-
1
-
-
84879783987
-
Pharmacokinetic and pharmacodynamic analysis of 5-aza-2′- deoxycytidine (decitabine) in the design of its dose-schedule for cancer therapy
-
1:CAS:528:DC%2BC3sXjslCisbk%3D 10.1186/1868-7083-5-3
-
Karahoca M, Momparler RL (2013) Pharmacokinetic and pharmacodynamic analysis of 5-aza-2′-deoxycytidine (decitabine) in the design of its dose-schedule for cancer therapy. Clin Epigenet 5:3
-
(2013)
Clin Epigenet
, vol.5
, pp. 3
-
-
Karahoca, M.1
Momparler, R.L.2
-
2
-
-
84878635720
-
DNA methyltransferase inhibitors as epigenetic therapy for cancer
-
1:CAS:528:DC%2BC3sXpslKhtbc%3D 23517596 10.2174/15680096113139990077
-
Singh V, Sharma P, Capalash N (2013) DNA methyltransferase inhibitors as epigenetic therapy for cancer. Curr Cancer Drug Targets 13:379-399
-
(2013)
Curr Cancer Drug Targets
, vol.13
, pp. 379-399
-
-
Singh, V.1
Sharma, P.2
Capalash, N.3
-
3
-
-
0035057219
-
Activation of the p53 DNA damage response pathway after inhibition of DNA methyltransferase by 5-aza-2′-deoxycytidine
-
1:CAS:528:DC%2BD3MXisVSqsro%3D 11259619
-
Karpf AR, Moore BC, Ririe TO, Jones DA (2001) Activation of the p53 DNA damage response pathway after inhibition of DNA methyltransferase by 5-aza-2′-deoxycytidine. Mol Pharmacol 59:751-757
-
(2001)
Mol Pharmacol
, vol.59
, pp. 751-757
-
-
Karpf, A.R.1
Moore, B.C.2
Ririe, T.O.3
Jones, D.A.4
-
4
-
-
67549112510
-
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion
-
2687718 19243594 10.1186/bcr2232
-
Eiseler T, Doppler H, Yan IK, Goodison S, Storz P (2009) Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. Breast Cancer Res 11:R13
-
(2009)
Breast Cancer Res
, vol.11
, pp. 13
-
-
Eiseler, T.1
Doppler, H.2
Yan, I.K.3
Goodison, S.4
Storz, P.5
-
5
-
-
84884919327
-
Pharmacologic reversion of epigenetic silencing of the PRKD1 promoter blocks breast tumor cell invasion and metastasis
-
23971832 10.1186/bcr3460
-
Borges S, Doppler H, Perez EA, Andorfer CA, Sun Z et al (2013) Pharmacologic reversion of epigenetic silencing of the PRKD1 promoter blocks breast tumor cell invasion and metastasis. Breast Cancer Res 15:R66
-
(2013)
Breast Cancer Res
, vol.15
, pp. 66
-
-
Borges, S.1
Doppler, H.2
Perez, E.A.3
Andorfer, C.A.4
Sun, Z.5
-
6
-
-
0027234814
-
Increased immunodetection of acidic fibroblast growth factor in bladder cancer, detectable in urine
-
1:STN:280:DyaK3szotFymtw%3D%3D 7690426
-
Chopin DK, Caruelle JP, Colombel M, Palcy S, Ravery V et al (1993) Increased immunodetection of acidic fibroblast growth factor in bladder cancer, detectable in urine. J Urol 150:1126-1130
-
(1993)
J Urol
, vol.150
, pp. 1126-1130
-
-
Chopin, D.K.1
Caruelle, J.P.2
Colombel, M.3
Palcy, S.4
Ravery, V.5
-
7
-
-
0030981432
-
Basic fibroblast growth factor levels in cancer cells and in sera of patients suffering from proliferative disorders of the prostate
-
1:CAS:528:DyaK2sXlsFKqtL0%3D 9180932 10.1002/(SICI)1097-0045(19970601)31: 4<223: AID-PROS3>3.0.CO;2-L
-
Cronauer MV, Hittmair A, Eder IE, Hobisch A, Culig Z et al (1997) Basic fibroblast growth factor levels in cancer cells and in sera of patients suffering from proliferative disorders of the prostate. Prostate 31:223-233
-
(1997)
Prostate
, vol.31
, pp. 223-233
-
-
Cronauer, M.V.1
Hittmair, A.2
Eder, I.E.3
Hobisch, A.4
Culig, Z.5
-
8
-
-
0026603593
-
Immunohistochemical detection of acidic fibroblast growth factor in bladder transitional cell carcinoma
-
1:CAS:528:DyaK38Xks1OlsLc%3D 1377428 10.1007/BF00299719
-
Ravery V, Jouanneau J, Gil Diez S, Abbou CC, Caruelle JP et al (1992) Immunohistochemical detection of acidic fibroblast growth factor in bladder transitional cell carcinoma. Urol Res 20:211-214
