메뉴 건너뛰기




Volumn 55, Issue 1, 2014, Pages 337-344

Systemic upregulation of PDGF-B in patients with neovascular AMD

Author keywords

Diabetic retinopathy; HIF 1; Neovascular age related macular degeneration; PDGF B; Plasma levels; TNF

Indexed keywords

GLYCOSYLATED HEMOGLOBIN; PLATELET DERIVED GROWTH FACTOR B; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

EID: 84896699328     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.13-12978     Document Type: Article
Times cited : (29)

References (47)
  • 1
    • 84881336175 scopus 로고    scopus 로고
    • Ocular neovascularization
    • Campochiaro PA. Ocular neovascularization. J Mol Med (Berl). 2013;91:311-321.
    • (2013) J Mol Med (Berl) , vol.91 , pp. 311-321
    • Campochiaro, P.A.1
  • 2
    • 0028063245 scopus 로고
    • Platelet-derived growth factor ligands and receptors immunolocalized in proliferative retinal diseases
    • Robbins SG, Mixon RN, Wilson DJ, et al. Platelet-derived growth factor ligands and receptors immunolocalized in proliferative retinal diseases. Invest Ophthalmol Vis Sci. 1994;35:3649-3663.
    • (1994) Invest Ophthalmol Vis Sci , vol.35 , pp. 3649-3663
    • Robbins, S.G.1    Mixon, R.N.2    Wilson, D.J.3
  • 3
    • 2942682933 scopus 로고    scopus 로고
    • Insight into the physiological functions of PDGF through genetic studies in mice
    • Betsholtz C. Insight into the physiological functions of PDGF through genetic studies in mice. Cytokine Growth Factor Rev. 2004;15:215-228.
    • (2004) Cytokine Growth Factor Rev , vol.15 , pp. 215-228
    • Betsholtz, C.1
  • 4
    • 1642321880 scopus 로고    scopus 로고
    • Inhibition of platelet-derived growth factor promotes pericyte loss and angiogenesis in ischemic retinopathy
    • Wilkinson-Berka JL, Babic S, De Gooyer T, et al. Inhibition of platelet-derived growth factor promotes pericyte loss and angiogenesis in ischemic retinopathy. Am J Pathol. 2004;164: 1263-1273.
    • (2004) Am J Pathol , vol.164 , pp. 1263-1273
    • Wilkinson-Berka, J.L.1    Babic, S.2    de Gooyer, T.3
  • 5
    • 33847344251 scopus 로고    scopus 로고
    • Review of the pericyte during angiogenesis and its role in cancer and diabetic retinopathy
    • Hall AP. Review of the pericyte during angiogenesis and its role in cancer and diabetic retinopathy. Toxicol Pathol. 2006;34: 763-775.
    • (2006) Toxicol Pathol , vol.34 , pp. 763-775
    • Hall, A.P.1
  • 6
    • 34247853560 scopus 로고    scopus 로고
    • An antibody directed against PDGF receptor beta enhances the antitumor and the antiangiogenic activities of an anti-VEGF receptor 2 antibody
    • Shen J, Vil MD, Zhang H, et al. An antibody directed against PDGF receptor beta enhances the antitumor and the antiangiogenic activities of an anti-VEGF receptor 2 antibody. Biochem Biophys Res Commun. 2007;357:1142-1147.
    • (2007) Biochem Biophys Res Commun , vol.357 , pp. 1142-1147
    • Shen, J.1    Vil, M.D.2    Zhang, H.3
  • 7
    • 0038476608 scopus 로고    scopus 로고
    • Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors
    • Bergers G, Song S, Meyer-Morse N, Bergsland E, Hanahan D. Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors. J Clin Invest. 2003; 111:1287-1295.
    • (2003) J Clin Invest , vol.111 , pp. 1287-1295
    • Bergers, G.1    Song, S.2    Meyer-Morse, N.3    Bergsland, E.4    Hanahan, D.5
  • 8
    • 0031834239 scopus 로고    scopus 로고
    • A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF
    • Benjamin LE, Hemo I, Keshet E. A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development. 1998;125:1591-1598.
