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Volumn 31, Issue 3, 2014, Pages 1407-1416

Differential effects of erufosine on proliferation, wound healing and apoptosis in colorectal cancer cell lines

Author keywords

Collagen; Colorectal cancer cell lines; Erufosine; Osteonectin; Wound healing

Indexed keywords

ANTIMITOTIC AGENT; CASPASE 3; CASPASE 7; ERUFOSINE; OSTEONECTIN; UNCLASSIFIED DRUG;

EID: 84896717524     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2013.2942     Document Type: Article
Times cited : (18)

References (59)
  • 1
    • 84871036375 scopus 로고    scopus 로고
    • Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the Global Burden of Disease Study 2010
    • Lozano R, Naghavi M, Foreman K, et al: Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 380: 2095-2128, 2012.
    • (2012) Lancet , vol.380 , pp. 2095-2128
    • Lozano, R.1    Naghavi, M.2    Foreman, K.3
  • 3
    • 0034729931 scopus 로고    scopus 로고
    • Relation between tumour response to first-line chemotherapy and survival in advanced colorectal cancer: A meta-analysis
    • Buyse M, Thirion P, Carlson RW, Burzykowski T, Molenberghs G and Piedbois P: Relation between tumour response to first-line chemotherapy and survival in advanced colorectal cancer: a meta-analysis. Lancet 356: 373-378, 2000. (Pubitemid 30487493)
    • (2000) Lancet , vol.356 , Issue.9227 , pp. 373-378
    • Buyse, M.1    Thirion, P.2    Carlson, R.W.3    Burzykowski, T.4    Molenberghs, G.5    Piedbois, P.6
  • 6
    • 36048960109 scopus 로고    scopus 로고
    • Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: Results from the BICC-C Study
    • Fuchs CS, Marshall J, Mitchell E, et al: Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: results from the BICC-C Study. J Clin Oncol 25: 4779-4786, 2007.
    • (2007) J Clin Oncol , vol.25 , pp. 4779-4786
    • Fuchs, C.S.1    Marshall, J.2    Mitchell, E.3
  • 7
    • 0033874892 scopus 로고    scopus 로고
    • Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
    • de Gramont A, Figer A, Seymour M, et al : Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol 18: 2938-2947, 2000.
    • (2000) J Clin Oncol , vol.18 , pp. 2938-2947
    • De Gramont, A.1    Figer, A.2    Seymour, M.3
  • 8
    • 0034727063 scopus 로고    scopus 로고
    • Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer
    • Saltz LB, Cox JV, Blanke C, et al: Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. N Engl J Med 343: 905-914, 2000.
    • (2000) N Engl J Med , vol.343 , pp. 905-914
    • Saltz, L.B.1    Cox, J.V.2    Blanke, C.3
  • 11
    • 59749091477 scopus 로고    scopus 로고
    • Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer
    • Tol J, Koopman M, Cats A, et al: Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer. N Engl J Med 360: 563-572, 2009.
    • (2009) N Engl J Med , vol.360 , pp. 563-572
    • Tol, J.1    Koopman, M.2    Cats, A.3
  • 13
    • 84883381780 scopus 로고    scopus 로고
    • Bevacizumab plus chemotherapy continued beyond first progression in patients with metastatic colorectal cancer previously treated with bevacizumab plus chemotherapy: ML18147 study KRAS subgroup findings
    • Kubicka S, Greil R, André T, et al: Bevacizumab plus chemotherapy continued beyond first progression in patients with metastatic colorectal cancer previously treated with bevacizumab plus chemotherapy: ML18147 study KRAS subgroup findings. Ann Oncol 24: 2342-2349, 2013.
    • (2013) Ann Oncol , vol.24 , pp. 2342-2349
    • Kubicka, S.1    Greil, R.2    André, T.3
  • 14
    • 84867047384 scopus 로고    scopus 로고
    • Addition of aflibercept to fluorouracil, leucovorin, and irinotecan improves survival in a phase III randomized trial in patients with metastatic colorectal cancer previously treated with an oxaliplatin-based regimen
    • Van Cutsem E, Tabernero J, Lakomy R, et al: Addition of aflibercept to fluorouracil, leucovorin, and irinotecan improves survival in a phase III randomized trial in patients with metastatic colorectal cancer previously treated with an oxaliplatin-based regimen. J Clin Oncol 30: 3499-3506, 2012.