-
(1992)
Urol Res
, vol.20
, pp. 211-214
-
-
Ravery, V.1
Jouanneau, J.2
Gil Diez, S.3
Abbou, C.C.4
Caruelle, J.P.5
-
9
-
-
0033899969
-
Increased expression of fibroblast growth factor 6 in human prostatic intraepithelial neoplasia and prostate cancer
-
1:CAS:528:DC%2BD3cXlvFOktLc%3D 10945637
-
Ropiquet F, Giri D, Kwabi-Addo B, Mansukhani A, Ittmann M (2000) Increased expression of fibroblast growth factor 6 in human prostatic intraepithelial neoplasia and prostate cancer. Cancer Res 60:4245-4250
-
(2000)
Cancer Res
, vol.60
, pp. 4245-4250
-
-
Ropiquet, F.1
Giri, D.2
Kwabi-Addo, B.3
Mansukhani, A.4
Ittmann, M.5
-
10
-
-
0027934194
-
Organ site-dependent expression of basic fibroblast growth factor in human renal cell carcinoma cells
-
1:CAS:528:DyaK2cXmt1Ols7c%3D 8053494
-
Singh RK, Bucana CD, Gutman M, Fan D, Wilson MR et al (1994) Organ site-dependent expression of basic fibroblast growth factor in human renal cell carcinoma cells. Am J Pathol 145:365-374
-
(1994)
Am J Pathol
, vol.145
, pp. 365-374
-
-
Singh, R.K.1
Bucana, C.D.2
Gutman, M.3
Fan, D.4
Wilson, M.R.5
-
11
-
-
0035161001
-
Predominant expression of fibroblast growth factor (FGF) 8, FGF4, and FGF receptor 1 in nonseminomatous and highly proliferative components of testicular germ cell tumors
-
1:CAS:528:DC%2BD3MXot1yksLY%3D 11764380
-
Suzuki K, Tokue A, Kamiakito T, Kuriki K, Saito K et al (2001) Predominant expression of fibroblast growth factor (FGF) 8, FGF4, and FGF receptor 1 in nonseminomatous and highly proliferative components of testicular germ cell tumors. Virchows Arch 439:616-621
-
(2001)
Virchows Arch
, vol.439
, pp. 616-621
-
-
Suzuki, K.1
Tokue, A.2
Kamiakito, T.3
Kuriki, K.4
Saito, K.5
-
12
-
-
0032804144
-
Suramin treatment of human glioma xenografts; Effects on tumor vasculature and oxygenation status
-
1:STN:280:DC%2BD3c%2FosVGitg%3D%3D 10619496 10.1023/A:1006363215260
-
Bernsen HJ, Rijken PF, Peters JP, Bakker JH, Boerman RH et al (1999) Suramin treatment of human glioma xenografts; effects on tumor vasculature and oxygenation status. J Neurooncol 44:129-136
-
(1999)
J Neurooncol
, vol.44
, pp. 129-136
-
-
Bernsen, H.J.1
Rijken, P.F.2
Peters, J.P.3
Bakker, J.H.4
Boerman, R.H.5
-
13
-
-
34548423634
-
Suramin inhibits not only tumor growth and metastasis but also angiogenesis in experimental pancreatic cancer
-
17390169 10.1007/s11605-006-0081-z
-
Bhargava S, Hotz B, Hines OJ, Reber HA, Buhr HJ et al (2007) Suramin inhibits not only tumor growth and metastasis but also angiogenesis in experimental pancreatic cancer. J Gastrointest Surg 11:171-178
-
(2007)
J Gastrointest Surg
, vol.11
, pp. 171-178
-
-
Bhargava, S.1
Hotz, B.2
Hines, O.J.3
Reber, H.A.4
Buhr, H.J.5
-
14
-
-
0027489946
-
Suramin inhibits bFGF-induced endothelial cell proliferation and angiogenesis in the chick chorioallantoic membrane
-
1:CAS:528:DyaK2cXhvVamsLs%3D 1968736 7692920 10.1038/bjc.1993.457
-
Danesi R, Del Bianchi S, Soldani P, Campagni A, La Rocca RV et al (1993) Suramin inhibits bFGF-induced endothelial cell proliferation and angiogenesis in the chick chorioallantoic membrane. Br J Cancer 68:932-938
-
(1993)
Br J Cancer
, vol.68
, pp. 932-938
-
-
Danesi, R.1
Del Bianchi, S.2
Soldani, P.3
Campagni, A.4
La Rocca, R.V.5
-
15
-
-
0017831729
-
Suramin: With special reference to onchocerciasis
-
1:CAS:528:DyaE1MXjtlKhtw%3D%3D 358805 10.1016/S1054-3589(08)60486-X
-
Hawking F (1978) Suramin: with special reference to onchocerciasis. Adv Pharmacol Chemother 15:289-322
-
(1978)
Adv Pharmacol Chemother
, vol.15
, pp. 289-322
-
-
Hawking, F.1
-
16
-
-
0023192594