    • (1998) Development , vol.125 , pp. 1591-1598
    • Benjamin, L.E.1    Hemo, I.2    Keshet, E.3
  • 9
    • 84878105372 scopus 로고    scopus 로고
    • Contribution of TNF-alpha to the development of retinal neurodegenerative disorders
    • Al-Gayyar MM, Elsherbiny NM. Contribution of TNF-alpha to the development of retinal neurodegenerative disorders. Eur Cytokine Netw. 2013;24:27-36.
    • (2013) Eur Cytokine Netw , vol.24 , pp. 27-36
    • Al-Gayyar, M.M.1    Elsherbiny, N.M.2
  • 10
    • 70350238360 scopus 로고    scopus 로고
    • Unraveling a multifactorial late-onset disease: From genetic susceptibility to disease mechanisms for age-related macular degeneration
    • Swaroop A, Chew EY, Rickman CB, Abecasis GR. Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degeneration. Annu Rev Genomics Hum Genet. 2009;10:19-43.
    • (2009) Annu Rev Genomics Hum Genet , vol.10 , pp. 19-43
    • Swaroop, A.1    Chew, E.Y.2    Rickman, C.B.3    Abecasis, G.R.4
  • 11
    • 0037444823 scopus 로고    scopus 로고
    • Hypoxiainducible factor induction by tumour necrosis factor in normoxic cells requires receptor-interacting protein-dependent nuclear factor kappa B activation
    • Jung Y, Isaacs JS, Lee S, Trepel J, Liu ZG, Neckers L. Hypoxiainducible factor induction by tumour necrosis factor in normoxic cells requires receptor-interacting protein-dependent nuclear factor kappa B activation. Biochem J. 2003;370: 1011-1017.
    • (2003) Biochem J , vol.370 , pp. 1011-1017
    • Jung, Y.1    Isaacs, J.S.2    Lee, S.3    Trepel, J.4    Liu, Z.G.5    Neckers, L.6
  • 12
    • 0032819686 scopus 로고    scopus 로고
    • The potential angiogenic role of macrophages in the formation of choroidal neovascular membranes
    • Oh H, Takagi H, Takagi C, et al. The potential angiogenic role of macrophages in the formation of choroidal neovascular membranes. Invest Ophthalmol Vis Sci. 1999;40:1891-1898.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , pp. 1891-1898
    • Oh, H.1    Takagi, H.2    Takagi, C.3
  • 13
    • 33746234763 scopus 로고    scopus 로고
    • Tumor necrosis factoralpha induces endothelial dysfunction in the prediabetic metabolic syndrome
    • Picchi A, Gao X, Belmadani S, et al. Tumor necrosis factoralpha induces endothelial dysfunction in the prediabetic metabolic syndrome. Circ Res. 2006;99:69-77.
    • (2006) Circ Res , vol.99 , pp. 69-77
    • Picchi, A.1    Gao, X.2    Belmadani, S.3
  • 14
    • 42449135678 scopus 로고    scopus 로고
    • Immunological mechanisms in the pathogenesis of diabetic retinopathy
    • Adamis AP, Berman AJ. Immunological mechanisms in the pathogenesis of diabetic retinopathy. Semin Immunopathol. 2008;30:65-84.
    • (2008) Semin Immunopathol , vol.30 , pp. 65-84
    • Adamis, A.P.1    Berman, A.J.2
  • 15
    • 84871250502 scopus 로고    scopus 로고
    • High vitreous concentration of IL-6 and IL-8, but not of adhesion molecules in relation to plasma concentrations in proliferative diabetic retinopathy
    • Koskela UE, Kuusisto SM, Nissinen AE, Savolainen MJ, Liinamaa MJ. High vitreous concentration of IL-6 and IL-8, but not of adhesion molecules in relation to plasma concentrations in proliferative diabetic retinopathy. Ophthalmic Res. 2013;49: 108-114.