    • (2012) J Clin Oncol , vol.30 , pp. 3499-3506
    • Van Cutsem, E.1    Tabernero, J.2    Lakomy, R.3
  • 15
    • 42949149159 scopus 로고    scopus 로고
    • Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: A randomized phase III study
    • Saltz LB, Clarke S, Díaz-Rubio E, et al: Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. J Clin Oncol 26: 2013-2019, 2008.
    • (2008) J Clin Oncol , vol.26 , pp. 2013-2019
    • Saltz, L.B.1    Clarke, S.2    Díaz-Rubio, E.3
  • 17
    • 0032189615 scopus 로고    scopus 로고
    • Cytotoxic ether-phospholipid analogues
    • Berkovic D: Cytotoxic ether-phospholipid analogues. Gen Pharmacol 31: 511-517, 1998.
    • (1998) Gen Pharmacol , vol.31 , pp. 511-517
    • Berkovic, D.1
  • 18
    • 33847289770 scopus 로고    scopus 로고
    • Rationale and clinical application of alkylphospholipid analogues in combination with radiotherapy
    • DOI 10.1016/j.ctrv.2006.12.001, PII S0305737206002386
    • Vink SR, van Blitterswijk WJ, Schellens JHM and Verheij M: Rationale and clinical application of alkylphospholipid analogues in combination with radiotherapy. Cancer Treat Rev 33: 191-202, 2007. (Pubitemid 46323398)
    • (2007) Cancer Treatment Reviews , vol.33 , Issue.2 , pp. 191-202
    • Vink, S.R.1    Van Blitterswijk, W.J.2    Schellens, J.H.M.3    Verheij, M.4
  • 19
    • 84873163534 scopus 로고    scopus 로고
    • Anticancer mechanisms and clinical application of alkylphospholipids
    • Van Blitterswijk WJ and Verheij M: Anticancer mechanisms and clinical application of alkylphospholipids. Biochim Biophys Acta 1831: 663-674, 2013.
    • (2013) Biochim Biophys Acta , vol.1831 , pp. 663-674
    • Van Blitterswijk, W.J.1    Verheij, M.2
  • 21
    • 0037190119 scopus 로고    scopus 로고
    • Combination effects of alkylphosphocholines and gemcitabine in malignant and normal hematopoietic cells
    • DOI 10.1016/S0304-3835(02)00088-5, PII S0304383502000885
    • Georgieva MC, Konstantinov SM, Topashka-Ancheva M and Berger MR: Combination effects of alkylphosphocholines and gemcitabine in malignant and normal hematopoietic cells. Cancer Lett 182: 163-174, 2002. (Pubitemid 34621180)
    • (2002) Cancer Letters , vol.182 , Issue.2 , pp. 163-174
    • Georgieva, M.C.1    Konstantinov, S.M.2    Topashka-Ancheva, M.3    Berger, M.R.4
  • 22
    • 82455175173 scopus 로고    scopus 로고
    • Erufosine, an alkylphosphocholine, with differential toxicity to human cancer cells and bone marrow cells
    • Bagley RG, Kurtzberg L, Rouleau C, Yao M and Teicher BA: Erufosine, an alkylphosphocholine, with differential toxicity to human cancer cells and bone marrow cells. Cancer Chemother Pharmacol 68: 1537-1546, 2011.