-
Transforming growth factor alpha and beta expression in human colon cancer lines: Implications for an autocrine model
-
1:CAS:528:DyaL2sXlslems7k%3D 2887281
-
Coffey RJ Jr, Goustin AS, Soderquist AM, Shipley GD, Wolfshohl J et al (1987) Transforming growth factor alpha and beta expression in human colon cancer lines: implications for an autocrine model. Cancer Res 47:4590-4594
-
(1987)
Cancer Res
, vol.47
, pp. 4590-4594
-
-
Coffey, Jr.R.J.1
Goustin, A.S.2
Soderquist, A.M.3
Shipley, G.D.4
Wolfshohl, J.5
-
17
-
-
0022370712
-
Suramin binds to platelet-derived growth factor and inhibits its biological activity
-
1:CAS:528:DyaL28XivFCntw%3D%3D 4077932 10.1002/jcb.240290310
-
Hosang M (1985) Suramin binds to platelet-derived growth factor and inhibits its biological activity. J Cell Biochem 29:265-273
-
(1985)
J Cell Biochem
, vol.29
, pp. 265-273
-
-
Hosang, M.1
-
18
-
-
0025708218
-
Suramin blockade of insulinlike growth factor I-stimulated proliferation of human osteosarcoma cells
-
1:CAS:528:DyaK3cXmt1Chsr0%3D 2166171 10.1093/jnci/82.16.1349
-
Pollak M, Richard M (1990) Suramin blockade of insulinlike growth factor I-stimulated proliferation of human osteosarcoma cells. J Natl Cancer Inst 82:1349-1352
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 1349-1352
-
-
Pollak, M.1
Richard, M.2
-
19
-
-
0021327281
-
Platelet-derived growth factor receptors form a high affinity state in membrane preparations. Kinetics and affinity cross-linking studies
-
1:CAS:528:DyaL2cXhvVKnur8%3D 6325430
-
Williams LT, Tremble PM, Lavin MF, Sunday ME (1984) Platelet-derived growth factor receptors form a high affinity state in membrane preparations. Kinetics and affinity cross-linking studies. J Biol Chem 259:5287-5294
-
(1984)
J Biol Chem
, vol.259
, pp. 5287-5294
-
-
Williams, L.T.1
Tremble, P.M.2
Lavin, M.F.3
Sunday, M.E.4
-
20
-
-
0024461389
-
Suramin, an anti-cancer drug, inhibits protein kinase C and induces differentiation in neuroblastoma cell clone NB2A
-
1:CAS:528:DyaK3cXptFentQ%3D%3D 2591531 10.1016/0014-5793(89)81639-4
-
Hensey CE, Boscoboinik D, Azzi A (1989) Suramin, an anti-cancer drug, inhibits protein kinase C and induces differentiation in neuroblastoma cell clone NB2A. FEBS Lett 258:156-158
-
(1989)
FEBS Lett
, vol.258
, pp. 156-158
-
-
Hensey, C.E.1
Boscoboinik, D.2
Azzi, A.3
-
21
-
-
43649091528
-
Lysyl oxidase (LOX) mRNA expression and genes of the differentiated osteoblastic phenotype are upregulated in human osteosarcoma cells by suramin
-
1:CAS:528:DC%2BD1cXlvFyhsLg%3D 18374478 10.1016/j.canlet.2008.02.008
-
Buchinger B, Spitzer S, Karlic H, Klaushofer K, Varga F (2008) Lysyl oxidase (LOX) mRNA expression and genes of the differentiated osteoblastic phenotype are upregulated in human osteosarcoma cells by suramin. Cancer Lett 265:45-54
-
(2008)
Cancer Lett
, vol.265
, pp. 45-54
-
-
Buchinger, B.1
Spitzer, S.2
Karlic, H.3
Klaushofer, K.4
Varga, F.5
-
22
-
-
79951727653
-
Differentiation induction of mouse embryonic stem cells into sinus node-like cells by suramin
-
19775764 10.1016/j.ijcard.2009.08.021
-
Wiese C, Nikolova T, Zahanich I, Sulzbacher S, Fuchs J et al (2011) Differentiation induction of mouse embryonic stem cells into sinus node-like cells by suramin. Int J Cardiol 147:95-111
-
(2011)
Int J Cardiol
, vol.147
, pp. 95-111
-
-
Wiese, C.1
Nikolova, T.2
Zahanich, I.3
Sulzbacher, S.4
Fuchs, J.5
-
23
-
-
84868561310
-
Suramin inhibits the growth of nasopharyngeal carcinoma cells via the downregulation of osteopontin
-
1:CAS:528:DC%2BC38Xhs1ykurvI 22965338
-