    • (2013) Ophthalmic Res , vol.49 , pp. 108-114
    • Koskela, U.E.1    Kuusisto, S.M.2    Nissinen, A.E.3    Savolainen, M.J.4    Liinamaa, M.J.5
  • 16
    • 84859891447 scopus 로고    scopus 로고
    • Role of intravitreal inflammatory cytokines and angiogenic factors in proliferative diabetic retinopathy
    • Zhou J, Wang S, Xia X. Role of intravitreal inflammatory cytokines and angiogenic factors in proliferative diabetic retinopathy. Curr Eye Res. 2012;37:416-420.
    • (2012) Curr Eye Res , vol.37 , pp. 416-420
    • Zhou, J.1    Wang, S.2    Xia, X.3
  • 17
    • 77956586572 scopus 로고    scopus 로고
    • Plasma levels of vascular endothelial growth factor and pigment epithelium-derived factor before and after intravitreal injection of bevacizumab
    • Matsuyama K, Ogata N, Matsuoka M, Wada M, Takahashi K, Nishimura T. Plasma levels of vascular endothelial growth factor and pigment epithelium-derived factor before and after intravitreal injection of bevacizumab. Br J Ophthalmol. 2010; 94:1215-1218.
    • (2010) Br J Ophthalmol , vol.94 , pp. 1215-1218
    • Matsuyama, K.1    Ogata, N.2    Matsuoka, M.3    Wada, M.4    Takahashi, K.5    Nishimura, T.6
  • 18
    • 84875213214 scopus 로고    scopus 로고
    • Plasma levels of vascular endothelial growth factor before and after intravitreal injection of bevacizumab, ranibizumab and pegaptanib in patients with age-related macular degeneration, and in patients with diabetic macular oedema
    • Zehetner C, Kirchmair R, Huber S, Kralinger MT, Kieselbach GF. Plasma levels of vascular endothelial growth factor before and after intravitreal injection of bevacizumab, ranibizumab and pegaptanib in patients with age-related macular degeneration, and in patients with diabetic macular oedema. Br J Ophthalmol. 2013;97:454-459.
    • (2013) Br J Ophthalmol , vol.97 , pp. 454-459
    • Zehetner, C.1    Kirchmair, R.2    Huber, S.3    Kralinger, M.T.4    Kieselbach, G.F.5
  • 19
    • 84856539058 scopus 로고    scopus 로고
    • Vascular endothelial growth factor plasma levels before and after treatment of neovascular age-related macular degeneration with bevacizumab or ranibizumab
    • Carneiro AM, Costa R, Falcao MS, et al. Vascular endothelial growth factor plasma levels before and after treatment of neovascular age-related macular degeneration with bevacizumab or ranibizumab. Acta Ophthalmol. 2012;90:e25-e30.
    • (2012) Acta Ophthalmol , vol.90
    • Carneiro, A.M.1    Costa, R.2    Falcao, M.S.3
  • 20
    • 84891627700 scopus 로고    scopus 로고
    • Humanized FcRn mouse models for evaluating pharmacokinetics of human IgG antibodies [published online ahead of print July 16, 2013]
    • doi:10.1016/j.ymeth.2013.07.005
    • Proetzel G, Roopenian DC. Humanized FcRn mouse models for evaluating pharmacokinetics of human IgG antibodies [published online ahead of print July 16, 2013]. Methods. doi:10.1016/j.ymeth.2013.07.005.
    • Methods
    • Proetzel, G.1    Roopenian, D.C.2
  • 21
    • 0037401890 scopus 로고    scopus 로고
    • VEGF-TRAP(R1R2) suppresses choroidal neovascularization and VEGF-induced breakdown of the blood-retinal barrier
    • Saishin Y, Saishin Y, Takahashi K, et al. VEGF-TRAP(R1R2) suppresses choroidal neovascularization and VEGF-induced breakdown of the blood-retinal barrier. J Cell Physiol. 2003; 195:241-248.