    • (2011) Cancer Chemother Pharmacol , vol.68 , pp. 1537-1546
    • Bagley, R.G.1    Kurtzberg, L.2    Rouleau, C.3    Yao, M.4    Teicher, B.A.5
  • 23
    • 34247859084 scopus 로고    scopus 로고
    • Erufosine: A membrane targeting antineoplastic agent with signal transduction modulating effects
    • DOI 10.1196/annals.1397.022, Signal Transduction Pathways, Part C: Cell Signaling in Health and Disease
    • Zaharieva MM, Konstantinov SM, Pilicheva B, Karaivanova M and Berger MR: Erufosine - a membrane targeting antineoplastic agent with signal transduction modulating effects. Ann NY Acad Sci 1095: 182-192, 2007. (Pubitemid 47092450)
    • (2007) Annals of the New York Academy of Sciences , vol.1095 , pp. 182-192
    • Zaharieva, M.M.1    Konstantinov, S.M.2    Pilicheva, B.3    Karaivanova, M.4    Berger, M.R.5
  • 24
    • 43749088540 scopus 로고    scopus 로고
    • Erufosine, a novel alkylphosphocholine, in acute myeloid leukemia: Single activity and combination with other antileukemic drugs
    • DOI 10.1007/s00280-007-0612-7
    • Fiegl M, Lindner LH, Juergens M, Eibl H, Hiddemann W and Braess J: Erufosine, a novel alkylphosphocholine, in acute myeloid leukemia: single activity and combination with other antileukemic drugs. Cancer Chemother Pharmacol 62: 321-329, 2008. (Pubitemid 351692092)
    • (2008) Cancer Chemotherapy and Pharmacology , vol.62 , Issue.2 , pp. 321-329
    • Fiegl, M.1    Lindner, L.H.2    Juergens, M.3    Eibl, H.4    Hiddemann, W.5    Braess, J.6
  • 25
    • 77950937717 scopus 로고    scopus 로고
    • Erucylphosphohomocholine, the first intravenously applicable alkylphosphocholine, is cytotoxic to acute myelogenous leukemia cells through JNK- and PP2A-dependent mechanisms
    • Martelli AM, Papa V, Tazzari PL, et al: Erucylphosphohomocholine, the first intravenously applicable alkylphosphocholine, is cytotoxic to acute myelogenous leukemia cells through JNK- and PP2A-dependent mechanisms. Leukemia 24: 687-698, 2010.
    • (2010) Leukemia , vol.24 , pp. 687-698
    • Martelli, A.M.1    Papa, V.2    Tazzari, P.L.3
  • 26
    • 77953613405 scopus 로고    scopus 로고
    • Erufosine, a novel alkylphosphocholine, induces apoptosis in CLL through a caspase-dependent pathway
    • Königs SK, Pallascha CP, Lindnerb LH, et al: Erufosine, a novel alkylphosphocholine, induces apoptosis in CLL through a caspase-dependent pathway. Leuk Res 34: 1064-1069, 2010.
    • (2010) Leuk Res , vol.34 , pp. 1064-1069
    • Königs, S.K.1    Pallascha, C.P.2    Lindnerb, L.H.3
  • 27
    • 84859842055 scopus 로고    scopus 로고
    • Interleukin-6, osteopontin and Raf/MEK/ERK signaling modulate the sensitivity of human myeloma cells to alkylphosphocholines
    • Yosifov DY, Reufsteck C, Konstantinov SM and Berger MR: Interleukin-6, osteopontin and Raf/MEK/ERK signaling modulate the sensitivity of human myeloma cells to alkylphosphocholines. Leuk Res 36: 764-772, 2012.
    • (2012) Leuk Res , vol.36 , pp. 764-772
    • Yosifov, D.Y.1    Reufsteck, C.2    Konstantinov, S.M.3    Berger, M.R.4
  • 28
    • 0032836892 scopus 로고    scopus 로고
    • Human urinary bladder carcinoma cell lines respond to treatment with alkylphosphocholines
    • DOI 10.1016/S0304-3835(99)00219-0, PII S0304383599002190
    • Konstantinov SM and Berger MR: Human urinary bladder carcinoma cell lines respond to treatment with alkylphosphocholines. Cancer Lett 144: 153-160, 1999. (Pubitemid 29457657)
    • (1999) Cancer Letters , vol.144 , Issue.2 , pp. 153-160
    • Konstantinov, S.M.1    Berger, M.R.2
  • 29
    • 84870426243 scopus 로고    scopus 로고
    • Erufosine suppresses breast cancer in vitro and in vivo for its activity on PI3K, c-Raf and Akt proteins
    • Dineva IK, Zaharieva MM, Konstantinov SM, Eibl H and Berger MR: Erufosine suppresses breast cancer in vitro and in vivo for its activity on PI3K, c-Raf and Akt proteins. J Cancer Res Clin Oncol 138: 1909-1917, 2012.
    • (2012) J Cancer Res Clin Oncol , vol.138 , pp. 1909-1917
    • Dineva, I.K.1    Zaharieva, M.M.2    Konstantinov, S.M.3    Eibl, H.4    Berger, M.R.5
  • 30
    • 84858074187 scopus 로고    scopus 로고
    • Erufosine simultaneously induces apoptosis and autophagy by modulating the Akt-mTOR signaling pathway in oral squamous cell carcinoma
    • Kapoor V, Zaharieva MM, Das SN and Berger MR: Erufosine simultaneously induces apoptosis and autophagy by modulating the Akt-mTOR signaling pathway in oral squamous cell carcinoma. Cancer Lett 319: 39-48, 2012.