Jiang S, Chen X, Li C, Zhang X, Zhang T et al (2012) Suramin inhibits the growth of nasopharyngeal carcinoma cells via the downregulation of osteopontin. Mol Med Rep 6:1351-1354
-
(2012)
Mol Med Rep
, vol.6
, pp. 1351-1354
-
-
Jiang, S.1
Chen, X.2
Li, C.3
Zhang, X.4
Zhang, T.5
-
24
-
-
0027298410
-
Suramin: A novel antineoplastic agent with multiple potential mechanisms of action
-
1:CAS:528:DyaK3sXks1ahtrs%3D 8485709
-
Stein CA (1993) Suramin: a novel antineoplastic agent with multiple potential mechanisms of action. Cancer Res 53:2239-2248
-
(1993)
Cancer Res
, vol.53
, pp. 2239-2248
-
-
Stein, C.A.1
-
25
-
-
84856032510
-
Protein kinase D1 maintains the epithelial phenotype by inducing a DNA-bound, inactive SNAI1 transcriptional repressor complex
-
1:CAS:528:DC%2BC38XitFeis7o%3D 3262827 22276203 10.1371/journal.pone. 0030459
-
Bastea LI, Doppler H, Balogun B, Storz P (2012) Protein kinase D1 maintains the epithelial phenotype by inducing a DNA-bound, inactive SNAI1 transcriptional repressor complex. PLoS ONE 7:e30459
-
(2012)
PLoS ONE
, vol.7
, pp. 30459
-
-
Bastea, L.I.1
Doppler, H.2
Balogun, B.3
Storz, P.4
-
26
-
-
78049284317
-
Protein kinase D1 suppresses epithelial-to-mesenchymal transition through phosphorylation of snail
-
1:CAS:528:DC%2BC3cXht1yqs7jP 20940406 10.1158/0008-5472.CAN-09-4481
-
Du C, Zhang C, Hassan S, Biswas MH, Balaji KC (2010) Protein kinase D1 suppresses epithelial-to-mesenchymal transition through phosphorylation of snail. Cancer Res 70:7810-7819
-
(2010)
Cancer Res
, vol.70
, pp. 7810-7819
-
-
Du, C.1
Zhang, C.2
Hassan, S.3
Biswas, M.H.4
Balaji, K.C.5
-
27
-
-
0038690400
-
Protein kinase C mu is down-regulated in androgen-independent prostate cancer
-
1:CAS:528:DC%2BD3sXlt1artLs%3D 12859948 10.1016/S0006-291X(03)01161-6
-
Jaggi M, Rao PS, Smith DJ, Hemstreet GP, Balaji KC (2003) Protein kinase C mu is down-regulated in androgen-independent prostate cancer. Biochem Biophys Res Commun 307:254-260
-
(2003)
Biochem Biophys Res Commun
, vol.307
, pp. 254-260
-
-
Jaggi, M.1
Rao, P.S.2
Smith, D.J.3
Hemstreet, G.P.4
Balaji, K.C.5
-
28
-
-
84879256921
-
Multi-level control of actin dynamics by protein kinase D
-
1:CAS:528:DC%2BC3sXhtVOrtbnK 23688773 10.1016/j.cellsig.2013.04.010
-
Olayioye MA, Barisic S, Hausser A (2013) Multi-level control of actin dynamics by protein kinase D. Cell Signal 25:1739-1747
-
(2013)
Cell Signal
, vol.25
, pp. 1739-1747
-
-
Olayioye, M.A.1
Barisic, S.2
Hausser, A.3
-
29
-
-
0038043212
-
Tyrosine phosphorylation of protein kinase D in the pleckstrin homology domain leads to activation
-
1:CAS:528:DC%2BD3sXjs1Kitbg%3D 12637538 10.1074/jbc.M213224200
-
Storz P, Doppler H, Johannes FJ, Toker A (2003) Tyrosine phosphorylation of protein kinase D in the pleckstrin homology domain leads to activation. J Biol Chem 278:17969-17976
-
(2003)
J Biol Chem
, vol.278
, pp. 17969-17976
-
-
Storz, P.1
Doppler, H.2
Johannes, F.J.3
Toker, A.4
-
30
-
-
66849099601
-
Mitochondrial diacylglycerol initiates protein-kinase D1-mediated ROS signaling
-
1:CAS:528:DC%2BD1MXlt1Oqsbg%3D 19258390 10.1242/jcs.041061
-
Cowell CF, Doppler H, Yan IK, Hausser A, Umezawa Y et al (2009) Mitochondrial diacylglycerol initiates protein-kinase D1-mediated ROS signaling. J Cell Sci 122:919-928
-
(2009)
J Cell Sci
, vol.122
, pp. 919-928
-
-
Cowell, C.F.1
Doppler, H.2
Yan, I.K.3
Hausser, A.4
Umezawa, Y.5
-
31
-
-
84866487200
-
An efficient procedure for protein extraction from formalin-fixed, paraffin-embedded tissues for reverse phase protein arrays
-
1:CAS:528:DC%2BC3sXivVOrt7w%3D 3561137 23006314 10.1186/1477-5956-10-56
-