    • (2003) J Cell Physiol , vol.195 , pp. 241-248
    • Saishin, Y.1    Saishin, Y.2    Takahashi, K.3
  • 22
    • 77956980190 scopus 로고    scopus 로고
    • Infliximab for diabetic macular edema refractory to laser photocoagulation: A randomized, double-blind, placebo-controlled, crossover, 32-week study
    • Sfikakis PP, Grigoropoulos V, Emfietzoglou I, et al. Infliximab for diabetic macular edema refractory to laser photocoagulation: a randomized, double-blind, placebo-controlled, crossover, 32-week study. Diabetes Care. 2010;33:1523-1528.
    • (2010) Diabetes Care , vol.33 , pp. 1523-1528
    • Sfikakis, P.P.1    Grigoropoulos, V.2    Emfietzoglou, I.3
  • 23
    • 15044342651 scopus 로고    scopus 로고
    • Regression of neovascular age-related macular degeneration following infliximab therapy
    • Markomichelakis NN, Theodossiadis PG, Sfikakis PP. Regression of neovascular age-related macular degeneration following infliximab therapy. Am J Ophthalmol. 2005;139:537-540.
    • (2005) Am J Ophthalmol , vol.139 , pp. 537-540
    • Markomichelakis, N.N.1    Theodossiadis, P.G.2    Sfikakis, P.P.3
  • 24
    • 0042932653 scopus 로고    scopus 로고
    • Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales
    • Wilkinson CP, Ferris FL III, Klein RE, et al. Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales. Ophthalmology. 2003;110: 1677-1682.
    • (2003) Ophthalmology , vol.110 , pp. 1677-1682
    • Wilkinson, C.P.1    Ferris III, F.L.2    Klein, R.E.3
  • 25
    • 0036482285 scopus 로고    scopus 로고
    • Defining the relationship between plasma glucose and HbA(1c): Analysis of glucose profiles and HbA(1c) in the Diabetes Control and Complications Trial
    • Rohlfing CL, Wiedmeyer HM, Little RR, England JD, Tennill A, Goldstein DE. Defining the relationship between plasma glucose and HbA(1c): analysis of glucose profiles and HbA(1c) in the Diabetes Control and Complications Trial. Diabetes Care. 2002;25:275-278.
    • (2002) Diabetes Care , vol.25 , pp. 275-278
    • Rohlfing, C.L.1    Wiedmeyer, H.M.2    Little, R.R.3    England, J.D.4    Tennill, A.5    Goldstein, D.E.6
  • 26
    • 0027210562 scopus 로고
    • General involvement of hypoxiainducible factor 1 in transcriptional response to hypoxia
    • Wang GL, Semenza GL. General involvement of hypoxiainducible factor 1 in transcriptional response to hypoxia. Proc Natl Acad Sci U S A. 1993;90:4304-4308.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 4304-4308
    • Wang, G.L.1    Semenza, G.L.2
  • 27
    • 0032875460 scopus 로고    scopus 로고
    • Mechanism of action and in vivo role of platelet-derived growth factor
    • Heldin CH, Westermark B. Mechanism of action and in vivo role of platelet-derived growth factor. Physiolo Rev. 1999;79: 1283-1316.
    • (1999) Physiolo Rev , vol.79 , pp. 1283-1316
    • Heldin, C.H.1    Westermark, B.2
  • 28
    • 2942635366 scopus 로고    scopus 로고
    • PDGF and cardiovascular disease
    • Raines EW. PDGF and cardiovascular disease. Cytokine Growth Factor Rev. 2004;15:237-254.
    • (2004) Cytokine Growth Factor Rev , vol.15 , pp. 237-254
    • Raines, E.W.1
  • 30
    • 84877760753 scopus 로고    scopus 로고
    • The relationship of atherosclerosis to the 10-year cumulative incidence of agerelated macular degeneration: The Beaver Dam Studies
    • Klein R, Cruickshanks KJ, Myers CE, et al. The relationship of atherosclerosis to the 10-year cumulative incidence of agerelated macular degeneration: the Beaver Dam Studies. Ophthalmology. 2013;120:1012-1019.
