

ⁿ TAMPERE UNIVERSITY HOSPITAL   (Finland)

^o UNIVERSITY OF TURKU   (Finland)

^p UNIVERSITY OF TURKU   (Finland)

^q HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^r BRIGHAM AND WOMEN S HOSPITAL   (United States)

^s WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ALLELE; ANKRD44 GENE; ARTICLE; CASE CONTROL STUDY; CDKN2B AS1 GENE; CHROMOSOME 2Q; CHROMOSOME 5Q; CHROMOSOME 6Q; CHROMOSOME 7P; CHROMOSOME 9P; COHORT ANALYSIS; CONTROLLED STUDY; DUTCH; EFFECT SIZE; EPM2A GENE; ETHNIC DIFFERENCE; ETHNIC GROUP; EUROPEAN; FEMALE; FINLAND; FINNISH; FSTL1 GENE; FSTL4 GENE; GENE; GENE FREQUENCY; GENE LOCUS; GENE MAPPING; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETIC VARIABILITY; GENOTYPE; HERITABILITY; HIGH RISK POPULATION; HUMAN; INCIDENCE; INTRACRANIAL ANEURYSM; LYPD6 GENE; MAJOR CLINICAL STUDY; MALE; MMADHC GENE; NETHERLANDS; PATHOGENESIS; PHENOTYPE; QUANTITATIVE TRAIT LOCUS; SACCULAR ANEURYSM; SINGLE NUCLEOTIDE POLYMORPHISM; TLR4 GENE;

CHROMOSOMES, HUMAN, PAIR 2; EUROPE; FINLAND; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENETICS, POPULATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; INTRACRANIAL ANEURYSM; RISK FACTORS; STROKE; SUBARACHNOID HEMORRHAGE;

EID: 84896718035     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004134     Document Type: Article

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