Guo H, Liu W, Ju Z, Tamboli P, Jonasch E et al (2012) An efficient procedure for protein extraction from formalin-fixed, paraffin-embedded tissues for reverse phase protein arrays. Proteome Sci 10:56
-
(2012)
Proteome Sci
, vol.10
, pp. 56
-
-
Guo, H.1
Liu, W.2
Ju, Z.3
Tamboli, P.4
Jonasch, E.5
-
32
-
-
0026503826
-
Inhibition of breast cancer growth by suramin
-
1:STN:280:DyaK387kvVynuw%3D%3D 1738172 10.1093/jnci/84.1.38
-
Vignon F, Prebois C, Rochefort H (1992) Inhibition of breast cancer growth by suramin. J Natl Cancer Inst 84:38-42
-
(1992)
J Natl Cancer Inst
, vol.84
, pp. 38-42
-
-
Vignon, F.1
Prebois, C.2
Rochefort, H.3
-
33
-
-
4644265735
-
Low-dose suramin enhanced paclitaxel activity in chemotherapy-naive and paclitaxel-pretreated human breast xenograft tumors
-
1:CAS:528:DC%2BD2cXnvVOjsrw%3D 15447990 10.1158/1078-0432.CCR-04-0595
-
Song S, Yu B, Wei Y, Wientjes MG, Au JL (2004) Low-dose suramin enhanced paclitaxel activity in chemotherapy-naive and paclitaxel-pretreated human breast xenograft tumors. Clin Cancer Res 10:6058-6065
-
(2004)
Clin Cancer Res
, vol.10
, pp. 6058-6065
-
-
Song, S.1
Yu, B.2
Wei, Y.3
Wientjes, M.G.4
Au, J.L.5
-
34
-
-
0037414763
-
Protein kinase C phosphorylates protein kinase D activation loop Ser744 and Ser748 and releases autoinhibition by the pleckstrin homology domain
-
1:CAS:528:DC%2BD38XpvVWgtrk%3D 12407104 10.1074/jbc.M208075200
-
Waldron RT, Rozengurt E (2003) Protein kinase C phosphorylates protein kinase D activation loop Ser744 and Ser748 and releases autoinhibition by the pleckstrin homology domain. J Biol Chem 278:154-163
-
(2003)
J Biol Chem
, vol.278
, pp. 154-163
-
-
Waldron, R.T.1
Rozengurt, E.2
-
35
-
-
0032498119
-
Differential effects of suramin on protein kinase C isoenzymes. A novel tool for discriminating protein kinase C activities
-
1:CAS:528:DyaK1cXislyitw%3D%3D 9468299 10.1016/S0014-5793(97)01530-5
-
Gschwendt M, Kittstein W, Johannes FJ (1998) Differential effects of suramin on protein kinase C isoenzymes. A novel tool for discriminating protein kinase C activities. FEBS Lett 421:165-168
-
(1998)
FEBS Lett
, vol.421
, pp. 165-168
-
-
Gschwendt, M.1
Kittstein, W.2
Johannes, F.J.3
-
36
-
-
0033543570
-
Characterization of serine 916 as an in vivo autophosphorylation site for protein kinase D/Protein kinase Cmu
-
1:CAS:528:DyaK1MXmtVKlsL8%3D 10473617 10.1074/jbc.274.37.26543
-
Matthews SA, Rozengurt E, Cantrell D (1999) Characterization of serine 916 as an in vivo autophosphorylation site for protein kinase D/Protein kinase Cmu. J Biol Chem 274:26543-26549
-
(1999)
J Biol Chem
, vol.274
, pp. 26543-26549
-
-
Matthews, S.A.1
Rozengurt, E.2
Cantrell, D.3
-
37
-
-
70249100267
-
FOXO3a promotes tumor cell invasion through the induction of matrix metalloproteinases
-
1:CAS:528:DC%2BD1MXhtFCjs73M 2738298 19564415 10.1128/MCB.00077-09
-
Storz P, Doppler H, Copland JA, Simpson KJ, Toker A (2009) FOXO3a promotes tumor cell invasion through the induction of matrix metalloproteinases. Mol Cell Biol 29:4906-4917
-
(2009)
Mol Cell Biol
, vol.29
, pp. 4906-4917
-
-
Storz, P.1
Doppler, H.2
Copland, J.A.3
Simpson, K.J.4
Toker, A.5
-
38
-
-
0029827498
-
A phase I/II study of continuous infusion suramin in patients with hormone-refractory prostate cancer: Toxicity and response
-
1:CAS:528:DyaK2sXis1Wqu78%3D 8995493 10.1007/s002800050531
-
Bowden CJ, Figg WD, Dawson NA, Sartor O, Bitton RJ et al (1996) A phase I/II study of continuous infusion suramin in patients with hormone-refractory prostate cancer: toxicity and response. Cancer Chemother Pharmacol 39:1-8
-
(1996)
Cancer Chemother Pharmacol
, vol.39
, pp. 1-8
-
-
Bowden, C.J.1
Figg, W.D.2
Dawson, N.A.3
Sartor, O.4
Bitton, R.J.5