    • (2013) Ophthalmology , vol.120 , pp. 1012-1019
    • Klein, R.1    Cruickshanks, K.J.2    Myers, C.E.3
  • 31
    • 28344438168 scopus 로고    scopus 로고
    • Biomarkers of cardiovascular disease as risk factors for agerelated macular degeneration
    • Vine AK, Stader J, Branham K, Musch DC, Swaroop A. Biomarkers of cardiovascular disease as risk factors for agerelated macular degeneration. Ophthalmology. 2005;112: 2076-2080.
    • (2005) Ophthalmology , vol.112 , pp. 2076-2080
    • Vine, A.K.1    Stader, J.2    Branham, K.3    Musch, D.C.4    Swaroop, A.5
  • 32
    • 0026418308 scopus 로고
    • Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody to PDGF
    • Ferns GA, Raines EW, Sprugel KH, Motani AS, Reidy MA, Ross R. Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody to PDGF. Science. 1991;253:1129-1132.
    • (1991) Science , vol.253 , pp. 1129-1132
    • Ferns, G.A.1    Raines, E.W.2    Sprugel, K.H.3    Motani, A.S.4    Reidy, M.A.5    Ross, R.6
  • 33
    • 0031458309 scopus 로고    scopus 로고
    • Egr-1 is activated in endothelial cells exposed to fluid shear stress and interacts with a novel shearstress-response element in the PDGF A-chain promoter
    • Khachigian LM, Anderson KR, Halnon NJ, Gimbrone MA Jr, Resnick N, Collins T. Egr-1 is activated in endothelial cells exposed to fluid shear stress and interacts with a novel shearstress-response element in the PDGF A-chain promoter. Arterioscl Thromb Vasc Biol. 1997;17:2280-2286.
    • (1997) Arterioscl Thromb Vasc Biol , vol.17 , pp. 2280-2286
    • Khachigian, L.M.1    Anderson, K.R.2    Halnon, N.J.3    Gimbrone Jr., M.A.4    Resnick, N.5    Collins, T.6
  • 35
    • 70449113602 scopus 로고    scopus 로고
    • Eye vessels saved by rescuing their pericyte partners
    • Antonetti D. Eye vessels saved by rescuing their pericyte partners. Nat Med. 2009;15:1248-1249.
    • (2009) Nat Med , vol.15 , pp. 1248-1249
    • Antonetti, D.1
  • 36
    • 70449108112 scopus 로고    scopus 로고
    • Activation of PKC-delta and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy
    • Geraldes P, Hiraoka-Yamamoto J, Matsumoto M, et al. Activation of PKC-delta and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy. Nat Med. 2009;15:1298-1306.
    • (2009) Nat Med , vol.15 , pp. 1298-1306
    • Geraldes, P.1    Hiraoka-Yamamoto, J.2    Matsumoto, M.3
  • 37
    • 18544366585 scopus 로고    scopus 로고
    • Endothelium-specific platelet-derived growth factor-B ablation mimics diabetic retinopathy
    • Enge M, Bjarnegard M, Gerhardt H, et al. Endothelium-specific platelet-derived growth factor-B ablation mimics diabetic retinopathy. EMBO J. 2002;21:4307-4316.
    • (2002) EMBO J , vol.21 , pp. 4307-4316
    • Enge, M.1    Bjarnegard, M.2    Gerhardt, H.3
  • 38
    • 0000675588 scopus 로고
    • Studies of the retinal capillaries in relation to diabetic and other retinopathies
    • Ashton N. Studies of the retinal capillaries in relation to diabetic and other retinopathies. Br J Ophthalmol. 1963;47: 521-538.