    • (2012) Cancer Lett , vol.319 , pp. 39-48
    • Kapoor, V.1    Zaharieva, M.M.2    Das, S.N.3    Berger, M.R.4
  • 31
    • 38049101138 scopus 로고    scopus 로고
    • Synergistic inhibition of mitochondrial respiration by anticancer agent erucylphosphohomocholine and cyclosporin A
    • Lemeshko VV and Kugler W: Synergistic inhibition of mitochondrial respiration by anticancer agent erucylphosphohomocholine and cyclosporin A. J Biol Chem 282: 37303-37307, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 37303-37307
    • Lemeshko, V.V.1    Kugler, W.2
  • 32
    • 34248400321 scopus 로고    scopus 로고
    • The membrane targeted apoptosis modulators erucylphosphocholine and erucylphosphohomocholine increase the radiation response of human glioblastoma cell lines in vitro
    • Rübel A, Handrick R, Lindner LH, et al: The membrane targeted apoptosis modulators erucylphosphocholine and erucylphosphohomocholine increase the radiation response of human glioblastoma cell lines in vitro. Radiat Oncol 1: 6, 2006.
    • (2006) Radiat Oncol , vol.1 , pp. 6
    • Rübel, A.1    Handrick, R.2    Lindner, L.H.3
  • 33
    • 77954590068 scopus 로고    scopus 로고
    • Potential involvement of F0F1-ATP(synth)ase and reactive oxygen species in apoptosis induction by the antineoplastic agent erucylphosphohomocholine in glioblastoma cell lines: A mechanism for induction of apoptosis via the 18 kDa mitochondrial translocator protein
    • Veenman L, Alten J, Linnemannstöns K, et al: Potential involvement of F0F1-ATP(synth)ase and reactive oxygen species in apoptosis induction by the antineoplastic agent erucylphosphohomocholine in glioblastoma cell lines: a mechanism for induction of apoptosis via the 18 kDa mitochondrial translocator protein. Apoptosis 15: 753-768, 2010.
    • (2010) Apoptosis , vol.15 , pp. 753-768
    • Veenman, L.1    Alten, J.2    Linnemannstöns, K.3
  • 34
    • 78149493021 scopus 로고    scopus 로고
    • The Akt-inhibitor erufosine induces apoptotic cell death in prostate cancer cells and increases the short term effects of ionizing radiation
    • Rudner J, Ruiner CE, Handrick R, Eibl HJ, Belka C and Jendrossek V: The Akt-inhibitor erufosine induces apoptotic cell death in prostate cancer cells and increases the short term effects of ionizing radiation. Radiat Oncol 5: 108, 2010.
    • (2010) Radiat Oncol , vol.5 , pp. 108
    • Rudner, J.1    Ruiner, C.E.2    Handrick, R.3    Eibl, H.J.4    Belka, C.5    Jendrossek, V.6
  • 35
    • 1342284279 scopus 로고    scopus 로고
    • Induction of Apoptosis by Erucylphospho-N,N,N-trimethylammonium Is Associated with Changes in Signal Molecule Expression and Location
    • DOI 10.1196/annals.1299.054
    • Berger MR, Tsoneva I, Konstantinov SM and Eibl H: Induction of apoptosis by erucylphospho-N,N, N-trimethylammonium is associated with changes in signal molecule expression and location. Ann NY Acad Sci 1010: 307-310, 2003. (Pubitemid 38264995)
    • (2003) Annals of the New York Academy of Sciences , vol.1010 , pp. 307-310
    • Berger, M.R.1    Tsoneva, I.2    Konstantinov, S.M.3    Eibl, H.4
  • 36
    • 0026694031 scopus 로고
    • Assessment of antineoplastic agents by MTT assay: Partial underestimation of antiproliferative properties
    • Sobottka SB and Berger MR: Assessment of antineoplastic agents by MTT assay: partial underestimation of antiproliferative properties. Cancer Chemother Pharmacol 30: 385-393, 1992.