-
39
-
-
0032785794
-
Phase II trial of suramin in patients with metastatic renal cell carcinoma
-
1:CAS:528:DC%2BD3cXkslCquw%3D%3D 10638490 10.1023/A:1006331518952
-
Dreicer R, Smith DC, Williams RD, See WA (1999) Phase II trial of suramin in patients with metastatic renal cell carcinoma. Invest New Drugs 17:183-186
-
(1999)
Invest New Drugs
, vol.17
, pp. 183-186
-
-
Dreicer, R.1
Smith, D.C.2
Williams, R.D.3
See, W.A.4
-
40
-
-
0028850948
-
Suramin in patients with metastatic colorectal cancer pretreated with fluoropyrimidine-based chemotherapy. A phase II study
-
1:STN:280:DyaK2M7ht1agsw%3D%3D 7812913 10.1002/1097-0142(19950115)75: 2<440: AID-CNCR2820750205>3.0.CO;2-3
-
Falcone A, Pfanner E, Cianci C, Danesi R, Brunetti I et al (1995) Suramin in patients with metastatic colorectal cancer pretreated with fluoropyrimidine-based chemotherapy. A phase II study. Cancer 75:440-443
-
(1995)
Cancer
, vol.75
, pp. 440-443
-
-
Falcone, A.1
Pfanner, E.2
Cianci, C.3
Danesi, R.4
Brunetti, I.5
-
41
-
-
58149178174
-
Phase I/II trial of 5-fluorouracil and a noncytotoxic dose level of suramin in patients with metastatic renal cell carcinoma
-
1:CAS:528:DC%2BD1cXhtlWnurzI 2877588 18824429 10.3816/CGC.2008.n.012
-
George S, Dreicer R, Au JJ, Shen T, Rini BI et al (2008) Phase I/II trial of 5-fluorouracil and a noncytotoxic dose level of suramin in patients with metastatic renal cell carcinoma. Clin Genitourin Cancer 6:79-85
-
(2008)
Clin Genitourin Cancer
, vol.6
, pp. 79-85
-
-
George, S.1
Dreicer, R.2
Au, J.J.3
Shen, T.4
Rini, B.I.5
-
42
-
-
84863461112
-
Phase I/II trial of non-cytotoxic suramin in combination with weekly paclitaxel in metastatic breast cancer treated with prior taxanes
-
1:CAS:528:DC%2BC38XpsFajt7w%3D 3466596 22729159 10.1007/s00280-012-1887-x
-
Lustberg MB, Pant S, Ruppert AS, Shen T, Wei Y et al (2012) Phase I/II trial of non-cytotoxic suramin in combination with weekly paclitaxel in metastatic breast cancer treated with prior taxanes. Cancer Chemother Pharmacol 70:49-56
-
(2012)
Cancer Chemother Pharmacol
, vol.70
, pp. 49-56
-
-
Lustberg, M.B.1
Pant, S.2
Ruppert, A.S.3
Shen, T.4
Wei, Y.5
-
43
-
-
54949146895
-
Noncytotoxic suramin as a chemosensitizer in patients with advanced non-small-cell lung cancer: A phase II study
-
1:STN:280:DC%2BD1cnosVKitg%3D%3D 18632723 10.1093/annonc/mdn412
-
Villalona-Calero MA, Otterson GA, Wientjes MG, Weber F, Bekaii-Saab T et al (2008) Noncytotoxic suramin as a chemosensitizer in patients with advanced non-small-cell lung cancer: a phase II study. Ann Oncol 19:1903-1909
-
(2008)
Ann Oncol
, vol.19
, pp. 1903-1909
-
-
Villalona-Calero, M.A.1
Otterson, G.A.2
Wientjes, M.G.3
Weber, F.4
Bekaii-Saab, T.5
-
44
-
-
10744226335
-
Phase i study of low-dose suramin as a chemosensitizer in patients with advanced non-small cell lung cancer
-
1:CAS:528:DC%2BD3sXotFCksLk%3D 12960116
-
Villalona-Calero MA, Wientjes MG, Otterson GA, Kanter S, Young D et al (2003) Phase I study of low-dose suramin as a chemosensitizer in patients with advanced non-small cell lung cancer. Clin Cancer Res 9:3303-3311
-
(2003)
Clin Cancer Res
, vol.9
, pp. 3303-3311
-
-
Villalona-Calero, M.A.1
Wientjes, M.G.2
Otterson, G.A.3
Kanter, S.4
Young, D.5
-
45
-
-
12944272151
-
Fibroblast growth factors: An epigenetic mechanism of broad spectrum resistance to anticancer drugs
-
1:CAS:528:DC%2BD3cXlt1GnsLg%3D 27004 10890892 10.1073/pnas.140210697
-
Song S, Wientjes MG, Gan Y, Au JL (2000) Fibroblast growth factors: an epigenetic mechanism of broad spectrum resistance to anticancer drugs. Proc Natl Acad Sci U S A 97:8658-8663