    • (1963) Br J Ophthalmol , vol.47 , pp. 521-538
    • Ashton, N.1
  • 39
    • 0034949457 scopus 로고    scopus 로고
    • Circulating plasma vascular endothelial growth factor and microvascular complications of type 1 diabetes mellitus: The influence of ACE inhibition
    • Chaturvedi N, Fuller JH, Pokras F, Rottiers R, Papazoglou N, Aiello LP. Circulating plasma vascular endothelial growth factor and microvascular complications of type 1 diabetes mellitus: the influence of ACE inhibition. Diabet Med. 2001; 18:288-294.
    • (2001) Diabet Med , vol.18 , pp. 288-294
    • Chaturvedi, N.1    Fuller, J.H.2    Pokras, F.3    Rottiers, R.4    Papazoglou, N.5    Aiello, L.P.6
  • 40
    • 84882732206 scopus 로고    scopus 로고
    • Correlation of vascular endothelial growth factor plasma levels and glycemic control in patients with diabetic retinopathy
    • Zehetner C, Kirchmair R, Kralinger M, Kieselbach G. Correlation of vascular endothelial growth factor plasma levels and glycemic control in patients with diabetic retinopathy. Acta Ophthalmol. 2013;91:e470-e473.
    • (2013) Acta Ophthalmol , vol.91
    • Zehetner, C.1    Kirchmair, R.2    Kralinger, M.3    Kieselbach, G.4
  • 41
    • 0004185166 scopus 로고    scopus 로고
    • TNF and TNFR biology in health and disease
    • McDermott MF. TNF and TNFR biology in health and disease. Cell Mol Biol (Noisy-le-grand). 2001;47:619-635.
    • (2001) Cell Mol Biol (Noisy-le-grand) , vol.47 , pp. 619-635
    • McDermott, M.F.1
  • 43
    • 84860179184 scopus 로고    scopus 로고
    • Antitumor necrosis factor alpha for retinal diseases: Current knowledge and future concepts
    • Mirshahi A, Hoehn R, Lorenz K, Kramann C, Baatz H. Antitumor necrosis factor alpha for retinal diseases: current knowledge and future concepts. J Ophthalmic Vis Res. 2012;7:39-44.
    • (2012) J Ophthalmic Vis Res , vol.7 , pp. 39-44
    • Mirshahi, A.1    Hoehn, R.2    Lorenz, K.3    Kramann, C.4    Baatz, H.5
  • 44
    • 34247209156 scopus 로고    scopus 로고
    • Tumor necrosis factor antagonists: Preliminary evidence for an emerging approach in the treatment of ocular inflammation
    • Theodossiadis PG, Markomichelakis NN, Sfikakis PP. Tumor necrosis factor antagonists: preliminary evidence for an emerging approach in the treatment of ocular inflammation. Retina. 2007;27:399-413.
    • (2007) Retina , vol.27 , pp. 399-413
    • Theodossiadis, P.G.1    Markomichelakis, N.N.2    Sfikakis, P.P.3
  • 46
    • 0036295180 scopus 로고    scopus 로고
    • Quantitative assessment of the integrity of the blood-retinal barrier in mice
    • Derevjanik NL, Vinores SA, Xiao WH, et al. Quantitative assessment of the integrity of the blood-retinal barrier in mice. Invest Ophthalmol Vis Sci. 2002;43:2462-2467.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 2462-2467
    • Derevjanik, N.L.1    Vinores, S.A.2    Xiao, W.H.3
  • 47
    • 57649227691 scopus 로고    scopus 로고
    • Agmatine protects cultured retinal ganglion cells from tumor necrosis factor-alpha-induced apoptosis
    • Hong S, Kim CY, Lee JE, Seong GJ. Agmatine protects cultured retinal ganglion cells from tumor necrosis factor-alpha-induced apoptosis. Life Sci. 2009;84:28-32.
    • (2009) Life Sci , vol.84 , pp. 28-32
    • Hong, S.1    Kim, C.Y.2    Lee, J.E.3    Seong, G.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.