    • (1992) Cancer Chemother Pharmacol , vol.30 , pp. 385-393
    • Sobottka, S.B.1    Berger, M.R.2
  • 37
    • 0027468561 scopus 로고
    • Structure-activity relationships of four anti-cancer alkylphosphocholine derivatives in vitro and in vivo
    • DOI 10.1002/ijc.2910530312
    • Sobottka SB, Berger MR and Eibl H: Structure-activity relationships of four anti-cancer alkylphosphocholine derivatives in vitro and in vivo. Int J Cancer 53: 418-425, 1993. (Pubitemid 23047889)
    • (1993) International Journal of Cancer , vol.53 , Issue.3 , pp. 418-425
    • Sobottka, S.B.1    Berger, M.R.2    Eibl, H.3
  • 38
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T: Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65: 55-63, 1983.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 39
    • 34347218991 scopus 로고    scopus 로고
    • In vitro scratch assay: A convenient and inexpensive method for analysis of cell migration in vitro
    • DOI 10.1038/nprot.2007.30, PII NPROT.2006.30
    • Liang CC, Park AY and Guan JL: In vitro scratch assay: a convenient and inexpensive method or analysis of cell migration in vitro. Nat Protoc 2: 329-333, 2007. (Pubitemid 47040047)
    • (2007) Nature Protocols , vol.2 , Issue.2 , pp. 329-333
    • Liang, C.-C.1    Park, A.Y.2    Guan, J.-L.3
  • 40
    • 1842685155 scopus 로고    scopus 로고
    • Immunohistochemical detection of melphalan-DNA adducts in colon cancer cells in vitro and human colorectal liver tumours in vivo
    • DOI 10.1016/j.bcp.2003.12.038, PII S0006295204000383
    • Rothbarth J, Koevoets C, Tollenaar RA, Tilby MJ, van de Velde CJ, Mulder, GJ and Kuppen PJ: Immunohistochemical detection of melphalan-DNA adducts in colon cancer cells in vitro and human colorectal liver tumours in vivo. Biochem Pharmacol 67: 1771-1778, 2004. (Pubitemid 38479855)
    • (2004) Biochemical Pharmacology , vol.67 , Issue.9 , pp. 1771-1778
    • Rothbarth, J.1    Koevoets, C.2    Tollenaar, R.A.E.M.3    Tilby, M.J.4    Van De, V.C.J.H.5    Mulder, G.J.6    Kuppen, P.J.K.7
  • 41
    • 0021268794 scopus 로고
    • The DNA damage-repair hypothesis in radiation biology: Comparison with classical hit theory
    • Haynes RH, Eckardt F and Kunz BA: The DNA damage-repair hypothesis in radiation biology: comparison with classical hit theory. Br J Cancer 49: 81-90, 1984. (Pubitemid 14130898)
    • (1984) British Journal of Cancer , vol.49 , Issue.SUPPL. 6 , pp. 81-90
    • Haynes, R.H.1    Eckardt, F.2    Kunz, B.A.3
  • 42
    • 0021252983 scopus 로고
    • Concepts, problems and the role of modifying agents in the relationship between recovery of cells' survival ability and mechanisms of repair of radiation lesions
    • Orr JS: Concepts, problems and the role of modifying agents in the relationship between recovery of cells' survival ability and mechanisms of repair of radiation lesions. Br J Cancer (Suppl) 49: 1-6, 1984.
    • (1984) Br J Cancer , vol.49 , Issue.SUPPL. , pp. 1-6
    • Orr, J.S.1
  • 43
    • 84896729418 scopus 로고    scopus 로고
    • Radiobiology of low- and high-dose-rate brachytherapy
    • 4th edition. Levitt SH, Purdy JA, Perez CA and Vijayakumar S (eds). Springer Verlag, Berlin
    • Hall EJ and Brenner DJ: Radiobiology of low- and high-dose-rate brachytherapy. In: Technical Basis of Radiation Therapy. 4th edition. Levitt SH, Purdy JA, Perez CA and Vijayakumar S (eds). Springer Verlag, Berlin, pp291-307, 2008.
    • (2008) Technical Basis of Radiation Therapy , pp. 291-307
    • Hall, E.J.1    Brenner, D.J.2
  • 44
    • 79951655008 scopus 로고    scopus 로고
    • Inhibitor of apoptosis protein family as diagnostic markers and therapeutic targets of colorectal cancer
    • Miura K, Fujibuchi W, Ishida K, et al: Inhibitor of apoptosis protein family as diagnostic markers and therapeutic targets of colorectal cancer. Surg Today 41: 175-182, 2011.