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 8658-8663
-
-
Song, S.1
Wientjes, M.G.2
Gan, Y.3
Au, J.L.4
-
46
-
-
0035881312
-
Nontoxic doses of suramin enhance activity of paclitaxel against lung metastases
-
1:CAS:528:DC%2BD3MXmt12ktLc%3D 11507065
-
Song S, Wientjes MG, Walsh C, Au JL (2001) Nontoxic doses of suramin enhance activity of paclitaxel against lung metastases. Cancer Res 61:6145-6150
-
(2001)
Cancer Res
, vol.61
, pp. 6145-6150
-
-
Song, S.1
Wientjes, M.G.2
Walsh, C.3
Au, J.L.4
-
47
-
-
0034761804
-
Nontoxic doses of suramin enhance activity of doxorubicin in prostate tumors
-
1:CAS:528:DC%2BD3MXnvV2qsLY%3D 11602651
-
Zhang Y, Song S, Yang F, Au JL, Wientjes MG (2001) Nontoxic doses of suramin enhance activity of doxorubicin in prostate tumors. J Pharmacol Exp Ther 299:426-433
-
(2001)
J Pharmacol Exp Ther
, vol.299
, pp. 426-433
-
-
Zhang, Y.1
Song, S.2
Yang, F.3
Au, J.L.4
Wientjes, M.G.5
-
48
-
-
0141995803
-
Reduced expression of oestrogen receptor beta in invasive breast cancer and its re-expression using DNA methyl transferase inhibitors in a cell line model
-
1:CAS:528:DC%2BD3sXovVCrtrk%3D 14517838 10.1002/path.1436
-
Skliris GP, Munot K, Bell SM, Carder PJ, Lane S et al (2003) Reduced expression of oestrogen receptor beta in invasive breast cancer and its re-expression using DNA methyl transferase inhibitors in a cell line model. J Pathol 201:213-220
-
(2003)
J Pathol
, vol.201
, pp. 213-220
-
-
Skliris, G.P.1
Munot, K.2
Bell, S.M.3
Carder, P.J.4
Lane, S.5
-
49
-
-
2442622595
-
5-Aza-2′-deoxycytidine activates the p53/p21Waf1/Cip1 pathway to inhibit cell proliferation
-
1:CAS:528:DC%2BD2cXivVKgs7w%3D 14722112 10.1074/jbc.M311703200
-
Zhu WG, Hileman T, Ke Y, Wang P, Lu S et al (2004) 5-Aza-2′- deoxycytidine activates the p53/p21Waf1/Cip1 pathway to inhibit cell proliferation. J Biol Chem 279:15161-15166
-
(2004)
J Biol Chem
, vol.279
, pp. 15161-15166
-
-
Zhu, W.G.1
Hileman, T.2
Ke, Y.3
Wang, P.4
Lu, S.5
-
50
-
-
0017409254
-
Functional striated muscle cells from non-myoblast precursors following 5-azacytidine treatment
-
1:CAS:528:DyaE2sXlt1OjtLc%3D 68440 10.1038/267364a0
-
Constantinides PG, Jones PA, Gevers W (1977) Functional striated muscle cells from non-myoblast precursors following 5-azacytidine treatment. Nature 267:364-366
-
(1977)
Nature
, vol.267
, pp. 364-366
-
-
Constantinides, P.G.1
Jones, P.A.2
Gevers, W.3
-
51
-
-
0018860957
-
Cellular differentiation, cytidine analogs and DNA methylation
-
1:CAS:528:DyaL3cXksVamsrw%3D 6156004 10.1016/0092-8674(80)90237-8
-
Jones PA, Taylor SM (1980) Cellular differentiation, cytidine analogs and DNA methylation. Cell 20:85-93
-
(1980)
Cell
, vol.20
, pp. 85-93
-
-
Jones, P.A.1
Taylor, S.M.2
-
52
-
-
67349096401
-
Protein kinase D1 regulates cofilin-mediated F-actin reorganization and cell motility through slingshot
-
1:CAS:528:DC%2BD1MXlt1Skt7o%3D 2761768 19329994 10.1038/ncb1861
-
Eiseler T, Doppler H, Yan IK, Kitatani K, Mizuno K et al (2009) Protein kinase D1 regulates cofilin-mediated F-actin reorganization and cell motility through slingshot. Nat Cell Biol 11:545-556
-
(2009)
Nat Cell Biol
, vol.11
, pp. 545-556
-
-
Eiseler, T.1
Doppler, H.2
Yan, I.K.3
Kitatani, K.4
Mizuno, K.5
-
53
-
-
77953315696
-
Protein kinase D controls actin polymerization and cell motility through phosphorylation of cortactin
-
1:CAS:528:DC%2BC3cXmvFaqsb0%3D 20363754 10.1074/jbc.M109.093880
-
Eiseler T, Hausser A, De Kimpe L, Van Lint J, Pfizenmaier K (2010) Protein kinase D controls actin polymerization and cell motility through phosphorylation of cortactin. J Biol Chem 285:18672-18683
-
(2010)
J Biol Chem
, vol.285
, pp. 18672-18683
-
-
Eiseler, T.1
Hausser, A.2
De Kimpe, L.3
Van Lint, J.4
Pfizenmaier, K.5
-
54
-
-
34548133221
-
PKD is recruited to sites of actin remodelling at the leading edge and negatively regulates cell migration
-
1:CAS:528:DC%2BD2sXpsFKmtL0%3D 17707375 10.1016/j.febslet.2007.07.079
-
Eiseler T, Schmid MA, Topbas F, Pfizenmaier K, Hausser A (2007) PKD is recruited to sites of actin remodelling at the leading edge and negatively regulates cell migration. FEBS Lett 581:4279-4287
-
(2007)
FEBS Lett
, vol.581
, pp. 4279-4287
-
-
Eiseler, T.1
Schmid, M.A.2
Topbas, F.3
Pfizenmaier, K.4
Hausser, A.5
-
55
-
-
67651005347
-
Protein kinase D regulates cell migration by direct phosphorylation of the cofilin phosphatase slingshot 1 like
-
1:CAS:528:DC%2BD1MXosV2msrk%3D 19567672 10.1158/0008-5472.CAN-09-0718
-
Peterburs P, Heering J, Link G, Pfizenmaier K, Olayioye MA et al (2009) Protein kinase D regulates cell migration by direct phosphorylation of the cofilin phosphatase slingshot 1 like. Cancer Res 69:5634-5638
-
(2009)
Cancer Res
, vol.69
, pp. 5634-5638
-
-
Peterburs, P.1
Heering, J.2
Link, G.3
Pfizenmaier, K.4
Olayioye, M.A.5
-
56
-
-
80053195284
-
Protein kinase D regulates cofilin activity through p21-activated kinase 4
-
1:CAS:528:DC%2BC3MXht1ajtbzL 21832093 10.1074/jbc.M111.259424
-
Spratley SJ, Bastea LI, Doppler H, Mizuno K, Storz P (2011) Protein kinase D regulates cofilin activity through p21-activated kinase 4. J Biol Chem 286:34254-34261
-
(2011)
J Biol Chem
, vol.286
, pp. 34254-34261
-
-
Spratley, S.J.1
Bastea, L.I.2
Doppler, H.3
Mizuno, K.4
Storz, P.5
-
57
-
-
40949147679
-
Epigenetic inactivation of protein kinase D1 in gastric cancer and its role in gastric cancer cell migration and invasion
-
1:CAS:528:DC%2BD1cXjsVamsb8%3D 18283041 10.1093/carcin/bgm291
-
Kim M, Jang HR, Kim JH, Noh SM, Song KS et al (2008) Epigenetic inactivation of protein kinase D1 in gastric cancer and its role in gastric cancer cell migration and invasion. Carcinogenesis 29:629-637
-
(2008)
Carcinogenesis
, vol.29
, pp. 629-637
-
-
Kim, M.1
Jang, H.R.2
Kim, J.H.3
Noh, S.M.4
Song, K.S.5
-
58
-
-
84861790526
-
PKD1 negatively regulates cell invasion, migration and proliferation ability of human osteosarcoma
-
1:CAS:528:DC%2BC38XnvFeltrY%3D 22426824
-
Onishi Y, Kawamoto T, Kishimoto K, Hara H, Fukase N et al (2012) PKD1 negatively regulates cell invasion, migration and proliferation ability of human osteosarcoma. Int J Oncol 40:1839-1848
-
(2012)
Int J Oncol
, vol.40
, pp. 1839-1848
-
-
Onishi, Y.1
Kawamoto, T.2
Kishimoto, K.3
Hara, H.4
Fukase, N.5
-
59
-
-
33947214077
-
Chaetocin: A promising new antimyeloma agent with in vitro and in vivo activity mediated via imposition of oxidative stress
-
1:CAS:528:DC%2BD2sXnslygtr8%3D 17090648 10.1182/blood-2006-07-027326
-
Isham CR, Tibodeau JD, Jin W, Xu R, Timm MM et al (2007) Chaetocin: a promising new antimyeloma agent with in vitro and in vivo activity mediated via imposition of oxidative stress. Blood 109:2579-2588
-
(2007)
Blood
, vol.109
, pp. 2579-2588
-
-
Isham, C.R.1
Tibodeau, J.D.2
Jin, W.3
Xu, R.4
Timm, M.M.5
-
60
-
-
84859868412
-
Curcumin attenuates beta-catenin signaling in prostate cancer cells through activation of protein kinase D1
-
1:CAS:528:DC%2BC38Xmtlamsbw%3D 3327669 22523587 10.1371/journal.pone. 0035368
-
Sundram V, Chauhan SC, Ebeling M, Jaggi M (2012) Curcumin attenuates beta-catenin signaling in prostate cancer cells through activation of protein kinase D1. PLoS ONE 7:e35368
-
(2012)
PLoS ONE
, vol.7
, pp. 35368
-
-
Sundram, V.1
Chauhan, S.C.2
Ebeling, M.3
Jaggi, M.4
|