    • (2011) Surg Today , vol.41 , pp. 175-182
    • Miura, K.1    Fujibuchi, W.2    Ishida, K.3
  • 45
    • 79959917001 scopus 로고    scopus 로고
    • The insulin-like growth factor binding proteins 3 and 7 are associated with colorectal cancer and liver metastasis
    • Georges RB, Adwan H, Hamdi H, Hielscher T, Linnemann U and Berger MR: The insulin-like growth factor binding proteins 3 and 7 are associated with colorectal cancer and liver metastasis. Cancer Biol Ther 12: 69-79, 2011.
    • (2011) Cancer Biol Ther , vol.12 , pp. 69-79
    • Georges, R.B.1    Adwan, H.2    Hamdi, H.3    Hielscher, T.4    Linnemann, U.5    Berger, M.R.6
  • 46
    • 84865502454 scopus 로고    scopus 로고
    • CXCL5, a promoter of cell proliferation, migration and invasion, is a novel serum prognostic marker in patients with colorectal cancer
    • Kawamura M, Toiyama Y, Tanaka K, et al: CXCL5, a promoter of cell proliferation, migration and invasion, is a novel serum prognostic marker in patients with colorectal cancer. Eur J Cancer 48: 2244-2251, 2012.
    • (2012) Eur J Cancer , vol.48 , pp. 2244-2251
    • Kawamura, M.1    Toiyama, Y.2    Tanaka, K.3
  • 47
    • 67650563916 scopus 로고    scopus 로고
    • SirT1 is an inhibitor of proliferation and tumor formation in colon cancer
    • Kabra N, Li Z, Chen L, et al: SirT1 is an inhibitor of proliferation and tumor formation in colon cancer. J Biol Chem 284: 18210-18217, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 18210-18217
    • Kabra, N.1    Li, Z.2    Chen, L.3
  • 48
    • 42449105737 scopus 로고    scopus 로고
    • The expression level of the tumor suppressor retinoblastoma protein (Rb) influences the antileukemic efficacy of erucylphospho-N,N,N- trimethylpropylammonium (ErPC3)
    • Yosifov DY, Dineva IK, Zaharieva MM, Konstantinov SM and Berger MR: The expression level of the tumor suppressor retinoblastoma protein (Rb) influences the antileukemic efficacy of erucylphospho-N,N,N-trimethylpropylammonium (ErPC3). Cancer Biol Ther 6: 930-935, 2007. (Pubitemid 351574984)
    • (2007) Cancer Biology and Therapy , vol.6 , Issue.6 , pp. 930-935
    • Yosifov, D.Y.1    Dineva, I.K.2    Zaharieva, M.M.3    Konstantinov, S.M.4    Berger, M.R.5
  • 49
    • 4444306013 scopus 로고    scopus 로고
    • The Rb network
    • DeGregori J: The Rb network. J Cell Sci 117: 3411-3413, 2004.
    • (2004) J Cell Sci , vol.117 , pp. 3411-3413
    • DeGregori, J.1
  • 50
    • 24644483620 scopus 로고    scopus 로고
    • Downregulation of Apaf-1 and caspase-3 by RNA interference in human glioma cells: Consequences for erucylphosphocholine-induced apoptosis
    • DOI 10.1007/s10495-005-1190-y
    • Kugler W, Buchholz F, Köhler F, Eibl H, Lakomek M and Erdlenbruch B: Downregulation of Apaf-1 and caspase-3 by RNA interference in human glioma cells: consequences for erucylphosphocholine-induced apoptosis. Apoptosis 10: 1163-1174, 2005. (Pubitemid 41285591)
    • (2005) Apoptosis , vol.10 , Issue.5 , pp. 1163-1174
    • Kugler, W.1    Buchholz, F.2    Kohler, F.3    Eibl, H.4    Lakomek, M.5    Erdlenbruch, B.6
  • 51
    • 67651100825 scopus 로고    scopus 로고
    • IGF-I activates caspases 3/7, 8 and 9 but does not induce cell death in colorectal cancer cells
    • Yang SY, Bolvin C, Sales KM, Fuller B, Seifalian AM and Winslet MC: IGF-I activates caspases 3/7, 8 and 9 but does not induce cell death in colorectal cancer cells. BMC Cancer 9: 158, 2009.
    • (2009) BMC Cancer , vol.9 , pp. 158
    • Yang, S.Y.1    Bolvin, C.2    Sales, K.M.3    Fuller, B.4    Seifalian, A.M.5    Winslet, M.C.6
  • 52
    • 33748793685 scopus 로고    scopus 로고
    • Physiological functions of caspases beyond cell death
    • DOI 10.2353/ajpath.2006.060105
    • Nhan TQ, Liles WC and Schwartz SM: Physiological functions of caspases beyond cell death. Am J Pathol 169: 729-737, 2006. (Pubitemid 44411940)
    • (2006) American Journal of Pathology , vol.169 , Issue.3 , pp. 729-737
    • Nhan, T.Q.1    Liles, W.C.2    Schwartz, S.M.3
  • 53
    • 18244392443 scopus 로고    scopus 로고
    • Cell death independent of caspases: A review
    • DOI 10.1158/1078-0432.CCR-04-2223
    • Bröker LE, Kruyt FAE and Giaccone G: Cell death independent of caspases: a review. Clin Cancer Res 11: 3155-3162, 2005. (Pubitemid 40627860)
    • (2005) Clinical Cancer Research , vol.11 , Issue.9 , pp. 3155-3162
    • Broker, L.E.1    Kruyt, F.A.E.2    Giaccone, G.3
  • 54
    • 9944257505 scopus 로고    scopus 로고
    • L-sensitive, caspase-independent and characterized by massive cytoplasmic vacuole formation
    • DOI 10.1038/sj.cdd.4401503
    • Naumann U, Wischhusen J, Weit S, Rieger J Wolburg H, Massing U and Weller M: Alkylphosphocholine-induced glioma cell death is BCL-XL-sensitive, caspase-independent and characterized by massive cytoplasmic vacuole formation. Cell Death Differ 11: 1326-1341, 2004. (Pubitemid 39591778)
    • (2004) Cell Death and Differentiation , vol.11 , Issue.12 , pp. 1326-1341
    • Naumann, U.1    Wischhusen, J.2    Weit, S.3    Rieger, J.4    Wolburg, H.5    Massing, U.6    Weller, M.7
  • 56
    • 0027512151 scopus 로고
    • Inhibition of basal and TGFbeta-induced fibroblast collagen synthesis by antineoplastic agents. Implications for wound healing
    • Hendriks T, Martens MF, Huyben CM and Wobbes T: Inhibition of basal and TGFJ-induced fibroblast collagen synthesis by anti-neoplastic agents. Implications for wound healing. Br J Cancer 67: 545-550, 1993. (Pubitemid 23077650)
    • (1993) British Journal of Cancer , vol.67 , Issue.3 , pp. 545-550
    • Hendriks, T.1    Martens, M.F.W.C.2    Huyben, C.M.L.C.3    Wobbes, T.4
  • 57
    • 0141890240 scopus 로고    scopus 로고
    • Transcriptional inhibition of type I collagen gene expression in scleroderma fibroblasts by the antineoplastic drug ecteinascidin 743
    • DOI 10.1074/jbc.M301964200
    • Louneva N, Saitta B, Herrick DJ and Jimenez SA: Transcriptional inhibition of type I collagen gene expression in scleroderma fibroblasts by the antineoplastic drug ecteinascidin 743. J Biol Chem 278: 40400-40407, 2003. (Pubitemid 37248609)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.41 , pp. 40400-40407
    • Louneva, N.1    Saitta, B.2    Herrick, D.J.3    Jimenez, S.A.4
  • 58
    • 84861559414 scopus 로고    scopus 로고
    • In vitro analyses of the anti-fibrotic effect of SPARC silencing in human Tenon's fibroblasts: Comparisons with mitomycin C
    • Seet LF, Su R, Toh LZ and Wong TT: In vitro analyses of the anti-fibrotic effect of SPARC silencing in human Tenon's fibroblasts: comparisons with mitomycin C. J Cell Mol Med 16: 1245-1259, 2012.
    • (2012) J Cell Mol Med , vol.16 , pp. 1245-1259
    • Seet, L.F.1    Su, R.2    Toh, L.Z.3    Wong, T.T.4
  • 59
    • 77149157822 scopus 로고    scopus 로고
    • Colorectal cancer cell lines lack the molecular heterogeneity of clinical colorectal tumors
    • Auman JT and McLeod HL: Colorectal cancer cell lines lack the molecular heterogeneity of clinical colorectal tumors. Clin Colorectal Cancer 9: 40-47, 2010.
    • (2010) Clin Colorectal Cancer , vol.9 , pp. 40-47
    • Auman, J.T.1    McLeod, H.L.2


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